| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
local perfusion of odq (400 microm) did not affect 5-ht overflow in the hippocampus. |
2000-08-01 |
2023-08-12 |
rat |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
we conclude that nos inhibitors increased extracellular levels of 5-ht and da in the rat ventral hippocampus after local or systemic administration, whereas the no precursor l-arg had the opposite effect. |
2000-08-01 |
2023-08-12 |
rat |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
thus, endogenous no may exert a negative control over the levels of 5-ht and da in the hippocampus. |
2000-08-01 |
2023-08-12 |
rat |
| T R Madhav, Q Pei, D G Grahame-Smith, T S Zetterströ. Repeated electroconvulsive shock promotes the sprouting of serotonergic axons in the lesioned rat hippocampus. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842012. |
this study reports the effect of repeated electroconvulsive shock on the sprouting of 5-hydroxytryptamine neurons in the partly lesioned rat dorsal hippocampus. |
2000-07-24 |
2023-08-12 |
rat |
| T R Madhav, Q Pei, D G Grahame-Smith, T S Zetterströ. Repeated electroconvulsive shock promotes the sprouting of serotonergic axons in the lesioned rat hippocampus. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842012. |
we have adopted a 5-hydroxytryptamine homotypic collateral sprouting model to examine whether electroconvulsive shock administration altered the rate of 5-hydroxytryptamine axonal reinnervation of the dorsal hippocampus. |
2000-07-24 |
2023-08-12 |
rat |
| T R Madhav, Q Pei, D G Grahame-Smith, T S Zetterströ. Repeated electroconvulsive shock promotes the sprouting of serotonergic axons in the lesioned rat hippocampus. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842012. |
the 5-hydroxytryptamine innervation of hippocampus originates from the median raphe via the cingulum bundle and the fimbria-fornix. |
2000-07-24 |
2023-08-12 |
rat |
| T R Madhav, Q Pei, D G Grahame-Smith, T S Zetterströ. Repeated electroconvulsive shock promotes the sprouting of serotonergic axons in the lesioned rat hippocampus. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842012. |
rats were unilaterally injected with the 5-hydroxytryptamine neurotoxin, 5,7-dihydroxytryptamine, into the right cingulum bundle and 5-hydroxytryptamine immunoreactivity in the dorsal hippocampus was investigated 1, 3, 6 and 12weeks after the injection. |
2000-07-24 |
2023-08-12 |
rat |
| T R Madhav, Q Pei, D G Grahame-Smith, T S Zetterströ. Repeated electroconvulsive shock promotes the sprouting of serotonergic axons in the lesioned rat hippocampus. Neuroscience. vol 97. issue 4. 2000-07-24. PMID:10842012. |
the present data provide the first direct evidence that electroconvulsive shock enhances 5-hydroxytryptamine axon sprouting in the partly lesioned hippocampus. |
2000-07-24 |
2023-08-12 |
rat |
| L Trabace, T Cassano, L Steardo, C Pietra, G Villetti, K M Kendrick, V Cuom. Biochemical and neurobehavioral profile of CHF2819, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease. The Journal of pharmacology and experimental therapeutics. vol 294. issue 1. 2000-07-24. PMID:10871311. |
furthermore, chf2819 induces a significant decrease in dopamine levels and a significant elevation of extracellular concentrations of 5-hydroxytryptamine, whereas it does not modify norepinephrine and gamma-aminobutyric acid levels in the hippocampus of young adult rats. |
2000-07-24 |
2023-08-12 |
rat |
| S Puglisi-Allegra, S Cabib, T Pascucci, R Ventura, F Cali, V Roman. Dramatic brain aminergic deficit in a genetic mouse model of phenylketonuria. Neuroreport. vol 11. issue 6. 2000-07-17. PMID:10817622. |
results indicated a significant reduction of 5-ht levels and metabolism in prefrontal cortex (pfc), cingulate cortex (cg), nucleus accumbens (nac), caudate putamen (cp), hippocampus (hip) and amygdala (amy). |
2000-07-17 |
2023-08-12 |
mouse |
