| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Sharp, G A Foste. Release of 5-hydroxytryptamine (5-HT) from medullary and mesencephalic raphé neurones after grafting to the rat hippocampus: evidence for regulation by 5-HT1A autoreceptors. Neuroscience letters. vol 132. issue 2. 1992-03-18. PMID:1838408. |
output of 5-ht and its metabolite 5-hydroxyindolacetic acid (5-hiaa) from such grafts was as great (medullary) or greater (mesencephalic) than that measured in the normal intact hippocampus. |
1992-03-18 |
2023-08-11 |
rat |
| T Sharp, G A Foste. Release of 5-hydroxytryptamine (5-HT) from medullary and mesencephalic raphé neurones after grafting to the rat hippocampus: evidence for regulation by 5-HT1A autoreceptors. Neuroscience letters. vol 132. issue 2. 1992-03-18. PMID:1838408. |
systemic administration of the putative 5-ht1a receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) led to a 50-80% reduction in 5-ht levels in hippocampal dialysates from both intact and raphé grafted hippocampus. |
1992-03-18 |
2023-08-11 |
rat |
| F A Dijcks, G S Ruigt, J S de Graa. Antidepressants affect amine modulation of neurotransmission in the rat hippocampal slice--I. Delayed effects. Neuropharmacology. vol 30. issue 11. 1992-03-05. PMID:1663591. |
the effects of long-term treatment with the antidepressant drugs, desipramine (dmi) and mianserin (mia) on neurotransmission in the hippocampal slice were studied by examining the actions of serotonin (5-ht), isoprenaline and (+/-)-baclofen on the population spike in the pyramidal cell layer, recorded in area ca1. |
1992-03-05 |
2023-08-11 |
rat |
| F A Dijcks, G S Ruigt, J S de Graa. Antidepressants affects amine modulation of neurotransmission in the rat hippocampal slice--II. Acute effects. Neuropharmacology. vol 30. issue 11. 1992-03-05. PMID:1663592. |
the effects of this treatment with single doses of dmi and mia on neurotransmission in the hippocampal slice, were studied by examining the actions of serotonin (5-ht), isoprenaline and (+/-)-baclofen on the population spike of the pyramidal cell layer, recorded in area ca1. |
1992-03-05 |
2023-08-11 |
rat |
| J M Klancnik, A Obenaus, A G Phillips, K G Baimbridg. The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat. Neuropharmacology. vol 30. issue 11. 1992-03-05. PMID:1837848. |
the effects of serotonin (5-ht), the 5-ht1a receptor subtype agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) and the 5-ht2 receptor subtype agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) on electrophysiological responses in the dentate gyrus and area ca1 were examined in the in vitro hippocampal slice preparation. |
1992-03-05 |
2023-08-11 |
rat |
| M I Colado, M J Alfaro, F López, V Del Val, M I Martí. The effect of dihydropyridine calcium channel agents on 5-HT metabolism in the CNS of the rat. The Journal of pharmacy and pharmacology. vol 43. issue 9. 1992-03-04. PMID:1723099. |
nisoldipine increased 5-ht turnover in midbrain, hippocampus and cortex, while the effect of nimodipine was restricted to midbrain. |
1992-03-04 |
2023-08-11 |
rat |
| S E File, N Andrew. Low but not high doses of buspirone reduce the anxiogenic effects of diazepam withdrawal. Psychopharmacology. vol 105. issue 4. 1992-02-27. PMID:1771225. |
the findings are consistent with earlier proposals that the increased anxiety during benzodiazepine withdrawal is at least partly caused by an increased release of hippocampal 5-ht. |
1992-02-27 |
2023-08-11 |
rat |
| P S Whitton, L J Fowle. The effect of valproic acid on 5-hydroxytryptamine and 5-hydroxyindoleacetic acid concentration in hippocampal dialysates in vivo. European journal of pharmacology. vol 200. issue 1. 1992-02-25. PMID:1722752. |
the effect of valproic acid on 5-hydroxytryptamine and 5-hydroxyindoleacetic acid concentration in hippocampal dialysates in vivo. |
1992-02-25 |
2023-08-11 |
Not clear |
| P S Whitton, L J Fowle. The effect of valproic acid on 5-hydroxytryptamine and 5-hydroxyindoleacetic acid concentration in hippocampal dialysates in vivo. European journal of pharmacology. vol 200. issue 1. 1992-02-25. PMID:1722752. |
on extracellular 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) has been studied using intracerebral microdialysis of the ventral hippocampus. |
1992-02-25 |
2023-08-11 |
Not clear |
| X M Huang, M P Johnson, D E Nichol. Reduction in brain serotonin markers by alpha-ethyltryptamine (Monase). European journal of pharmacology. vol 200. issue 1. 1992-02-25. PMID:1722753. |
a significant decrease in 5-ht and 5-hiaa levels was also observed in rat hippocampal samples. |
1992-02-25 |
2023-08-11 |
rat |
