| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander S Zubov, Irina S Ivleva, Nina S Pestereva, Tatiana V Tiutiunnik, Dmitrtii S Traktirov, Marina N Karpenk. Glibenclamide alters serotonin and dopamine levels in the rat striatum and hippocampus, reducing cognitive impairment. Psychopharmacology. 2022-05-11. PMID:35545702. |
glibenclamide alters serotonin and dopamine levels in the rat striatum and hippocampus, reducing cognitive impairment. |
2022-05-11 |
2023-08-13 |
rat |
| Huawei Li, Peng Wang, Yunping Zhou, Fei Zhao, Xue Gao, Chunfeng Wu, Tianxia Wu, Liping Jiang, Dianliang Zhan. Correlation between intestinal microbiotal imbalance and 5-HT metabolism, immune inflammation in chronic unpredictable mild stress male rats. Genes, brain, and behavior. 2022-05-10. PMID:35535862. |
the concentrations of 5-ht and tph2 in the prefrontal and hippocampal tissues were lower, while ido1 was higher. |
2022-05-10 |
2023-08-13 |
rat |
| Lin-Ru Zhao, Pan He, Jie Li, Ya-Jun Zhang, Jing-Xing Jiang, Ying-Ru Wu, Yue Zhang, Jia Li, Cong Liu, Xu-Liang Ha. [Sleep-improving mechanism of Chaiqin Ningshen Granules in insomnia rats: based on hippocampal metabonomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 7. 2022-05-09. PMID:35534263. |
the results show that the drugs can significantly improve the mental state, liver depression, and blood stasis of rats, significantly increase the content of 5-hydroxytryptamine(5-ht) and gamma aminobutyric acid(gaba) in hippocampus(except low-dose cng), and significantly reduce the content of glucose(glu)(except low-dose cng). |
2022-05-09 |
2023-08-13 |
rat |
| Hongmei Wu, Gang Zhao, Sijin Liu, Quanzhi Zhang, Peng Wang, Yonggang Cao, Lijie W. Supplementation with Selenium Attenuates Autism-Like Behaviors and Improves Oxidative Stress, Inflammation and Related Gene Expression in an Autism Disease Model. The Journal of nutritional biochemistry. 2022-05-02. PMID:35500829. |
the administration of sodium selenite in btbr mice: (1) increased the expression of selp; (2) attenuated spatial learning, memory impairment and improved social behaviors; (3) changed the serum levels of 5-ht, da and glu; (4) decreased the levels of inflammatory cytokines il-6, il-1β, and tnf-α in serum and hippocampal tissue; (5) reduced the ros and mda contents and significantly increased sod activity, cat activity, gsh-px activity, and antioxidant gsh levels; and (6) protected against neuronal loss in the hippocampus. |
2022-05-02 |
2023-08-13 |
mouse |
| Smriti Patodia, Alyma Somani, Joan Liu, Alice Cattaneo, Beatrice Paradiso, Maria Garcia, Muhammad Othman, Beate Diehl, Orrin Devinsky, James D Mills, Jackie Foong, Maria Tho. Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP. Brain pathology (Zurich, Switzerland). 2022-04-28. PMID:35478467. |
serotonin transporter in the temporal lobe, hippocampus and amygdala in sudep. |
2022-04-28 |
2023-08-13 |
Not clear |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
the ability of cholecalciferol to elicit an antidepressant-like effect and to modulate serotonin levels in the hippocampus and prefrontal cortex of mice subjected to chronic unpredictable stress (cus) was also investigated. |
2022-04-18 |
2023-08-13 |
mouse |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
additionally, cus protocol (21 days) induced depressive-like behavior in the tail suspension test and decreased serotonin levels in the prefrontal cortex and hippocampus of mice. |
2022-04-18 |
2023-08-13 |
mouse |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
