| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shufang Xia, Gusonghan Maitiniyazi, Yuan Liu, Yue Chen, Mengting Guo, Jianyun He, Wei Tao, Ziyuan L. Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor. Food research international (Ottawa, Ont.). vol 169. 2023-05-31. PMID:37254425. |
moreover, wpi promoted the hippocampal trp, 5-hydroxytryptophan (5-htp), 5-ht, 5-hydroxyindoleacetic acid (5-hiaa) levels and inhibited kynurenine (kyn) through up-regulating serotonin transporter (sert) and down-regulating indoleamine 2, 3-dioxygenase (ido). |
2023-05-31 |
2023-08-14 |
mouse |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
they also showed significant decreases in the levels of l-tyrosine, norepinephrine, vanillylmandelic acid, 5-hydroxytryptamine, and acetylcholine, in contrast to significant increases in 5-hydroxyindoleacetic acid, l-histidine, l-glutamine, and l-arginine in the hippocampus. |
2023-05-31 |
2023-08-14 |
mouse |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
moreover, the expression of the alpha 1a adrenergic receptor (adra1a), serotonin 1 a receptor (5ht1a), and γ-aminobutyric acid a receptor subunit alpha-2 (gabra2) was significantly downregulated in the hippocampus of 3×tg-ad mice, while histamine h3 receptor (h3r) expression was significantly upregulated. |
2023-05-31 |
2023-08-14 |
mouse |
| Amine Bahi, Jean-Luc Dreye. Anxiety and Ethanol Consumption in Socially Defeated Mice; Effect of Hippocampal Serotonin Transporter Knockdown. Behavioural brain research. 2023-05-27. PMID:37244437. |
anxiety and ethanol consumption in socially defeated mice; effect of hippocampal serotonin transporter knockdown. |
2023-05-27 |
2023-08-14 |
mouse |
| Hiromi Shiozaki, Nahoko Kuga, Tasuku Kayama, Yuji Ikegaya, Takuya Sasak. Selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. Journal of pharmacological sciences. vol 152. issue 2. 2023-05-11. PMID:37169478. |
selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. |
2023-05-11 |
2023-08-14 |
Not clear |
| Hiromi Shiozaki, Nahoko Kuga, Tasuku Kayama, Yuji Ikegaya, Takuya Sasak. Selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus. Journal of pharmacological sciences. vol 152. issue 2. 2023-05-11. PMID:37169478. |
administration of the selective serotonin reuptake inhibitors (ssris) fluoxetine and fluvoxamine inhibited the generation of ventral hippocampal swrs and reduced locomotor activity and local field potential power in the gamma bands. |
2023-05-11 |
2023-08-14 |
Not clear |
| Wenyan Xian, Yu Deng, Yuzhe Yang, Zhaolun Tan, Chunlian Chen, Wu Li, Ruili Yan. Ameliorative Effect of Ellagic Acid on Aging in Rats with the Potential Mechanism Relying on the Gut Microbiota and Urolithin A-Producing Ability. Journal of agricultural and food chemistry. 2023-05-03. PMID:37132992. |
our results showed that ea improved cognitive impairment and hippocampal damage, increased the gaba (by 107.84-117.86%) and 5-ht (by 72.56-100.85%) levels, and suppressed the inflammatory and oxidative stress in aging rats. |
2023-05-03 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
5ht1ar-fgfr1 heteroreceptor complexes differently modulate girk currents in the dorsal hippocampus and the dorsal raphe serotonin nucleus of control rats and of a genetic rat model of depression. |
2023-04-28 |
2023-08-14 |
rat |
| Patrizia Ambrogini, Davide Lattanzi, Marica Pagliarini, Michael Di Palma, Stefano Sartini, Riccardo Cuppini, Kjell Fuxe, Dasiel Oscar Borroto-Escuel. 5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108630. |
the midbrain raphe serotonin (5ht) neurons provide the main ascending serotonergic projection to the forebrain, including hippocampus, which has a role in the pathophysiology of depressive disorder. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
we examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of neurotransmitters, including dopamine, serotonin, glutamate, glutamine, and gaba in the amygdala and hippocampus. |
2023-04-28 |
2023-08-14 |
rat |
| Alaa M Hammad, Ala A Alhusban, Lujain F Alzaghari, Fawaz Alasmari, Youssef Sar. Effect of Cigarette Smoke Exposure and Aspirin Treatment on Neurotransmitters' Tissue Content in Rats' Hippocampus and Amygdala. Metabolites. vol 13. issue 4. 2023-04-28. PMID:37110173. |
dopamine, serotonin, glutamate, glutamine, and gaba were extracted from both the amygdala and hippocampus and were separated and quantified using a developed and validated hplc-ms/ms method. |
2023-04-28 |
2023-08-14 |
rat |
| Daniil Grinchii, Lubica Lacinova, Eliyahu Dremenco. Effects of the acute administration of delta-opioid receptor ligands on the excitability of rat hippocampal glutamate and brainstem monoamine neurons in vivo. General physiology and biophysics. vol 42. issue 3. 2023-04-26. PMID:37098742. |
