| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jana Tchekalarova, Daniela Pechlivanova, Tsvetomira Atanasova, Petya Markova, Valentin Lozanov, Alexander Stoyne. Diurnal variations in depression-like behavior of Wistar and spontaneously hypertensive rats in the kainate model of temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 20. issue 2. 2011-06-13. PMID:21277833. |
decreases in serotonin, tryptophan, and dopamine concentrations in the hippocampus were detected in epileptic wistar rats compared with naive controls. |
2011-06-13 |
2023-08-12 |
rat |
| Robrecht Raedt, Ralph Clinckers, Lies Mollet, Kristl Vonck, Riëm El Tahry, Tine Wyckhuys, Veerle De Herdt, Evelien Carrette, Wytse Wadman, Yvette Michotte, Ilse Smolders, Paul Boon, Alfred Meur. Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model. Journal of neurochemistry. vol 117. issue 3. 2011-06-10. PMID:21323924. |
we used in vivo intracerebral microdialysis to measure vns-induced changes in hippocampal extracellular concentrations of noradrenaline, dopamine, serotonin and gaba in freely moving, male wistar rats. |
2011-06-10 |
2023-08-12 |
rat |
| Xiaojun Wu, Hung Hsuchou, Abba J Kastin, Yi He, Reas S Khan, Kirsten P Stone, Michael S Cash, Weihong Pa. Interleukin-15 affects serotonin system and exerts antidepressive effects through IL15Rα receptor. Psychoneuroendocrinology. vol 36. issue 2. 2011-06-02. PMID:20724079. |
the hippocampus of the il15rα knockout mice had decreased mrna for 5-ht(1a), increased mrna for 5-ht(2c), and region-specific changes of serotonin reuptake transporter (sert) immunoreactivity. |
2011-06-02 |
2023-08-12 |
mouse |
| P Bloms-Funke, E Dremencov, T I F H Cremers, T M Tzschentk. Tramadol increases extracellular levels of serotonin and noradrenaline as measured by in vivo microdialysis in the ventral hippocampus of freely-moving rats. Neuroscience letters. vol 490. issue 3. 2011-06-01. PMID:21195741. |
tramadol increases extracellular levels of serotonin and noradrenaline as measured by in vivo microdialysis in the ventral hippocampus of freely-moving rats. |
2011-06-01 |
2023-08-12 |
rat |
| P Bloms-Funke, E Dremencov, T I F H Cremers, T M Tzschentk. Tramadol increases extracellular levels of serotonin and noradrenaline as measured by in vivo microdialysis in the ventral hippocampus of freely-moving rats. Neuroscience letters. vol 490. issue 3. 2011-06-01. PMID:21195741. |
the aim of the current study was to compare, using in vivo microdialysis, the effect of tramadol on extracellular serotonin (5-ht) and noradrenaline (na) levels in the rat ventral hippocampus with the effects of the dual 5-ht/na inhibitors (snris) duloxetine and venlafaxine, the tricyclic antidepressant clomipramine, the selective 5-ht re-uptake inhibitor (ssri) citalopram, and the selective na re-uptake inhibitor (nri) reboxetine. |
2011-06-01 |
2023-08-12 |
rat |
| Kornélia Tekes, P Szegi, R Laufer, M Hantos, G Csab. Effect of perinatal stress on the biogenic amine neurotransmitter level of the adult rat's brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 29. issue 2. 2011-05-31. PMID:21126566. |
the amount of biogenic amines (dopamine and serotonin) and their metabolites (dopac, hva, 5-hiaa, and 5-htol) in five regions of the brain (frontal cortex, hypothalamus, hippocampus, striatum, and brainstem) was studied in the male and female offspring of control and perinatally (48 h before birth or 48 h after birth) food and water deprived dams, when they were three months old, by using hplc-ec determination. |
2011-05-31 |
2023-08-12 |
rat |
| S Nullmeier, P Panther, H Dobrowolny, M Frotscher, S Zhao, H Schwegler, R Wol. Region-specific alteration of GABAergic markers in the brain of heterozygous reeler mice. The European journal of neuroscience. vol 33. issue 4. 2011-05-31. PMID:21226776. |
in the present study using immunocytochemical procedures, we investigated hrm and wild-type mice (wt) for differences in the numbers and densities of glutamic acid decarboxylase (gad)67 and parvalbumin (parv)-immunoreactive (ir) neurons in the hippocampus, tyrosine hydroxylase (th)-ir neurons in the ventral tegmental area (vta) and substantia nigra (sn), and serotonin transporter (5-ht-t)-ir neurons of the raphe nuclei. |
2011-05-31 |
2023-08-12 |
mouse |
| Emily Freeman-Daniels, Sheryl G Beck, Lynn G Kirb. Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20981413. |
tissue-specific "rescue" strategies and electrophysiology have implicated a critical role for postsynaptic 5-ht(1a) receptors, particularly in the ca1 region of the hippocampus. |
2011-05-24 |
2023-08-12 |
mouse |
