| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuiyu Lu, Jeih-San Liow, Sami S Zoghbi, Jinsoo Hong, Robert B Innis, Victor W Pik. Evaluation of [C]S14506 and [F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors. Current radiopharmaceuticals. vol 3. issue 1. 2021-10-20. PMID:20657759. |
the ratios of radioactivity in 5-ht(1a) receptor-rich regions, such as cingulate or hippocampus to that in receptor-poor cerebellum reached between 1.35 and 1.5 at 60 min for both [(11)c]s14506 and [(18)f]s14506. |
2021-10-20 |
2023-08-12 |
rat |
| Xiaoyu Pan, Ling Chen, Wen Xu, Shihui Bao, Jun Wang, Xiao Cui, Shichao Gao, Kaiping Liu, Shivani Avasthi, Meixi Zhang, Ruijie Che. Activation of monoaminergic system contributes to the antidepressant- and anxiolytic-like effects of J147. Behavioural brain research. vol 411. 2021-10-18. PMID:34023306. |
in neurochemical assays, studies suggested that serotonin and noradrenaline levels were significantly increased in the frontal cortex and hippocampus after treatment of j147 by the high-performance liquid chromatography (hplc) with an electrochemical detector. |
2021-10-18 |
2023-08-13 |
mouse |
| Yanpo Si, Xiaohui Chen, Tao Guo, Wenjun Wei, Lili Wang, Fei Zhang, Xiaoya Sun, Mengqi Li. Comprehensive 16S rDNA Sequencing and LC-MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine-Induced Insomnia Rats Treated with Lilium brownie. Neurochemical research. 2021-10-18. PMID:34661797. |
it was also found that the most of metabolic phenotypes in serum, hypothalamus and hippocampus perturbed by pcpa were regulated towards normal after lb intervention, especially 5-hydroxy-l-tryptophan of the hypothalamus involving in 5-ht metabolism. |
2021-10-18 |
2023-08-13 |
rat |
| Xiwen Geng, Hongyun Wu, Zifa Li, Chuanfen Li, Dan Chen, Jiancheng Zong, Zimin Liu, Sheng Wei, Wei Pen. Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway. Oxidative medicine and cellular longevity. vol 2021. 2021-10-15. PMID:34646421. |
in the hippocampus and prefrontal cortex, concentrations of 5-ht and its metabolite 5-hydroxyindoleacetic acid, as well as monoamine oxidase a, glucocorticoid receptor, and 5-ht1a receptor expression levels, were measured. |
2021-10-15 |
2023-08-13 |
rat |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
following nor and epm testing hippocampal norepinephrine (ne), 5, hydroxytryptamine (5-ht), 5, hydroxyindole acetic acid (5-hiaa), corticosterone (cort) and interleukin-6 (il-6) were determined and serum collected for basal cort analysis. |
2021-10-13 |
2023-08-13 |
mouse |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
si impaired performance in the nor and the fst, reduced hippocampal 5-ht, increased hippocampal il-6 and increased serum cort post-fst in young mice. |
2021-10-13 |
2023-08-13 |
mouse |
| Annabelle Panossian, Michael W Cave, Bhavik A Patel, Emily L Brooks, Melanie S Flint, Mark S Yeoma. Effects of age and social isolation on murine hippocampal biochemistry and behavior. Mechanisms of ageing and development. vol 191. 2021-10-13. PMID:32866520. |
aged mice either failed to respond significantly to si (nor, fst, hippocampal 5-ht, serum cort post fst) or si had synergistic effects with age (hippocampal ne, 5-hiaa:5-ht). |
2021-10-13 |
2023-08-13 |
mouse |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
chronic escitalopram treatment does not alter the effects of neonatal stress on hippocampal bdnf levels, 5-ht early life stress is considered a risk factor for the development of long-term psychiatric disorders. |
2021-10-13 |
2023-08-13 |
Not clear |
| Lorena Henn, Natália C Zanta, Carlos Eduardo N Girardi, Deborah Sucheck. Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33063280. |
the goal of the present study was to examine the effects of a chronic treatment with escitalopram (esc) on the hippocampal levels of bdnf and neuropeptide y (npy), expression of serotonin type 1a receptor (5-ht |
2021-10-13 |
2023-08-13 |
Not clear |
| Wenting Fang, Naian Xiao, Guirong Zeng, Daode Bi, Xiaoman Dai, Xue Mi, Qinyong Ye, Xiaochun Chen, Jing Zhan. APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34611141. |
furthermore, apoe4 increased stress-induced depression-like behaviors, accompanied by declines in the hippocampal 5-ht (1a) radioligand [18f] mppf uptake evidenced by positron emission tomography (pet). |
2021-10-11 |
2023-08-13 |
mouse |
| Ekram Nemr Abd Al Haleem, Hebatalla I Ahmed, Reem N El-Nag. Lycopene and Chrysin through Mitigation of Neuroinflammation and Oxidative Stress Exerted Antidepressant Effects in Clonidine-Induced Depression-like Behavior in Rats. Journal of dietary supplements. 2021-10-11. PMID:34633271. |
