| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jadwiga Jośko, Jacek Drab, Jerzy Jochem, Przemysław Nowak, Ryszard Szkilnik, Eva Korossy-Mruk, Dariusz Boroń, Richard M Kostrzewa, Halina Brus, Ryszard Bru. Ontogenetic serotoninergic lesioning alters histaminergic activity in rats in adulthood. Neurotoxicity research. vol 20. issue 2. 2011-09-30. PMID:20838952. |
at 10 week levels of 5-ht and its metabolite 5-hydroxyindole acetic acid (5-hiaa) were determined in frontal cortex, striatum, and hippocampus by an hplc/ed technique. |
2011-09-30 |
2023-08-12 |
rat |
| Makiko Kuwagata, Katsumasa Muneoka, Tetsuo Ogawa, Seiji Shiod. Effects of the genotoxic agent 5-bromo-2'-deoxyuridine with or without pre-pubertal gonadectomy on brain monoamines and their metabolites in female rats. Brain research bulletin. vol 85. issue 3-4. 2011-09-30. PMID:21414389. |
brdu-treated females showed elevations of dopamine and 5-ht levels in the striatum; reductions in dopamine, dihydroxyphenylacetic acid, or homovanillic acid (hva) in the hypothalamus or the midbrain; and elevated hva and 5-ht in the hippocampus. |
2011-09-30 |
2023-08-12 |
rat |
| J Del Pino, M A Martínez, V J Castellano, E Ramos, M R Martínez-Larrañaga, A Anadó. Effects of prenatal and postnatal exposure to amitraz on norepinephrine, serotonin and dopamine levels in brain regions of male and female rats. Toxicology. vol 287. issue 1-3. 2011-09-30. PMID:21708217. |
in contrast, amitraz did not modify 5-ht content, but caused an increase in 5-hiaa content in the medulla oblongata and hippocampus in male and female offspring. |
2011-09-30 |
2023-08-12 |
rat |
| J Del Pino, M A Martínez, V J Castellano, E Ramos, M R Martínez-Larrañaga, A Anadó. Effects of prenatal and postnatal exposure to amitraz on norepinephrine, serotonin and dopamine levels in brain regions of male and female rats. Toxicology. vol 287. issue 1-3. 2011-09-30. PMID:21708217. |
amitraz evoked increases in 5-ht turnover in the prefrontal cortex as well as in da turnover in the striatum and hippocampus but decreases in ne turnover in the hypothalamus, prefrontal cortex and striatum. |
2011-09-30 |
2023-08-12 |
rat |
| Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20800616. |
monoamine content was measured with hplc in contralateral punches from striatum and hippocampus to compare the mdma-induced loss of 5ht innervation with constituents in the (1)h-mrs profile. |
2011-09-29 |
2023-08-12 |
human |
| Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20800616. |
when assessed 7 days after the last mdma injection, levels of hippocampal and striatal serotonin (5ht) were significantly reduced, consistent with published animal studies. |
2011-09-29 |
2023-08-12 |
human |
| Shane A Perrine, Farhad Ghoddoussi, Mark S Michaels, Elisabeth M Hyde, Donald M Kuhn, Matthew P Gallowa. MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain. Neurotoxicology. vol 31. issue 6. 2011-09-29. PMID:20800616. |
however, the collective pattern of changes in 5ht, ins, glutamate and gaba is consistent with persistent hippocampal neuroadaptations caused by mdma. |
2011-09-29 |
2023-08-12 |
human |
| B Ribeiro Do Couto, M Rodríguez-Arias, S Fuentes, H Gagliano, A Armario, J Miñarro, M A Aguila. Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA. Physiology & behavior. vol 103. issue 5. 2011-09-29. PMID:21324326. |
after reinstatement, an increase in monoamine levels was observed in mice pre-exposed to etoh (da, dopac and 5-ht in the striatum and 5-hiaa in the cortex and hippocampus) or mdma (5-ht in the hippocampus). |
2011-09-29 |
2023-08-12 |
mouse |
| Rachel A Hill, Simon S Murray, Paul G Halley, Michele D Binder, Sally J Martin, Maarten van den Buus. Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087884. |
brain-derived neurotrophic factor expression is increased in the hippocampus of 5-ht(2c) receptor knockout mice. |
2011-09-28 |
2023-08-12 |
mouse |
| Rachel A Hill, Simon S Murray, Paul G Halley, Michele D Binder, Sally J Martin, Maarten van den Buus. Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087884. |
western blot analysis demonstrated a significant 2.2-fold increase in the expression of the mature form of bdnf in 5-ht(2c) ko mice when compared with wild-type controls (wt) in the hippocampus (p = 0.008), but not frontal cortex or striatum. |
2011-09-28 |
2023-08-12 |
mouse |