cholecalciferol was also effective to abrogate cus-induced reduction on serotonin levels in the prefrontal cortex, but not in the hippocampus. |
2022-04-18 |
2023-08-13 |
mouse |
| Rebeca Vindas-Smith, Dayana Quesada, Mónica I Hernández-Solano, Maripaz Castro, Andrey Sequeira-Cordero, Jaime Fornaguera, Georgina Gómez, Juan C Brene. Fat intake and obesity-related parameters predict striatal BDNF gene expression and dopamine metabolite levels in cafeteria diet-fed rats. Neuroscience. 2022-04-10. PMID:35398176. |
the cafeteria diet increased bdnf expression in the dorsal striatum (ds), and norepinephrine, 5-ht, trkb, creb, and dnmt3a levels in the hippocampus. |
2022-04-10 |
2023-08-13 |
rat |
| Jia-Xing Liu, Jia-Han Li, Chen-Hui DU, Yan Ya. [Metabonomic study of biochemical changes in serum of PCPA-induced insomnia rats after treatment with Suanzaoren Decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 6. 2022-03-29. PMID:35347962. |
then pathological changes of the liver and brain were observed and biochemical indexes such as 5-hydroxytryptamine(5-ht), dopamine(da), glutamate(glu), γ-aminobutyric acid(gaba), and norepinephrine(ne) in the hippocampus and prostaglandin d2(pgd2), tumor necrosis factor-α(tnf-α), interleukin-1β(il-1β), and il-6 in the serum of rats were detected. |
2022-03-29 |
2023-08-13 |
rat |
| Jia-Xing Liu, Jia-Han Li, Chen-Hui DU, Yan Ya. [Metabonomic study of biochemical changes in serum of PCPA-induced insomnia rats after treatment with Suanzaoren Decoction]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 6. 2022-03-29. PMID:35347962. |
the results showed that szrd could improve the pathological changes of brain and liver tissues, increase the levels of neurotransmitters 5-ht, da, and gaba in hippocampus and the level of pgd2 in hypothalamic-pituitary-adrenal axis(hpa axis), and reduce the levels of il-1β and tnf-α in serum of insomnia rats. |
2022-03-29 |
2023-08-13 |
rat |
| Yun Wang, Mixia Wang, Yuchuan Dai, Yilin Song, Yiding Wang, Botao Lu, Yinghui Li, Xinxia Ca. PtNPs/Short MWCNT-PEDOT: PSS-Modified Microelectrode Array to Detect Neuronal Firing Patterns in the Dorsal Raphe Nucleus and Hippocampus of Insomnia Rats. Micromachines. vol 13. issue 3. 2022-03-26. PMID:35334780. |
in order to explore the effect of 5-ht deficiency-induced insomnia on brain regions related to memory in rats, we designed and fabricated a microelectrode array that simultaneously detects the electrical activity of the dorsal raphe nucleus (drn) and hippocampus in normal, insomnia and recovery rats in vivo. |
2022-03-26 |
2023-08-13 |
rat |
| Yun Wang, Mixia Wang, Yuchuan Dai, Yilin Song, Yiding Wang, Botao Lu, Yinghui Li, Xinxia Ca. PtNPs/Short MWCNT-PEDOT: PSS-Modified Microelectrode Array to Detect Neuronal Firing Patterns in the Dorsal Raphe Nucleus and Hippocampus of Insomnia Rats. Micromachines. vol 13. issue 3. 2022-03-26. PMID:35334780. |
our findings suggest that 5-ht deficiency causes the hyperactivity of neurons in the hippocampus and drn; the drn's firing rate and the hippocampal neuronal amplitude reflect insomnia in rats more effectively. |
2022-03-26 |
2023-08-13 |
rat |
| Runlong Zhao, Yalin Zhou, Hanxu Shi, Wanyun Ye, Ying Lyu, Zhang Wen, Rui Li, Yajun X. Effect of Gestational Diabetes on Postpartum Depression-like Behavior in Rats and Its Mechanism. Nutrients. vol 14. issue 6. 2022-03-26. PMID:35334886. |
the hpa axis hormone did not show the typical stress state of depression, but the level of 5-ht decreased significantly in serum, prefrontal cortex and hippocampus, and the kyn/trp ratio increased significantly in serum and prefrontal cortex, implying the switch of the tryptophan (trp) metabolism from the 5-ht pathway to the kynurenine (kyn) pathway. |