lycopene and chrysin were used to correct the concentrations of noradrenaline and serotonin hippocampal tissue concentrations. |
2021-10-11 |
2023-08-13 |
rat |
| Kai-Jie He, Yu-Ting Zhang, Shi-Zhuang Wei, Shu-Min Jiang, Lin Xu, Chao Ren, Fen Wan. Impact of Maternal Separation on Dopamine System and its Association with Parkinson's Disease. Neuromolecular medicine. vol 22. issue 3. 2021-10-07. PMID:31933131. |
an increasing number of studies has found that ms not only affects the function of the hypothalamic-pituitary-adrenal axis and hippocampal 5-hydroxytryptamine system, but also causes dysfunction of the central dopamine (da) system and increases the susceptibility of dopaminergic neurons to pathogenic factors of parkinson's disease (pd), for instance, 6-hydroxydopamine, thus impairing motor function. |
2021-10-07 |
2023-08-13 |
Not clear |
| Parul, Akanksha Mishra, Sonu Singh, Seema Singh, Virendra Tiwari, Swati Chaturvedi, Muhammad Wahajuddin, Gautam Palit, Shubha Shukl. Chronic unpredictable stress negatively regulates hippocampal neurogenesis and promote anxious depression-like behavior via upregulating apoptosis and inflammatory signals in adult rats. Brain research bulletin. vol 172. 2021-10-07. PMID:33895271. |
cus exposure in rats reduce dopamine and serotonin level in cortex and hippocampus, which result in increased anxiety and depression-like phenotypes. |
2021-10-07 |
2023-08-13 |
rat |
| Sonali N Reisinger, Eryan Kong, Deeba Khan, Stefan Schulz, Marianne Ronovsky, Stefanie Berger, Orsolya Horvath, Maureen Cabatic, Angelika Berger, Daniela D Polla. Maternal immune activation epigenetically regulates hippocampal serotonin transporter levels. Neurobiology of stress. vol 4. 2021-10-06. PMID:27981188. |
maternal immune activation epigenetically regulates hippocampal serotonin transporter levels. |
2021-10-06 |
2023-08-13 |
mouse |
| Francesco De Luc. Endocrinological Abnormalities in Autism. Seminars in pediatric neurology. vol 35. 2021-10-05. PMID:32892953. |
a number of chemical messengers, such as various hormones and hormone-like substances, along with neurotransmitters, such as serotonin, dopamine, and norepinephrine, are directly or indirectly linked with the encoding of social behavior via their action at the amygdala, hippocampus, and other related brain structures known to be involved in different aspects of social development. |
2021-10-05 |
2023-08-13 |
Not clear |
| Carolina Aparecida Faria Almeida, Antonio Alves Pereira-Junior, Jéssica Gonçalves Rangel, Bruna Pinheiro Pereira, Karla Cristinne Mancini Costa, Vitor Bruno, Gabriela Oliveira Silveira, Carla Speroni Ceron, Mauricio Yonamine, Rosana Camarini, Raphael Caio Tamborelli Garcia, Tania Marcourakis, Larissa Helena Torre. Ayahuasca, a psychedelic beverage, modulates neuroplasticity induced by ethanol in mice. Behavioural brain research. vol 416. 2021-10-05. PMID:34437939. |
dopamine receptors, serotonin receptors, dynorphin, and prodynorphin levels were quantified in the striatum and hippocampus by blot analysis. |
2021-10-05 |
2023-08-13 |
mouse |
| Ning Jiang, Lv Jingwei, Haixia Wang, Hong Huang, Qiong Wang, Guirong Zeng, Shanshan Li, Xinmin Li. Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats. Behavioural brain research. vol 393. 2021-10-04. PMID:32464121. |
in addition, ppd decreased the elevated levels of cort and proinflammatory cytokines (il-6, il-1β and tnf-α) in the serum and neurotransmitters (5-ht and ne) in the hippocampus and pfc induced by cums. |
2021-10-04 |
2023-08-13 |
rat |
| Xian Ding, Xiang Gao, Zhichun Wang, Xuliang Jiang, Shunmei Lu, Jingjing Xu, Guowei Qin, Zhengfeng Gu, Dongxiao Huan. Preoperative Chronic and Acute Pain Affects Postoperative Cognitive Function Mediated by Neurotransmitters. Journal of molecular neuroscience : MN. vol 71. issue 3. 2021-10-04. PMID:32901371. |
like anxiety, cci increased 5-hydroxytryptamine (5-ht) levels in the prefrontal cortex and hippocampus. |
2021-10-04 |
2023-08-13 |
mouse |
| Felipe de Jesus Jiménez Vásquez, Diana Méndez Guerrero, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350985. |
decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test. |
2021-09-30 |
2023-08-13 |
rat |
| Felipe de Jesus Jiménez Vásquez, Diana Méndez Guerrero, Moisés Rubio Osornio, María Del Carmen Rubio Osornio, Sandra Orozco Suárez, Socorro Retana-Márque. Decreased serotonin content and release in the ventral hippocampus of prenatally stressed male rats in response to forced swim test. Acta neurobiologiae experimentalis. vol 80. issue 4. 2021-09-30. PMID:33350985. |
prenatal stress modifies the serotonergic system by altering the synthesis, metabolism, receptors and serotonin content in the hippocampus. |
2021-09-30 |
2023-08-13 |
rat |