| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lorenz Stude. Derivation of dopaminergic neurons from pluripotent stem cells. Progress in brain research. vol 200. 2013-11-15. PMID:23195422. |
however, several challenges remain such as the need to develop strategies that can enrich for selective subtypes of midbrain dopamine neurons, techniques to control postmitotic dopamine neuron maturation, and finally, clinical grade differentiation protocols that enable the production dopamine neurons suitable for human cell therapy. |
2013-11-15 |
2023-08-12 |
mouse |
| Thomas D Sambrook, Matthew Roser, Jeremy Gosli. Prospect theory does not describe the feedback-related negativity value function. Psychophysiology. vol 49. issue 12. 2013-11-12. PMID:23094592. |
a separate body of research claims that prediction errors are calculated by midbrain dopamine neurons. |
2013-11-12 |
2023-08-12 |
human |
| Masayuki Matsumoto, Masahiko Takad. Distinct representations of cognitive and motivational signals in midbrain dopamine neurons. Neuron. vol 79. issue 5. 2013-11-11. PMID:23932490. |
distinct representations of cognitive and motivational signals in midbrain dopamine neurons. |
2013-11-11 |
2023-08-12 |
monkey |
| Masayuki Matsumoto, Masahiko Takad. Distinct representations of cognitive and motivational signals in midbrain dopamine neurons. Neuron. vol 79. issue 5. 2013-11-11. PMID:23932490. |
our findings suggest an anatomical gradient of dopamine signals along the dorsolateral-ventromedial axis of the ventral midbrain. |
2013-11-11 |
2023-08-12 |
monkey |
| Michel Engeln, Stefania Fasano, Serge H Ahmed, Martine Cador, Veerle Baekelandt, Erwan Bezard, Pierre-Olivier Fernagu. Levodopa gains psychostimulant-like properties after nigral dopaminergic loss. Annals of neurology. vol 74. issue 1. 2013-11-07. PMID:23494678. |
these 2 effects may combine to explain the addictive use of levodopa after loss of midbrain dopamine neurons in some pd patients. |
2013-11-07 |
2023-08-12 |
rat |
| Matthew C Havrda, Brenton R Paolella, Nora M Ward, Kathryn B Holroy. Behavioral abnormalities and Parkinson's-like histological changes resulting from Id2 inactivation in mice. Disease models & mechanisms. vol 6. issue 3. 2013-10-29. PMID:23264561. |
these findings document a novel role for id2 in the maintenance of midbrain dopamine neurons. |
2013-10-29 |
2023-08-12 |
mouse |
| Stephan Steidl, Esther Lee, David Wasserman, John S Yeoman. Acute food deprivation reverses morphine-induced locomotion deficits in M5 muscarinic receptor knockout mice. Behavioural brain research. vol 252. 2013-10-28. PMID:23742799. |
m5 muscarinic cholinergic receptors, expressed by midbrain dopamine neurons, are critical for the ability of morphine to increase nucleus accumbens dopamine levels and locomotion, and for morphine cpp. |
2013-10-28 |
2023-08-12 |
mouse |
| Simon N Jacob, Torben Ott, Andreas Niede. Dopamine regulates two classes of primate prefrontal neurons that represent sensory signals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 34. 2013-10-28. PMID:23966694. |
the lateral prefrontal cortex (pfc), a hub of higher-level cognitive processing, is strongly modulated by midbrain dopamine (da) neurons. |
2013-10-28 |
2023-08-12 |
monkey |
| Yen Yu, Thomas H B FitzGerald, Karl J Fristo. Working memory and anticipatory set modulate midbrain and putamen activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986240. |
based on the known role of dopamine in cognitive flexibility and working memory updating, we hypothesized that differences in anticipatory set would be manifest in the dopaminergic midbrain and striatum. |
2013-10-28 |
2023-08-12 |
human |
| Paul Leon Brown, Paul D Shepar. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593280. |
midbrain dopamine neurons are an essential part of the circuitry underlying motivation and reinforcement. |
2013-10-22 |
2023-08-12 |
rat |
| Paul Leon Brown, Paul D Shepar. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593280. |
