| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K G Harikumar, A Chattopadhya. Effect of alcohols on G-protein coupling of serotonin(1A) receptors from bovine hippocampus. Brain research bulletin. vol 52. issue 6. 2000-10-16. PMID:10974502. |
further, we show here that the action of alcohols on the bovine hippocampal 5-ht(1a) receptors could be modulated by guanine nucleotides and that the mode of action of ethanol on the 5-ht(1a) receptor may be quite different than that of other alcohols. |
2000-10-16 |
2023-08-12 |
cattle |
| S Lacosta, Z Merali, H Anisma. Central monoamine activity following acute and repeated systemic interleukin-2 administration. Neuroimmunomodulation. vol 8. issue 2. 2000-10-06. PMID:10965233. |
as well, serotonin (5-hydroxytryptamine; 5-ht) levels were altered within the hippocampus and prefrontal cortex, and dopamine turnover was reduced within the caudate and substantia nigra. |
2000-10-06 |
2023-08-12 |
mouse |
| H M Haughey, A E Fleckenstein, R R Metzger, G R Hanso. The effects of methamphetamine on serotonin transporter activity: role of dopamine and hyperthermia. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987842. |
multiple administrations of methamphetamine (meth) rapidly decreased serotonin (5ht) transporter (sert) function in rat striatum and hippocampus. |
2000-10-05 |
2023-08-12 |
rat |
| R Kohen, D E Heidmann, J Anthony, S S White, M W Hamblin, P Szo. Changes in 5-HT(7) serotonin receptor mRNA expression with aging in rat brain. Brain research. Molecular brain research. vol 79. issue 1-2. 2000-10-04. PMID:10925155. |
in the ventral ca3 area of the hippocampus 5-ht(7) mrna expression is reduced by approximately 30% between young and middle age without further decline between middle and old age. |
2000-10-04 |
2023-08-12 |
rat |
| R Baskar, P U Dev. Influence of gestational age to low-level gamma irradiation on postnatal behavior in mice. Neurotoxicology and teratology. vol 22. issue 4. 2000-10-02. PMID:10974598. |
a representative group of animals was killed and hippocampal biogenic amines, noradrenaline, dopamine, serotonin (5-ht), and 5-ht's metabolite 5-hydroxy indoleactetic acid (5-hiaa), were measured. |
2000-10-02 |
2023-08-12 |
mouse |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: I. in vivo electrophysiological studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884561. |
the effect of a 21-day treatment with the dual 5-ht and ne reuptake blocker venlafaxine (delivered s.c. by osmotic minipumps) was assessed on the time required for a 50% recovery (rt(50)) of the firing activity of dorsal hippocampus ca(3) pyramidal neurons from the suppression induced by microiontophoretic applications of 5-ht and ne. |
2000-09-28 |
2023-08-12 |
rat |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: I. in vivo electrophysiological studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884561. |
using a paradigm by which the 5-ht(1a) antagonist way 100635 can induce a disinhibition of firing activity of ca(3) pyramidal neurons, it was demonstrated that the high, but not the low, dose of venlafaxine led to an enhanced tonic activation of postsynaptic 5-ht(1a) receptors in the dorsal hippocampus. |
2000-09-28 |
2023-08-12 |
rat |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884562. |
the effects of long-term administrations of a low (10 mg/kg/day) and a high (40 mg/kg/day) dose of the dual 5-ht and ne reuptake inhibitor venlafaxine (delivered s.c. by osmotic minipumps for 21 days) were assessed on the electrically-evoked release of tritium from hippocampal slices preloaded with either [(3)h]5-ht or [(3)h]ne, 48 h after the removal of the minipump. |
2000-09-28 |
2023-08-12 |
rat |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884562. |
none of the treatment regimens altered the basal uptake of [(3)h]5-ht from hippocampal or mesencephalic slices nor that of [(3)h]ne from hippocampal slices. |
2000-09-28 |
2023-08-12 |
rat |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884562. |
finally, the enhancing effect of 1 microm of paroxetine in the perfusion medium on the electrical release of [(3)h]5-ht was unaltered in hippocampal slices prepared from rats that had been treated for 21 days with 40 mg/kg/day of venlafaxine. |
2000-09-28 |
2023-08-12 |
rat |
| C Martin, M Duclos, P Mormède, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters. vol 288. issue 3. 2000-09-28. PMID:10889353. |