the present study aimed to investigate the acute effects of these ligands on the firing activity of hippocampal cornu ammonis 1/3 (ca1/3) glutamate, dorsal raphe nucleus (drn) serotonin (5-ht), locus coeruleus (lc) noradrenaline, and ventral tegmental area (vta) dopamine neurons in in vivo conditions. |
2023-04-26 |
2023-08-14 |
rat |
| Sijie Chen, Longsheng Huang, Guihua Liu, Jie Kang, Qinfang Qian, Jingrong Wang, Rong Wang, Lizhen Zheng, Haijun Wang, Ping O. Acupuncture Ameliorated Behavioral Abnormalities in the Autism Rat Model via Pathways for Hippocampal Serotonin. Neuropsychiatric disease and treatment. vol 19. 2023-04-25. PMID:37096024. |
acupuncture ameliorated behavioral abnormalities in the autism rat model via pathways for hippocampal serotonin. |
2023-04-25 |
2023-08-14 |
rat |
| Hongyue Wang, Jinping Hu, Jiahuan Hu, Qiuyu Chen, Nianying Shang, Mengyao Liu, Xinnan Li, Longgang Xiang, Dali Yin, Jiaqi Lan, Qiong Xiao, Ying Pen. Antidepressant effect of 4-Butyl-a-agarofuran via HPA axis and serotonin system. Brain research bulletin. 2023-04-19. PMID:37076049. |
furthermore, af-5 reduced adrenocorticotropic hormone (acth) level in serum and normalized the neurotransmitter changes, including the decreased serotonin (5-ht) in hippocampus of cums rats. |
2023-04-19 |
2023-08-14 |
mouse |
| Darya V Bazovkina, Dariya V Fursenko, Vladimir S Naumenko, Aleksandr V Kuliko. The Role of C1473G Polymorphism in Mouse Triptophan Hydroxylase 2 Gene in the Acute Effects of Ethanol on the c-fos Gene Expression and Metabolism of Biogenic Amines in the Brain. Biochemistry. Biokhimiia. vol 88. issue 3. 2023-04-19. PMID:37076278. |
acute alcoholization led to a significant upregulation of the c-fos gene expression in the frontal cortex and striatum of b6-1473g mice and in the hippocampus of b6-1473c mice and caused a decrease in the index of serotonin metabolism in the nucleus accumbens in b6-1473c mice and in the hippocampus and striatum of b6-1473g mice, as well as to the decrease in the norepinephrine level in the hypothalamus of b6-1473c mice. |
2023-04-19 |
2023-08-14 |
mouse |
| Jing Tian, Chase Stucky, Tienju Wang, Nancy A Muma, Michael Johnson, Heng D. Mitochondrial Dysfunction Links to Impaired Hippocampal Serotonin Release in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-04-17. PMID:37066917. |
mitochondrial dysfunction links to impaired hippocampal serotonin release in a mouse model of alzheimer's disease. |
2023-04-17 |
2023-08-14 |
mouse |
| Colby E Witt, Sergio Mena, Jordan Holmes, Melinda Hersey, Anna Marie Buchanan, Brenna Parke, Rachel Saylor, Lauren E Honan, Shane N Berger, Sara Lumbreras, Frederik H Nijhout, Michael C Reed, Janet Best, James Fadel, Patrick Schloss, Thorsten Lau, Parastoo Hashem. Serotonin is a Common Thread Linking Different Classes of Antidepressants. Research square. 2023-04-10. PMID:37034599. |
we measure hippocampal serotonin in mice with voltammetry and study the effects of acute challenges of antidepressants. |
2023-04-10 |
2023-08-14 |
mouse |
| Ana Carolina Dutra-Tavares, Anderson Ribeiro-Carvalho, Fernanda Nunes, Ulisses Cesar Araújo, Vitor Bruno, Tania Marcourakis, Claudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaç. Lifetime caffeine and adolescent nicotine exposure in mice: effects on anxiety-like behavior and reward. Journal of developmental origins of health and disease. 2023-04-03. PMID:37009674. |
frontal cerebral cortex dopamine content, dopamine turnover, and norepinephrine levels, as well as hippocampal serotonin 1a receptor expression were assessed. |
2023-04-03 |
2023-08-14 |
mouse |
| Kanza M Khan, Nagalakshmi Balasubramanian, Gabriel Gaudencio, Ruixiang Wang, Govindhasamy Pushpavathi Selvakumar, Louis Kolling, Samantha Pierson, Satya M Tadinada, Ted Abel, Marco Hefti, Catherine A Marcinkiewc. Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease. Acta neuropathologica communications. vol 11. issue 1. 2023-04-03. PMID:37009893. |
loss of 5-ht innervation to the entorhinal cortex and dentate gyrus of the hippocampus was also observed and may have contributed to depressive-like behaviors. |
2023-04-03 |
2023-08-14 |
mouse |
| D V Sherbakov, A B Arefieva, P D Komleva, A E Iz'urov, N V Khotskin, D V Bazovkina, A V Kuliko. [Alterations in the Level of mRNA of TPH1, TPH2 Genes, Tryptophan Hydroxylase Activity and Serotonin Metabolism in Mouse Brain Five Days after Lipopolysaccharide Administration]. Molekuliarnaia biologiia. vol 57. issue 2. 2023-03-31. PMID:37000657. |
in the frontal cortex, hippocampus, striatum, hypothalamus, and midbrain the concentrations of 5-ht and its main metabolite, 5-hydroxyindole acetic acid (5-hiaa), and tph activity were assayed using hplc, while tph1 and tph2 mrna were quantified using quantitative real-time rt-pcr. |
2023-03-31 |
2023-08-14 |
mouse |