| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Kędziora, Serena Boccella, Ida Marabese, Jakub Mlost, Rosmara Infantino, Sabatino Maione, Katarzyna Starowic. Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB Neuropharmacology. vol 222. 2022-11-07. PMID:36341807. |
a substantial body of evidence demonstrate that hippocampal neural circuits, especially monoamine dopamine and serotonin levels, contributes to negative affect and avoidance motivation experienced during pain. |
2022-11-07 |
2023-08-14 |
rat |
| Hakimeh Saadati, Safa Ghaheri, Farshid Sadegzadeh, Nona Sakhaie, Maryam Abdollahzade. Beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal BDNF level following postnatal serotonin depletion in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-11-07. PMID:36342785. |
beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal bdnf level following postnatal serotonin depletion in male rats. |
2022-11-07 |
2023-08-14 |
rat |
| Hakimeh Saadati, Safa Ghaheri, Farshid Sadegzadeh, Nona Sakhaie, Maryam Abdollahzade. Beneficial effects of enriched environment on behavior, cognitive functions, and hippocampal BDNF level following postnatal serotonin depletion in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-11-07. PMID:36342785. |
therefore, the present study aimed to evaluate the influences of the ee housing (postnatal day: pnd21-60) following postnatal serotonin depletion (by para-chlorophenylalanine: pcpa, 100mg/kg, s.c, in pnd 10-20) on anxiety-related behaviors, cognitive functions, and brain-derived neurotrophic factor (bdnf) mrna expression in the hippocampus of male rats. |
2022-11-07 |
2023-08-14 |
rat |
| Yan Sun, Haiyan Zhu, Rongrong Cheng, Zhengquan Tang, Min Zhan. Outer membrane protein Amuc_1100 of Akkermansia muciniphila alleviates antibiotic-induced anxiety and depression-like behavior in mice. Physiology & behavior. 2022-11-06. PMID:36336146. |
in the present study, a depressed mouse model using a broad-spectrum cocktail mixture resulted in increased anxiety and depression-like behavior, decreased serum and hippocampal levels of 5-hydroxytryptamine (5-ht), and increased serum corticosterone (cort) levels. |
2022-11-06 |
2023-08-14 |
mouse |
| Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology. 2022-11-05. PMID:36334768. |
cannabidiol attenuates fear memory expression in female rats via hippocampal 5-ht growing evidence from male rodent and human studies suggests that cannabidiol (cbd) modulates the expression of aversive memories and anxiety-related responses. |
2022-11-05 |
2023-08-14 |
human |
| Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology. 2022-11-05. PMID:36334768. |
in subsequent experiments, we investigated the estrous cycle effects and the contribution of dorsal hippocampus (dh) serotonin 1a (5-ht1a) and cannabinoid types 1 (cb1) and 2 (cb2) receptors to cbd-induced effects on memory retrieval/expression. |
2022-11-05 |
2023-08-14 |
human |
| Elisabetta Gerace, Lorenzo Polenzani, Maurizio Magnani, Elisa Zianni, Gabriella Stocca, Fabrizio Gardoni, Domenico E Pellegrini-Giampietro, Renato Corradett. Antidepressant-induced increase in GluA2 expression does not translate in changes of AMPA receptor-mediated synaptic transmission at CA3/CA1 synapses in rats. Neuropharmacology. 2022-11-05. PMID:36334766. |
chronic treatment with serotonin selective reuptake inhibitors or tryciclic antidepressant drugs in rodents has been shown to increase the expression of glua1 and/or glua2 ampa receptor (ampar) subunits in several brain areas, including the hippocampus. |
2022-11-05 |
2023-08-14 |
rat |
| Irina I Belokopytova, Elena M Kondaurova, Elizabeth A Kulikova, Tatiana V Ilchibaeva, Vladimir S Naumenko, Nina K Popov. Effects of the Cc2d1a/Freud-1 Knockdown in the Hippocampus of BTBR Mice on the Autistic-Like Behavior, Expression of Serotonin 5-HT Biochemistry. Biokhimiia. vol 87. issue 10. 2022-10-23. PMID:36273889. |
effects of the cc2d1a/freud-1 knockdown in the hippocampus of btbr mice on the autistic-like behavior, expression of serotonin 5-ht the mechanisms of autism are of extreme interest due to the high prevalence of this disorder in the human population. |
2022-10-23 |
2023-08-14 |
mouse |
| Pei He, Binjun He, Shu Li, Wen Chai, Wei Rao, Yu Zhu, Wenzhi Chen, Ping Zhang, Xiong Zhang, Haili Pan, Renshi X. Distribution Features and Potential Effects of Serotonin in the Cerebrum of SOD1 G93A Transgenic Mice. eNeuro. 2022-10-20. PMID:36265904. |
both 5-ht and tryptophan hydroxylase-2 (tph2) were mainly present in the limbic systems of the cerebrum, such as the glomerular layer of the olfactory bulb, nucleus accumbens, cingulate, fimbria of the hippocampus, mediodorsal thalamic nucleus, habenular nucleus, ventromedial hypothalamus nucleus, lateral hypothalamus area, dorsal raphe nucleus and piriform cortex. |
2022-10-20 |
