| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Johnson, G R Hanson, J W Gib. Norepinephrine does not contribute to methamphetamine-induced changes in hippocampal serotonergic system. Neuropharmacology. vol 30. issue 6. 1991-10-31. PMID:1717871. |
the pretreatment with dsp4 also failed to block the decline in activity of tph in the hippocampus or concentrations of 5-ht measured 18 hr after the last of 4 doses of methamphetamine (15 mg/kg, s.c.). |
1991-10-31 |
2023-08-11 |
rat |
| P Van den Hooff, M Galva. Electrophysiology of the 5-HT1A ligand MDL 73005EF in the rat hippocampal slice. European journal of pharmacology. vol 196. issue 3. 1991-10-24. PMID:1893914. |
the actions of 5-hydroxytryptamine (5-ht) and the 5-ht1a receptor ligand mdl 73005ef on neuronal activity in the ca1 region of rat hippocampal slices in vitro were recorded using intra- and extracellular recording techniques. |
1991-10-24 |
2023-08-11 |
rat |
| M E Newman, A Ben-Zeev, B Lere. Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. European journal of pharmacology. vol 207. issue 3. 1991-10-22. PMID:1654266. |
chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. |
1991-10-22 |
2023-08-11 |
rat |
| M E Newman, A Ben-Zeev, B Lere. Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. European journal of pharmacology. vol 207. issue 3. 1991-10-22. PMID:1654266. |
on two occasions) to rats resulted in a severe depletion of [3h]paroxetine binding sites, a measure of presynaptic serotonergic terminals, in both cortex and hippocampus, but did not affect [3h]8-hydroxy-2-(di-n-propylamino)tetralin [( 3h]8-oh-dpat) binding or 5-hydroxytryptamine (5-ht)-induced inhibition of forskolin-stimulated adenylate cyclase in hippocampal membranes. |
1991-10-22 |
2023-08-11 |
rat |
| M E Newman, A Ben-Zeev, B Lere. Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus. European journal of pharmacology. vol 207. issue 3. 1991-10-22. PMID:1654266. |
for 2 weeks) or lithium (0.2% for 2 weeks) to pca-treated rats did not affect [3h]8-oh-dpat binding but reduced the degree of inhibition of forskolin-stimulated adenylate cyclase by 5-ht in hippocampal membranes. |
1991-10-22 |
2023-08-11 |
rat |
| W A Wolf, E Ziaja, R A Arthur, P Z Anastasiadis, R A Levine, D M Kuh. Effect of tetrahydrobiopterin on serotonin synthesis, release, and metabolism in superfused hippocampal slices. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1716662. |
effect of tetrahydrobiopterin on serotonin synthesis, release, and metabolism in superfused hippocampal slices. |
1991-10-21 |
2023-08-11 |
rat |
| W A Wolf, E Ziaja, R A Arthur, P Z Anastasiadis, R A Levine, D M Kuh. Effect of tetrahydrobiopterin on serotonin synthesis, release, and metabolism in superfused hippocampal slices. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1716662. |
the effects of 6r-5,6,7,8-tetrahydro-l-biopterin (6r-bh4), the in vivo cofactor for tryptophan hydroxylase, on the synthesis, release, and metabolism of serotonin were studied in superfused slices from rat hippocampus. |
1991-10-21 |
2023-08-11 |
rat |
| W A Wolf, E Ziaja, R A Arthur, P Z Anastasiadis, R A Levine, D M Kuh. Effect of tetrahydrobiopterin on serotonin synthesis, release, and metabolism in superfused hippocampal slices. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1716662. |
under the same incubation conditions, 6r-bh4 altered neither the synthesis (basal or tryptophan-stimulated) nor the metabolism of serotonin in hippocampal slices. |
1991-10-21 |
2023-08-11 |
rat |
| M G Van Luijtelaar, J A Tonnaer, A L Frankhuijzen, H Dijkstra, J J Hagan, H W Steinbusc. Morphological, neurochemical, and behavioral studies on serotonergic denervation and graft-induced reinnervation of the rat hippocampus. Neuroscience. vol 42. issue 2. 1991-10-21. PMID:1716745. |
the turnover of 5-hydroxytryptamine in both the denervated and the reinnervated hippocampus was comparable to that in control tissue. |
1991-10-21 |
2023-08-11 |
rat |
| A J Baker, M H Zornow, M S Scheller, T L Yaksh, S R Skilling, D H Smullin, A A Larson, R Kuczensk. Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain. Journal of neurochemistry. vol 57. issue 4. 1991-10-21. PMID:1895110. |
accordingly, this study was undertaken to examine the patterns of changes of extracellular glutamate, aspartate, glycine concentrations in the hippocampus, and dopamine, serotonin, and dopamine metabolites in the caudate nucleus with varying durations (5, 10, or 15 minutes) of transient global cerebral ischemia as evidence to support their pathogenetic roles. |
1991-10-21 |
2023-08-11 |
rabbit |
| S E File, P S Mabbutt, N Andrew. Diazepam withdrawal responses measured in the social interaction test of anxiety and their reversal by baclofen. Psychopharmacology. vol 104. issue 1. 1991-09-30. PMID:1882005. |
