| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dresse, J Scuvée-Moreau, E Mocaaër, J C Poignan. [Contribution of electrophysiology to the study of tianeptine and other antidepressive agents]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836612. |
iontophoretic application of tianeptine does not affect the response of pyramidal cells in the hippocampus to application of serotonin or gamma amino-butyric acid (gaba), but lowers recovery time after iontophoretic administration of serotonin or gaba. |
1992-01-30 |
2023-08-11 |
Not clear |
| C Moret, M Brile. Platelet 3H-paroxetine binding to the serotonin transporter is insensitive to changes in central serotonergic innervation in the rat. Psychiatry research. vol 38. issue 2. 1992-01-28. PMID:1836639. |
fifteen days after the intracerebroventricular administration of 5,7-dihydroxytryptamine (250 micrograms/animal) to rats to lesion central serotonergic neurons, serotonergic innervation was reduced by 82% in the cortex and 98% in the hippocampus as determined by endogenous serotonin levels. |
1992-01-28 |
2023-08-11 |
rat |
| K M Dewar, L Grondin, M Carli, L Lima, T A Reade. [3H]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment. Journal of neurochemistry. vol 58. issue 1. 1992-01-22. PMID:1370077. |
[3h]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment. |
1992-01-22 |
2023-08-11 |
rat |
| K M Dewar, L Grondin, M Carli, L Lima, T A Reade. [3H]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment. Journal of neurochemistry. vol 58. issue 1. 1992-01-22. PMID:1370077. |
furthermore, [3h]paroxetine binding and tissue concentrations of 5-ht and 5-hiaa were measured in the following different regions of the rat brain: cingulate, parietal, and visual cortical areas; dorsal and ventral hippocampus; rostral and caudal halves of neostriatum; ventral mesencephalic tegmentum; and midbrain raphe nuclei region after administration of pcpa, pca, or saline vehicle. |
1992-01-22 |
2023-08-11 |
rat |
| J Sharkey, D E McBean, P A Kell. Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy"). Psychopharmacology. vol 105. issue 1. 1992-01-13. PMID:1684057. |
in the same rats [3h]-paroxetine binding autoradiography revealed heterogeneity in the regional distribution of 5-ht uptake site depletion within neocortex (0-92%) and hippocampus (30-95%). |
1992-01-13 |
2023-08-11 |
rat |
| J Sharkey, D E McBean, P A Kell. Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy"). Psychopharmacology. vol 105. issue 1. 1992-01-13. PMID:1684057. |
this study provides direct evidence that the loss of 5-ht innervation caused by exposure to mdma results in lasting functional changes in hippocampus. |
1992-01-13 |
2023-08-11 |
rat |
| M A Wogar, C M Bradshaw, E Szabad. Evidence for an involvement of 5-hydroxytryptaminergic neurones in the maintenance of operant behaviour by positive reinforcement. Psychopharmacology. vol 105. issue 1. 1992-01-13. PMID:1720896. |
the levels of 5ht and 5-hydroxyindoleacetic acid in the parietal cortex, hippocampus, nucleus accumbens and hypothalamus were markedly reduced in all four regions in the lesioned group, but the levels of noradrenaline and dopamine were not significantly affected. |
1992-01-13 |
2023-08-11 |
rat |
| J R Seckl, G Fin. Use of in situ hybridization to investigate the regulation of hippocampal corticosteroid receptors by monoamines. The Journal of steroid biochemistry and molecular biology. vol 40. issue 4-6. 1992-01-08. PMID:1659890. |
the hippocampus receives major noradrenergic and serotoninergic (5-ht) innervations which interact with corticosteroid-sensitive cells. |
1992-01-08 |
2023-08-11 |
rat |
| J R Seckl, G Fin. Use of in situ hybridization to investigate the regulation of hippocampal corticosteroid receptors by monoamines. The Journal of steroid biochemistry and molecular biology. vol 40. issue 4-6. 1992-01-08. PMID:1659890. |
investigation of the effects of 5,7-dihydroxytryptamine lesions of 5-ht neurons showed significantly reduced gr and mr mrna expression in some hippocampal subregions. |
1992-01-08 |
2023-08-11 |
rat |
| S Oleskevich, L Descarries, K C Watkins, P Séguéla, A Daszut. Ultrastructural features of the serotonin innervation in adult rat hippocampus: an immunocytochemical description in single and serial thin sections. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956515. |
ultrastructural features of the serotonin innervation in adult rat hippocampus: an immunocytochemical description in single and serial thin sections. |
1992-01-02 |
2023-08-11 |
rat |
| S Oleskevich, L Descarries, K C Watkins, P Séguéla, A Daszut. Ultrastructural features of the serotonin innervation in adult rat hippocampus: an immunocytochemical description in single and serial thin sections. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956515. |
this study was aimed at characterizing the fine-structural features of the normal serotonin (5-ht) innervation in adult rat hippocampus, by means of electron microscopic immunocytochemistry with a polyclonal antiserum against 5-ht-glutaraldehyde-protein conjugate (donated by michel geffard, bordeaux). |
