| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel J Foster, Patrick R Gentry, Jose E Lizardi-Ortiz, Thomas M Bridges, Michael R Wood, Colleen M Niswender, David Sulzer, Craig W Lindsley, Zixiu Xiang, P Jeffrey Con. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 9. 2014-04-22. PMID:24573284. |
however, developing an understanding of the role of m5 in regulating midbrain dopamine neuron function has been hampered by a lack of subtype-selective compounds. |
2014-04-22 |
2023-08-12 |
mouse |
| M A Fahim, S Shehab, A Nemmar, A Adem, S Dhanasekaran, M Y Hasa. Daily subacute paraquat exposure decreases muscle function and substantia nigra dopamine level. Physiological research. vol 62. issue 3. 2014-04-21. PMID:23489189. |
dopamine concentrations in the ventral mesencephalon were measured by high performance liquid chromatography and the number of dopaminergic neurons in substantia nigra pars compacta was estimated by tyrosine hydroxylase immunohistochemistry. |
2014-04-21 |
2023-08-12 |
rat |
| Jie Liang, Jianhong Luo, Jinghur Ji. [Study of Parkinson's disease based on Drosophila model]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 42. issue 6. 2014-04-21. PMID:24421238. |
pd is the result of loss of a majority of dopamine (da) neurons in the midbrain substantia nigra. |
2014-04-21 |
2023-08-12 |
human |
| Susan H Fo. Non-dopaminergic treatments for motor control in Parkinson's disease. Drugs. vol 73. issue 13. 2014-04-10. PMID:23917951. |
the pathological processes underlying parkinson's disease (pd) involve more than dopamine cell loss within the midbrain. |
2014-04-10 |
2023-08-12 |
human |
| Natalie M Doig, Peter J Magill, Paul Apicella, J Paul Bolam, Andrew Sharot. Cortical and thalamic excitation mediate the multiphasic responses of striatal cholinergic interneurons to motivationally salient stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553950. |
in primates, tonically active neurons (putative cholinergic interneurons) exhibit multiphasic responses to motivationally salient stimuli that mirror those of midbrain dopamine neurons and together these two systems mediate reward-related learning in basal ganglia circuits. |
2014-04-10 |
2023-08-12 |
rat |
| Sang-Hoon Yi, Xi-Biao He, Yong-Hee Rhee, Chang-Hwan Park, Takumi Takizawa, Kinichi Nakashima, Sang-Hun Le. Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation. Development (Cambridge, England). vol 141. issue 4. 2014-04-09. PMID:24496614. |
understanding how dopamine (da) phenotypes are acquired in midbrain da (mda) neuron development is important for bioassays and cell replacement therapy for mda neuron-associated disorders. |
2014-04-09 |
2023-08-12 |
Not clear |
| Daniela Battista, Yosif Ganat, Abderrahman El Maarouf, Lorenz Studer, Urs Rutishause. Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice. Stem cells translational medicine. vol 3. issue 1. 2014-04-08. PMID:24311700. |
there has been considerable progress in obtaining engraftable embryonic stem (es) cell-derived midbrain dopamine neurons for cell replacement therapy in models of parkinson's disease; however, limited integration and striatal reinnervation of es-derived grafts remain a major challenge for future clinical translation. |
2014-04-08 |
2023-08-12 |
mouse |
| S R Suwijn, H W Berendse, C V M Verschuur, R M A de Bie, J Booi. Serotonin transporter availability in early stage Parkinson's disease and multiple system atrophy. ISRN neurology. vol 2014. 2014-04-02. PMID:24693450. |
we retrospectively assessed baseline midbrain sert availability as well as midbrain sert-to-striatal dopamine transporter (dat) ratios. |
2014-04-02 |
2023-08-13 |
Not clear |
| Alexander K Converse, Colleen F Moore, Jeffrey M Moirano, Elizabeth O Ahlers, Julie A Larson, Jonathan W Engle, Todd E Barnhart, Dhanabalan Murali, Bradley T Christian, Onofre T DeJesus, James E Holden, Robert J Nickles, Mary L Schneide. Prenatal stress induces increased striatal dopamine transporter binding in adult nonhuman primates. Biological psychiatry. vol 74. issue 7. 2014-03-25. PMID:23726316. |
to determine the effects in adult offspring of maternal exposure to stress and alcohol during pregnancy, we imaged striatal and midbrain dopamine transporter (dat) binding by positron emission tomography in rhesus monkeys (macaca mulatta). |
2014-03-25 |
2023-08-12 |
monkey |
| Keiichi Inoue, Joanne Rispoli, Lichuan Yang, David Macleod, M Flint Beal, Eric Klann, Asa Abeliovic. Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway. PLoS genetics. vol 9. issue 10. 2014-03-20. PMID:24098148. |