2023-08-14 |
mouse |
| Roberto De Gregorio, Galadu Subah, Jennifer C Chan, Luisa Speranza, Xiaolei Zhang, Aarthi Ramakrishnan, Li Shen, Ian Maze, Patric K Stanton, Ji Y Sz. Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons. Development (Cambridge, England). 2022-09-30. PMID:36178075. |
here, we identify in mice that serotonin uptake transporter (sert) in non-serotonergic neurons - hippocampal and prefrontal pyramidal neurons - confers sex-biased effects specifically during neural circuit development. |
2022-09-30 |
2023-08-14 |
mouse |
| Roberto De Gregorio, Galadu Subah, Jennifer C Chan, Luisa Speranza, Xiaolei Zhang, Aarthi Ramakrishnan, Li Shen, Ian Maze, Patric K Stanton, Ji Y Sz. Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons. Development (Cambridge, England). 2022-09-30. PMID:36178075. |
a set of gradient patterned ca3 pyramidal neurons transiently express sert to clear extracellular serotonin, coinciding with hippocampal synaptic circuit establishment. |
2022-09-30 |
2023-08-14 |
mouse |
| Ping Tian, Wei Zhang, Kai-Yan Li, Hong-Wei Li, Kai Ma, De-En Ha. [Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164876. |
western blot was used to detect the protein expressions of tryptophan hydroxylase 2(tph2), serotonin transporter(sert), and monoamine oxidase a(mao-a) in the hippocampus of rats. |
2022-09-27 |
2023-08-14 |
rat |
| Ping Tian, Wei Zhang, Kai-Yan Li, Hong-Wei Li, Kai Ma, De-En Ha. [Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164876. |
the levels of 5-ht, 5-hiaa, and 5-ht/5-hiaa in the hippocampal area were decreased(p<0.01). |
2022-09-27 |
2023-08-14 |
rat |
| Ping Tian, Wei Zhang, Kai-Yan Li, Hong-Wei Li, Kai Ma, De-En Ha. [Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164876. |
the levels of 5-ht, 5-hiaa, and 5-ht/5-hiaa in hippocampus were increased(p<0.05, p<0.01). |
2022-09-27 |
2023-08-14 |
rat |
| Ping Tian, Wei Zhang, Kai-Yan Li, Hong-Wei Li, Kai Ma, De-En Ha. [Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 17. 2022-09-27. PMID:36164876. |
the results suggested that rehmanniae radix improved depression-like behavior of cums rats, and the mechanism might be related to the regulation of synthesis, transportation, and metabolism of 5-ht neurotransmitter in the hippocampus. |
2022-09-27 |
2023-08-14 |
rat |
| Clarissa A Moura, Fernanda C Cagni, Layse Rf Costa, Pamella Rf Tiago, Mikaël Croyal, Audrey Aguesse, Luis A Reyes-Castro, Elena Zambrano, Francisco Bolaños-Jiménez, Elaine Cristina Gaviol. MATERNAL STRESS DURING PREGNANCY IN MICE INDUCES SEX-DEPENDENT BEHAVIORAL ALTERATIONS IN OFFSPRING ALONG WITH IMPAIRED SEROTONIN AND KYNURENINE PATHWAYS OF TRYPTOPHAN METABOLISM. Developmental neuroscience. 2022-09-26. PMID:36162387. |
metabolites of the kyn and 5-ht pathways were measured in the hippocampus and brainstem by ultra-performance liquid chromatography-tandem mass spectrometry. |
2022-09-26 |
2023-08-14 |
mouse |
| Clarissa A Moura, Fernanda C Cagni, Layse Rf Costa, Pamella Rf Tiago, Mikaël Croyal, Audrey Aguesse, Luis A Reyes-Castro, Elena Zambrano, Francisco Bolaños-Jiménez, Elaine Cristina Gaviol. MATERNAL STRESS DURING PREGNANCY IN MICE INDUCES SEX-DEPENDENT BEHAVIORAL ALTERATIONS IN OFFSPRING ALONG WITH IMPAIRED SEROTONIN AND KYNURENINE PATHWAYS OF TRYPTOPHAN METABOLISM. Developmental neuroscience. 2022-09-26. PMID:36162387. |
female, but not male, prenatal stressed (pns) offspring displayed a depressive-like phenotype, mainly when in proestrus/diestrus, along with reduced hippocampal 5-ht levels and high serotonin turnover rate in hippocampus and brainstem. |
2022-09-26 |
2023-08-14 |
mouse |
| Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. |
the effects of type ii pyrethroid lambda-cyhalothrin on dopamine (da) and serotonin (5-ht) synthesis in rat brain regions (striatum, hippocampus, prefrontal cortex, hypothalamus and midbrain) were studied. |
2022-09-20 |
2023-08-14 |
rat |
| Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. |
the major decreases in da and 5-ht contents were observed in hippocampus and prefrontal cortex tissues. |
2022-09-20 |
2023-08-14 |
rat |
| Bernardo Lopez-Torres, Irma Ares, Marta Martínez, Jorge-Enrique Maximiliano, María-Rosa Martínez-Larrañaga, Arturo Anadón, María-Aránzazu Martíne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-09-20. PMID:36126889. |
this research study also showed in hippocampus and prefrontal cortex, that lambda-cyhalothrin modified the mrna levels of da transporter gene (dat1 up-regulation), 5-ht transporter gene (sert down-regulation), da receptor genes (drd1and drd2 down-regulation), 5-ht receptor genes (5-ht1a and 5-ht2a down-regulation/up-regulation), da synthesis gene (th down-regulation), 5-ht synthesis gene (tph2 down-regulation), da and 5-ht degradation genes (maoa and maob up-regulation). |
2022-09-20 |
2023-08-14 |
rat |