| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Uphouse, K Eckols, D Croissant, G Stewar. Serotonergic changes following proestrous treatment with p,p'-DDT. Neurotoxicology. vol 11. issue 3. 1991-03-18. PMID:1704493. |
p,p'-ddt decreased the level of 5-ht in frontal cortex and hippocampus. |
1991-03-18 |
2023-08-11 |
rat |
| L I Kramarova, T F Lee, Y Cui, L C Wan. State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]-enkephalin on hippocampal serotonin release in ground squirrels. Life sciences. vol 48. issue 2. 1991-03-15. PMID:1847226. |
state-dependent variation in the inhibitory effect of [d-ala2, d-leu5]-enkephalin on hippocampal serotonin release in ground squirrels. |
1991-03-15 |
2023-08-11 |
Not clear |
| L I Kramarova, T F Lee, Y Cui, L C Wan. State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]-enkephalin on hippocampal serotonin release in ground squirrels. Life sciences. vol 48. issue 2. 1991-03-15. PMID:1847226. |
the seasonal change of [d-ala2, d-leu5]-enkephalin (dadle), a delta receptor agonist, in modulating k+ (35 mm)-induced [3h]-5-hydroxytryptamine (5-ht) release from the hippocampal and hypothalamic slices of euthermic and hibernating richardsons' ground squirrels was therefore investigated. |
1991-03-15 |
2023-08-11 |
Not clear |
| L I Kramarova, T F Lee, Y Cui, L C Wan. State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]-enkephalin on hippocampal serotonin release in ground squirrels. Life sciences. vol 48. issue 2. 1991-03-15. PMID:1847226. |
dadle (0.1-10 microm) had no effect on 5-ht release in the hypothalamic slices but elicited a dose-related inhibition on [3h]-5-ht release from the hippocampal slices of the euthermic ground squirrel. |
1991-03-15 |
2023-08-11 |
Not clear |
| L I Kramarova, T F Lee, Y Cui, L C Wan. State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]-enkephalin on hippocampal serotonin release in ground squirrels. Life sciences. vol 48. issue 2. 1991-03-15. PMID:1847226. |
in contrast, dadle failed to alter the k(+)-induced 5-ht release from the hippocampal slices of the hibernating ground squirrel. |
1991-03-15 |
2023-08-11 |
Not clear |
| J Aguilera, L A López, F González-Sastr. Stereotaxic injection of tetanus toxin in rat central nervous system causes alteration in normal levels of monoamines. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1993891. |
because direct stereotaxic injections of the toxin in the hypothalamus or hippocampus produced significant serotonin increases in both areas, it is proposed that tetanus toxin interacts with presynaptic targets to produce serotonin accumulation; this is probably due in part to an activation of tryptophan 5-hydroxylase. |
1991-03-15 |
2023-08-11 |
rat |
| F S Messih. Effect of methionine on regional CDF-1 mouse brain monoamines. Drug and chemical toxicology. vol 13. issue 4. 1991-03-12. PMID:2279463. |
the results suggest methionine-mediated decreases of dopamine turnover in the hippocampus and medulla compared to increases of serotonin turnover in the cerebral cortex and midbrain regions. |
1991-03-12 |
2023-08-11 |
mouse |
| J H Williams, J R Meara, E C Azmiti. Effects of 5,7-dihydroxytryptamine injections in the fornix-fimbria on locomotor activity in photocell cages and the open field. Behavioural brain research. vol 40. issue 1. 1991-03-08. PMID:2278655. |
microinjections of 5,7-dihydroxytryptamine (5,7-dht) into the fornix-fimbria (ff) reduced dorsal hippocampal [3]5-ht uptake to 40% of control levels. |
1991-03-08 |
2023-08-11 |
Not clear |
| J H Williams, J R Meara, E C Azmiti. Effects of 5,7-dihydroxytryptamine injections in the fornix-fimbria on locomotor activity in photocell cages and the open field. Behavioural brain research. vol 40. issue 1. 1991-03-08. PMID:2278655. |
hence ff-derived hippocampal 5-ht terminals participate in controlling activity, but their role depends on the test apparatus and procedures. |
1991-03-08 |
2023-08-11 |
Not clear |
| T Hashimoto, N Nishino, H Nakai, C Tanak. Increase in serotonin 5-HT1A receptors in prefrontal and temporal cortices of brains from patients with chronic schizophrenia. Life sciences. vol 48. issue 4. 1991-03-05. PMID:1824956. |
the [3h]8-oh-dpat bindings to the prefrontal cortex and hippocampus were potently inhibited by serotonin (ic50 = 6.3 x 10(-9) m) and 5-ht1a agonists (ic50 = 5.0 x 10(-9) - 2.3 x 10(-7) m), while other neurotransmitters, 5-ht2 and 5-ht3 related compounds did not inhibit the binding (ic50 greater than 10(-5) m). |
1991-03-05 |
2023-08-11 |
human |
| G Freeman, T Sobotka, D Hatta. Acute effects of aspartame on concentrations of brain amines and their metabolites in selected brain regions of Fischer 344 and Sprague-Dawley rats. Drug and chemical toxicology. vol 13. issue 2-3. 1991-03-01. PMID:1703475. |