| H Husum, J D Mikkelsen, S Hogg, A A Mathé, A Mør. Involvement of hippocampal neuropeptide Y in mediating the chronic actions of lithium, electroconvulsive stimulation and citalopram. Neuropharmacology. vol 39. issue 8. 2000-07-12. PMID:10818262. |
consequently, parameters reflective of npyergic neurotransmission were studied in the hippocampus of rats following chronic treatment with lithium, ecs or the selective serotonin re-uptake inhibitor (ssri), citalopram. |
2000-07-12 |
2023-08-12 |
rat |
| J Sprouse, J Braselton, L Reynold. 5-HT(1A) agonist potential of pindolol: electrophysiologic studies in the dorsal raphe nucleus and hippocampus. Biological psychiatry. vol 47. issue 12. 2000-07-12. PMID:10862804. |
5-ht(1a) agonist potential of pindolol: electrophysiologic studies in the dorsal raphe nucleus and hippocampus. |
2000-07-12 |
2023-08-12 |
Not clear |
| J Sprouse, J Braselton, L Reynold. 5-HT(1A) agonist potential of pindolol: electrophysiologic studies in the dorsal raphe nucleus and hippocampus. Biological psychiatry. vol 47. issue 12. 2000-07-12. PMID:10862804. |
previous investigators have probed the effects of pindolol on serotonergic dorsal raphe cell firing in animal species; here we confirm their findings and extend them to include observations on postsynaptic 5-ht(1a) receptors in the hippocampus. |
2000-07-12 |
2023-08-12 |
Not clear |
| S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior. vol 66. issue 1. 2000-07-06. PMID:10837844. |
a review of the literature suggests that the dorsal hippocampal serotonergic system, and, in particular, the postsynaptic 5-ht(1a) receptor, mediates an anxiogenic response, whereas endogenous dorsal hippocampal cholinergic tone mediates an anxiolytic response. |
2000-07-06 |
2023-08-12 |
rat |
| S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior. vol 66. issue 1. 2000-07-06. PMID:10837844. |
accordingly, it has been shown that direct dorsal hippocampal administration of the 5-ht(1a) receptor agonist, 8-oh-dpat, the nicotinic receptor antagonist, mecamylamine, and the m(1) muscarinic receptor antagonist, pirenzepine, all have anxiogenic effects in rats tested in the social interaction test. |
2000-07-06 |
2023-08-12 |
rat |
| S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior. vol 66. issue 1. 2000-07-06. PMID:10837844. |
however, the anxiogenic effects of mecamylamine and nicotine in the dorsal hippocampus are blocked by coadministration of the 5-ht(1a) receptor antagonist, way 100635, suggesting that both of these compounds act by enhancing hippocampal serotonergic transmission, thereby stimulating postsynaptic 5-ht(1a) receptors. |
2000-07-06 |
2023-08-12 |
rat |
| S E File, P J Kenny, S Cheet. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, biochemistry, and behavior. vol 66. issue 1. 2000-07-06. PMID:10837844. |
a possible mechanism by which nicotinic receptor ligands modulate hippocampal 5-ht release is discussed, and it is proposed that the dorsal hippocampal serotonergic and cholinergic systems are tightly coupled and function antagonistically in the modulation of anxiety, as measured in the social interaction test. |
2000-07-06 |
2023-08-12 |
rat |
| D J Balfour, D L Ridle. The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? Pharmacology, biochemistry, and behavior. vol 66. issue 1. 2000-07-06. PMID:10837846. |
the review also explores the possibility that chronic exposure to nicotine elicits changes in 5-ht formation and release in the hippocampus which are depressogenic. |
2000-07-06 |
2023-08-12 |
Not clear |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
role of uptake inhibition and autoreceptor activation in the control of 5-ht release in the frontal cortex and dorsal hippocampus of the rat. |
2000-06-27 |
2023-08-12 |
rat |
| I Hervás, C M Queiroz, A Adell, F Artiga. Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. British journal of pharmacology. vol 130. issue 1. 2000-06-27. PMID:10781012. |
doubled the 5-ht output in frontal cortex and dorsal hippocampus. |
2000-06-27 |
2023-08-12 |
rat |