| Nicola D Hanson, Charles B Nemeroff, Michael J Owen. Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus. The Journal of pharmacology and experimental therapeutics. vol 337. issue 1. 2011-05-19. PMID:21220416. |
we found no effect of the selective serotonin reuptake inhibitor fluoxetine or the corticotropin-releasing factor receptor 1 antagonist r121919 [3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-n,n-dipropyl-1h-pyrazolo[1,5-a]pyrimidin-8-ium-7-amine] on the rate of cell proliferation or hippocampal brain-derived neurotrophic factor (bdnf) mrna expression in either adult or adolescent rats after long-term administration. |
2011-05-19 |
2023-08-12 |
rat |
| Debapriya Garabadu, Ankit Shah, Ausaf Ahmad, Vijaya B Joshi, Bhagawati Saxena, Gautam Palit, Sairam Krishnamurth. Eugenol as an anti-stress agent: modulation of hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in a rat model of stress. Stress (Amsterdam, Netherlands). vol 14. issue 2. 2011-05-16. PMID:21034296. |
eugenol also reversed the stress-induced changes in 5-ht levels in all brain regions, whereas ne levels were reversed in all brain regions except hippocampus. |
2011-05-16 |
2023-08-12 |
rat |
| Caroline A Browne, Gerard Clarke, Timothy G Dinan, John F Crya. Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21130784. |
in contrast, balb/c mice exhibit significant increases in 5-ht turnover in the striatum and hippocampus only following repeated stress. |
2011-05-12 |
2023-08-12 |
mouse |
| Masaaki Kanai, Hiroshi Funakoshi, Hisaaki Takahashi, Tomoko Hayakawa, Shinya Mizuno, Kunio Matsumoto, Toshikazu Nakamur. Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice. Molecular brain. vol 2. 2011-05-02. PMID:19323847. |
compared with wild-type littermates, tdo(-/-) mice showed increased plasma levels of trp and its metabolites 5-hydroxyindoleacetic acid (5-hiaa) and kynurenine, as well as increased levels of trp, 5-ht and 5-hiaa in the hippocampus and midbrain. |
2011-05-02 |
2023-08-12 |
mouse |
| Cliona M O'Mahony, Gerard Clarke, Sinead Gibney, Timothy G Dinan, John F Crya. Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression. Pharmacology, biochemistry, and behavior. vol 97. issue 4. 2011-04-25. PMID:21110995. |
wky animals showed similar stress-induced decreases in hippocampal gaba, noradrenaline and dopamine as their sd counterparts while exhibiting a divergent decrease in 5-ht, 5-hiaa and dopac. |
2011-04-25 |
2023-08-12 |
rat |
| Susana Esteban, Celia Garau, Sara Aparicio, David Moranta, Pere Barceló, Margarita Ramis, Jesús A F Tresguerres, Rubén Ria. Improving effects of long-term growth hormone treatment on monoaminergic neurotransmission and related behavioral tests in aged rats. Rejuvenation research. vol 13. issue 6. 2011-04-22. PMID:21208059. |
also, the content of the neurotransmitters serotonin, dopamine, and noradrenaline and some metabolites was measured by high-pressure liquid chromatography (hplc) in the hippocampus and striatum, brain regions involved in adult memory processing and motor coordination. |
2011-04-22 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
hippocampal serotonin depletion facilitates place learning concurrent with an increase in ca1 high frequency theta activity expression in the rat. |
2011-04-18 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
however, several studies have shown that serotonin tends to desynchronise hippocampal eeg activity. |
2011-04-18 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
for these reasons, we investigated the possible role of hippocampal serotonin in the regulation of theta activity during the acquisition of map-based spatial information. |
2011-04-18 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
following 5-ht hippocampal depletion through 5,7-dihydroxytriptamine-induced lesions to the fimbria, fornix and cingulate bundle of adult rats, ca1 hippocampal theta activity was recorded during place learning training. |
2011-04-18 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
a facilitation of place learning after hippocampal serotonin depletion occurred, and was associated with earlier expression of dominant high frequency theta activity (6.5-9.5hz). |
2011-04-18 |
2023-08-12 |
rat |
| Anders Ettrup, Birgitte R Kornum, Pia Weikop, Gitte M Knudse. An approach for serotonin depletion in pigs: effects on serotonin receptor binding. Synapse (New York, N.Y.). vol 65. issue 2. 2011-04-01. PMID:20560131. |
on day 5, tissue concentrations of 5-ht in seven distinct brain structures from one hemisphere: frontal and occipital cortex, striatum, hippocampus, cerebellum, rostral, and caudal brain stem, were determined. |
2011-04-01 |
2023-08-12 |
human |