| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gobbi, S Cavanus, A Miari, T Mennin. Effect of acute and chronic administration of buspirone on serotonin and benzodiazepine receptor subtypes in the rat brain: an autoradiographic study. Neuropharmacology. vol 30. issue 4. 1991-08-20. PMID:1649418. |
the results confirmed that buspirone is a selective 5-ht1a ligand, since it inhibited the binding of [3h]5-ht with lower ic50 values (about 100 nm) in regions of the brain of the rat where this receptor subtype is predominant (such as hippocampal areas). |
1991-08-20 |
2023-08-11 |
rat |
| T Mennini, A Miar. Modulation of [3H]-glutamate binding by serotonin in the rat hippocampus: an autoradiographic study. Life sciences. vol 49. issue 4. 1991-08-20. PMID:1677153. |
modulation of [3h]-glutamate binding by serotonin in the rat hippocampus: an autoradiographic study. |
1991-08-20 |
2023-08-11 |
rat |
| T Mennini, A Miar. Modulation of [3H]-glutamate binding by serotonin in the rat hippocampus: an autoradiographic study. Life sciences. vol 49. issue 4. 1991-08-20. PMID:1677153. |
serotonin (5-ht) added in vitro (10 microm) increased [3h]-glutamate specific binding in the rat hippocampus, reaching statistical significance in layers rich in n-methyl-d-aspartate sensitive glutamate receptors. |
1991-08-20 |
2023-08-11 |
rat |
| T Mennini, A Miar. Modulation of [3H]-glutamate binding by serotonin in the rat hippocampus: an autoradiographic study. Life sciences. vol 49. issue 4. 1991-08-20. PMID:1677153. |
two days after lesion of serotonergic afferents to the hippocampus with 5,7-dihydroxytryptamine [3h]-glutamate binding was significantly decreased in the ca3 region and stratum lacunosum moleculare of the hippocampus, this reduction being reversed by in vitro addition of 10 microm 5-ht. |
1991-08-20 |
2023-08-11 |
rat |
| J H Harin. Reorganization of the area dentata serotoninergic plexus after lesions of the median raphe nucleus. The Journal of comparative neurology. vol 306. issue 4. 1991-08-19. PMID:1712795. |
hippocampal serotonin concentration and serotonin high affinity uptake are also significantly reduced. |
1991-08-19 |
2023-08-11 |
Not clear |
| B Söderpalm, J A Enge. Involvement of the GABAA/benzodiazepine chloride ionophore receptor complex in the 5,7-DHT Induced anticonflict effect. Life sciences. vol 49. issue 2. 1991-08-02. PMID:1676482. |
the 5,7-dht treatment produced marked depletions of 5-ht in the limbic system (80-90%) and hippocampus (90-95%), and an increase in the 5-hiaa/5-ht quotient in hippocampus. |
1991-08-02 |
2023-08-11 |
rat |
| A Karschin, B Y Ho, C Labarca, O Elroy-Stein, B Moss, N Davidson, H A Leste. Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 13. 1991-08-02. PMID:1905814. |
serotonin type 1a receptors may activate a similar pathway in hippocampal neurons. |
1991-08-02 |
2023-08-11 |
human |
| C Sotel. Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation. Brain research. vol 541. issue 2. 1991-08-01. PMID:2054644. |
by 40 days, the pattern of 5-ht hippocampal innervation is restored but its density is still lower than in controls. |
1991-08-01 |
2023-08-11 |
rat |
| J Miguez, F Martin, M Aldegund. Differential effects of pinealectomy on amygdala and hippocampus serotonin metabolism. Journal of pineal research. vol 10. issue 2. 1991-07-31. PMID:1711579. |
differential effects of pinealectomy on amygdala and hippocampus serotonin metabolism. |
1991-07-31 |
2023-08-11 |
rat |
| J Miguez, F Martin, M Aldegund. Differential effects of pinealectomy on amygdala and hippocampus serotonin metabolism. Journal of pineal research. vol 10. issue 2. 1991-07-31. PMID:1711579. |
the purpose of the present study was to determine the effects of long-term pinealectomy on serotonin metabolism in the amygdala and the hippocampus of male rats. |
1991-07-31 |
2023-08-11 |
rat |
