| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuke Han, Huangan Wu, Ping Yin, Zeqin Chen, Xiaohua Cao, Yanhong Duan, Jian Xu, Lixing Lao, Shifen X. Electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-HT receptors in a rat model of depression. Brain research bulletin. vol 139. 2019-03-12. PMID:29524471. |
electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-ht receptors in a rat model of depression. |
2019-03-12 |
2023-08-13 |
rat |
| Yuanyuan Liu, Mengying Wei, Kexin Yue, Mingxin Hu, Shizhe Li, Lihui Men, Zifeng Pi, Zhiqiang Liu, Zhongying Li. Study on Urine Metabolic Profile of Aβ25-35-Induced Alzheimer's Disease Using UHPLC-Q-TOF-MS. Neuroscience. vol 394. 2019-03-01. PMID:30316910. |
in addition, the levels of γ-aminobutyric acid, acetylcholine, glycine, norepinephrine, serotonin, taurine and dopamine decreased and glutamate and aspartic acid increased in hippocampal tissue of ad rats. |
2019-03-01 |
2023-08-13 |
rat |
| Xuan Liu, Ge Jin, Bilian Fan, Yang Xing, Lei Wang, Min Wang, Yueming Yuan, Qiwen Zh. The impact of ALDH2 activation by Alda-1 on the expression of VEGF in the hippocampus of a rat model of post-MI depression. Neuroscience letters. vol 674. 2019-02-25. PMID:29574217. |
these behaviors were associated with an increase 5-ht and da neurotransmitter content, as well as an increase of vegf levels in the hippocampus of the post-mi depression rats. |
2019-02-25 |
2023-08-13 |
rat |
| Silvia Vincentiis, Juliana Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Sebastiao E Melo-Souza, Francisco Arruda, Paulo Ragazzo, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 83. 2019-02-25. PMID:29709878. |
genetic polymorphisms of the 5ht receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. |
2019-02-25 |
2023-08-13 |
Not clear |
| Huali Wu, Wenting Lv, Qi Pan, Praveen Kumar Kalavagunta, Qiongzhen Liu, Guohong Qin, Minxuan Cai, Liangliang Zhou, Tao Wang, Zhenjiang Xia, Jing Shan. Simvastatin therapy in adolescent mice attenuates HFD-induced depression-like behavior by reducing hippocampal neuroinflammation. Journal of affective disorders. vol 243. 2019-02-25. PMID:30236762. |
however, the studies on the hfd exposure in adolescent animals, which investigate the neuroprotective effects of smv on the hippocampal morphology, serotonin (5-ht) system and inflammation, are limited. |
2019-02-25 |
2023-08-13 |
mouse |
| Katrine Skovgård, Claus Agerskov, Kristi A Kohlmeier, Kjartan F Herri. The 5-HT Neuropharmacology. vol 143. 2019-02-25. PMID:30243914. |
the 5-ht cognitive impairments in alzheimer's disease (ad) have been associated with alterations in neuronal oscillatory activity, of which hippocampal theta and gamma oscillations are essential for the coordination of neuronal networks during cognitive functions. |
2019-02-25 |
2023-08-13 |
Not clear |
| Eric Brown, Conor J Mc Veigh, Leilani Santos, Martina Gogarty, Heidi Kaastrup Müller, Betina Elfving, David J Brayden, Jana Haas. TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology. vol 137. 2019-02-20. PMID:29723540. |
tnfα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. |
2019-02-20 |
2023-08-13 |
mouse |
| J E Beilharz, N O Kaakoush, J Maniam, M J Morri. Cafeteria diet and probiotic therapy: cross talk among memory, neuroplasticity, serotonin receptors and gut microbiota in the rat. Molecular psychiatry. vol 23. issue 2. 2019-02-15. PMID:28289278. |
in the hippocampus, the caf diet increased the expression of many genes related to neuroplasticity and serotonin receptor (5ht) 1a, which was normalised in caf-high rats. |
2019-02-15 |
2023-08-13 |
human |
| Janaína da Silva Rocha-Lopes, Ricardo Borges Machado, Deborah Sucheck. Chronic REM Sleep Restriction in Juvenile Male Rats Induces Anxiety-Like Behavior and Alters Monoamine Systems in the Amygdala and Hippocampus. Molecular neurobiology. vol 55. issue 4. 2019-02-11. PMID:28455701. |
these animals also exhibited higher noradrenaline levels in the amygdala and ventral hippocampus, without any change in the expression of β1-adrenergic receptors, as well as higher serotonin and reduced turnover in the dorsal hippocampus, with diminished expression of 5-ht1 |
2019-02-11 |
2023-08-13 |
rat |
| Ana Agusti, A Moya-Pérez, I Campillo, S Montserrat-de la Paz, V Cerrudo, A Perez-Villalba, Yolanda San. Bifidobacterium pseudocatenulatum CECT 7765 Ameliorates Neuroendocrine Alterations Associated with an Exaggerated Stress Response and Anhedonia in Obese Mice. Molecular neurobiology. vol 55. issue 6. 2019-02-04. PMID:28921462. |
furthermore, the bifidobacterial strain reduced the obesity-induced upregulation of tlr2 protein or gene expression in the intestine (p < 0.010) and the hippocampus (p < 0.050) and restored the alterations of 5-ht levels in the hippocampus (p < 0.050), which could contribute to attenuating the obesity-associated depressive-like behavior (p < 0.050). |
2019-02-04 |
2023-08-13 |
mouse |
| Julien Volle, Tatiana Bregman, Brian Scott, Mustansir Diwan, Roger Raymond, Paul J Fletcher, José N Nobrega, Clement Haman. Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system. Neuropharmacology. vol 135. 2019-02-04. PMID:29505786. |