possible sites of action mediating these effects of baclofen are discussed, and it is suggested that either post-synaptic gabab sites in the hippocampus are involved or that the reversal of the decreased social interaction detected on withdrawal of diazepam treatment is due to a baclofen-mediated inhibition of 5-ht release in the hippocampus. |
1991-09-30 |
2023-08-11 |
rat |
| T Akai, M Takahashi, Y Nakada, R Ohnishi, Y Ikoma, M Yamaguch. [Anxiolytic effects of lisuride and its agonistic action to central 5-HT1A receptors]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 97. issue 4. 1991-09-24. PMID:1678728. |
inhibitory effects of lisuride on bindings of [3h]8-oh-dpat in the hippocampus was almost the same as that of 5-ht (ki = 0.5 nm) and stronger than those of the 5-ht agonist 5-meo-dmt (ki = 2.1 nm) or other ergot derivatives (bromocriptine and pergolide, ki = 3.0 nm). |
1991-09-24 |
2023-08-11 |
rat |
| R Alonso, P Soubri. Effects of serotonergic denervation on the density and plasticity of brain muscarinic receptors in the rat. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1714634. |
intracerebroventricular injection of 5,7-dihydroxytryptamine (5,7-dht) in rats produced a 90% reduction in cortical and hippocampal 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) contents. |
1991-09-16 |
2023-08-11 |
rat |
| R Alonso, P Soubri. Effects of serotonergic denervation on the density and plasticity of brain muscarinic receptors in the rat. Synapse (New York, N.Y.). vol 8. issue 1. 1991-09-16. PMID:1714634. |
these results suggest 1) that 5-ht denervation did not affect the density and sensitivity of muscarinic receptors and 2) that the ability of cortical and hippocampal non-m1 receptors to up-regulate following repeated injection of scopolamine requires the integrity of 5-ht neurons terminating in these brain structures. |
1991-09-16 |
2023-08-11 |
rat |
| C L Ehlers, T L Wall, R I Chapli. Long latency event-related potentials in rats: effects of dopaminergic and serotonergic depletions. Pharmacology, biochemistry, and behavior. vol 38. issue 4. 1991-09-16. PMID:1831273. |
pcpa produced a 50% depletion of serotonin concomitant with significant reductions in the negative components in the 50-100 ms range recorded in hippocampus and cortex. |
1991-09-16 |
2023-08-11 |
rat |
| R M Kessler, M S Ansari, D E Schmidt, T de Paulis, J A Clanton, R Innis, M al-Tikriti, R G Manning, D Gillespi. High affinity dopamine D2 receptor radioligands. 2. [125I]epidepride, a potent and specific radioligand for the characterization of striatal and extrastriatal dopamine D2 receptors. Life sciences. vol 49. issue 8. 1991-09-12. PMID:1830917. |
the ic50's for inhibition of [125i]epidepride binding to striatal, medial frontal cortical, and hippocampal membranes for sch 23390, skf 83566, serotonin, ketanserin, mianserin, naloxone, qnb, prasozin, clonidine, alprenolol, and norepinephrine ranged from 1 microm to greater than 10 microm. |
1991-09-12 |
2023-08-11 |
rat |
| Y Kataoka, K Shibata, A Miyazaki, Y Inoue, K Tominaga, S Koizumi, S Ueki, M Niw. Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic. Neuropharmacology. vol 30. issue 5. 1991-09-11. PMID:1865994. |
the effect of tandospirone, a 5-hydroxytryptamine (5-ht)1a agonist/anxiolytic, injected directly into dorsal hippocampus, on vogel-type conflict behavior in rats was investigated and the findings were compared with the effects of diazepam and zopiclone. |
1991-09-11 |
2023-08-11 |
rat |
| H Tamir, K P Liu, S C Hsiung, P Y Yu, A L Kirchgessner, M D Gersho. Identification of serotonin receptors recognized by anti-idiotypic antibodies. Journal of neurochemistry. vol 57. issue 3. 1991-09-04. PMID:1861158. |
the anti-idiotypic antibodies antagonized the binding of [3h]5-ht to membranes isolated from the cerebral cortex, striatum, and raphe area more than to membranes from hippocampus or cerebellum. |
1991-09-04 |
2023-08-11 |
Not clear |
| A Mørk, A Geisle. Tosyl-lysyl chloromethylketone inactivation of adenylate cyclase in separate regions of the rat brain. Archives internationales de physiologie, de biochimie et de biophysique. vol 99. issue 2. 1991-08-30. PMID:1713500. |
in the cortex and hippocampus this action of tlck was found also in the presence of isoprenaline and 5-ht, respectively. |
1991-08-30 |
2023-08-11 |
rat |
| I Kusumi, M Mikuni, K Takahash. Effect of subchronic antidepressants administration on serotonin-stimulated phosphoinositide hydrolysis in para-chlorophenylalanine-treated rat hippocampal slices. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 3. 1991-08-30. PMID:1713698. |
this study examines the effect of subchronic parachlorophenylalanine (pcpa) treatment upon serotonin (5-ht)-stimulated inositol monophosphate (ip-1) accumulation in rat hippocampal slices and also the effect of antidepressants upon this 5-ht response in the hippocampus from rats treated with or without concurrent administration of pcpa. |
1991-08-30 |
2023-08-11 |
rat |