| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heba M Fahmy, Yasser A Khadrawy, Taiseer M Abd-El Daim, Amena S Elfeky, Amera A Abd Rabo, Amira B Mustafa, Islam T Mostaf. Thymoquinone-encapsulated chitosan nanoparticles coated with polysorbate 80 as a novel treatment agent in a reserpine-induced depression animal model. Physiology & behavior. vol 222. 2021-06-21. PMID:32353367. |
in addition, a significant decrease in the monoamine neurotransmitters serotonin (5-ht), norepinephrine (ne) and dopamine (da) was recorded in the cortex, hippocampus and striatum of reserpine-treated rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
d-lys-3-ghrp-6 impairs memory consolidation and downregulates the hippocampal serotonin ht1a, ht7 receptors and glutamate glua1 subunit of ampa receptors. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
we aimed to evaluate the effect of intracerebral injection of a ghrelin receptor antagonist (d-lys-3-ghrp-6) on memory consolidation in the inhibitory avoidance task and on the gene expression levels of serotonin ht1a and ht7 receptors, glutamate glun1 subunit of the nmda and glua1 subunit of the ampa receptors and calcium/calmodulin kinase ii-α in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
meanwhile, it led to a significant downregulation of the mrna expression levels of the hippocampal serotonin ht1a and ht7 receptors and glutamate glua1 subunit of the ampa receptors, but could not affect that of glun1 subunit of the nmda receptors and camkii-α. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
it seems that part of the impairing effect of d-lys-3-ghrp-6 on inhibitory avoidance memory consolidation might be due to a decrease in the expression of serotonin ht1a and ht7 receptors and glutamate ampa receptors in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Peng Wang, Xiaoxia Gao, Fang Zhao, Yao Gao, Kexin Wang, Jun-Sheng Tian, Zhenyu Li, Xue-Mei Qi. Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis. ACS chemical neuroscience. vol 12. issue 12. 2021-06-21. PMID:34060807. |
compared with the control group, the levels of neurotransmitters including 5-hydroxytryptamine (5-ht), acetylcholine, glutamate (glu), and dopamine (da) in the hippocampus and 5-ht, norepinephrine, γ-aminobutyric acid (gaba), and 5-hydroxyindoleacetic acid in serum were significantly changed in the cums rats. |
2021-06-21 |
2023-08-13 |
rat |
| Yong Li, Qian Jiao, Xixun Du, Hong Jian. Sirt1/FoxO1-Associated MAO-A Upregulation Promotes Depressive-Like Behavior in Transgenic Mice Expressing Human A53T α-Synuclein. ACS chemical neuroscience. vol 11. issue 22. 2021-06-18. PMID:33155799. |
we detected reduced levels of na and 5-ht in the hippocampus and na in the locus coeruleus of 6-month a53t mice. |
2021-06-18 |
2023-08-13 |
mouse |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
evaluation of the hippocampal immunoreactivity of the serotonin 5-ht1a, 5-ht2 and 5-ht7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
therefore, to gather more details about the state of the serotoninergic system in the hippocampus under an epileptogenic process, we studied the immunoreactivity of three 5-ht receptors (5-ht1a, 5-ht2 and 5-ht7) as well as the extracellular levels of 5-ht in the hippocampal tissue of epileptic rats with fr. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
a general depletion of the 5-ht and 5-hiia levels in hippocampal tissue from epileptic animals compared with those in controls was observed; in addition, a general decrease in immunoreactivity for the three receptors was found, especially in the dg, which may support the establishment of an excitatory/inhibitory imbalance in the trisynaptic circuit that underlies the fr generation process. |
2021-06-18 |
2023-08-13 |
rat |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