samples to measure serotonin levels were collected from the hippocampus using microdialysis. |
2019-02-04 |
2023-08-13 |
rat |
| Zhi-Kun Qiu, De-Sheng Zhong, Jia-Li He, Xu Liu, Ji-Sheng Chen, Hong Ni. The anxiolytic-like effects of puerarin are associated with the changes of monoaminergic neurotransmitters and biosynthesis of allopregnanolone in the brain. Metabolic brain disease. vol 33. issue 1. 2019-01-31. PMID:29101599. |
moreover, the present study also found that consistent with ser, the levels of allopregnanolone and serotonin (5-ht) in the prefrontal cortex and hippocampus were increased by puerarin (60 and 120 mg/kg, i.g. |
2019-01-31 |
2023-08-13 |
Not clear |
| Huali Wu, Qiongzhen Liu, Praveen Kumar Kalavagunta, Qiaoling Huang, Wenting Lv, Xiaohong An, Haijuan Chen, Tao Wang, Rakotomalala Manda Heriniaina, Tong Qiao, Jing Shan. Normal diet Vs High fat diet - A comparative study: Behavioral and neuroimmunological changes in adolescent male mice. Metabolic brain disease. vol 33. issue 1. 2019-01-31. PMID:29101600. |
at the end of 6th week hippocampal analysis revealed the differences in morphology (reduced nissl positive neurons and decreased the 5-ht |
2019-01-31 |
2023-08-13 |
mouse |
| F Sh Shagiakhmetov, P K Anokhin, A O Popova, I Yu Shamakin. [A profile of antidepressive effects of agomelatine and a current view on the mechanism of its action]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 117. issue 12. 2019-01-29. PMID:29376995. |
besides the effect on suprachiasmatic nucleus, a relevant role in the mechanism of action of agomelatine plays its special functionally selective (with regard to intracellular signaling pathways) interaction with heteromeric complexes of serotonin 5-НТ2С and melatonin mt2 receptors in the hippocampus and cerebral cortex. |
2019-01-29 |
2023-08-13 |
Not clear |
| Shengbing Liu, Shuiling Xu, Zhijian Wang, Yanjun Guo, Weiwei Pan, Zhongfei She. Anti-Depressant-Like Effect of Sinomenine on Chronic Unpredictable Mild Stress-Induced Depression in a Mouse Model. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-01-07. PMID:30362468. |
the levels of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and proinflammatory cytokines (interleukin-1β [il-1β] interleukin-6 [il-6], and tumor necrosis factor-α [tnf-α]) in the hippocampus of mice were detected by elisa assay. |
2019-01-07 |
2023-08-13 |
mouse |
| Shengbing Liu, Shuiling Xu, Zhijian Wang, Yanjun Guo, Weiwei Pan, Zhongfei She. Anti-Depressant-Like Effect of Sinomenine on Chronic Unpredictable Mild Stress-Induced Depression in a Mouse Model. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-01-07. PMID:30362468. |
in addition, sin decreased cums-induced reduction in the concentrations of ne and 5-ht in the hippocampus of mice. |
2019-01-07 |
2023-08-13 |
mouse |
| Nayara Pestana-Oliveira, Bruna Kalil, Cristiane Mota Leite, Ruither Oliveira Gomes Carolino, Lucas Kniess Debarba, Lucila Leico Kagohara Elias, José Antunes-Rodrigues, Janete A Anselmo-Franc. Effects of Estrogen Therapy on the Serotonergic System in an Animal Model of Perimenopause Induced by 4-Vinylcyclohexen Diepoxide (VCD). eNeuro. vol 5. issue 1. 2019-01-02. PMID:29362726. |
blood was collected for hormone measurement, the brains were removed and dorsal raphe nucleus (drn), hippocampus (hpc), and amygdala (amy) punched out for serotonin (5-ht), estrogen receptor β (erβ), and progesterone receptor (pr) mrna level measurements. |
2019-01-02 |
2023-08-13 |
rat |
| Mei Huang, Sunoh Kwon, Lakshmi Rajagopal, Wenqi He, Herbert Y Meltze. 5-HT Psychopharmacology. vol 235. issue 10. 2018-12-31. PMID:30066135. |
5-ht the effect of atypical antipsychotic drugs (aapds), e.g., lurasidone, to improve cognitive impairment associated with schizophrenia (cias), has been suggested to be due, in part, to enhancing release of dopamine (da), acetylcholine (ach), and glutamate (glu) in cortex and hippocampus. |
2018-12-31 |
2023-08-13 |
Not clear |
| M G Gottschalk, P Mortas, M Haman, S Ozcan, B Biemans, S Bah. Fluoxetine, not donepezil, reverses anhedonia, cognitive dysfunctions and hippocampal proteome changes during repeated social defeat exposure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 1. 2018-12-11. PMID:29174946. |
we evaluated the behavioural and molecular effects of a selective serotonin re-uptake inhibitor (ssri, fluoxetine) and an acetylcholinesterase inhibitor (achei, donepezil) on emotional-cognitive endophenotypes of depression and the hippocampal proteome. |
2018-12-11 |
2023-08-13 |
Not clear |
| Arnold Gutierrez, Michael T Williams, Charles V Vorhee. A Single High Dose of Methamphetamine Reduces Monoamines and Impairs Egocentric and Allocentric Learning and Memory in Adult Male Rats. Neurotoxicity research. vol 33. issue 3. 2018-12-11. PMID:29427284. |
ma-treated rats had persistent dopamine and serotonin reductions in the neostriatum and nucleus accumbens, and serotonin reductions in the hippocampus of the same magnitude as in repetitive treatment models. |
2018-12-11 |
2023-08-13 |
rat |