| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
moreover, we also found that cort levels in serum were significantly increased, along with the decrease of brain-derived neurotrophic factor (bdnf) mrna, bdnf protein, 5-hydroxytryptamine (5-ht) and norepinephrine (ne) levels in the hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
the data collected here confirms that re-exposure to the context of morphine administration after the withdrawal period increases the level of 50-khz usvs and this contextual response is associated with elevated serotonin concentrations in amygdala, hippocampus and mpfc and with increased glu/gln ratio in nucleus accumbens. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
the concentration of serotonin increases simultaneously in amygdala, nucleus accumbens and hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
moreover, 5-ht concentration in amygdala is bound up with glutamate level in this structure as well as in hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Matthew J Robson, Meagan A Quinlan, Kara Gross Margolis, Paula A Gajewski-Kurdziel, Jeremy Veenstra-VanderWeele, Michael D Gershon, D Martin Watterson, Randy D Blakel. p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 43. 2018-12-11. PMID:30297392. |
mice expressing the most common of these variants (sert ala56) exhibit hyperserotonemia, a biomarker observed in asd subjects, as well as p38 mapk-dependent sert hyperphosphorylation, elevated hippocampal 5-ht clearance, hypersensitivity of cns 5-ht |
2018-12-11 |
2023-08-13 |
mouse |
| Benneth Ben-Azu, Adegbuyi Oladele Aderibigbe, Aya-Ebi Okubo Eneni, Abayomi Mayowa Ajayi, Solomon Umukoro, Ezekiel O Iwalew. Morin Attenuates Neurochemical Changes and Increased Oxidative/Nitrergic Stress in Brains of Mice Exposed to Ketamine: Prevention and Reversal of Schizophrenia-Like Symptoms. Neurochemical research. vol 43. issue 9. 2018-11-21. PMID:29956036. |
thereafter, the brain levels of dopamine, glutamate, 5-hydroxytryptamine and acetyl-cholinesterase, as well as biomarkers of oxidative/nitrergic stress were measured in the striatum, prefrontal-cortex (pfc) and hippocampus (hc). |
2018-11-21 |
2023-08-13 |
mouse |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in wistar rats. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
however, little is known about the effect of sequential exposure to ethanol and meth on glutamate, dopamine and serotonin tissue content in striatum and hippocampus. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
in the hippocampus, sequential exposure to ethanol and meth decreased serotonin tissue content as compared to the group that was exposed to ethanol alone. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
however, this study showed that ethanol has no additive effect to meth on tissue content of dopamine and serotonin as compared to meth in the striatum and hippocampus. |
2018-11-13 |
2023-08-13 |
rat |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
in addition, in the hippocampus and cortex, the levels of 5-ht and da were significantly decreased in the cums group compared with the control group (p < 0.05). |
2018-10-30 |
2023-08-13 |
mouse |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
in comparison with the cums group, paroxetine obviously increased the da levels in the hippocampus and the cortex and the 5-ht level in the hippocampus (p < 0.05). |
2018-10-30 |
2023-08-13 |
mouse |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
the 5-ht level in the 200 mg/kg dnl group was notably increased in both two brain regions (p < 0.05), but the 5-ht level in the 100 mg/kg dnl group was significantly increased only in the hippocampus (p < 0.01). |
2018-10-30 |
2023-08-13 |
mouse |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
these findings indicate that the extract of dnl has an antidepressant-like effect on cums-induced depressive mice and its mechanism may be related to the changes in da and 5-ht in the hippocampus and cortex. |
2018-10-30 |
2023-08-13 |
mouse |
| Dasiel O Borroto-Escuela, Manuel Narváez, Patrizia Ambrogini, Luca Ferraro, Ismel Brito, Wilber Romero-Fernandez, Yuniesky Andrade-Talavera, Antonio Flores-Burgess, Carmelo Millon, Belen Gago, Jose Angel Narvaez, Yuji Odagaki, Miklos Palkovits, Zaida Diaz-Cabiale, Kjell Fux. Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. Molecules (Basel, Switzerland). vol 23. issue 6. 2018-10-22. PMID:29865267. |
the 5-ht1a⁻fgfr1 heteroreceptor complexes were involved in synergistically enhancing neuroplasticity in the hippocampus and in the dorsal raphe 5-ht nerve cells. |
2018-10-22 |
2023-08-13 |
rat |
| I V Karpova, V V Mikheev, V V Marysheva, N A Kuritcyna, N A Popkovskii, E R Bychkov, P D Shabano. [The effect of acute hypoxia with hypercapnia on the content of monoamines in symmetrical areas of the brain in albino mice]. Biomeditsinskaia khimiia. vol 64. issue 3. 2018-10-16. PMID:29964262. |
the concentrations of dopamine (da), serotonin (5-ht) and their metabolites dihydroxyphenylacetic (dopac), homovanilic (hva) and 5-hydroxyindolacetic (5-hiaa) acids were measured by hplc in the brain cortex, hippocampus and striatum of the right and the left hemispheres. |
2018-10-16 |
2023-08-13 |
mouse |
| Rui Yang, Wei Chen, Ye Lu, Yingke Li, Hongli Du, Songyan Gao, Xin Dong, Hongbin Yua. Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism. Scientific reports. vol 7. 2018-10-15. PMID:28059131. |
in addition, dioscin a natural steroidal saponin isolated from chinese medicinal herbs, enhanced the serotonergic system and produced anti-depressant effect by enhancing 5-ht levels in hippocampus. |
2018-10-15 |
2023-08-13 |
Not clear |
| Rui Yang, Wei Chen, Ye Lu, Yingke Li, Hongli Du, Songyan Gao, Xin Dong, Hongbin Yua. Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism. Scientific reports. vol 7. 2018-10-15. PMID:28059131. |
what is more, this finding was verified by metabolic analyses of hippocampus, indicating 5-ht related metabolic pathway was involved in the pathogenesis of endotoxemia induced acute neuro-inflammation. |
2018-10-15 |
2023-08-13 |
Not clear |
| Rui Yang, Wei Chen, Ye Lu, Yingke Li, Hongli Du, Songyan Gao, Xin Dong, Hongbin Yua. Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism. Scientific reports. vol 7. 2018-10-15. PMID:28059131. |
our in vivo and in vitro studies show dioscin protects hippocampus from endotoxemia induced cascade neuro-inflammation through neurotransmitter 5-ht and hmgb-1/tlr4 signaling pathway, which accounts for the dioscin therapeutic effect in behavioral tests. |
2018-10-15 |
2023-08-13 |
Not clear |
| Saiful Alom Siddique, Thangavel Tamilselvan, Manikkannan Vishnupriya, Elumalai Balamuruga. Evaluation of Neurotransmitter Alterations in Four Distinct Brain Regions After Rapid Eye Movement Sleep Deprivation (REMSD) Induced Mania-Like Behaviour in Swiss Albino Mice. Neurochemical research. vol 43. issue 6. 2018-10-15. PMID:29671235. |
quantitative determinations of da, 5-ht, ne and gaba concentrations in four distinct brain regions (cerebral cortex, hippocampus, midbrain, and pons) were determined by the spectrofluorimetric method. |
2018-10-15 |
2023-08-13 |
mouse |