| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam Melis, Simona Scheggi, Gianfranca Carta, Camilla Madeddu, Salvatore Lecca, Antonio Luchicchi, Francesca Cadeddu, Roberto Frau, Liana Fattore, Paola Fadda, M Grazia Ennas, M Paola Castelli, Walter Fratta, Bjorn Schilstrom, Sebastiano Banni, M Graziella De Montis, Marco Pisti. PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 14. 2013-05-28. PMID:23554501. |
pparα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. |
2013-05-28 |
2023-08-12 |
rat |
| Matthew J Wanat, Antonello Bonci, Paul E M Phillip. CRF acts in the midbrain to attenuate accumbens dopamine release to rewards but not their predictors. Nature neuroscience. vol 16. issue 4. 2013-05-21. PMID:23416448. |
crf acts in the midbrain to attenuate accumbens dopamine release to rewards but not their predictors. |
2013-05-21 |
2023-08-12 |
Not clear |
| Xiaojing Di, Jingqi Yan, Yan Zhao, Yanzhong Chang, Baolu Zha. L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway. Science China. Life sciences. vol 55. issue 12. 2013-05-17. PMID:23233221. |
further studies using high performance liquid chromatography, western blotting and immunofluorescence staining analyses showed that l-theanine significantly inhibited nicotine-induced tyrosine hydroxylase (th) expression and dopamine production in the midbrain of mice. |
2013-05-17 |
2023-08-12 |
mouse |
| Jürgen Innos, Este Leidmaa, Mari-Anne Philips, Silva Sütt, Aet Alttoa, Jaanus Harro, Sulev Kõks, Eero Vasa. Lsamp⁻/⁻ mice display lower sensitivity to amphetamine and have elevated 5-HT turnover. Biochemical and biophysical research communications. vol 430. issue 1. 2013-05-14. PMID:23206697. |
finally, lsamp(-/-) mice had lower level of dopamine transporter (dat) mrna in the mesencephalon. |
2013-05-14 |
2023-08-12 |
mouse |
| Christopher D Fiorillo, Sora R Yun, Minryung R Son. Diversity and homogeneity in responses of midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486943. |
diversity and homogeneity in responses of midbrain dopamine neurons. |
2013-05-06 |
2023-08-12 |
Not clear |
| Christopher D Fiorillo, Sora R Yun, Minryung R Son. Diversity and homogeneity in responses of midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486943. |
dopamine neurons of the ventral midbrain have been found to signal a reward prediction error that can mediate positive reinforcement. |
2013-05-06 |
2023-08-12 |
Not clear |
| Christopher D Fiorillo, Minryung R Song, Sora R Yu. Multiphasic temporal dynamics in responses of midbrain dopamine neurons to appetitive and aversive stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486944. |
multiphasic temporal dynamics in responses of midbrain dopamine neurons to appetitive and aversive stimuli. |
2013-05-06 |
2023-08-12 |
Not clear |
| J Halloran, S A Hussong, R Burbank, N Podlutskaya, K E Fischer, L B Sloane, S N Austad, R Strong, A Richardson, M J Hart, V Galva. Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. Neuroscience. vol 223. 2013-05-01. PMID:22750207. |
levels of three major monoamines (norepinephrine, dopamine and 5-hydroxytryptamine) and their metabolites (3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindolacetic acid) were significantly augmented in midbrain of rapamycin-treated mice compared to controls. |
2013-05-01 |
2023-08-12 |
mouse |
| Jasmine Yang, Ashly Brown, Debra Ellisor, Erin Paul, Nellwyn Hagan, Mark Zerva. Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development. Development (Cambridge, England). vol 140. issue 6. 2013-05-01. PMID:23444360. |
dynamic temporal requirement of wnt1 in midbrain dopamine neuron development. |
2013-05-01 |
2023-08-12 |
Not clear |
| Jasmine Yang, Ashly Brown, Debra Ellisor, Erin Paul, Nellwyn Hagan, Mark Zerva. Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development. Development (Cambridge, England). vol 140. issue 6. 2013-05-01. PMID:23444360. |
wnt1-expressing progenitors generate midbrain dopamine (mbda) and cerebellum (cb) neurons in distinct temporal windows and from spatially discrete progenitor domains. |
2013-05-01 |
2023-08-12 |
Not clear |
| Kristi A Kohlmeier, Masaru Ishibashi, Jürgen Wess, Martha E Bickford, Christopher S Leonar. Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus. Journal of neurophysiology. vol 108. issue 10. 2013-04-30. PMID:22956788. |
cholinergic neurons in the laterodorsal tegmental (ldt) and peduncolopontine tegmental (ppt) nuclei regulate reward, arousal, and sensory gating via major projections to midbrain dopamine regions, the thalamus, and pontine targets. |
2013-04-30 |
2023-08-12 |
mouse |