regional brain concentrations of norepinephrine (ne), dopamine (da), serotonin (5-ht) and their metabolites were analyzed in the hypothalamus, cerebellum, pons/medulla, hippocampus, striatum, cortex, and midbrain/thalamus at 30, 60, 120, or 240 min after oral aspartame (1000 mg/kg) administration. |
1991-03-01 |
2023-08-11 |
rat |
| A Valjakka, J Sirviö, A Pitkänen, P J Riekkine. Brain amines and neocortical EEG in young and aged rats. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 96. issue 2. 1991-03-01. PMID:1980441. |
the levels of monoamines, serotonin and their metabolites were measured from the frontal cortex, parieto-occipital cortex, hippocampus, brainstem and midbrain. |
1991-03-01 |
2023-08-11 |
rat |
| A Adell, A Carceller, F Artiga. Regional distribution of extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the brain of freely moving rats. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1703223. |
the extracellular concentrations of 5-hydroxytryptamine (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) have been determined in six brain areas of awake rats (frontal cortex, striatum, hypothalamus, hippocampus, inferior colliculus, and raphe nuclei) using intracerebral microdialysis. |
1991-02-26 |
2023-08-11 |
rat |
| B Earley, M Burke, B E Leonard, C J Gouret, J L Junie. A comparison of the psychopharmacological profiles of phencyclidine, ketamine and (+) SKF 10,047 in the trimethyltin rat model. Neuropharmacology. vol 29. issue 8. 1991-02-25. PMID:1980347. |
noradrenaline, dopamine, serotonin and 5-hydroxindole 3-acetic acid), examined in the amygdaloid cortex and hippocampal regions, while ketamine increased the steady state concentrations of 5-hiaa in the amygdaloid cortex. |
1991-02-25 |
2023-08-11 |
rat |
| C Bendotti, A Servadio, G Forloni, N Angeretti, R Samani. Increased tryptophan hydroxylase mRNA in raphe serotonergic neurons spared by 5,7-dihydroxytryptamine. Brain research. Molecular brain research. vol 8. issue 4. 1991-02-19. PMID:2176712. |
five days after the intracerebroventricular injection of 5,7-dihydroxytryptamine (5,7-dht), which markedly reduced the serotonin (5-ht) content in the hippocampus, caudate putamen and cortex, the hybridization signal had completely disappeared in the dorsal region of the ndr. |
1991-02-19 |
2023-08-11 |
rat |
| A H Tiong, J S Richardso. The characterization of beta adrenoceptor subtypes in the rat amygdala and hippocampus. The International journal of neuroscience. vol 54. issue 3-4. 1991-02-12. PMID:1979972. |
to get an accurate estimate of beta adrenoceptors in the rat amygdala and hippocampus, (-)icyp binding studies were done with membranes from these limbic structures in the presence of 10 microm serotonin to prevent the binding of (-)icyp to serotonin receptors. |
1991-02-12 |
2023-08-11 |
rat |
| P Blier, C de Montign. Electrophysiological investigation of the adaptive response of the 5-HT system to the administration of 5-HT1A receptor agonists. Journal of cardiovascular pharmacology. vol 15 Suppl 7. 1991-02-11. PMID:1702486. |
unitary extracellular recordings were obtained from dorsal raphe 5-ht neurons and dorsal hippocampus pyramidal neurons. |
1991-02-11 |
2023-08-11 |
rat |
| Y Odagaki, T Koyama, S Matsubara, R Matsubara, I Yamashit. Effects of chronic lithium treatment on serotonin binding sites in rat brain. Journal of psychiatric research. vol 24. issue 3. 1991-02-08. PMID:2125080. |
on the other hand, the number of 5-ht1 binding sites labeled with [3h]5-ht was decreased significantly in the hippocampus, but not in the cerebral cortex. |
1991-02-08 |
2023-08-11 |
rat |
| Y Odagaki, T Koyama, S Matsubara, R Matsubara, I Yamashit. Effects of chronic lithium treatment on serotonin binding sites in rat brain. Journal of psychiatric research. vol 24. issue 3. 1991-02-08. PMID:2125080. |
while non-5-ht1a sites, defined as specific [3h]5-ht binding in the presence of 100 nm 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), were not affected by lithium treatment in either brain region, chronic lithium administration reduced significantly the density of 5-ht1a sites labeled with [3h]8-oh-dpat only in the hippocampus, but not in the cerebral cortex. |
1991-02-08 |
2023-08-11 |
rat |
| E Przegaliński, L Jaworska, K Gołembiowsk. The effect of fenfluramine on the thyrotropin-releasing hormone (TRH) content in the rat brain structures and lumbar spinal cord. Neuropeptides. vol 15. issue 4. 1991-01-31. PMID:2124333. |
it was found that fenfluramine had no effect on the trh level in the hypothalamus, hippocampus, occipital cortex, septum, nucleus accumbens and ventral part of the lumbar spinal cord, though the drug produced a profound depletion (by more than 60%) of 5-ht in the hypothalamus, nucleus accumbens, striatum and lumbar spinal cord. |
1991-01-31 |
2023-08-11 |
rat |