| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
taken together, our data suggest that sak3 promotes monoamine da and 5-ht releases by enhancing the t-type calcium channel and nachr in the mouse hippocampus. |
2019-04-29 |
2023-08-13 |
mouse |
| Frances Xin, Erin Fischer, Christopher Krapp, Elizabeth N Krizman, Yemin Lan, Clementina Mesaros, Nathaniel W Snyder, Amita Bansal, Michael B Robinson, Rebecca A Simmons, Marisa S Bartolome. Mice exposed to bisphenol A exhibit depressive-like behavior with neurotransmitter and neuroactive steroid dysfunction. Hormones and behavior. vol 102. 2019-04-25. PMID:29763587. |
high performance liquid chromatography demonstrated a male-specific reduction in hippocampal serotonin. |
2019-04-25 |
2023-08-13 |
mouse |
| Karen K Y Lee, Chloe N Soutar, Hans C Dringenber. Gating of long-term potentiation (LTP) in the thalamocortical auditory system of rats by serotonergic (5-HT) receptors. Brain research. vol 1683. 2019-04-19. PMID:29325855. |
the neuromodulator serotonin (5-hydroxytryptamine, 5-ht) plays an important role in controlling the induction threshold and maintenance of long-term potentiation (ltp) in the visual cortex and hippocampus of rodents. |
2019-04-19 |
2023-08-13 |
rat |
| Haitham S Mohammed, Yasser A Khadrawy, Tharwat M El-Sherbini, Hanaa M Ame. Electrocortical and Biochemical Evaluation of Antidepressant Efficacy of Formulated Nanocurcumin. Applied biochemistry and biotechnology. vol 187. issue 3. 2019-04-17. PMID:30167967. |
the chronic administration of reserpine resulted in a significant decrease in the duration of the active phase in the fst; a significant decrease in the cortical and hippocampal levels of serotonin, norepinephrine, and dopamine; a significant increase in spectral power of alpha and delta waves; and a significant decrease in spectral power of theta, beta-1, and beta-2 waves with respect to control values. |
2019-04-17 |
2023-08-13 |
rat |
| Haitham S Mohammed, Yasser A Khadrawy, Tharwat M El-Sherbini, Hanaa M Ame. Electrocortical and Biochemical Evaluation of Antidepressant Efficacy of Formulated Nanocurcumin. Applied biochemistry and biotechnology. vol 187. issue 3. 2019-04-17. PMID:30167967. |
additionally, the levels of serotonin and dopamine have been restored; however, the level of norepinephrine has been not completely recovered in both cortex and hippocampus. |
2019-04-17 |
2023-08-13 |
rat |
| Yong-Ku Kim, Meysam Amidfar, Eunsoo Wo. A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in post-traumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 91. 2019-04-15. PMID:29932946. |
such heightened activity of the immune system may cause alterations in the structure and function of brain regions-for example, the amygdala, hippocampus, medial prefrontal cortex, anterior cingulate cortex, and insula-through changes in levels of serotonin and kynurenine pathway metabolites, and direct neurotoxic effects of cytokines. |
2019-04-15 |
2023-08-13 |
Not clear |
| Hanjie Yu, Dan Lv, Mengxin Shen, Yanhua Zhang, Dongsheng Zhou, Zhongming Chen, Chuang Wan. BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1. Psychiatry research. vol 271. 2019-04-15. PMID:30529315. |
in addition, the reserpine-induced decreases in serotonin transporter (5-htt), brain-derived neurotrophic factor (bdnf) and tryptophan hydroxylase 1 (tph1) in mouse hippocampus and prefrontal cortex (pfc) were significantly reversed by scopolamine. |
2019-04-15 |
2023-08-13 |
mouse |
| Zhi-Kun Qiu, Guan-Hua Zhang, De-Sheng Zhong, Jia-Li He, Xu Liu, Ji-Sheng Chen, Da-Nian We. Puerarin ameliorated the behavioral deficits induced by chronic stress in rats. Scientific reports. vol 7. issue 1. 2019-04-10. PMID:28740098. |
in addition, enzyme linked immunosorbent assay (elisa) and high performance liquid chromatography-electrochemical detection (hplc-ecd) showed that chronic treatment of puerarin (60 and 120 mg/kg, i.g) reversed the decreased levels of progesterone, allopregnanolone, serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in prefrontal cortex and hippocampus of post-cus rats. |
2019-04-10 |
2023-08-13 |
rat |
| Yuanyuan Liu, Zhongying Liu, Mengying Wei, Mingxin Hu, Kexin Yue, Rongbing Bi, Shan Zhai, Zifeng Pi, Fengrui Song, Zhiqiang Li. Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's disease. Food & function. vol 10. issue 1. 2019-04-09. PMID:30623955. |
in the hippocampus of the model rats, the contents of γ-aminobutyric acid, acetylcholine, glycine, norepinephrine, taurine, serotonin and dopamine were significantly decreased and the contents of glutamate and aspartic acid were increased significantly. |
2019-04-09 |
2023-08-13 |
rat |
