| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Ravi, B M Prabhu, T R Raju, P N Bind. Long-term effects of postnatal aluminium exposure on acetylcholinesterase activity and biogenic amine neurotransmitters in rat brain. Indian journal of physiology and pharmacology. vol 44. issue 4. 2001-04-12. PMID:11214504. |
in the aluminium exposed group: the ache activity was significantly decreased in the hippocampus, septum, striatum and brainstem; serotonin levels were reduced by 20% in the cortex, hippocampus, septum and striatum; in brain stem, the serotonin level was decreased by 40%. |
2001-04-12 |
2023-08-12 |
human |
| M J Millan, F Lejeune, G De Nanteuil, A Gober. Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats. Journal of neurochemistry. vol 76. issue 6. 2001-04-12. PMID:11259513. |
in the dorsal hippocampus, gr205,171 (but not gr226,206) also significantly increased dialysate levels of na, whereas levels of 5-ht were unaffected. |
2001-04-12 |
2023-08-12 |
rat |
| M Okada, D J Nutt, T Murakami, G Zhu, A Kamata, Y Kawata, S Kanek. Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 2. 2001-04-05. PMID:11160442. |
adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release. |
2001-04-05 |
2023-08-12 |
rat |
| M Okada, D J Nutt, T Murakami, G Zhu, A Kamata, Y Kawata, S Kanek. Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 2. 2001-04-05. PMID:11160442. |
to clarify the mechanisms of interaction between adenosine a(1) receptor (a1-r) and adenosine a(2) receptor (a2-r) on neurotransmitter release, this study determined the functional interactions among adenosine receptors (ad-rs), voltage-sensitive ca(2+) channels (vsccs), protein kinases (pks), and synaptic proteins [n-ethylmaleimide-sensitive factor (nsf) attachment protein (snap) receptors] on hippocampal serotonin release using in vivo microdialysis in freely moving rat. |
2001-04-05 |
2023-08-12 |
rat |
| M Okada, D J Nutt, T Murakami, G Zhu, A Kamata, Y Kawata, S Kanek. Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 2. 2001-04-05. PMID:11160442. |
therefore, pka activity plays an important role in the interaction between a1-r and a2-r on hippocampal serotonin release. |
2001-04-05 |
2023-08-12 |
rat |
| H J Bengtsson, J Kele, J Johansson, S Hjort. Interaction of the antidepressant mirtazapine with alpha2-adrenoceptors modulating the release of 5-HT in different rat brain regions in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 4-5. 2001-03-29. PMID:11111835. |
probes were implanted in the dorsal hippocampus (dh) and frontal cortex (fcx), representing median and dorsal raphe 5-ht projection areas, respectively. |
2001-03-29 |
2023-08-12 |
rat |
| E B Arushunian, E V Beĭe. [The role for the hippocampus in the biorhythmical behavior]. Uspekhi fiziologicheskikh nauk. vol 32. issue 1. 2001-03-29. PMID:11234437. |
psychotropic drugs (anxiolytics and antidepressants) by means of intensified of hippocampal inhibitory mechanisms (previously gaba and 5-ht) are stabilized of biorhythms what determined their specific anxiolytic and antidepressant effects. |
2001-03-29 |
2023-08-12 |
Not clear |
| I Malagié, A C Trillat, M Bourin, C Jacquot, R Hen, A M Gardie. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158258. |
5-ht1b autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. |
2001-03-15 |
2023-08-12 |
mouse |
| I Malagié, A C Trillat, M Bourin, C Jacquot, R Hen, A M Gardie. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158258. |
increased extracellular serotonin levels [5-ht]ext in the ventral hippocampus and frontal cortex of wild-type and mutant mice. |
2001-03-15 |
2023-08-12 |
mouse |
| I Malagié, A C Trillat, M Bourin, C Jacquot, R Hen, A M Gardie. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158258. |
however, in the ventral hippocampus, paroxetine at the two doses studied induced a larger increase in [5-ht]ext in knockout than in wild-type mice. |
2001-03-15 |
2023-08-12 |
mouse |
| I Malagié, A C Trillat, M Bourin, C Jacquot, R Hen, A M Gardie. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158258. |
in addition, either the absence of the 5-ht1b receptor or its blockade with the mixed 5-ht1b/1d receptor antagonist, gr 127935, potentiated the effect of a single administration of paroxetine on extracellular 5-ht levels more in the ventral hippocampus than in the frontal cortex. |