hippocampal and striatal [(3)h]5-ht reuptake under acute stressors in two rat strains differing for their emotivity. |
2000-09-28 |
2023-08-12 |
rat |
| C Martin, M Duclos, P Mormède, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters. vol 288. issue 3. 2000-09-28. PMID:10889353. |
since the 5-ht transporter plays a key role in 5-ht neurotransmission, we have analyzed whether hippocampal and/or striatal [(3)h]5-ht reuptake kinetics are altered by stress in a strain-dependent manner. |
2000-09-28 |
2023-08-12 |
rat |
| C Martin, M Duclos, P Mormède, G Manier, F Chaoulof. Hippocampal and striatal [(3)H]5-HT reuptake under acute stressors in two rat strains differing for their emotivity. Neuroscience letters. vol 288. issue 3. 2000-09-28. PMID:10889353. |
it was found that forced swimming, treadmill running, or restraint for 30 min affected neither hippocampal nor striatal [(3)h]5-ht reuptake k(m) and v(max) values in the two rat strains. |
2000-09-28 |
2023-08-12 |
rat |
| E Dremencov, E Gur, B Lerer, M E Newma. Subchronic fluoxetine administration to rats: effects on 5-HT autoreceptor activity as measured by in vivo microdialysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 4. 2000-09-14. PMID:10871704. |
to rats for 6 days on presynaptic 5-ht(1a) receptor activity in the hypothalamus, postsynaptic 5-ht(1a) receptor activity in the hippocampus, and presynaptic 5-ht(1b) autoreceptor activity in both areas, using in vivo microdialysis. |
2000-09-14 |
2023-08-12 |
rat |
| E Dremencov, E Gur, B Lerer, M E Newma. Subchronic fluoxetine administration to rats: effects on 5-HT autoreceptor activity as measured by in vivo microdialysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 4. 2000-09-14. PMID:10871704. |
the effect of the 5-ht(1b/1d) antagonist (n-[4-methoxy-3-(4-methyl-1-piperizinyl)phenyl]-2'-methyl-4'-(5- methyl-1,2,4-oxadiazole-3-yl)[1,1'-biphenyl]-carboxamide (gr 127935) (5 mg/kg s.c.) to elevate 5-hydroxytryptamine (5-ht) levels was reduced in hippocampus but not hypothalamus of fluoxetine-treated rats. |
2000-09-14 |
2023-08-12 |
rat |
| E Dremencov, E Gur, B Lerer, M E Newma. Subchronic fluoxetine administration to rats: effects on 5-HT autoreceptor activity as measured by in vivo microdialysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 4. 2000-09-14. PMID:10871704. |
fluoxetine did not alter either presynaptic 5-ht(1a) autoreceptor activity, as measured by the effect of injection of 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat) (0.2 mg/kg or 50 microg/kg s.c.) on 5-ht levels in the hypothalamus, or postsynaptic 5-ht(1a) receptor activity, as measured by the effect of 8-oh-dpat (0.2 mg/kg s.c.) on cyclic amp accumulation, in the hippocampus. |
2000-09-14 |
2023-08-12 |
rat |
| D J Halee. Attenuation of 8-OH-DPAT-induced decreases in 5-Ht synthesis in brain regions of rats adapted to a repeated stress schedule. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938574. |
the drug injected systemically at a dose of 1 mg/kg decreased 5-ht synthesis in the hypothalamus, cortex, hippocampus, striatum and raphe regions of previously unrestrained rats. |
2000-09-14 |
2023-08-12 |
rat |
| I Hervías, B Lasheras, N Aguirr. 2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity. Journal of neurochemistry. vol 75. issue 3. 2000-09-12. PMID:10936179. |
2-dg had no effect on 5-ht concentrations in the frontal cortex, hippocampus, and striatum but prevented the neurotoxicity induced by mdma. |
2000-09-12 |
2023-08-12 |
rat |
| K E Sabol, J B Richards, K Yun. The effects of high-dose methamphetamine in the aging rat: differential reinforcement of low-rate 72-s schedule behavior and neurochemistry. The Journal of pharmacology and experimental therapeutics. vol 294. issue 3. 2000-09-12. PMID:10945833. |
at age 70 weeks, serotonin concentrations were decreased in somatosensory cortex, occipital cortex, and hippocampus but not in other subcortical structures. |
2000-09-12 |
2023-08-12 |
rat |
| K E Sabol, J B Richards, K Yun. The effects of high-dose methamphetamine in the aging rat: differential reinforcement of low-rate 72-s schedule behavior and neurochemistry. The Journal of pharmacology and experimental therapeutics. vol 294. issue 3. 2000-09-12. PMID:10945833. |
serotonin depletions were noted in cortex, hippocampus, amygdala, and striatum but not in septum, hypothalamus, nucleus accumbens/olfactory tubercle, or ventral midbrain. |
2000-09-12 |
2023-08-12 |
rat |