deep brain stimulation of the dorsal raphe abolishes serotonin 1a facilitation of ampa receptor-mediated synaptic currents in the ventral hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
for that, we tested the influence of dbs upon the neuromodulatory action of serotonin on excitatory post-synaptic currents (epscs) in the ventral hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Xianan Sun, Yi Zu, Xiang Li, Shulei Zhao, Xiao Sun, Lu Li, Xinjing Zhang, Wei Wang, Yuezhu Liang, Wenyao Wang, Xuankai Liang, Mingqi Gao, Chi Sun, Xue Guan, Man Tan. Corticosterone-induced Hippocampal 5-HT Responses were Muted in Depressive-like State. ACS chemical neuroscience. vol 12. issue 5. 2021-06-18. PMID:33586968. |
corticosterone-induced hippocampal 5-ht responses were muted in depressive-like state. |
2021-06-18 |
2023-08-13 |
mouse |
| Carey Wilson, Jake Rogers, Feng Chen, Shanshan Li, Paul A Adlard, Anthony J Hannan, Thibault Renoi. Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34052925. |
exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. |
2021-06-15 |
2023-08-13 |
mouse |
| Carey Wilson, Jake Rogers, Feng Chen, Shanshan Li, Paul A Adlard, Anthony J Hannan, Thibault Renoi. Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34052925. |
here, we investigate hippocampal adult-born cell survival and synaptic plasticity (long-term potentiation, ltp, and long-term depression, ltd) in serotonin transporter (5-htt) knockout (ko) mice. |
2021-06-15 |
2023-08-13 |
mouse |
| Danielle M Diniz, Francesca Calabrese, Paola Brivio, Marco A Riva, Joanes Grandjean, Judith R Homber. BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats. International journal of molecular sciences. vol 22. issue 9. 2021-06-15. PMID:34068707. |
bdnf overexpression in the ventral hippocampus promotes antidepressant- and anxiolytic-like activity in serotonin transporter knockout rats. |
2021-06-15 |
2023-08-13 |
human |
| Andrei Turkin, Oksana Tuchina, Friederike Klempi. Microglia Function on Precursor Cells in the Adult Hippocampus and Their Responsiveness to Serotonin Signaling. Frontiers in cell and developmental biology. vol 9. 2021-06-12. PMID:34109176. |
microglia function on precursor cells in the adult hippocampus and their responsiveness to serotonin signaling. |
2021-06-12 |
2023-08-13 |
Not clear |
| Xi Li, Qingqing Liu, Jiaoyan Yu, Ruitao Zhang, Ting Sun, Wei Jiang, Na Hu, Peng Yang, Li Luo, Jing Ren, Qinhui Wang, Yan Wang, Qi Yan. Costunolide ameliorates intestinal dysfunction and depressive behaviour in mice with stress-induced irritable bowel syndrome Food & function. vol 12. issue 9. 2021-06-07. PMID:33977961. |
mice were subjected to chronic unpredictable mild stress to trigger ibs, and some were administered cos. behavioural tests, histochemical assays, western blotting, and measurement of 5-hydroxytryptamine (5-ht) levels in the colon and hippocampus were applied to monitor the physiological and molecular consequences of cos treatment in ibs mice. |
2021-06-07 |
2023-08-13 |
mouse |
| Xi Li, Qingqing Liu, Jiaoyan Yu, Ruitao Zhang, Ting Sun, Wei Jiang, Na Hu, Peng Yang, Li Luo, Jing Ren, Qinhui Wang, Yan Wang, Qi Yan. Costunolide ameliorates intestinal dysfunction and depressive behaviour in mice with stress-induced irritable bowel syndrome Food & function. vol 12. issue 9. 2021-06-07. PMID:33977961. |
cos was also found to upregulate glun2a, bdnf, p-erk1/2, and p-creb expression and 5-ht levels in hippocampal cells but inhibited 5-ht metabolism. |
2021-06-07 |
2023-08-13 |
mouse |
| Katharina Schönhoff, Eva-Lotta von Rüden, Ines Koska, Isabel Seiffert, Heidrun Potschk. Hippocampal and Septal 5-HT Neuroscience. vol 465. 2021-06-04. PMID:33836244. |
hippocampal and septal 5-ht experimental and clinical data suggest an impact of serotonergic signaling on seizure susceptibility and epilepsy-associated psychiatric comorbidities. |
2021-06-04 |
2023-08-13 |
Not clear |