| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D V Sherbakov, A B Arefieva, P D Komleva, A E Iz'urov, N V Khotskin, D V Bazovkina, A V Kuliko. [Alterations in the Level of mRNA of TPH1, TPH2 Genes, Tryptophan Hydroxylase Activity and Serotonin Metabolism in Mouse Brain Five Days after Lipopolysaccharide Administration]. Molekuliarnaia biologiia. vol 57. issue 2. 2023-03-31. PMID:37000657. |
the highest concentration of tph2 gene mrna was observed in the midbrain in 5-ht neuron bodies, while this gene mrna level was lower in 5-ht endings (cortex, hippocampus, striatum, and hypothalamus). |
2023-03-31 |
2023-08-14 |
mouse |
| Yingyu Zhang, Yuan Sun, Yupei Liu, Jiameng Liu, Jing Sun, Xinmin Liu, Bei Fan, Cong Lu, Fengzhong Wan. Polygonum sibiricum polysaccharides exert the antidepressant-like effects in chronic unpredictable mild stress-induced depressive mice by modulating microbiota-gut-brain axis. Phytotherapy research : PTR. 2023-03-30. PMID:36996849. |
fmt significantly increased the levels of 5-hydroxytryptamine and norepinephrine, decreased the levels of the pro-inflammatory cytokines in the hippocampus and reduced the levels of corticosterone, an adrenocorticotropic-hormone, in the serum of cums-induced mice. |
2023-03-30 |
2023-08-14 |
mouse |
| Xiaoju Liu, Haijuan Wang, Xiaoyu Wang, Yinxia Ning, Wei Liu, Jie Ga. Baixiangdan capsule and Shuyu capsule regulate anger-out and anger-in, respectively: GB1-mediated GABA can regulate 5-HT levels in multiple brain regions. Aging. vol 15. 2023-03-29. PMID:36988497. |
the improvement way is as follows: decreased abnormal increase of gaba and gb1 in the drn further mediated synaptic inhibition and increased 5-ht level in the drn, leading to increased 5-ht levels in the pfc, hypothalamus, and hippocampus. |
2023-03-29 |
2023-08-14 |
rat |
| Elisa Castagnola, Elaine M Robbins, Daniela D Krahe, Bingchen Wu, May Yoon Pwint, Qun Cao, Xinyan Tracy Cu. Stable in-vivo electrochemical sensing of tonic serotonin levels using PEDOT/CNT-coated glassy carbon flexible microelectrode arrays. Biosensors & bioelectronics. vol 230. 2023-03-29. PMID:36989659. |
in vivo, our pedot/cnt-coated gc meas successfully detected basal 5-ht concentrations at different locations within the ca2 region of the hippocampus of both anesthetized and awake mice. |
2023-03-29 |
2023-08-14 |
mouse |
| Elisa Castagnola, Elaine M Robbins, Daniela D Krahe, Bingchen Wu, May Yoon Pwint, Qun Cao, Xinyan Tracy Cu. Stable in-vivo electrochemical sensing of tonic serotonin levels using PEDOT/CNT-coated glassy carbon flexible microelectrode arrays. Biosensors & bioelectronics. vol 230. 2023-03-29. PMID:36989659. |
furthermore, the pedot/cnt-coated meas were able to detect tonic 5-ht in the mouse hippocampus for one week after implantation. |
2023-03-29 |
2023-08-14 |
mouse |
| Guanlan Liu, Israr Khan, Yuxi Li, Yun Yang, Xuerui Lu, Yafei Wang, Junxiang Li, Chunjiang Zhan. Overcoming Anxiety Disorder by Probiotic Foods (Basel, Switzerland). vol 11. issue 22. 2023-03-08. PMID:36429192. |
lzu-j-tsl6 was able to effectively increase the gaba content in the mice hippocampus (p < 0.0001) and restore some markers related to anxiety such as brain-derived neurotrophic factor (bdnf), glial fibrillary acidic protein (gfap), and 5-hydroxytryptamine (5-ht). |
2023-03-08 |
2023-08-16 |
mouse |
| Bao Gong, Can-Hong Wang, Yu-Lan Wu, Yang-Yang Liu, Jian-He We. [Anxiolytic and antidepressant effects of agarwood inhalation and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 4. 2023-03-05. PMID:36872273. |
the enzyme-linked immunosorbent assay(elisa) was used to determine the levels of 5-hydroxytryptamine(5-ht), glutamic acid(glu), and γ-aminobutyric acid(gaba_a) in the hippocampal area. |
2023-03-05 |
2023-08-14 |
rat |
| Yuqiu Yang, Yufeng Gao, Chelimoge Wan. [Mongolian medicine Heisuga-25 promotes the expression of neuroskeletal protein, increases the content of neurotransmitter and improves the symptoms of Alzheimer's disease in mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 2. 2023-03-05. PMID:36872434. |
elisa was used to detect the contents of acetylcholine (ach), 5-hydroxytryptamine (5-ht), norepinephrine (ne) and dopamine (da) in cortex and hippocampus of mice. |
2023-03-05 |
2023-08-14 |
mouse |
| Yuqiu Yang, Yufeng Gao, Chelimoge Wan. [Mongolian medicine Heisuga-25 promotes the expression of neuroskeletal protein, increases the content of neurotransmitter and improves the symptoms of Alzheimer's disease in mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 2. 2023-03-05. PMID:36872434. |
compared with the blank control group, the contents of ach, ne, da and 5-ht in hippocampus and cortex were decreased in the model group. |
2023-03-05 |
2023-08-14 |
mouse |
| Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. |
we exposed female rats to the aba paradigm and measured the levels of da, 5-ht, and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 5-hydroxyindoleacetic acid (5-hiaa), and dopaminergic type 2 (d2) receptors density in feeding- and reward-implicated brain regions (i.e., cerebral cortex, cx; prefrontal cortex, pfc; caudate putamen, cpu; nucleus accumbens, nacc; amygdala, amy; hypothalamus, hyp; hippocampus, hipp). |