| M E Newman, B Shapira, B Lere. Regulation of 5-hydroxytryptamine1A receptor function in rat hippocampus by short- and long-term administration of 5-hydroxytryptamine1A agonist and antidepressants. The Journal of pharmacology and experimental therapeutics. vol 260. issue 1. 1992-02-18. PMID:1530973. |
single s.c. injections of the 5-hydroxytryptamine (5-ht)1a receptor agonists buspirone at 4 mg/kg, 8-hydroxy-2-(di-n-propylamino)tetralin at 1 or 4 mg/kg or ipsapirone at 10 mg/kg did not affect 5-ht inhibition of forskolin-stimulated adenylate cyclase activity in rat hippocampal membranes. |
1992-02-18 |
2023-08-11 |
rat |
| W Balduini, S M Candura, L G Cost. Regional development of carbachol-, glutamate-, norepinephrine-, and serotonin-stimulated phosphoinositide metabolism in rat brain. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1684740. |
stimulation of phosphoinositide metabolism by norepinephrine increased with age in hippocampus and cerebral cortex, but decreased in the cerebellum, while the effect of serotonin did not change significantly with age except in cerebellum. |
1992-02-12 |
2023-08-11 |
rat |
| H Hörtnagl, M L Berger, G Sperk, C Pif. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1684835. |
in these six hippocampal subregions the concentrations of noradrenaline, dopamine, serotonin, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid and the putative neurotransmitter amino acids glutamate, aspartate, gaba, glycine and taurine, and the levels of somatostatin and neuropeptide y and the activities of choline acetyltransferase, acetylcholinesterase and glutamate decarboxylase were measured. |
1992-02-07 |
2023-08-11 |
rat |
| H Hörtnagl, M L Berger, G Sperk, C Pif. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1684835. |
the highest molar ratios of total 3-methoxy-4-hydroxyphenylglycol to noradrenaline and 5-hydroxyindoleacetic acid to serotonin were found in the dorsal hippocampus. |
1992-02-07 |
2023-08-11 |
rat |
| P A Broderick, M F Pierce. 5-HT1A agonists uncouple noradrenergic somatodendritic impulse flow and terminal release. Brain research bulletin. vol 27. issue 5. 1992-02-06. PMID:1684526. |
in ca1 region of hippocampus, both buspirone and ipsapirone significantly depressed ne release with potencies greater than those required for the significant depression of 5-ht release. |
1992-02-06 |
2023-08-11 |
Not clear |
| P A Broderic. Adinazolam affects biogenic amine release in hippocampal CA1 neuronal circuitry. Brain research bulletin. vol 27. issue 5. 1992-02-06. PMID:1756387. |
the findings show that the mechanism of action of adinazolam occurs simultaneously on presynaptic release mechanisms for norepinephrine and for serotonin in ca1 region of hippocampus. |
1992-02-06 |
2023-08-11 |
rat |
| J S Kelly, P Larkman, N J Penington, D G Rainnie, H McAllister-Williams, J Hodgkis. Serotonin receptor heterogeneity and the role of potassium channels in neuronal excitability. Advances in experimental medicine and biology. vol 287. 1992-02-06. PMID:1759607. |
data from the hippocampus and drn indicate the 5-ht induced hyperpolarisation to be sensitive to pertussis toxin (ptx) and irreversibly mimicked by gtp gamma s, a non-hydrolysable analogue of gtp, suggesting the involvement of a g protein in k+ channel activation. |
1992-02-06 |
2023-08-11 |
rat |
| J S Kelly, P Larkman, N J Penington, D G Rainnie, H McAllister-Williams, J Hodgkis. Serotonin receptor heterogeneity and the role of potassium channels in neuronal excitability. Advances in experimental medicine and biology. vol 287. 1992-02-06. PMID:1759607. |
the results show that hyperpolarisation evoked by 5-ht in the hippocampus and drn to be mimicked and blocked by 5-ht1a agonists and antagonists. |
1992-02-06 |
2023-08-11 |
rat |
| T Mennini, S Garattin. [Neurobiology of tianeptine. A new pharmaceutic agent]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1721718. |
in ex vivo experiments, tianeptine increased serotonin uptake in the hippocampus and the cortex acutely and after 72 hours following chronic administration for 15 days. |
1992-01-30 |
2023-08-11 |
Not clear |
| B S McEwe. [Stress and hippocampus. An update on current knowledge]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836611. |
because of the positive results obtained with tianeptine on the hypophyseal-adrenal gland function and on the hippocampus, the authors are persuing further investigations to determine whether tianeptine can inhibit the loss of hippocampus nerve cells induced by repeated glucocorticoid administration or repeated stress and whether it potentializes the beneficial effects of glucocorticoids on the noradrenergic, serotonin and gaba benzodiazepin systems. |
1992-01-30 |
2023-08-11 |
rat |