2022-03-26 |
2023-08-13 |
rat |
| Britt T J van Hagen, Nick P van Goethem, Ellis Nelissen, Dean Paes, Karin Koymans, Scott van Hoof, Rudy Schreiber, Mark Varney, Adrian Newman-Tancredi, Jos Prickaert. Biased 5-HT Molecular and cellular neurosciences. 2022-03-14. PMID:35283305. |
biased 5-ht pattern separation is a hippocampal process in which highly similar stimuli are recognized as separate representations, and deficits could lead to memory impairments in neuropsychiatric disorders such as schizophrenia. |
2022-03-14 |
2023-08-13 |
Not clear |
| Princewill Ikechukwu Ugwu, Benneth Ben-Azu, Sandra Ugonne Ugwu, Christian I Uruaka, Chinecherem Choice Nworgu, Pamela Onyinye Okorie, Kizito Oluchukwu Okafor, Kenneth Kelechi Anachuna, Melford Uche Elendu, Amogechukwu Onyinye Ugwu, Ugochukwu Bond Anyaehie, Azubuike A Nwankwo, Eme Effiom Osi. Putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin. Brain research bulletin. 2022-03-12. PMID:35278662. |
the decreased serotonin in the prefrontal-cortex and dopamine in the striatum, elevated levels of noradrenaline and acetylcholinesterase in the prefrontal-cortex and hippocampus with corresponding decrease in bdnf were reversed by quercetin. |
2022-03-12 |
2023-08-13 |
mouse |
| Kateryna Murlanova, Netanela Cohen, Anna Pinkus, Liudmila Vinnikova, Mikhail Pletnikov, Michael Kirby, Jonathan Gorelick, Elyashiv Drori, Albert Pinhaso. Antidepressant-like effects of a chlorogenic acid- and cynarine-enriched fraction from Dittrichia viscosa root extract. Scientific reports. vol 12. issue 1. 2022-03-08. PMID:35256610. |
neurochemical profiling for 5-hydroxytryptamine (5-ht) and its primary metabolite, 5-hydroxyindoleacetic acid (5-hiaa), in prefrontal cortex and hippocampus of "k"-treated mice showed reduction in 5-hiaa, indicative of either serotonin uptake transporter or monoamine oxidase-a inhibition, as well as slight increases in 5-ht content. |
2022-03-08 |
2023-08-13 |
mouse |
| Hongxuan Kuang, Wenji Zhou, Yingwei Zeng, Da Xu, Wanqi Zhu, Shengjie Lin, Ruifang Fa. Dose makes poison: Insights into the neurotoxicity of perinatal and juvenile exposure to environmental doses of 16 priority-controlled PAHs. Chemosphere. 2022-03-08. PMID:35257710. |
except for serotonin, no significant difference in hippocampal and cortical neurotransmitter concentrations was observed between the control and pahs-exposed groups. |
2022-03-08 |
2023-08-13 |
mouse |
| Aanchal Aggarwal, Aarti Yadav, Neetu Saini, Rajat Sandhi. S-nitrosoglutathione alleviates hyperglycemia-induced neurobehavioral deficits involving nitro-oxidative stress and aberrant monaminergic system. Nitric oxide : biology and chemistry. 2022-03-08. PMID:35257853. |
these neurobehavioral deficits observed in diabetic mice could be attributed to decrease in norepinephrine (ne), dopamine (da), serotonin (5-ht) and increased monoamine oxidase (mao) activity in cortex and hippocampus. |
2022-03-08 |
2023-08-13 |
mouse |
| Sreyashi Samaddar, Sudarshana Purkayastha, Souleymane Diallo, Subramanyam J Tantry, Ryan Schroder, Pranavan Chanthrakumar, Michael J Flory, Probal Banerje. The G Protein-Coupled Serotonin 1A Receptor Augments Protein Kinase Cε-Mediated Neurogenesis in Neonatal Mouse Hippocampus-PKCε-Mediated Signaling in the Early Hippocampus. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216076. |
the g protein-coupled serotonin 1a receptor augments protein kinase cε-mediated neurogenesis in neonatal mouse hippocampus-pkcε-mediated signaling in the early hippocampus. |
2022-02-26 |
2023-08-13 |
mouse |