| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
the serotonin levels in the colon, hippocampus, and serum of mice, as well as the human colon carcinoma cells (caco-2), were measured by elisa assays. |
2021-05-10 |
2023-08-13 |
mouse |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
a. muciniphila and its evs may have a biological effect on the induction of serotonin levels in the colon and hippocampus of mice. |
2021-05-10 |
2023-08-13 |
mouse |
| Rezvan Yaghoubfar, Ava Behrouzi, Fatemeh Ashrafian, Arefeh Shahryari, Hamid Reza Moradi, Samira Choopani, Shima Hadifar, Farzam Vaziri, Seyed Ali Nojoumi, Abolfazl Fateh, Shohreh Khatami, Seyed Davar Siada. Modulation of serotonin signaling/metabolism by Akkermansia muciniphila and its extracellular vesicles through the gut-brain axis in mice. Scientific reports. vol 10. issue 1. 2021-05-10. PMID:33335202. |
both the bacterium and its evs had significant effects on the mrna expression of genes, involved in serotonin signaling/metabolism in the colon and hippocampus of mice. |
2021-05-10 |
2023-08-13 |
mouse |
| Hang Xu, Xiang Yang Zhang, Wei Wen Wang, Jiesi Wan. Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain. Frontiers in pharmacology. vol 12. 2021-05-08. PMID:33953673. |
furthermore, hcq decreased the mrna expression of interleukin-1beta, corticotropin-releasing hormone (crh), a serotonin transporter (slc6a4), and a microglia maker (aif1) in the hippocampus and decreased the mrna expression of brain-derived neurotrophic factor (bdnf) in both the hippocampus and amygdala. |
2021-05-08 |
2023-08-13 |
mouse |
| Linlin Zhang, Yongzhao Fan, Xiaoyang Kong, Wu Ha. Neuroprotective effect of different physical exercises on cognition and behavior function by dopamine and 5-HT level in rats of vascular dementia. Behavioural brain research. vol 388. 2021-05-04. PMID:32339549. |
the level in hippocampal dopamine and 5-ht were detected by microdialysis coupled with high performance liquid chromatography. |
2021-05-04 |
2023-08-13 |
rat |
| Linlin Zhang, Yongzhao Fan, Xiaoyang Kong, Wu Ha. Neuroprotective effect of different physical exercises on cognition and behavior function by dopamine and 5-HT level in rats of vascular dementia. Behavioural brain research. vol 388. 2021-05-04. PMID:32339549. |
in addition, hippocampal dopamine and 5-ht level significantly decreased in vd group when compared with c group (p < 0.001); hippocampal dopamine and 5-ht level in ve-vd, ie-vd and te-vd groups were significantly increased when compared with vd group (p < 0.05). |
2021-05-04 |
2023-08-13 |
rat |
| Madhusmita P Sahu, Yago Pazos-Boubeta, Anna Steinzeig, Katja Kaurinkoski, Michela Palmisano, Olgierd Borowecki, Timo Petteri Piepponen, Eero Castré. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Frontiers in molecular neuroscience. vol 14. 2021-05-04. PMID:33935645. |
consistent with increased 5-ht, the proliferation of hippocampal progenitors is significantly increased, however, long-term survival of newborn cells is unchanged. |
2021-05-04 |
2023-08-13 |
mouse |
| Marta Portero-Tresserra, D Rojic-Becker, C Vega-Carbajal, G Guillazo-Blanch, A Vale-Martínez, M Martí-Nicoloviu. Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33168891. |
noradrenaline (na), dopamine (da), serotonin (5-ht) and its metabolites were measured by high-performance liquid chromatography with electrochemical detection (hplc-ed) in nine brain regions: cerebellum, pons, midbrain, hypothalamus, thalamus, hippocampus, striatum, frontal cortex, and occipital cortex. |
2021-05-03 |
2023-08-13 |
rat |
| Marta Portero-Tresserra, D Rojic-Becker, C Vega-Carbajal, G Guillazo-Blanch, A Vale-Martínez, M Martí-Nicoloviu. Caloric restriction modulates the monoaminergic system and metabolic hormones in aged rats. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:33168891. |
cr was seen to increase the na levels that are altered by aging in specific brain regions like the striatum, thalamus, cerebellum and hypothalamus, and the da levels in the striatum, as well as modifying the 5-ht levels in the striatum, hypothalamus, pons and hippocampus. |
2021-05-03 |
2023-08-13 |
rat |
| Maria Grazia Morgese, Stefania Schiavone, Maria Bove, Anna Laura Colia, Stefania Dimonte, Paolo Tucci, Luigia Trabac. N-3 PUFA Prevent Oxidative Stress in a Rat Model of Beta-Amyloid-Induced Toxicity. Pharmaceuticals (Basel, Switzerland). vol 14. issue 4. 2021-05-02. PMID:33917814. |
results showed increased hippocampal ros and nox2 levels, serotonin turnover, kynurenine, and noradrenaline contents in aβ-treated rats. |
