| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Kiedrowski, J Skangiel-Kramska, M Gradkowska, B Oderfeld-Nowa. Differential response of subtypes of 5-HT1 recognition sites in the rat hippocampus to partial denervation. Acta neurobiologiae experimentalis. vol 50. issue 4-5. 1991-11-13. PMID:2130643. |
[3h]5-ht uptake and [3h]5-ht binding to 5-ht1 receptor subtypes (5-ht1a and non-5-ht1a sites, having high and low affinity to spiperone, respectively) were studied in the rat hippocampus ten days after two types of electrocoagulative lesions. |
1991-11-13 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
effect of short- and long-term administration of lithium on the release of endogenous 5-ht in the hippocampus of the rat in vivo and in vitro. |
1991-11-06 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
the present study determined the effect of short- (3 days) and long- (21 days) term treatment with lithium on the release of 5-hydroxytryptamine (5-ht) form the hippocampus of the rat, measured both in vivo using microdialysis and in vitro using incubated slices. |
1991-11-06 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
in the in vivo experiments (on the chloral hydrate-anaesthetized rat) electrical stimulation of the dorsal raphe nucleus for 20 min evoked an increase of 5-ht in dialysates of hippocampus, which both lasted for the duration of the stimulus and was frequency-dependent (2-10 hz). |
1991-11-06 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
basal levels of 5-ht in hippocampal dialysates for rats receiving long- but not short-term treatment with lithium, were significantly lower than controls. |
1991-11-06 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
in agreement with the in vivo experiments, the in vitro experiments showed that depolarization (high potassium)-evoked release of endogenous 5-ht from slices of hippocampus of rats treated with short- but not long-term administration of lithium was enhanced compared to controls. |
1991-11-06 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, P Lambert, D G Grahame-Smit. Effect of short- and long-term administration of lithium on the release of endogenous 5-HT in the hippocampus of the rat in vivo and in vitro. Neuropharmacology. vol 30. issue 9. 1991-11-06. PMID:1922695. |
these experiments provide direct biochemical evidence that short-term treatment with lithium increases depolarization-evoked release of endogenous 5-ht in the hippocampus, an effect which may be related to the rapid antidepressant actions of the drug. |
1991-11-06 |
2023-08-11 |
rat |
| M E Montalbano, M Sabatino, M T Zagami, G Ferraro, G Caravaglios, N Vella, V La Grutt. Electrophysiological and microiontophoretic analysis of the habenulo-hippocampal circuit. Archives internationales de physiologie, de biochimie et de biophysique. vol 99. issue 3. 1991-11-05. PMID:1717065. |
moreover, in order to clarify the possible pathway involved in the habenulo-hippocampal circuit, the effects of iontophoretic acetylcholine and serotonin on hippocampal units were compared with those of habenular stimulation. |
1991-11-05 |
2023-08-11 |
cat |
| M E Montalbano, M Sabatino, M T Zagami, G Ferraro, G Caravaglios, N Vella, V La Grutt. Electrophysiological and microiontophoretic analysis of the habenulo-hippocampal circuit. Archives internationales de physiologie, de biochimie et de biophysique. vol 99. issue 3. 1991-11-05. PMID:1717065. |
iontophoretic atropine blocked the effects of acetylcholine ejection but did not antagonize stimulation effects; ion-tophoretic methysergide induced an increase of basal firing of hippocampal units and antagonized both serotonin and habenular stimulation inhibition. |
1991-11-05 |
2023-08-11 |
cat |
| X Li, B Zhao, H Ruan, H Li, Z Li. [Effect of intracerebral injection of substance P on serotonin contents of several brain regions and its relation with pain threshold, electroacupuncture analgesia in rats]. Zhen ci yan jiu = Acupuncture research. vol 16. issue 2. 1991-11-05. PMID:1717175. |
the purpose of this study is to observe the effect of intracerebroventricular (icv) and intra-pag injection of substance p (sp) on serotonin (5-ht) contents of hypothalamus, hippocampus, striatum and its relation with the change of pain threshold, electroacupuncture (ea) analgesia. |
1991-11-05 |
2023-08-11 |
rat |
| X Li, B Zhao, H Ruan, H Li, Z Li. [Effect of intracerebral injection of substance P on serotonin contents of several brain regions and its relation with pain threshold, electroacupuncture analgesia in rats]. Zhen ci yan jiu = Acupuncture research. vol 16. issue 2. 1991-11-05. PMID:1717175. |