the lateral habenula (lhb), an epithalamic structure that forms reciprocal connections with midbrain dopamine neurons, shows the opposite response being activated by reward omission or aversive stimuli and inhibited by reward-predicting cues. |
2013-10-22 |
2023-08-12 |
rat |
| Paul Leon Brown, Paul D Shepar. Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23593280. |
it has been hypothesized that habenular input to midbrain dopamine neurons is conveyed via a feedforward inhibitory pathway involving the gabaergic mesopontine rostromedial tegmental area. |
2013-10-22 |
2023-08-12 |
rat |
| Mohammad Reza Zarrindast, Nafiseh Eslahi, Ameneh Rezayof, Parvin Rostami, Maryam Zahmatkes. Modulation of ventral tegmental area dopamine receptors inhibit nicotine-induced anxiogenic-like behavior in the central amygdala. Progress in neuro-psychopharmacology & biological psychiatry. vol 41. 2013-10-17. PMID:23178824. |
amygdala is directly implicated in anxiety modulation and sends projections to the vicinity of the midbrain dopamine neurons, including the ventral tegmental area (vta) which is a key area that controls nicotine dependence processes. |
2013-10-17 |
2023-08-12 |
rat |
| John D Elsworth, J David Jentsch, Catherine A Vandevoort, Robert H Roth, D Eugene Redmond, Csaba Lerant. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. Neurotoxicology. vol 35. 2013-09-10. PMID:23337607. |
prenatal exposure to bisphenol a impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. |
2013-09-10 |
2023-08-12 |
human |
| John D Elsworth, J David Jentsch, Catherine A Vandevoort, Robert H Roth, D Eugene Redmond, Csaba Lerant. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. Neurotoxicology. vol 35. 2013-09-10. PMID:23337607. |
previous research suggests that bpa preferentially targets dopamine neurons in ventral mesencephalon and glutamatergic neurons in hippocampus, so the present work examined the susceptibility of these systems to low dose bpa exposure at the fetal and juvenile stages of development in non-human primates. |
2013-09-10 |
2023-08-12 |
human |
| John D Elsworth, J David Jentsch, Catherine A Vandevoort, Robert H Roth, D Eugene Redmond, Csaba Lerant. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. Neurotoxicology. vol 35. 2013-09-10. PMID:23337607. |
specifically, light microscopy revealed a decrease in tyrosine hydroxylase-expressing (dopamine) neurons in the midbrain of bpa-exposed fetuses and electron microscopy identified a reduction in spine synapses in the ca1 region of hippocampus. |
2013-09-10 |
2023-08-12 |
human |
| Cristian Arredondo, Marcelo Orellana, Andrea Vecchiola, Luis Alberto Pereira, Leopoldo Galdames, María Estela André. PIASγ enhanced SUMO-2 modification of Nurr1 activation-function-1 domain limits Nurr1 transcriptional synergy. PloS one. vol 8. issue 1. 2013-09-06. PMID:23358114. |
nurr1 plays key roles in the origin and maintenance of midbrain dopamine neurons, and peripheral inflammatory processes. |
2013-09-06 |
2023-08-12 |
Not clear |
| Elizabeth E Steinberg, Ronald Keiflin, Josiah R Boivin, Ilana B Witten, Karl Deisseroth, Patricia H Jana. A causal link between prediction errors, dopamine neurons and learning. Nature neuroscience. vol 16. issue 7. 2013-09-03. PMID:23708143. |
unexpected rewards strongly activate midbrain dopamine neurons. |
2013-09-03 |
2023-08-12 |
rat |
| X Cui, M Pelekanos, P-Y Liu, T H J Burne, J J McGrath, D W Eyle. The vitamin D receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. Neuroscience. vol 236. 2013-08-26. PMID:23352937. |
the vitamin d receptor in dopamine neurons; its presence in human substantia nigra and its ontogenesis in rat midbrain. |
2013-08-26 |
2023-08-12 |
human |
| Anders Bjorklund, Jeffrey H Kordowe. Cell therapy for Parkinson's disease: what next? Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 1. 2013-08-21. PMID:23390097. |
the idea to use transplants of dopamine-producing cells to substitute for the lost midbrain dopamine neurons in parkinson's disease (pd) goes back to the 1970s. |
2013-08-21 |
2023-08-12 |
human |