| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F C Colpaert, L A Bruins Slot, W Koek, D S Dupui. Memory of an operant response and of depressed mood retained in activation states of 5-HT(1A) receptors: evidence from rodent models. Behavioural brain research. vol 117. issue 1-2. 2001-02-08. PMID:11099756. |
first, in vitro studies of [35s]gtpgammas binding responses identified ligands that differentially activate 5-ht(1a) receptors in rat hippocampus. |
2001-02-08 |
2023-08-12 |
rat |
| E Gur, E Dremencov, B Lerer, M E Newma. Functional effects of corticosterone on 5-HT(1A) and 5-HT(1B) receptor activity in rat brain: in vivo microdialysis studies. European journal of pharmacology. vol 411. issue 1-2. 2001-02-08. PMID:11137865. |
presynaptic 5-ht(1b) receptor activity, as measured by the effect of the 5-ht(1b) receptor antagonist (n-[4-methoxy-3-(4-methyl-1-piperizinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazole-3-yl)[1,1'-biphenyl]-carboxamide (gr 127935) (5 mg/kg s.c.) to increase 5-ht levels, was increased in hypothalamus but not hippocampus of corticosterone-treated rats. |
2001-02-08 |
2023-08-12 |
rat |
| E Gur, E Dremencov, B Lerer, M E Newma. Functional effects of corticosterone on 5-HT(1A) and 5-HT(1B) receptor activity in rat brain: in vivo microdialysis studies. European journal of pharmacology. vol 411. issue 1-2. 2001-02-08. PMID:11137865. |
postsynaptic 5-ht(1a) receptor activity, as measured by the effect of 8-oh-dpat to increase cyclic amp levels in the hippocampus, was not affected by corticosterone administration. |
2001-02-08 |
2023-08-12 |
rat |
| A J Ramos, P Tagliaferro, E M López, J Pecci Saavedra, A Brusc. Neuroglial interactions in a model of para-chlorophenylalanine-induced serotonin depletion. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063982. |
s-100beta, 5ht, 5ht-transporter (5ht-t) and neurofilaments (nf-200 and nf-68) expressions were studied by immunohistochemistry and image analysis in striatum, hippocampus, parietal and frontal cortex. |
2001-02-01 |
2023-08-12 |
rat |
| C Schaper, Y Zhu, M Kouklei, C Culmsee, J Krieglstei. Stimulation of 5-HT(1A) receptors reduces apoptosis after transient forebrain ischemia in the rat. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063986. |
taken together, the results suggest that bay x 3702 can rescue hippocampal as well as striatal neurons from apoptotic cell death in vivo via stimulation of 5-ht(1a) receptors. |
2001-02-01 |
2023-08-12 |
rat |
| T Kakiuchi, S Nishiyama, K Sato, H Ohba, S Nakanishi, H Tsukad. Age-related reduction of [11C]MDL100,907 binding to central 5-HT(2A) receptors: PET study in the conscious monkey brain. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063997. |
higher cerebral binding of [11c]mdl100, 907 was observed in the hippocampus, cingulate gyrus, frontal, temporal and occipital cortices, regions known to contain high densities of 5-ht(2a), by in vitro assay. |
2001-02-01 |
2023-08-12 |
monkey |
| T Kakiuchi, S Nishiyama, K Sato, H Ohba, S Nakanishi, H Tsukad. Age-related reduction of [11C]MDL100,907 binding to central 5-HT(2A) receptors: PET study in the conscious monkey brain. Brain research. vol 883. issue 1. 2001-02-01. PMID:11063997. |
the age-related decrease in [11c]mdl100,907 binding to 5-ht(2a) receptors was prominent in the hippocampus, cingulate gyrus, frontal, temporal and occipital cortices, but not in the striatum, thalamus and pons. |
2001-02-01 |
2023-08-12 |
monkey |
| C A Heidbreder, I C Weiss, A M Domeney, C Pryce, J Homberg, G Hedou, J Feldon, M C Moran, P Nelso. Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome. Neuroscience. vol 100. issue 4. 2001-01-18. PMID:11036209. |
in addition, ex vivo neurochemical changes in the brains of isolated and grouped rats reared either in sawdust-lined or in grid-floor cages were determined by measuring dopamine and serotonin as well as their major metabolites in a "psychosis circuit" that includes mainly the hippocampus and selected hippocampal efferent pathways projecting towards the anterior cingulate and infralimbic cortices, nucleus accumbens, dorsolateral caudate nucleus, amygdala and entorhinal cortex. |
2001-01-18 |
2023-08-12 |
rat |