mature atg7-deficient midbrain dopamine (da) neurons harbored selectively enlarged axonal terminals. |
2014-03-20 |
2023-08-12 |
Not clear |
| Amanda L Brown, Trevor A Day, Christopher V Dayas, Doug W Smit. Purity and enrichment of laser-microdissected midbrain dopamine neurons. BioMed research international. vol 2013. 2014-03-18. PMID:23984404. |
purity and enrichment of laser-microdissected midbrain dopamine neurons. |
2014-03-18 |
2023-08-12 |
Not clear |
| Amanda L Brown, Trevor A Day, Christopher V Dayas, Doug W Smit. Purity and enrichment of laser-microdissected midbrain dopamine neurons. BioMed research international. vol 2013. 2014-03-18. PMID:23984404. |
here, we show that midbrain dopamine neurons can be laser-microdissected to a high degree of enrichment and purity. |
2014-03-18 |
2023-08-12 |
Not clear |
| Lachlan H Thompson, Clare L Paris. Transplantation of fetal midbrain dopamine progenitors into a rodent model of Parkinson's disease. Methods in molecular biology (Clifton, N.J.). vol 1059. 2014-02-25. PMID:23934843. |
transplantation of fetal midbrain dopamine progenitors into a rodent model of parkinson's disease. |
2014-02-25 |
2023-08-12 |
Not clear |
| Lachlan H Thompson, Clare L Paris. Transplantation of fetal midbrain dopamine progenitors into a rodent model of Parkinson's disease. Methods in molecular biology (Clifton, N.J.). vol 1059. 2014-02-25. PMID:23934843. |
this chapter describes the basic procedures for preparation of dopamine progenitor rich cell suspensions of ventral mesencephalon as well as implantation into the unilateral 6-hydroxydopamine model of pd and assessment of functional impact according to drug-induced rotational behavior. |
2014-02-25 |
2023-08-12 |
Not clear |
| Alan Ceaser, John G Csernansky, Deanna M Barc. COMT influences on prefrontal and striatal blood oxygenation level-dependent responses during working memory among individuals with schizophrenia, their siblings, and healthy controls. Cognitive neuropsychiatry. vol 18. issue 4. 2014-02-12. PMID:23030509. |
these effects are thought to occur through changes in dopamine signalling from the midbrain and via feedback from the frontal cortex. |
2014-02-12 |
2023-08-12 |
Not clear |
| E Hensleigh, L M Pritchar. Glucocorticoid receptor expression and sub-cellular localization in dopamine neurons of the rat midbrain. Neuroscience letters. vol 556. 2014-02-10. PMID:24121048. |
glucocorticoid receptor expression and sub-cellular localization in dopamine neurons of the rat midbrain. |
2014-02-10 |
2023-08-12 |
rat |
| Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Asheeta A Prasad, R Jeroen Pasterkamp, Maria L Macheda, Steven A Stacker, Clare L Paris. Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons. Stem cells and development. vol 22. issue 15. 2014-02-05. PMID:23517308. |
within the developing ventral midbrain (vm), wnts have been shown to contribute to the proliferation, differentiation, and connectivity of dopamine (da) neurons; however, the wnt-related receptors regulating these events remain less well described. |
2014-02-05 |
2023-08-12 |
mouse |
| Matthew Benskey, Ki Yong Lee, Kevin Parikh, Keith J Lookingland, John L Goudrea. Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein. Neurotoxicology. vol 37. 2014-02-05. PMID:23643664. |
hypothalamic tuberoinfundibular dopamine (tida) neurons remain unaffected in parkinson disease (pd) while there is significant degeneration of midbrain nigrostriatal dopamine (nsda) neurons. |
2014-02-05 |
2023-08-12 |
mouse |
| Jisook Moon, Hyun-Seob Lee, Jun Mo Kang, Junpil Park, Amanda Leung, Sunghoi Hong, Sangmi Chung, Kwang-Soo Ki. Stem cell grafting improves both motor and cognitive impairments in a genetic model of Parkinson's disease, the aphakia (ak) mouse. Cell transplantation. vol 22. issue 7. 2014-01-22. PMID:23031199. |
stem cell-based cell replacement of lost midbrain dopamine (mda) neurons is a potential therapy for parkinson's disease (pd). |
2014-01-22 |
2023-08-12 |
mouse |
| Min Yan, Maosheng Sun, Yan Zhou, Wanpu Wang, Zhanlong He, Donghong Tang, Shuaiyao Lu, Xiaonan Wang, Song Li, Wenju Wang, Hongjun L. Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopamine neurons mediated by the Lmx1a and neurturin in vitro: potential therapeutic application for Parkinson's disease in a rhesus monkey model. PloS one. vol 8. issue 5. 2014-01-10. PMID:23724014. |
recent studies provided that lmx1α play an important role in the midbrain dopamine cells differentiation. |
2014-01-10 |
2023-08-12 |
human |