| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lili Zou, Yaling Tian, Yuanfei Wang, Dongliang Chen, Xiaomin Lu, Ze Zeng, Zumin Chen, Chenli Lin, Yinji Lian. High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation. Journal of affective disorders. 2023-02-04. PMID:36738999. |
further, pearson correlation analysis showed that akkermansia_muciniphila was significantly negatively correlated with the concentration of mcp-1, il-17a in serum and 5-ht in hippocampal. |
2023-02-04 |
2023-08-14 |
mouse |
| Laura C Fox, Jamie L Scholl, Michael J Watt, Gina L Forste. GABA Neuroscience. 2023-02-03. PMID:36736883. |
the hippocampus and amygdala are implicated in stress responses and anxiety, and within these regions, gamma-aminobutyric acid (gaba) and serotonin modulate output and behavioral expression. |
2023-02-03 |
2023-08-14 |
Not clear |
| Mareli Roets, Linda Brand, Stephan F Stey. Increased depressive-like behaviour of postpartum Flinders sensitive and resistant line rats is reversed by a predictable postpartum stressor. Behavioural brain research. 2023-01-31. PMID:36720349. |
regardless of strain, pregnancy decreased time spent in the open arms of the elevated plus maze and hippocampal serotonin concentrations. |
2023-01-31 |
2023-08-14 |
rat |
| Mareli Roets, Linda Brand, Stephan F Stey. Increased depressive-like behaviour of postpartum Flinders sensitive and resistant line rats is reversed by a predictable postpartum stressor. Behavioural brain research. 2023-01-31. PMID:36720349. |
msew reversed these behaviours in both strains and increased social interaction with a male counterpart in the fsl rats, without influencing hippocampal or cortical serotonin or norepinephrine. |
2023-01-31 |
2023-08-14 |
rat |
| Nan Nan, Qi Wang, Mei-Jing Li, Yong-Song Xu, Xiao-Meng Guo, Rui Xu, Zhe Ma, Si-Hui Wang, Jing Li, Hui Zhao, Mu-Xin Gon. The Microbiota-Dependent Treatment of Wuzhuyu Decoction for Chronic Migraine Model Rat Associated with Anxiety-Depression Like Behavior. Oxidative medicine and cellular longevity. vol 2023. 2023-01-17. PMID:36647428. |
the cm rats exhibited anxiety- and depression-like behavior with 5-ht and number of neurons decreased in the ca1 and ca2 regions of hippocampal. |
2023-01-17 |
2023-08-14 |
rat |
| Pan Meng, Xi Zhang, Dandan Li, Hui Yang, Xiaoyuan Lin, Hongqing Zhao, Ping Li, Yuhong Wang, Xiaoye Wang, Jinwen G. Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis. Neural plasticity. vol 2023. 2023-01-17. PMID:36647544. |
western blot was utilized to measure the expression of bdnf and 5-ht in the hippocampus. |
2023-01-17 |
2023-08-14 |
rat |
| Kristi Liiver, Sophie Imbeault, Marianna Školnaja, Tanel Kaart, Margus Kanarik, Karita Laugus, Jade De Wettinck, Aleksander Pulver, Ruth Shimmo, Jaanus Harr. Active vs passive novelty-related strategies: Sex differences in exploratory behaviour and monoaminergic systems. Behavioural brain research. 2023-01-14. PMID:36641084. |
male rats had lower levels of dopamine (da) in frontal cortex, and higher levels of 3,4-dihydroxyphenylacetic acid (dopac) in raphe area; higher levels of serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in dorsal striatum but lower levels of 5-ht and 5-hiaa in locus coeruleus area, 5-hiaa levels were also lower in hippocampus as compared to females. |
2023-01-14 |
2023-08-14 |
rat |
| . Expression of Concern: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 18. issue 1. 2023-01-11. PMID:36630395. |
expression of concern: t-type calcium channel enhancer sak3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. |
2023-01-11 |
2023-08-14 |
mouse |
| P D Komleva, E Yu Bazhenova, N V Khotskin, E A Kulikova, A V Kuliko. C1473G Polymorphism in Tph2 Gene Affects Activation of Serotonin Metabolism in Mouse Brain 24 h after LPS Administration. Bulletin of experimental biology and medicine. 2023-01-04. PMID:36600037. |
we studied the effect of the c1473g polymorphism in the tph2 gene that reduces the activity of the tryptophan hydroxylase 2 in the brain on the severity of changes in motor activity (23 h after intraperitoneal administration of 0.8 mg/kg lps or saline) and on the level of serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the endings of 5-ht neurons in the cortex, hippocampus, and striatum (24 h after administration) of mature male mice of congenic lines b6-1473cc (high activity) and b6-1473gg (low activity). |
2023-01-04 |
2023-08-14 |
mouse |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Parisa Ghanbari, Sanaz Khajehzadeh, Asieh Sayyed, Davood Raeisi, Omidreza Saleh. The effect of high intensity interval training with beetroot (Beta vulgaris) juice supplementation on serotonin and dopamine receptors expression, anxiety and depression in middle-aged diabetic rats. Avicenna journal of phytomedicine. vol 12. issue 6. 2022-12-30. PMID:36583177. |
the aim of this study was to evaluate the effect of four weeks of high intensity interval training (hiit) with beetroot juice supplementation (bj) on serotonin and dopamine receptors in hippocampal tissue, as well as anxiety and depression in middle-aged diabetic rats. |
2022-12-30 |
2023-08-14 |
rat |