| J Miguez, F Martin, M Aldegund. Differential effects of pinealectomy on amygdala and hippocampus serotonin metabolism. Journal of pineal research. vol 10. issue 2. 1991-07-31. PMID:1711579. |
pinealectomy did not significantly alter either tryptophan or serotonin concentrations in the amygdala or the hippocampus. |
1991-07-31 |
2023-08-11 |
rat |
| K L Jansen, R L Faull, M Dragunow, B L Syne. Alzheimer's disease: changes in hippocampal N-methyl-D-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors--an autoradiographic study. Neuroscience. vol 39. issue 3. 1991-07-23. PMID:1965859. |
alzheimer's disease: changes in hippocampal n-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors--an autoradiographic study. |
1991-07-23 |
2023-08-11 |
Not clear |
| T Sharp, S R Bramwell, D G Grahame-Smit. Release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis: sensitivity to tetrodotoxin, calcium and calcium antagonists. Neuroscience. vol 39. issue 3. 1991-07-23. PMID:2097517. |
release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis: sensitivity to tetrodotoxin, calcium and calcium antagonists. |
1991-07-23 |
2023-08-11 |
rat |
| T Sharp, S R Bramwell, D G Grahame-Smit. Release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis: sensitivity to tetrodotoxin, calcium and calcium antagonists. Neuroscience. vol 39. issue 3. 1991-07-23. PMID:2097517. |
a dialysis probe was implanted into the ventral hippocampus and continuously perfused with artificial cerebrospinal fluid containing the selective 5-hydroxytryptamine uptake inhibitor citalopram (1 microm). |
1991-07-23 |
2023-08-11 |
rat |
| T Nishikawa, B Scatton, T Enomoto, K Shinohara, K Takahash. Modulation of striatal serotonin metabolism by baclofen, a gamma-aminobutyric acidB receptor agonist. The Tokai journal of experimental and clinical medicine. vol 14. issue 5-6. 1991-07-22. PMID:2562298. |
failed to modify the rate of serotonin (5-ht) disappearance during inhibition of tryptophan hydroxylase in the striatum and hippocampus. |
1991-07-22 |
2023-08-11 |
Not clear |
| C M Fattaccini, H Gozlan, M Hamo. Differential effects of d-fenfluramine and p-chloroamphetamine on H75/12-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain. Neuropharmacology. vol 30. issue 1. 1991-07-17. PMID:1710793. |
both drugs (0.5-5.0 mg/kg i.p., 2 hr before death) produced a dose-dependent reduction in levels of 5-ht, but only p-chloroamphetamine decreased the levels of 5-hydroxyindoleacetic acid (5-hiaa) in the hippocampus, striatum and cerebral cortex. |
1991-07-17 |
2023-08-11 |
rat |
| P S Whitton, G S Sarna, M T O'Connell, G Curzo. The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. Neuropharmacology. vol 30. issue 1. 1991-07-17. PMID:2046875. |
the effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. |
1991-07-17 |
2023-08-11 |
rat |
| P S Whitton, G S Sarna, M T O'Connell, G Curzo. The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. Neuropharmacology. vol 30. issue 1. 1991-07-17. PMID:2046875. |
), whether given as a single dose or as daily doses for 14 days, attenuated the k(+)-evoked rise of extracellular 5-ht in the hippocampus in vivo. |
1991-07-17 |
2023-08-11 |
rat |
| P S Whitton, G S Sarna, M T O'Connell, G Curzo. The effect of the novel antidepressant tianeptine on the concentration of 5-hydroxytryptamine in rat hippocampal dialysates in vivo. Neuropharmacology. vol 30. issue 1. 1991-07-17. PMID:2046875. |
), given acutely, did not reduce basal levels of 5-ht in hippocampal dialysates in the presence of the 5-ht reuptake inhibitor, citalopram. |
1991-07-17 |
2023-08-11 |
rat |
| S C Cheetham, M R Crompton, C L Katona, R W Horto. Brain 5-HT1 binding sites in depressed suicides. Psychopharmacology. vol 102. issue 4. 1991-07-17. PMID:2096412. |
the present results, together with our previous studies, provide no evidence of altered cortical 5-ht markers in depressed suicides, but further emphasise abnormalities in the hippocampus. |
1991-07-17 |
2023-08-11 |
Not clear |