the results were as follows: (1) after icv injection of sp, the pain threshold and the 5-ht contents of hypothalamus, hippocampus were significantly increased. |
1991-11-05 |
2023-08-11 |
rat |
| X Li, B Zhao, H Ruan, H Li, Z Li. [Effect of intracerebral injection of substance P on serotonin contents of several brain regions and its relation with pain threshold, electroacupuncture analgesia in rats]. Zhen ci yan jiu = Acupuncture research. vol 16. issue 2. 1991-11-05. PMID:1717175. |
after depletion of the 5-ht contents in brain by pcpa, the inhibitor of 5-ht synthesis, the effect of sp on elevating pain threshold and the 5-ht contents of hypothalamus, hippocampus were markedly attenuated, bud did not prevent the analgesic effect of sp (2) the pain threshold and the 5-ht contents of hypothalamus, hippocampus were dose-dependently increased by intra-pag injection of sp. |
1991-11-05 |
2023-08-11 |
rat |
| R Godbout, Y Chaput, P Blier, C de Montign. Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1681446. |
the depressant effects of microiontophoretically-applied tandospirone and 5-ht, on the firing activity of ca3 pyramidal neurones in the hippocampus were blocked by the intravenous injection of the 5-ht1a receptor antagonist, bmy-7378. |
1991-11-04 |
2023-08-11 |
rat |
| R Godbout, Y Chaput, P Blier, C de Montign. Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1681446. |
the sustained administration of tandospirone for 14 days (10 mg/kg/day, s.c.) altered neither the effectiveness of microiontophoretically-applied 5-ht and tandospirone nor that of endogenous 5-ht, released by the electrical simulation of the afferent 5-ht pathway, in suppressing the firing activity of pyramidal neurones in the hippocampus, suggesting that postsynaptic 5-ht1a receptors had not desensitized. |
1991-11-04 |
2023-08-11 |
rat |
| P Blier, O Curet, Y Chaput, C de Montign. Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--II. Effects of acute administration of 1-PP and long-term administration of tandospirone on noradrenergic neurotransmission. Neuropharmacology. vol 30. issue 7. 1991-11-04. PMID:1681447. |
reduced the effect of microiontophoretically-applied ne on ca3 pyramidal neurones of the dorsal hippocampus, without affecting their responsiveness to gaba and 5-ht. |
1991-11-04 |
2023-08-11 |
rat |
| C C Chen, J C Yan. Effects of short and long-lasting diabetes mellitus on mouse brain monoamines. Brain research. vol 552. issue 1. 1991-11-04. PMID:1913176. |
5-hydroxytryptamine concentration was increased in the hypothalamus, hippocampus, pons-medulla and cortex progressively from short-term to long-term diabetic mice. |
1991-11-04 |
2023-08-11 |
mouse |
| A M Laporte, L E Schechter, F J Bolaños, D Vergé, M Hamon, H Gozla. [3H]5-methyl-urapidil labels 5-HT1A receptors and alpha 1-adrenoceptors in the rat CNS. In vitro binding and autoradiographic studies. European journal of pharmacology. vol 198. issue 1. 1991-10-31. PMID:1680714. |
serotonin and prazosin inhibited [3h]5-methyl-urapidil binding to membranes from the rat hippocampus, cerebral cortex and brainstem biphasically, leading to the definition of serotonin high-affinity and prazosin high-affinity [3h]5-methyl-urapidil binding sites. |
1991-10-31 |
2023-08-11 |
rat |
| T J Feuerstein, E Neuschwander, W Sauermann, A Lup. The conditions of Ca2+ entry via L-type channels for induction of serotonin release from rabbit hippocampus. European journal of pharmacology. vol 198. issue 1. 1991-10-31. PMID:1717292. |
the conditions of ca2+ entry via l-type channels for induction of serotonin release from rabbit hippocampus. |
1991-10-31 |
2023-08-11 |
rabbit |
| T J Feuerstein, E Neuschwander, W Sauermann, A Lup. The conditions of Ca2+ entry via L-type channels for induction of serotonin release from rabbit hippocampus. European journal of pharmacology. vol 198. issue 1. 1991-10-31. PMID:1717292. |
the l-type voltage-sensitive calcium channel (vscc) agonists of the dihydropyridine (dhp) type, bay k 8644 and (+)-202-791, concentration dependently enhanced the k+ (26.2 mm)-induced 5-ht release from slices of rabbit hippocampus prelabelled with [3h]5-ht when the slices were treated with the monoamine oxidase (mao) inhibitor, pargyline. |
1991-10-31 |
2023-08-11 |
rabbit |
| M Johnson, G R Hanson, J W Gib. Norepinephrine does not contribute to methamphetamine-induced changes in hippocampal serotonergic system. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1717871. |
the reduction in serotonin (5-ht) in the hippocampus induced by methamphetamine, was not altered by the treatment with dsp4. |
1991-10-31 |
2023-08-11 |
rat |