| Jamie L Scholl, Rajeshwari R Solanki, Michael J Watt, Kenneth J Renner, Gina L Forste. Chronic administration of glucocorticoid receptor ligands increases anxiety-like behavior and selectively increase serotonin transporters in the ventral hippocampus. Brain research. 2022-12-03. PMID:36462646. |
chronic administration of glucocorticoid receptor ligands increases anxiety-like behavior and selectively increase serotonin transporters in the ventral hippocampus. |
2022-12-03 |
2023-08-14 |
rat |
| Jamie L Scholl, Rajeshwari R Solanki, Michael J Watt, Kenneth J Renner, Gina L Forste. Chronic administration of glucocorticoid receptor ligands increases anxiety-like behavior and selectively increase serotonin transporters in the ventral hippocampus. Brain research. 2022-12-03. PMID:36462646. |
interestingly, treatment with mifepristone alone reduced plasma corticosterone levels and increased serotonin transporter and gr expression in the ventral hippocampus but did not significantly affect oct3 expression or behavior. |
2022-12-03 |
2023-08-14 |
rat |
| Jamie L Scholl, Rajeshwari R Solanki, Michael J Watt, Kenneth J Renner, Gina L Forste. Chronic administration of glucocorticoid receptor ligands increases anxiety-like behavior and selectively increase serotonin transporters in the ventral hippocampus. Brain research. 2022-12-03. PMID:36462646. |
no treatment effects on oct3, serotonin transporter or gr expression were observed in the dmh, cea or dorsal hippocampus. |
2022-12-03 |
2023-08-14 |
rat |
| Ling Yang, Tung-Hu Tsa. Neuroprotective effect and herbal-drug pharmacokinetic interaction of Gastrodia elata extract on valproic acid. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-11-22. PMID:36411625. |
in addition, g. elata extract and vpa exerted synergistic anticonvulsive effects to decrease the seizure severity by protecting neurons in the hippocampus and altering the dopac and 5-ht levels. |
2022-11-22 |
2023-08-14 |
rat |
| Satya Kumar Avula, Ajmal Khan, Sobia Ahsan Halim, Najeeb Ur Rehman, Nasiara Karim, Imran Khan, Rene Csuk, Biswanath Das, Ahmed Al-Harras. Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi- incensole acetate in chronic unpredictable mild stress model of depression; behavioural and biochemical correlates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-11-22. PMID:36411640. |
the tested compounds also inhibited monoamine oxidase-a (mao) enzyme and increased the levels of brain noradrenaline (na) and 5-hydroxytryptamine (5-ht), decreased plasma corticosterone and pro-inflammatory cytokines including tnf-α, il-6 in hippocampal homogenates. |
2022-11-22 |
2023-08-14 |
mouse |
| Cai Zhang, Baiping Liu, Jodi Pawluski, Harry W M Steinbusch, U Kirthana Kunikullaya, Cai Son. The effect of chronic stress on behaviors, inflammation and lymphocyte subtypes in male and female rats. Behavioural brain research. 2022-11-22. PMID:36414104. |
results show that cums increased anhedonia and anxiety-like behaviors, along with increased serum corticosterone, hippocampal pro-inflammatory factors, cd11b, ifn-γ, il-6 and il-17, but decreased cd4, cd25, cd4/cd8 ratio, gfap, 5-hydroxytryptamine (5-ht) and ne concentrations, regardless of sex. |
2022-11-22 |
2023-08-14 |
rat |
| Ahmed I Foudah, Mohammed H Alqarni, Aftab Alam, Sushma Devi, Mohammad A Salkini, Prawez Ala. Rutin Improves Anxiety and Reserpine-Induced Depression in Rats. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364141. |
this effect was mediated by increased serotonin, norepinephrine, and dopamine levels in cortical and hippocampal regions. |
2022-11-11 |
2023-08-14 |
rat |
| Niklas Reich, Christian Hölsche. Beyond Appetite: Acylated Ghrelin As A Learning, Memory and Fear Behavior-modulating Hormone. Neuroscience and biobehavioral reviews. 2022-11-11. PMID:36368526. |
as such, in this review, we i) evaluate what specific stages and forms of memory, as well as which respective brain areas are affected by acylated ghrelin, ii) illustrate the plasticity-associated signaling pathways of ag in the hippocampus, also involving memory resolution-enhancing neurogenesis, iii) elucidate how the peptide modulates neurotransmitter systems (glutamate, γ-aminobutyric acid, dopamine, serotonin), iv) clarify the role of ag in conditioned taste aversion, novelty learning and the formation of spatial, recognition, auditory fear, contextual fear and passive avoidance memories in the hippocampus and amygdala as well as v) solve the mystery behind ag, its impact on the 5-ht system, the recently established link to post-traumatic stress disorder and the either fear-suppressing or fear-potentiating effects under neutral and acutely stressed conditions or chronic stress, respectively. |
2022-11-11 |
2023-08-14 |
Not clear |
| Benneth Ben-Azu, Christian I Uruaka, Abayomi M Ajayi, Thiophilus Aghogho Jarikre, Kingsley E Nwangwa, Kingsley C Chilaka, Bienose S Chijioke, Marymagdalene G Omonyeme, Chineye B Ozege, Emmanuella C Ofili, Ebidenara B Warekoromor, Nwanneka L Edigbue, Ufoma V Esiekpe, Dabrechi E Akaenyi, Gladys O Ag. Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice. Neurochemical research. 2022-11-09. PMID:36350433. |
taurine reduced ketamine-induced dopamine and 5-hydroxytryptamine changes, and increased gad and bdnf levels in the striatum, prefrontal-cortex and hippocampus, suggesting increased gabaergic and neurotrophic transmissions. |
2022-11-09 |
2023-08-14 |
mouse |