| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinpeng Wang, Baihong Zheng, Dan Zhou, Jie Xing, Honghua Li, Jiayu Li, Zehui Zhang, Beilin Zhang, Ping L. Supplementation of Diet With Different n-3/n-6 PUFA Ratios Ameliorates Autistic Behavior, Reduces Serotonin, and Improves Intestinal Barrier Impairments in a Valproic Acid Rat Model of Autism. Frontiers in psychiatry. vol 11. 2020-10-10. PMID:33033482. |
in conclusion, dietary supplementation of n-3/n-6 pufas (1:5) significantly improves vpa-induced autism-like behaviors in rats, which may be, at least partially, related to the increased hippocampal 5-ht. |
2020-10-10 |
2023-08-13 |
rat |
| Toyoshi Umezu, Taizo Kita, Masatoshi Morit. Hyperactive behavioral phenotypes and an altered brain monoaminergic state in male offspring mice with perinatal hypothyroidism. Toxicology reports. vol 6. 2020-10-01. PMID:31673505. |
significant decreases in dopamine (da) and serotonin turnover were observed in the striatum (st), nucleus accumbens, hypothalamus, and hippocampus in male mice with perinatal hypothyroidism. |
2020-10-01 |
2023-08-13 |
mouse |
| Hirotsugu Azechi, Kōsuke Hakamada, Takanobu Yamamot. A new inbred strain of Fawn-Hooded rats demonstrates mania-like behavioural and monoaminergic abnormalities. IBRO reports. vol 7. 2020-10-01. PMID:31763490. |
serotonin and noradrenaline levels were low in the prefrontal cortex and the hippocampus of fh/hamslc rats, but high serotonin turnover was observed in the prefrontal cortex, hippocampus, and striatum. |
2020-10-01 |
2023-08-13 |
rat |
| Toyoshi Umezu, Taizo Kita, Masatoshi Morit. Dataset on effects of perinatal exposure to propylthiouracil on serum T4, body weight gain, day of eye opening and brain monoamine contents in offspring mice. Data in brief. vol 28. 2020-10-01. PMID:31872013. |
this dataset also describes content of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva), 3-methoxytyramine (3-mt), 5-ht, and 5-hydroxyindoleacetic acid (5-hiaa) and their turnover in the hypothalamus, hippocampus, and nucleus accumbens of male offspring mice perinatally exposed to ptu. |
2020-10-01 |
2023-08-13 |
mouse |
| Jenessa N Johnston, Jonathan S Thacker, Charissa Desjardins, Brian D Kulyk, Raquel Romay-Tallon, Lisa E Kalynchuk, Hector J Carunch. Ketamine Rescues Hippocampal Reelin Expression and Synaptic Markers in the Repeated-Corticosterone Chronic Stress Paradigm. Frontiers in pharmacology. vol 11. 2020-10-01. PMID:32982757. |
we also assessed the effects of reelin and ketamine on hippocampal and cerebellar synpatosomes, and on serotonin transporter clustering in peripheral lymphocytes to determine reelin and ketamine's impact at the synaptic and peripheral levels. |
2020-10-01 |
2023-08-13 |
rat |
| Sophia Frango. Bulking up the hippocampus in schizophrenia: a role for 5-HT BJPsych open. vol 2. issue 4. 2020-10-01. PMID:27703789. |
bulking up the hippocampus in schizophrenia: a role for 5-ht the volume of the hippocampus is reduced in patients with schizophrenia, and this deficit tends to become more pronounced with chronicity. |
2020-10-01 |
2023-08-13 |
Not clear |
| Gregers Wegener, Vallo Volk. Nitric Oxide Synthase Inhibitors as Antidepressants. Pharmaceuticals (Basel, Switzerland). vol 3. issue 1. 2020-10-01. PMID:27713253. |
moreover, several of the conventional neurotransmitters, including serotonin, glutamate and gaba, are intimately regulated by no, and distinct classes of antidepressants have been found to modulate the hippocampal no level in vivo. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. |
divergent roles of central serotonin in adult hippocampal neurogenesis. |
2020-10-01 |
2023-08-13 |
mouse |
| Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. |
therefore, tremendous effort has been made to decipher how central 5-ht regulates adult hippocampal neurogenesis. |
2020-10-01 |
2023-08-13 |
mouse |
| Ning-Ning Song, Ying Huang, Xin Yu, Bing Lang, Yu-Qiang Ding, Lei Zhan. Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28713247. |
these recent findings provide unique insights to interpret the multifaceted roles of central 5-ht on adult hippocampal neurogenesis and its associated effects on depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Yang Yang, Zhiying Hu, Xiaoxue Du, Henry Davies, Xue Huo, Marong Fan. miR-16 and Fluoxetine Both Reverse Autophagic and Apoptotic Change in Chronic Unpredictable Mild Stress Model Rats. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28790887. |
it has been suggested that mir-16 regulates serotonin transporters (sert) via raphe nuclei and hippocampal responses to antidepressants. |
2020-10-01 |
2023-08-13 |
rat |
| Marenka Smit, David Vállez García, Bauke M de Jong, Evelien Zoons, Jan Booij, Rudi A Dierckx, Antoon T Willemsen, Erik F de Vries, Anna L Bartels, Marina A Tijsse. Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [ Frontiers in neurology. vol 9. 2020-10-01. PMID:29541052. |