| Rachel A Hill, Simon S Murray, Paul G Halley, Michele D Binder, Sally J Martin, Maarten van den Buus. Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087884. |
hence, increased mature bdnf levels in 5-ht(2c) ko hippocampus are most likely due to increased extracellular cleavage rates of pro-bdnf to its mature form. |
2011-09-28 |
2023-08-12 |
mouse |
| Rachel A Hill, Simon S Murray, Paul G Halley, Michele D Binder, Sally J Martin, Maarten van den Buus. Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087884. |
in conclusion, loss of 5-ht(2c) receptor expression leads to a marked and selective increase in levels of the mature form of bdnf in the hippocampus. |
2011-09-28 |
2023-08-12 |
mouse |
| Jadwiga Jośko, Jacek Drab, Przemysław Nowak, Ryszard Szkilnik, Eva Körossy, Dariusz Boroń, Halina Brus, Richard M Kostrzewa, Ryszard Bru. Thioperamide, an H₃ receptor antagonist prevents [³H]glucose uptake in brain of adult rats lesioned as neonates with 5,7-dihydroxytryptamine. Neurotoxicity research. vol 20. issue 1. 2011-09-23. PMID:20838953. |
at 8 weeks lesioned and control rats were terminated in order to validate the effectiveness of 5,7-dht: reduction in 5-ht and 5-hiaa by 83-91% and 69-83% in striatum, frontal cortex, and hippocampus (hplc/ed method). |
2011-09-23 |
2023-08-12 |
rat |
| Masahiro Shibasaki, Kazuhiro Kurokawa, Seitaro Ohkum. [Functional homology between alcohol dependence and mood disorder]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 46. issue 3. 2011-09-22. PMID:21861331. |
moreover, 5-ht(1a) receptors in the cingulate cortex and hippocampus and 5-ht(2a) receptors in hippocampus decreased. |
2011-09-22 |
2023-08-12 |
mouse |
| Nicolas Salomé, Magdalena Taube, Emil Egecioglu, Caroline Hansson, Björn Stenström, Duan Chen, Daniel R Andersson, H Georg Kuhn, Claes Ohlsson, Suzanne L Dickso. Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21535247. |
thus, gsx induces an alteration of emotional reactivity and a memory/cognitive deficit that is associated with reduced turnover of serotonin and dopamine in the nucleus accumbens and decreased expression of egr-1 in the hippocampus and amygdala. |
2011-09-16 |
2023-08-12 |
rat |
| Qing-Qiu Mao, Yan-Fang Xian, Siu-Po Ip, Chun-Tao Ch. Involvement of serotonergic system in the antidepressant-like effect of piperine. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 4. 2011-09-13. PMID:21477634. |
in addition, the neurochemical assays showed that piperine produced a marked increase of 5-ht level in both the hippocampus and frontal cortex of mice. |
2011-09-13 |
2023-08-12 |
mouse |
| Guadalupe García-Alcocer, Angelina Rodríguez, Paulina Moreno-Layseca, Laura C Berumen, Jesica Escobar, Ricardo Miled. Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment. Neuroscience letters. vol 486. issue 3. 2011-09-06. PMID:20863873. |
in this work we studied the changes on the expression of 5-ht(5a) receptors in rat hippocampus induced by leptin, an adipocyte-derived hormone that has been reported to participate in the modulation of food intake and in adult hippocampal neurogenesis. |
2011-09-06 |
2023-08-12 |
rat |
| Guadalupe García-Alcocer, Angelina Rodríguez, Paulina Moreno-Layseca, Laura C Berumen, Jesica Escobar, Ricardo Miled. Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment. Neuroscience letters. vol 486. issue 3. 2011-09-06. PMID:20863873. |
to study the effect of leptin on the 5-ht(5a) receptor gene expression a qrt-pcr was used and the distribution of those receptors in the hippocampus was visualized by immunohistochemistry. |
2011-09-06 |
2023-08-12 |
rat |
| Guadalupe García-Alcocer, Angelina Rodríguez, Paulina Moreno-Layseca, Laura C Berumen, Jesica Escobar, Ricardo Miled. Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment. Neuroscience letters. vol 486. issue 3. 2011-09-06. PMID:20863873. |
the results showed that even though the 5-ht(5a) gene expression did not change in the hippocampus of any of the treated groups, in the rats treated with leptin and serotonin, the specific immunostaining for the 5-ht(5a) serotonin receptor decreased significantly in the dentate gyrus. |
2011-09-06 |
2023-08-12 |
rat |
| Jochen Winterer, A Vanessa Stempel, Tamar Dugladze, Csaba Földy, Nino Maziashvili, Aleksandar R Zivkovic, Josef Priller, Ivan Soltesz, Tengis Gloveli, Dietmar Schmit. Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 23. 2011-09-01. PMID:21653851. |
cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus. |
2011-09-01 |
2023-08-12 |
rat |