| M Kondo, Y Koyama, Y Nakamura, S Shimad. A novel 5HT3 receptor-IGF1 mechanism distinct from SSRI-induced antidepressant effects. Molecular psychiatry. vol 23. issue 4. 2019-04-04. PMID:28439104. |
in this study, we show that a serotonin type 3 receptor (5ht3r) agonist induces antidepressant effects as well as hippocampal neurogenesis independent of fluoxetine (a commonly used ssri). |
2019-04-04 |
2023-08-13 |
Not clear |
| Aya Abdalla, Christopher W Atcherley, Pavithra Pathirathna, Srimal Samaranayake, Beidi Qiang, Edsel Peña, Stephen L Morgan, Michael L Heien, Parastoo Hashem. In Vivo Ambient Serotonin Measurements at Carbon-Fiber Microelectrodes. Analytical chemistry. vol 89. issue 18. 2019-04-01. PMID:28795565. |
in vivo, we report basal serotonin levels in the ca2 region of the hippocampus as 64.9 ± 2.3 nm (n = 15 mice, weighted average ± standard error). |
2019-04-01 |
2023-08-13 |
mouse |
| Zhi-Kun Qiu, Jia-Li He, Xu Liu, Jia Zeng, Wei Xiao, Qing-Hong Fan, Xiao-Meng Chai, Wei-Hai Ye, Ji-Sheng Che. Anxiolytic-like effects of paeoniflorin in an animal model of post traumatic stress disorder. Metabolic brain disease. vol 33. issue 4. 2019-04-01. PMID:29633071. |
moreover, the decreased levels of serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in prefrontal cortex and hippocampus were reversed by pf (10 and 20 mg/kg, i.p. |
2019-04-01 |
2023-08-13 |
rat |
| Girdhari Lal Gupta, Joneth Fernande. Protective effect of Convolvulus pluricaulis against neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-04-01. PMID:30551424. |
furthermore, a one-week treatment of cpe (50 and 100 mg/kg) or fluoxetine also remarkably restored the serotonin and noradrenaline levels in the hippocampus as well as in the prefrontal cortex of the cums-exposed rats. |
2019-04-01 |
2023-08-13 |
rat |
| A C Pereira, M C Carvalho, C M Padova. Both serotonergic and noradrenergic systems modulate the development of tolerance to chronic stress in rats with lesions of the serotonergic neurons of the median raphe nucleus. Behavioural brain research. vol 357-358. 2019-03-29. PMID:28662893. |
fluoxetine attenuated the anxiogenic-induced effect of lesion in chronically restrained rats, without changing serotonin and noradrenaline levels in the hippocampus of lesioned rats. |
2019-03-29 |
2023-08-13 |
rat |
| Cheng-Yun Cai, Hai-Yin Wu, Chun-Xia Luo, Dong-Ya Zhu, Yu Zhang, Qi-Gang Zhou, Jing Zhan. Extracellular regulated protein kinaseis critical for the role of 5-HT1a receptor in modulating nNOS expression and anxiety-related behaviors. Behavioural brain research. vol 357-358. 2019-03-29. PMID:29246772. |
our previous study found that serotonin 1a receptor (5-ht1ar) is an endogenous suppressor of nnos expression in the hippocampus, which accounts for anxiolytic effect of fluoxetine. |
2019-03-29 |
2023-08-13 |
Not clear |
| Boris Mlinar, Renato Corradett. Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis. Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29266595. |
differential modulation of ca1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis. |
2019-03-26 |
2023-08-13 |
rat |
| Boris Mlinar, Renato Corradett. Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis. Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29266595. |
to examine the modulation of hippocampal output along the dorsoventral axis by endogenous serotonin (5-ht) we compared the effect of the 5-ht/noradrenaline (na)-releaser, 3,4-methylenedioxymethamphetamine (mdma), in transversal slices encompassing the entire rat hippocampus. |
2019-03-26 |
2023-08-13 |
rat |
| Boris Mlinar, Renato Corradett. Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis. Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29266595. |
co-release of 5-ht and na by mdma resulted in a gradient of effects on evoked population spikes in the ca1 area along the dorsoventral axis of the hippocampus. |
2019-03-26 |
2023-08-13 |
rat |
| Boris Mlinar, Renato Corradett. Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis. Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29266595. |
selective 5-ht release decreased population spike amplitude in slices from dorsal hippocampus, whereas an increase was produced in the ventral hippocampus, indicating differential modulation of ca1 impulse flow along the dorsoventral axis by endogenous 5-ht. |
2019-03-26 |
2023-08-13 |
rat |
| Yashika Bansal, Raghunath Singh, Priyanka Saroj, Rupinder Kaur Sodhi, Anurag Kuha. Naringenin protects against oxido-inflammatory aberrations and altered tryptophan metabolism in olfactory bulbectomized-mice model of depression. Toxicology and applied pharmacology. vol 355. 2019-03-14. PMID:30017640. |
naringenin reversed altered levels of tryptophan, serotonin, 5-hydroxyindole acetic acid and kynurenine in hippocampus and cortex. |
2019-03-14 |
2023-08-13 |
mouse |