relationships between serotonin transporter binding in the raphe nuclei, basal ganglia, and hippocampus with clinical symptoms in cervical dystonia: a [ alterations of the central serotonergic system have been implicated in the pathophysiology of dystonia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dong-Hai Zhao, Yan-Chun Wang, Lian-Wen Zheng, Bing-Yu Liu, Li-Ping Gua. Antidepressant-like Effect of a Chalcone Compound, DHIPC and Its Possible Mechanism. Iranian journal of pharmaceutical research : IJPR. vol 17. issue 1. 2020-10-01. PMID:29755551. |
it was found that dhipc significantly increased the concentrations of the main neurotransmitters serotonin and noradrenalin, and also significantly increased 5-hydroxyindoleacetic acid contents in hippocampus, hypothalamus, and cortex in brain part. |
2020-10-01 |
2023-08-13 |
mouse |
| S Creagh, D Warden, M A Latif, A Payda. The New Classes of Synthetic Illicit Drugs Can Significantly Harm the Brain: A Neuro Imaging Perspective with Full Review of MRI Findings. Clinical radiology & imaging journal. vol 2. issue 1. 2020-10-01. PMID:30027157. |
these drugs have detrimental (and often irreversible) effects on the brain and primarily affect the central nervous system by two mechanisms: 1) neural hyper stimulation via increasing activation of certain neurotransmitters (norepinephrine, dopamine, and serotonin), 2) cause significant reduction in cns neural connectivity affecting various brain regions such as the basal ganglia, hippocampus, cerebellum, parietal lobe, and globus pallidus. |
2020-10-01 |
2023-08-13 |
human |
| Carina Soares-Cunha, Bárbara Coimbra, Sónia Borges, Ana Verónica Domingues, Deolinda Silva, Nuno Sousa, Ana João Rodrigue. Mild Prenatal Stress Causes Emotional and Brain Structural Modifications in Rats of Both Sexes. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30034328. |
interestingly, these results were accompanied by structural modifications of the bed nucleus of stria terminalis (bnst) and hippocampus, as well as decreased norepinephrine and dopamine levels in the bnst, and serotonin levels in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Arina Rawat, Jackey Guo, Thibault Renoir, Terence Y Pang, Anthony J Hanna. Hypersensitivity to sertraline in the absence of hippocampal 5-HT Environmental epigenetics. vol 4. issue 2. 2020-10-01. PMID:30046455. |
hypersensitivity to sertraline in the absence of hippocampal 5-ht the male germ line is capable of transmitting a legacy of stress exposure to the next generation of offspring. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Oleuropein reduces anxiety-like responses by activating of serotonergic and neuropeptide Y (NPY)-ergic systems in a rat model of post-traumatic stress disorder. Animal cells and systems. vol 22. issue 2. 2020-10-01. PMID:30460087. |
ole also blocked the sps-induced decrease in hippocampal serotonin and neuropeptide y expression in hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Jian Liu, Yu-Hong Wang, Wei Li, Lin Liu, Hui Yang, Pan Meng, Yuan-Shan Ha. Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression. Neural regeneration research. vol 14. issue 2. 2020-10-01. PMID:30531012. |
levels of basic fibroblast growth factor, angiogenic factor 1, glial cell line-derived neurotrophic factor, transforming growth factor β1, leukemia inhibitory factor and 5-hydroxytryptamine in the hippocampal neurovascular unit co-culture system were measured by enzyme-linked immunosorbent assay. |
2020-10-01 |
2023-08-13 |
rat |
| Arnauld Belmer, Kate Beecher, Angela Jacques, Omkar L Patkar, Florian Sicherre, Selena E Bartlet. Axonal Non-segregation of the Vesicular Glutamate Transporter VGLUT3 Within Serotonergic Projections in the Mouse Forebrain. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31133811. |
therefore, we combined immunohistochemistry, high resolution confocal imaging, and 3d-reconstruction techniques to map and quantify the distribution of vglut3 immunoreactive boutons within 5-ht vs. sert-positive axons in various regions of the mouse forebrain, including the prefrontal cortex, nucleus accumbens core and shell, bed nucleus of the stria terminalis, dorsal striatum, lateral septum, basolateral and central amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Iva Lukić, Dmitriy Getselter, Omry Koren, Evan Elliot. Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31231198. |
in addition, in mice that were not subjected to atd, gf mice displayed higher levels of tryptophan, serotonin and 5-hydroxyindoleacetic acid (the main degradation product of serotonin) in medial prefrontal cortex (mpfc) and hippocampus (hippo), compared to spf mice. |
2020-10-01 |
2023-08-13 |
mouse |