1992-01-02 |
2023-08-11 |
rat |
| S Oleskevich, L Descarries, K C Watkins, P Séguéla, A Daszut. Ultrastructural features of the serotonin innervation in adult rat hippocampus: an immunocytochemical description in single and serial thin sections. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956515. |
as measured in single sections, hippocampal 5-ht varicosities were of comparable diameter (0.57 microns on the average) in the two anatomical sectors and four neuropil layers examined. |
1992-01-02 |
2023-08-11 |
rat |
| A Daszuta, G Chazal, S Garcia, S Oleskevich, L Descarrie. Ultrastructural features of serotonin neurons grafted to adult rat hippocampus: an immunocytochemical analysis of their cell bodies and axon terminals. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956516. |
ultrastructural features of serotonin neurons grafted to adult rat hippocampus: an immunocytochemical analysis of their cell bodies and axon terminals. |
1992-01-02 |
2023-08-11 |
rat |
| A Daszuta, G Chazal, S Garcia, S Oleskevich, L Descarrie. Ultrastructural features of serotonin neurons grafted to adult rat hippocampus: an immunocytochemical analysis of their cell bodies and axon terminals. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956516. |
serotonin (5-ht) immunocytochemistry was used at the electron microscopic level to examine 5-ht neurons reinnervating and hyperinnervating the hippocampus of adult rat, three to four months after a total 5-ht denervation and subsequent graft of embryonic raphe cells. |
1992-01-02 |
2023-08-11 |
rat |
| A Daszuta, G Chazal, S Garcia, S Oleskevich, L Descarrie. Ultrastructural features of serotonin neurons grafted to adult rat hippocampus: an immunocytochemical analysis of their cell bodies and axon terminals. Neuroscience. vol 42. issue 3. 1992-01-02. PMID:1956516. |
the similarity between the respective microenvironments of the supernumerary, graft-borne 5-ht terminals and of their normal counterparts could only be explained by a random intratissular distribution of these varicosities in both the normal and the grafted hippocampus. |
1992-01-02 |
2023-08-11 |
rat |
| J H Trouvin, M C Maubrey, H Raynal, C Jacquo. Effect of L-dopa loading on 5-HTP decarboxylation in rat brain areas. Fundamental & clinical pharmacology. vol 5. issue 6. 1991-12-30. PMID:1720112. |
the time course of 5-hydroxytryptophan (5-htp), serotonin (5-ht), and 5-hydroxyindoleacetic acid (5-hiaa) concentrations in four rat brain areas (hypothalamus, hippocampus, striatum and olfactory bulbs) were investigated after treatment with l-dopa (125 mg/kg, ip) + benserazide (50 mg/kg, ip). |
1991-12-30 |
2023-08-11 |
rat |
| S Hjort. Single-dose 8-OH-DPAT pretreatment does not induce tachyphylaxis to the 5-HT release-reducing effect of 5-HT1A autoreceptor agonists. European journal of pharmacology. vol 199. issue 2. 1991-12-30. PMID:1835441. |
the results show that single-dose pretreatment with the reference 5-ht1a receptor agonist 8-hydroxy-2-(din-propylamino)tetralin, 8-oh-dpat, (i) did not significantly alter the baseline output of 5-ht in the rat ventral hippocampus 24 h later, and (ii) did not alter the release-reducing response to 5-ht1a agonist (8-oh-dpat, ipsapirone or bmy 7378) challenge under the same conditions. |
1991-12-30 |
2023-08-11 |
rat |
| K A Dillon, R Gross-Isseroff, M Israeli, A Biego. Autoradiographic analysis of serotonin 5-HT1A receptor binding in the human brain postmortem: effects of age and alcohol. Brain research. vol 554. issue 1-2. 1991-12-26. PMID:1834306. |
quantitative autoradiographic analysis of serotonin 5-ht1a receptors in the human brain, using [3h]8-oh-dpat as a ligand, reveals region-specific decreases in receptor labeling with age in several cortical and hippocampal regions and in the raphe nuclei. |
1991-12-26 |
2023-08-11 |
human |
| B Robertson, G B Baker, C H Vanderwol. The effects of serotonergic stimulation on hippocampal and neocortical slow waves and behavior. Brain research. vol 555. issue 2. 1991-12-23. PMID:1933339. |
in all rats, scopolamine-resistant hippocampal rhythmical slow activity (rsa), thought to be dependent on brain serotonin, maintained its normal relation to behavior, occurring in close correlation with type 1 behaviors (postural changes, turning of the head, walking). |
1991-12-23 |
2023-08-11 |
rat |
| B Robertson, G B Baker, C H Vanderwol. The effects of serotonergic stimulation on hippocampal and neocortical slow waves and behavior. Brain research. vol 555. issue 2. 1991-12-23. PMID:1933339. |
it was concluded that increased serotonergic activity in the cns causes an increase in motor activity and a correlated increase in scopolamine-resistant hippocampal rsa and scopolamine-resistant neocortical lvfa and suggested that metergoline blocks serotonin receptors mediating stereotyped behaviors, thereby permitting the expression of serotonin-mediated locomotion. |
1991-12-23 |
2023-08-11 |
rat |