2023-03-02 |
2023-08-14 |
rat |
| Elisa Giunti, Roberto Collu, Simona Dedoni, M Paola Castelli, Maria Scherma, Paola Fadd. Food restriction and hyperactivity induce changes in corticolimbic brain dopamine and serotonin levels in female rats. Behavioural brain research. 2023-03-02. PMID:36863461. |
da levels were significantly increased in the cx, pfc and nacc, while 5-ht was significantly enhanced in the nacc and hipp of aba rats. |
2023-03-02 |
2023-08-14 |
rat |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences. vol 10. issue 2. 2023-02-28. PMID:36851426. |
a staggering amount of research is suggesting that the common denominators in the pathophysiology of depression and the behavior changes in hypothyroidism are the hippocampal complex and the distorted serotonin metabolism. |
2023-02-28 |
2023-08-14 |
rat |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences. vol 10. issue 2. 2023-02-28. PMID:36851426. |
current results are promising and may serve as groundwork for further investigation of functional and structural changes in the hippocampus during a hypothyroid state, and in particular, the effects of serotonin mediation in hypothyroid-associated depressive-like behavior. |
2023-02-28 |
2023-08-14 |
rat |
| M Maetzi Estévez-Cabrera, Fausto Sánchez-Muñoz, Gilberto Pérez-Sánchez, Lenin Pavón, Adrian Hernández-Díazcouder, J Luis Córtes Altamirano, C Soria-Fregoso, Alfonso Alfaro-Rodríguez, Herlinda Bonilla-Jaim. Therapeutic treatment with fluoxetine using the chronic unpredictable stress model induces changes in neurotransmitters and circulating miRNAs in extracellular vesicles. Heliyon. vol 9. issue 2. 2023-02-28. PMID:36852042. |
after cums, the rats performed the fst, and serum levels of cort and six micrornas (mir-16, -21, -144, -155, -146a, -223) were analyzed, as were levels of dopamine, noradrenaline, and serotonin in the prefrontal cortex, hippocampus, and hypothalamus. |
2023-02-28 |
2023-08-14 |
rat |
| Paulina Surowka, Karolina Noworyta, Irena Smaga, Malgorzata Filip, Rafal Rygul. Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT Frontiers in molecular neuroscience. vol 16. 2023-02-27. PMID:36846570. |
as serotonin has been identified as an important modulator of sensitivity to feedback and because the hippocampus has been implicated in the mediation of learning from positive and negative outcomes, the present study aimed to identify differences in the expression of various genes encoding 5-ht receptors in this brain region between the rats displaying trait sensitivity and insensitivity to negative feedback. |
2023-02-27 |
2023-08-14 |
rat |
| Min-Kyung Joo, Xiaoyang Ma, Jong-Wook Yoo, Yoon-Jung Shin, Hyo-Jong Kim, Dong-Hyun Ki. Patient-derived Enterococcus mundtii and its capsular polysaccharides cause depression through the downregulation of NF-κB-involved serotonin and BDNF expression. Microbes and infection. 2023-02-09. PMID:36758891. |
nk1516 also caused the most potent depression-like behaviors in the absence of sickness behaviors, neuroinflammation, downregulated brain-derived neurotrophic factor (bdnf), and serotonin (5-ht) levels in the hippocampus of mice. |
2023-02-09 |
2023-08-14 |
mouse |
| Min-Kyung Joo, Xiaoyang Ma, Jong-Wook Yoo, Yoon-Jung Shin, Hyo-Jong Kim, Dong-Hyun Ki. Patient-derived Enterococcus mundtii and its capsular polysaccharides cause depression through the downregulation of NF-κB-involved serotonin and BDNF expression. Microbes and infection. 2023-02-09. PMID:36758891. |
its capsular polysaccharide (cp), but not cytoplasmic components, also caused depression-like behaviors and reduced bdnf and serotonin levels in the hippocampus. |
2023-02-09 |
2023-08-14 |
mouse |
| Subin Mao, Catherine Fonder, Md Fazlay Rubby, Gregory J Phillips, Donald S Sakaguchi, Long Qu. An integrated microfluidic chip for studying the effects of neurotransmitters on neurospheroids. Lab on a chip. 2023-02-08. PMID:36751868. |
to improve our understanding of how the central nervous system functions in health and disease, we report the development of an integrated chip for studying the effects of the neurotransmitters dopamine and serotonin on adult rat hippocampal progenitor cell (ahpc) neurospheroids. |
2023-02-08 |
2023-08-14 |
rat |
| Simin Afshar, Siamak Shahidi, Hemen Baooshi, Mahdieh Hoseini, Mahsa Esmaeili, Nasrin Hashemi-Firouzi, Alireza Komak. The role of hippocampal 5-HT Naunyn-Schmiedeberg's archives of pharmacology. 2023-02-07. PMID:36749399. |
the role of hippocampal 5-ht serotonin is a neurotransmitter, which is involved in memory via its receptors. |
2023-02-07 |
2023-08-14 |
Not clear |
| Lili Zou, Yaling Tian, Yuanfei Wang, Dongliang Chen, Xiaomin Lu, Ze Zeng, Zumin Chen, Chenli Lin, Yinji Lian. High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation. Journal of affective disorders. 2023-02-04. PMID:36738999. |
the concentration of 5-ht increased in the hippocampus, meanwhile, the expression of 5-ht receptor htr2a was distinct in different regions of the brain tissue. |
2023-02-04 |
2023-08-14 |
mouse |