| David M Cole, Christian F Beckmann, Graham E Searle, Christophe Plisson, Andri C Tziortzi, Thomas E Nichols, Roger N Gunn, Paul M Matthews, Eugenii A Rabiner, John D Beave. Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 12. 2013-04-29. PMID:22186675. |
orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine d3 receptor availability. |
2013-04-29 |
2023-08-12 |
human |
| David M Cole, Christian F Beckmann, Graham E Searle, Christophe Plisson, Andri C Tziortzi, Thomas E Nichols, Roger N Gunn, Paul M Matthews, Eugenii A Rabiner, John D Beave. Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 12. 2013-04-29. PMID:22186675. |
these findings demonstrate that differential interactions between ofc and networks implicated in cognitive control and reward are associated with midbrain d3r availability, consistent with the hypothesis that dopamine d3r signaling is an important molecular pathway underlying goal-directed behavior. |
2013-04-29 |
2023-08-12 |
human |
| S J Moeller, D Tomasi, J Honorio, N D Volkow, R Z Goldstei. Dopaminergic involvement during mental fatigue in health and cocaine addiction. Translational psychiatry. vol 2. 2013-04-23. PMID:23092980. |
this midbrain fmri activity with repetition was further correlated with objective indices of endogenous motivation in all subjects: a state measure (task reaction time) and a trait measure (dopamine d2 receptor availability in caudate, as revealed by positron emission tomography data collected in a subset of this sample, which directly points to a contribution of dopamine to these results). |
2013-04-23 |
2023-08-12 |
human |
| S J Moeller, D Tomasi, J Honorio, N D Volkow, R Z Goldstei. Dopaminergic involvement during mental fatigue in health and cocaine addiction. Translational psychiatry. vol 2. 2013-04-23. PMID:23092980. |
in a second sample of 14 cocaine abusers and 15 controls, administration of an indirect dopamine agonist, methylphenidate, reversed these midbrain responses in both groups, possibly indicating normalization of response in cocaine abusers because of restoration of dopamine signaling but degradation of response in healthy controls owing to excessive dopamine signaling. |
2013-04-23 |
2023-08-12 |
human |
| Jingli Cai, Stephanie Schleidt, Joshua Pelta-Heller, Danielle Hutchings, Gregory Cannarsa, Lorraine Iacovitt. BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. Developmental biology. vol 376. issue 1. 2013-04-17. PMID:23352789. |
bmp and tgf-β pathway mediators are critical upstream regulators of wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. |
2013-04-17 |
2023-08-12 |
human |
| Jingli Cai, Stephanie Schleidt, Joshua Pelta-Heller, Danielle Hutchings, Gregory Cannarsa, Lorraine Iacovitt. BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells. Developmental biology. vol 376. issue 1. 2013-04-17. PMID:23352789. |
although many laboratories currently use small molecule inhibitors of the bmp (dorsomorphin/dm) and tgf-β (sb431542/sb) signaling pathways in protocols to generate midbrain dopamine (mda) neurons from hes and hips cells, until now, these substances have not been thought to play a role in the mda differentiation process. |
2013-04-17 |
2023-08-12 |
human |
| Tyrell J Simkins, Kelly L Janis, Alison K McClure, Bahareh Behrouz, Samuel S Pappas, Andreas Lehner, Norbert E Kaminski, John L Goudreau, Keith J Lookingland, Barbara L F Kapla. Comparison of the D2 receptor regulation and neurotoxicant susceptibility of nigrostriatal dopamine neurons in wild-type and CB1/CB2 receptor knockout mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 7. issue 3. 2013-04-10. PMID:22639229. |
motor dysfunctions of parkinson disease (pd) are due to the progressive loss of midbrain nigrostriatal dopamine (nsda) neurons. |
2013-04-10 |
2023-08-12 |
mouse |
| Banafsheh Kadkhodaei, Alexandra Alvarsson, Nicoletta Schintu, Daniel Ramsköld, Nikolaos Volakakis, Eliza Joodmardi, Takashi Yoshitake, Jan Kehr, Mickael Decressac, Anders Björklund, Rickard Sandberg, Per Svenningsson, Thomas Perlman. Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 6. 2013-04-09. PMID:23341612. |
the transcription factor nurr1 has been associated with parkinson's disease and is essential for the development of ventral midbrain dopamine (da) neurons. |
2013-04-09 |
2023-08-12 |
mouse |
| Miriam Melis, Marco Pisti. Hub and switches: endocannabinoid signalling in midbrain dopamine neurons. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1607. 2013-04-08. PMID:23108546. |
hub and switches: endocannabinoid signalling in midbrain dopamine neurons. |
2013-04-08 |
2023-08-12 |
Not clear |