| B Ladenheim, I N Krasnova, X Deng, J M Oyler, A Polettini, T H Moran, M A Huestis, J L Cade. Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6. Molecular pharmacology. vol 58. issue 6. 2001-01-18. PMID:11093760. |
meth also caused a decrease in serotonin levels in the cpu and hippocampus of wild-type mice, but no reduction was observed in il-6-/- animals. |
2001-01-18 |
2023-08-12 |
mouse |
| E Consogno, G Racagni, M Popol. Modifications in brain CaM kinase II after long-term treatment with desmethylimipramine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 1. 2001-01-18. PMID:11106872. |
similar to selective and non-selective serotonin reuptake inhibitors, long-term, but not acute, treatment with desmethylimipramine markedly increased the activity of camkii in the hippocampal synaptic vesicle fraction (+51.9%). |
2001-01-18 |
2023-08-12 |
Not clear |
| S D Norrholm, C C Ouime. Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus. Brain research. vol 883. issue 2. 2001-01-09. PMID:11074049. |
significant alterations in hippocampal levels of serotonin and norepinephrine impact synaptic development during this time period. |
2001-01-09 |
2023-08-12 |
rat |
| S D Norrholm, C C Ouime. Chronic fluoxetine administration to juvenile rats prevents age-associated dendritic spine proliferation in hippocampus. Brain research. vol 883. issue 2. 2001-01-09. PMID:11074049. |
in the present study, dendritic spine density was studied in the hippocampus (ca1) and dentate gyrus of juvenile rats acutely and chronically exposed to antidepressant drugs that act on serotonin and norepinephrine. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
influence of thyroid hormone on 5-ht(1a) and 5-ht(2a) receptor-mediated regulation of hippocampal bdnf mrna expression. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
chronic t3 administration prior to treatment with the 5-ht(1a) agonist, 8-oh-dpat, significantly decreased bdnf mrna in the dentate gyrus region of the hippocampus. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
acute or chronic administration of t3 did not alter the decrease in hippocampal bdnf mrna induced by the 5-ht(2a/2c) receptor agonist, doi. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
the affinity and density of 5-ht(1a) receptors, and the hippocampal expression of 5-ht(1a) mrna were also not influenced by chronic t3 treatment. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
the results of this study clearly demonstrate a powerful interaction between thyroid hormone and the 5-ht(1a) receptor in the regulation of hippocampal bdnf expression. |
2001-01-09 |
2023-08-12 |
rat |
| V A Vaidya, M E Castro, Q Pei, M E Sprakes, D G Grahame-Smit. Influence of thyroid hormone on 5-HT(1A) and 5-HT(2A) receptor-mediated regulation of hippocampal BDNF mRNA expression. Neuropharmacology. vol 40. issue 1. 2001-01-09. PMID:11077070. |
crosstalk between signal transduction cascades influenced by t3 and 5-ht(1a) receptors may mediate the synergistic effects of these systems on hippocampal bdnf expression. |
2001-01-09 |
2023-08-12 |
rat |
| J M Casanovas, O Berton, P Celada, F Artiga. In vivo actions of the selective 5-HT1A receptor agonist BAY x 3702 on serotonergic cell firing and release. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997727. |
in microdialysis experiments, bay x 3702 (10-100 microg/ kg s.c.) reduced dose-dependently the 5-ht output in the dorsal and median raphe (mnr) nucleus, dorsal hippocampus (dhpc) and medial prefrontal cortex (mpfc) in a regionally selective manner. |
2001-01-05 |
2023-08-12 |
rat |
| M Yamada, M Yamada, S Yamazaki, K Takahashi, G Nishioka, K Kudo, H Ozawa, S Yamada, Y Kiuchi, K Kamijima, T Higuchi, K Momos. Identification of a novel gene with RING-H2 finger motif induced after chronic antidepressant treatment in rat brain. Biochemical and biophysical research communications. vol 278. issue 1. 2001-01-04. PMID:11071867. |
with this microarray, we found that the expression of a novel gene, adrg34, was significantly increased in rat hippocampus which had been chronically treated with a selective serotonin reuptake inhibitor antidepressant, sertraline. |
2001-01-04 |
2023-08-12 |
mouse |