| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sémont, M Fache, F Héry, M Faudon, F Youssouf, M Hér. Regulation of central corticosteroid receptors following short-term activation of serotonin transmission by 5-hydroxy-L-tryptophan or fluoxetine. Journal of neuroendocrinology. vol 12. issue 8. 2000-09-06. PMID:10929085. |
these results show that short-term stimulation of 5-ht transmission by 5-htp decreases hippocampal and hypothalamic corticosteroid receptor numbers through a corticosterone-independent mechanism. |
2000-09-06 |
2023-08-12 |
rat |
| M A Cenci, P Kalé. Serotonin release from mesencephalic raphe neurons grafted to the 5,7-dihydroxytryptamine-lesioned rat hippocampus: effects of behavioral activation and stress. Experimental neurology. vol 164. issue 2. 2000-08-31. PMID:10915574. |
serotonin release from mesencephalic raphe neurons grafted to the 5,7-dihydroxytryptamine-lesioned rat hippocampus: effects of behavioral activation and stress. |
2000-08-31 |
2023-08-12 |
rat |
| T I Cremers, P de Boer, Y Liao, F J Bosker, J A den Boer, B H Westerink, H V Wikströ. Augmentation with a 5-HT(1A), but not a 5-HT(1B) receptor antagonist critically depends on the dose of citalopram. European journal of pharmacology. vol 397. issue 1. 2000-08-29. PMID:10844100. |
citalopram dose-dependently (0.3-10 micromol/kg s.c.) increased serotonin levels in ventral hippocampus of conscious rats. |
2000-08-29 |
2023-08-12 |
rat |
| H Takahashi, Y Takada, N Nagai, T Urano, A Takad. Serotonergic neurons projecting to hippocampus activate locomotion. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865074. |
thus, using microdialysis and microinjection techniques, we examined the relationship between serotonin (5-ht) levels in striatum, hippocampus or prefrontal cortex (pfc) and motor activity in rats. |
2000-08-25 |
2023-08-12 |
rat |
| H Takahashi, Y Takada, N Nagai, T Urano, A Takad. Serotonergic neurons projecting to hippocampus activate locomotion. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865074. |
of monoamine oxidase inhibitor, tranylcypromine (tc), significantly elevated 5-ht levels in the striatum, hippocampus and pfc accompanied by a parallel increase in motor activity of the rats. |
2000-08-25 |
2023-08-12 |
rat |
| W L Bacon, S G Bec. 5-Hydroxytryptamine(7) receptor activation decreases slow afterhyperpolarization amplitude in CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 294. issue 2. 2000-08-24. PMID:10900247. |
the 5-ht(7) receptor protein and mrna are found in brain areas, such as the ca3 subfield of the hippocampus, that are involved in various neuropsychiatric disease states. |
2000-08-24 |
2023-08-12 |
Not clear |
| T M Cabrera-Vera, F Garcia, W Pinto, G Battagli. Neurochemical changes in brain serotonin neurons in immature and adult offspring prenatally exposed to cocaine. Brain research. vol 870. issue 1-2. 2000-08-21. PMID:10869495. |
neurochemical changes in frontal cortex, hypothalamus, hippocampus, striatum and midbrain of prepubescent and adult offspring were determined by measuring: (1) the content of serotonin (5-ht) and its major metabolite 5-hydroxyindolacetic acid (5-hiaa), and (2) the ability of the serotonin releasing drug p-chloroamphetamine (pca) to reduce brain serotonin levels. |
2000-08-21 |
2023-08-12 |
rat |
| T M Cabrera-Vera, F Garcia, W Pinto, G Battagli. Neurochemical changes in brain serotonin neurons in immature and adult offspring prenatally exposed to cocaine. Brain research. vol 870. issue 1-2. 2000-08-21. PMID:10869495. |
however, in adult progeny prenatally exposed to cocaine, basal 5-ht content was significantly reduced in the frontal cortex (-32%) and hippocampus (-40%), suggesting maturation-dependent effects of prenatal cocaine exposure on brain 5-ht neurons. |
2000-08-21 |
2023-08-12 |
rat |
| H C Akunne, K T Zoski, M D Davis, L W Cooke, L T Meltzer, S Z Whetzel, Y H Shih, D J Wustrow, L D Wise, R G MacKenzie, L M Georgic, T G Heffner, T A Pugsle. PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects. Neuropharmacology. vol 39. issue 7. 2000-08-15. PMID:10760362. |
pd 158771 showed high affinity for cloned human 5-ht(1a) (k(i) = 2.6 nm) and rat hippocampal 5-ht(1a) receptors (k(i) = 3.5 nm). |
2000-08-15 |
2023-08-12 |
human |
| B J Keck, J M Lakosk. Regional heterogeneity of serotonin(1A) receptor inactivation and turnover in the aging female rat brain following EEDQ. Neuropharmacology. vol 39. issue 7. 2000-08-15. PMID:10760365. |