2021-05-02 |
2023-08-13 |
rat |
| Melkamu Alemu Abame, Yang He, Song Wu, Zhifei Xie, Jian Zhang, Xudong Gong, Chunhui Wu, Jingshan She. Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. Neuroscience letters. vol 744. 2021-04-30. PMID:33388355. |
chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. |
2021-04-30 |
2023-08-13 |
mouse |
| Melkamu Alemu Abame, Yang He, Song Wu, Zhifei Xie, Jian Zhang, Xudong Gong, Chunhui Wu, Jingshan She. Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. Neuroscience letters. vol 744. 2021-04-30. PMID:33388355. |
chronic cbd 100 mg/kg administration resulted in significant increases in serotonin (5-ht) and noradrenaline (na) levels in the hippocampus (hpc). |
2021-04-30 |
2023-08-13 |
mouse |
| Sheng Wei, Xiwen Geng, Zifa Li, Kaiyong Xu, Minghui Hu, Hongyun Wu, Wei Shi, Mingqi Qia. A forced swim-based rat model of premenstrual depression: effects of hormonal changes and drug intervention. Aging. vol 12. issue 23. 2021-04-27. PMID:33229622. |
further, the model rats showed significant changes in the serum levels of estrogen and progesterone, hippocampal levels of allopregnanolone, 5-hydroxytryptamine, norepinephrine, and γ-aminobutyric acid (gaba), and in the expression of gaba |
2021-04-27 |
2023-08-13 |
rat |
| Ji-Duo Shen, Yue-Wen Zhang, Bao-Ying Wang, Li Bai, Shuai-Fei Lu, Lei-Lei Zhu, Ming Bai, Yu-Cheng Li, Er-Ping X. Effects of resveratrol on the levels of ATP, 5-HT and GAP-43 in the hippocampus of mice exposed to chronic unpredictable mild stress. Neuroscience letters. vol 735. 2021-04-23. PMID:32621948. |
effects of resveratrol on the levels of atp, 5-ht and gap-43 in the hippocampus of mice exposed to chronic unpredictable mild stress. |
2021-04-23 |
2023-08-13 |
mouse |
| Claudia Fuchs, Laura Gennaccaro, Elisa Ren, Giuseppe Galvani, Stefania Trazzi, Giorgio Medici, Manuela Loi, Erin Conway, Orrin Devinsky, Roberto Rimondini, Elisabetta Cian. Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder. Neuropharmacology. vol 167. 2021-04-23. PMID:31469994. |
here we show a dysregulation of hippocampal and cortical serotonergic (5-ht) receptor expression in heterozygous cdkl5 knockout (ko) female mice, suggesting that impaired 5-ht neurotransmission contributes to cdd. |
2021-04-23 |
2023-08-13 |
mouse |
| Marta Barenys, Ingrid Reverte, Stefan Masjosthusmann, Jesús Gómez-Catalán, Ellen Fritsch. Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway. Neurotoxicology. vol 78. 2021-04-21. PMID:31812710. |
in rat, postnatal exposure towards mdma also caused locomotor deficits as well as impaired spatial learning that might be associated with decreased serotonin levels in the hippocampus. |
2021-04-21 |
2023-08-13 |
mouse |
| Sadia Basharat Ali, Khalid Mahmood, Raheel Saeed, Tabinda Salman, Muhammad Iqbal Choudhary, Darakhshan Jabeen Halee. Elevated anxiety, hypoactivity, memory deficits, decreases of brain serotonin and 5-HT-1A receptors expression in rats treated with omeprazole. Toxicological research. vol 37. issue 2. 2021-04-21. PMID:33868980. |
associated changes in brain serotonin (5-hydroxytryptamine; 5-ht) and dopamine metabolism and the expression of 5-ht-1a receptors in the raphe and hippocampus were also determined. |
2021-04-21 |
2023-08-13 |
rat |
| Silvia Vincentiis, Juliana A Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Francisco Arruda, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo F Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 117. 2021-04-20. PMID:33639436. |
genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. |
2021-04-20 |
2023-08-13 |
Not clear |
| Hidekazu Tanaka, Toshinori Sawano, Naoko Konishi, Risako Harada, Chiaki Takeuchi, Yuki Shin, Hiroko Sugiura, Jin Nakatani, Takahiro Fujimoto, Kanato Yamagat. Serotonin induces Arcadlin in hippocampal neurons. Neuroscience letters. vol 721. 2021-04-19. PMID:31981722. |
serotonin induces arcadlin in hippocampal neurons. |
2021-04-19 |
2023-08-13 |
human |
| Swati Sahoo, Prashant S Kharkar, Niteshkumar U Sahu, Brijesh . Anxiolytic activity of Psidium guajava in mice subjected to chronic restraint stress and effect on neurotransmitters in brain. Phytotherapy research : PTR. vol 35. issue 3. 2021-04-19. PMID:33034100. |
neurotransmitters such as monoamines (serotonin, norepinephrine, and dopamine), γ-aminobutyric acid (gaba), and glutamate were estimated in different regions of the brain (cortex, hippocampus, and cerebellum and brain stem). |
2021-04-19 |
2023-08-13 |
mouse |