2001-03-15 |
2023-08-12 |
mouse |
| R Kuczenski, D S Sega. Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. The Journal of pharmacology and experimental therapeutics. vol 296. issue 3. 2001-03-15. PMID:11181919. |
the relative roles of dopamine, norepinephrine, and serotonin in the therapeutic action of these drugs was assessed by comparing the responses of extracellular nucleus accumbens dopamine and serotonin and hippocampus norepinephrine to the acute administration of low methylphenidate and amphetamine doses. |
2001-03-15 |
2023-08-12 |
Not clear |
| G Gobbi, D L Murphy, K Lesch, P Blie. Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. The Journal of pharmacology and experimental therapeutics. vol 296. issue 3. 2001-03-15. PMID:11181933. |
at the postsynaptic level, the recovery time (rt(50)) of the firing rate of hippocampus ca(3) pyramidal neurons following iontophoretic applications of 5-ht was significantly prolonged only in 5-htt -/- mice. |
2001-03-15 |
2023-08-12 |
mouse |
| H Takeda, M Tsuji, T Matsumiy. [Formation mechanisms of stress adaptation: role of functional coupling of glucocorticoids and brain serotonergic nervous system]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 20. issue 3. 2001-03-15. PMID:11215154. |
given the high sensitivity of hippocampal 5-ht responses to glucocorticoids, functional changes in the hippocampal 5-ht nervous system induced by chronic hypercorticism are attracting more attention. |
2001-03-15 |
2023-08-12 |
Not clear |
| P Whitaker-Azmitia, F Zhou, J Hobin, A Borell. Isolation-rearing of rats produces deficits as adults in the serotonergic innervation of hippocampus. Peptides. vol 21. issue 11. 2001-03-01. PMID:11090932. |
our findings show that serotonin terminals are lost throughout the ca regions of hippocampus, where there is also an associated loss of dendrites, but not in the molecular layer of the dentate gyrus. |
2001-03-01 |
2023-08-12 |
rat |
| R M Sibug, J C Compaan, O C Meijer, J Van der Gugten, B Olivier, E R De Kloe. Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus. European journal of pharmacology. vol 404. issue 1-2. 2001-02-22. PMID:10980269. |
we have studied the effect of the specific 5-hydroxytryptamine, 5-ht(1a), receptor agonist flesinoxan on mrna for glucocorticoid and mineralocorticoid receptors in the hippocampus and dorsal raphe nucleus. |
2001-02-22 |
2023-08-12 |
rat |
| R M Sibug, J C Compaan, O C Meijer, J Van der Gugten, B Olivier, E R De Kloe. Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus. European journal of pharmacology. vol 404. issue 1-2. 2001-02-22. PMID:10980269. |
these data indicate that the 5-ht(1a) receptor agonist flesinoxan alters glucocorticoid receptor expression via a direct pathway independently of corticosterone and argues for an intrinsic effect selective for hippocampal glucocorticoid receptor mrna. |
2001-02-22 |
2023-08-12 |
rat |
| M Carli, C Balducci, R Samani. Low doses of 8-OH-DPAT prevent the impairment of spatial learning caused by intrahippocampal scopolamine through 5-HT(1A) receptors in the dorsal raphe. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991934. |
we studied the effects of low doses of 8-oh-dpat, a 5-ht(1a) receptor agonist, on the impairment of spatial learning caused by scopolamine injected into the ca1 region of the dorsal hippocampus of rats performing a two-platform spatial discrimination task. |
2001-02-22 |
2023-08-12 |
rat |
| M Carli, C Balducci, R Samani. Low doses of 8-OH-DPAT prevent the impairment of spatial learning caused by intrahippocampal scopolamine through 5-HT(1A) receptors in the dorsal raphe. British journal of pharmacology. vol 131. issue 2. 2001-02-22. PMID:10991934. |
drugs that stimulate presynaptic 5-ht(1a) receptors such as 5-ht(1a) receptor partial agonists may be useful in the symptomatic treatment of human memory disturbances associated with loss of cholinergic innervation to the hippocampus. |
2001-02-22 |
2023-08-12 |
rat |
| J F Neumaier, T J Sexton, M W Hamblin, S G Bec. Corticosteroids regulate 5-HT(1A) but not 5-HT(1B) receptor mRNA in rat hippocampus. Brain research. Molecular brain research. vol 82. issue 1-2. 2001-02-22. PMID:11042358. |
corticosteroids regulate 5-ht(1a) but not 5-ht(1b) receptor mrna in rat hippocampus. |
2001-02-22 |
2023-08-12 |
rat |