| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
methiothepin (10 mg kg(-1) s.c.) further enhanced the 5-ht rise induced by fluoxetine+way 100635, to 835+/-179% in frontal cortex and 456+/-24% in dorsal hippocampus. |
2000-06-27 |
2023-08-12 |
rat |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
further enhanced the 5-ht increase produced by fluoxetine+way 100635 more in frontal cortex (613+/-134%) than in dorsal hippocampus (353+/-59%). |
2000-06-27 |
2023-08-12 |
rat |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
locally applied, fluoxetine (10 - 300 microm; ec(50)=28 - 29 microm) and citalopram (1 - 30 microm; ec(50)=1.0 - 1.4 microm) increased the 5-ht output two to three times more in frontal cortex than in dorsal hippocampus. |
2000-06-27 |
2023-08-12 |
rat |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
these data suggest that the comparable 5-ht increase produced by systemic fluoxetine in frontal cortex and dorsal hippocampus results from a greater effect of reuptake blockade in frontal cortex that is offset by a greater autoreceptor-mediated inhibition of 5-ht release. |
2000-06-27 |
2023-08-12 |
rat |
| J Farisse, F Héry, N Barden, M Héry, P Boulengue. Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number. Brain research. vol 862. issue 1-2. 2000-06-21. PMID:10799679. |
we found that 1 nm [3h]8-hydroxy-2-[di-n-propylamino]tetralin ([3h]8-oh-dpat) binding to 5-ht(1a) sites was decreased in strata oriens (-15.1+/-3.5%) and radiatum-lacunosum-moleculare (-13.3+/-4.3%) of the hippocampal ca(3) area, and 2 nm [3h]5-hydroxytryptamine binding to 5-ht(1nona) sites in the presence of 100 nm 8-oh-dpat and mesulergine was decreased in the dorsal subiculum (-17.8+/-6.9%). |
2000-06-21 |
2023-08-12 |
mouse |
| J Farisse, F Héry, N Barden, M Héry, P Boulengue. Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number. Brain research. vol 862. issue 1-2. 2000-06-21. PMID:10799679. |
the observed differences in binding to 5-ht(1) and 5-ht(2) sites were all located in areas of the hippocampus that contain both gluco- and mineralo-corticoid receptors, and no difference was observed in anatomical structures which contain only glucocorticoid receptors. |
2000-06-21 |
2023-08-12 |
mouse |
| I T Uzbay, S E Usanmaz, E S Akars. Effects of chronic ethanol administration on serotonin metabolism in the various regions of the rat brain. Neurochemical research. vol 25. issue 2. 2000-06-14. PMID:10786710. |
changes in serotonin (5-ht) and 5-hydroxy indole acetic acid (5-hiaa), its major metabolite, in cerebral cortex, corpus striatum and hippocampus were investigated at 10th and 21st days of chronic ethanol ingestion in wistar rats. |
2000-06-14 |
2023-08-12 |
rat |
| P H Y. Effect of the Hypericum perforatum extract on serotonin turnover in the mouse brain. Pharmacopsychiatry. vol 33. issue 2. 2000-06-09. PMID:10761821. |
an increase of 5-ht levels was also observed in hypothalamus and hippocampus. |
2000-06-09 |
2023-08-12 |
mouse |
| P Bonaventure, H Hall, W Gommeren, P Cras, X Langlois, M Jurzak, J E Leyse. Mapping of serotonin 5-HT(4) receptor mRNA and ligand binding sites in the post-mortem human brain. Synapse (New York, N.Y.). vol 36. issue 1. 2000-06-02. PMID:10700024. |
comparison of b(max)-values obtained with [(3)h]prucalopride and [(3)h]r116712 indicated that the g-protein coupled fraction of 5-ht(4) receptors in the substantia nigra was exceptionally high (54%) in comparison with percentages (16-27%) found in the frontal cortex, the striatum and the hippocampus. |
2000-06-02 |
2023-08-12 |
human |
| T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758340. |
this immunohistochemical study examined the cellular localization of 5ht(2a) receptors in various rat brain structures (olfactory, striatum, cortex, hippocampus, and amygdala). |
2000-05-31 |
2023-08-12 |
rat |
| T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758340. |
5ht(2a) receptor immunolabeling was observed in olfactory bulbs, neostriatum, hippocampus, amygdala, and neocortex. |
2000-05-31 |
2023-08-12 |
rat |
| T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758340. |
in several other brain structures (hippocampus, amygdala, striatum, olfactory structures), 5ht(2a) receptor immunolabeling was found in cell bodies and processes of neurons. |
2000-05-31 |
2023-08-12 |
rat |
| T Xu, S C Pande. Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758340. |
5ht(2a) receptor immunolabeling was also observed in gfap-positive cells of the various brain structures we investigated (layers i/vi of the neocortex, corpus callosum, hippocampal fissure and hilus, and amygdala). |
2000-05-31 |
2023-08-12 |
rat |
| L Cervo, E Mocaër, A Bertaglia, R Samani. Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727714. |
roles of 5-ht(1a) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-oh-dpat and s 15535 in a modified geller-seifter conflict model. |
2000-05-25 |
2023-08-12 |
Not clear |
| L Cervo, E Mocaër, A Bertaglia, R Samani. Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727714. |
8-oh-dpat [8-hydroxy-2-(di-n-propylamino)tetralin], a 5-ht(1a) receptor agonist, and s 15535 (4-benzodioxan-5-yl)1-(indan-2-yl)piperazine, a partial agonist at 5-ht(1a) receptors, were administered into the dorsal raphe nucleus and dorsal hippocampus and their behavioral effects were assessed in a modified geller-seifter conflict model. |
2000-05-25 |
2023-08-12 |
Not clear |
| L Cervo, E Mocaër, A Bertaglia, R Samani. Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727714. |
the results suggest that stimulation of 5-ht(1a) receptors in the dorsal raphe nucleus has anxiolytic-like effects whereas stimulation of postsynaptic receptors in the dorsal hippocampus has no anxiolytic or anxiogenic effects, at least judging from changes in rates of punished responding. |
2000-05-25 |
2023-08-12 |
Not clear |
| A García-Osta, D Frechilla, J Del Rí. Effect of p-chloroamphetamine on 5-HT1A and 5-HT7 serotonin receptor expression in rat brain. Journal of neurochemistry. vol 74. issue 5. 2000-05-25. PMID:10800921. |
pca (2 x 5 mg/kg) produced a lasting depletion of 5-ht content in the rat frontal cortex and hippocampus. |
2000-05-25 |
2023-08-12 |
rat |
| A García-Osta, D Frechilla, J Del Rí. Effect of p-chloroamphetamine on 5-HT1A and 5-HT7 serotonin receptor expression in rat brain. Journal of neurochemistry. vol 74. issue 5. 2000-05-25. PMID:10800921. |
in the hippocampus, the maximal 5-ht depletion was found on day 21 (-70%), whereas in the cortex, the highest 5-ht depletion was found on day 14 (-73%), with a partial but significant recovery on day 21. |
2000-05-25 |
2023-08-12 |
rat |
| M J Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, J R Seck. Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804232. |
postnatal handling increases the expression of camp-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin. |
2000-05-25 |
2023-08-12 |
rat |
| M J Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, J R Seck. Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804232. |
in primary hippocampal cell cultures, serotonin (5-ht) increases glucocorticoid receptor expression, and this effect appears to be mediated by increased camp levels. |
2000-05-25 |
2023-08-12 |
rat |