equilibrium binding analyses for the 5-ht(1a) receptor binding site incorporated [(3)h]8-hydroxy-2-(di-n-propylamino)tetralin ([(3)h]8-oh-dpat) and were conducted in the frontal cortex, amygdala and hippocampus at 1, 2, 7 and 14 days after treatment with eedq (6.0 mg/kg, s.c.) or vehicle. |
2000-08-15 |
2023-08-12 |
rat |
| J P Anthony, T J Sexton, J F Neumaie. Antidepressant-induced regulation of 5-HT(1b) mRNA in rat dorsal raphe nucleus reverses rapidly after drug discontinuation. Journal of neuroscience research. vol 61. issue 1. 2000-08-14. PMID:10861803. |
in this study we examined longer term treatment (8 weeks) with several different serotonin-selective reuptake inhibitors (ssris) or a tricyclic antidepressant on 5-ht(1b) mrna regulation in drn and hippocampus, and evaluated the stability of these drugs' effects after drug discontinuation. |
2000-08-14 |
2023-08-12 |
rat |
| J P Anthony, T J Sexton, J F Neumaie. Antidepressant-induced regulation of 5-HT(1b) mRNA in rat dorsal raphe nucleus reverses rapidly after drug discontinuation. Journal of neuroscience research. vol 61. issue 1. 2000-08-14. PMID:10861803. |
5-ht(1b) mrna levels in hippocampus were not affected by ssri drugs at any timepoint. |
2000-08-14 |
2023-08-12 |
rat |
| J P Anthony, T J Sexton, J F Neumaie. Antidepressant-induced regulation of 5-HT(1b) mRNA in rat dorsal raphe nucleus reverses rapidly after drug discontinuation. Journal of neuroscience research. vol 61. issue 1. 2000-08-14. PMID:10861803. |
nortriptyline had no significant effect on 5-ht(1b) mrna in either drn or hippocampus. |
2000-08-14 |
2023-08-12 |
rat |
| B Shapira, M E Newman, Y Gelfin, B Lere. Blunted temperature and cortisol responses to ipsapirone in major depression: lack of enhancement by electroconvulsive therapy. Psychoneuroendocrinology. vol 25. issue 5. 2000-08-03. PMID:10818278. |
in contrast to the effects of electroconvulsive shock (ecs) on post-synaptic 5-ht(1a) receptor function in animals, which have chiefly been measured in the hippocampus using electrophysiological techniques, ect in humans does not induce an increase in sensitivity of post-synaptic 5-ht(1a) receptors in the hypothalamus. |
2000-08-03 |
2023-08-12 |
human |
| A Besson, N Haddjeri, P Blier, C de Montign. Effects of the co-administration of mirtazapine and paroxetine on serotonergic neurotransmission in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 3. 2000-08-01. PMID:10793320. |
in the dorsal hippocampus, neither mirtazapine (5 mg/kg/day, s.c.) nor a paroxetine (10 mg/kg/day, s.c.) treatment altered the responsiveness of 5-ht(1a) receptors to microiontophoretically-applied 5-ht. |
2000-08-01 |
2023-08-12 |
rat |
| J J Hagan, G W Price, P Jeffrey, N J Deeks, T Stean, D Piper, M I Smith, N Upton, A D Medhurst, D N Middlemiss, G J Riley, P J Lovell, S M Bromidge, D R Thoma. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821781. |
5-ct-stimulated adenylyl cyclase activity in guinea-pig hippocampal membranes (pec(50) of 8.4+/-0.2) was inhibited by sb-269970-a (0.3 microm) with a pk(b) (8.3+/-0.1) in good agreement with its antagonist potency at the human cloned 5-ht(7(a)) receptor and its binding affinity at guinea-pig cortical membranes. |
2000-08-01 |
2023-08-12 |
human |
| J J Hagan, G W Price, P Jeffrey, N J Deeks, T Stean, D Piper, M I Smith, N Upton, A D Medhurst, D N Middlemiss, G J Riley, P J Lovell, S M Bromidge, D R Thoma. Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821781. |
5-ht(7) receptor mrna was highly expressed in human hypothalamus, amygdala, thalamus, hippocampus and testis. |
2000-08-01 |
2023-08-12 |
human |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. |
2000-08-01 |
2023-08-12 |
rat |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
here we determined whether the specific nitric oxide synthase (nos) inhibitor 7-nitroindazole (7-ni), the non-selective inhibitor of guanylate cyclase (gc) and nos, methylene blue (mb), the no-precursor l-arginine (l-arg), and the selective soluble gc inhibitor 1h-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (odq) affect extracellular levels of serotonin (5-ht), dopamine (da), 5-hydroxyindoleacetic acid (5-hiaa), and homovanillic acid (hva) in the rat ventral hippocampus by using microdialysis in freely moving animals. |
2000-08-01 |
2023-08-12 |
rat |
| G Wegener, V Volke, R Rosenber. Endogenous nitric oxide decreases hippocampal levels of serotonin and dopamine in vivo. British journal of pharmacology. vol 130. issue 3. 2000-08-01. PMID:10821785. |
retrodialysis of l-arg (2 mm) decreased the levels of 5-ht, da, 5-hiaa and hva in the hippocampus. |
2000-08-01 |
2023-08-12 |
rat |