| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R G Peñalva, C Flachskamm, S Zimmermann, W Wurst, F Holsboer, J M H M Reul, A C E Linthors. Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice. Neuroscience. vol 109. issue 2. 2002-04-12. PMID:11801362. |
forced swimming caused a rise in hippocampal serotonin followed by a further increase after the end of the stress paradigm in all genotypes. |
2002-04-12 |
2023-08-12 |
mouse |
| Eitan Gur, Eliyahu Dremencov, Louis D Van De Kar, Bernard Lerer, Michael E Newma. Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus. European journal of pharmacology. vol 436. issue 1-2. 2002-04-12. PMID:11834247. |
the effects of chronic administration of the mixed serotonin [5-hydroxytryptamine (5-ht)]/norepinephrine re-uptake inhibitor venlafaxine (5 mg/kg daily by osmotic minipump for 28 days) on the sensitivity of somatodendritic 5-ht(1a) autoreceptors on serotonergic neurons innervating the hypothalamus, and on 5-ht(1b) autoreceptors in both hypothalamus and hippocampus, were determined using in vivo microdialysis in freely moving rats. |
2002-04-12 |
2023-08-12 |
rat |
| Eitan Gur, Eliyahu Dremencov, Louis D Van De Kar, Bernard Lerer, Michael E Newma. Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus. European journal of pharmacology. vol 436. issue 1-2. 2002-04-12. PMID:11834247. |
venlafaxine induced a reduction in sensitivity of 5-ht(1b) autoreceptors in hypothalamus, but did not affect the sensitivity of 5-ht(1a) autoreceptors, or of 5-ht(1b) autoreceptors in hippocampus. |
2002-04-12 |
2023-08-12 |
rat |
| V Varga, A Sik, T F Freund, B Kocsi. GABA(B) receptors in the median raphe nucleus: distribution and role in the serotonergic control of hippocampal activity. Neuroscience. vol 109. issue 1. 2002-04-11. PMID:11784704. |
median raphe lesion, suppression of 5-ht neuronal activity by administration of gaba(a) receptor antagonist or by glutamate blockade or depletion produced long-lasting non-interrupted hippocampal theta in freely behaving rats independent of behavior and in rats anesthetized with urethane. |
2002-04-11 |
2023-08-12 |
rat |
| K Y Vinod, M N Subhas. Lamotrigine induced selective changes in 5-HT(1A) receptor mediated response in rat brain. Neurochemistry international. vol 40. issue 4. 2002-04-05. PMID:11792461. |
the density of 5-ht(1a) receptors was measured by radioligand binding assay using [(3)h]8-oh-dpat (0.05-0.8nm) in frontal cortex and hippocampus of rats treated orally with ltg (5mg/kg) for 7 days. |
2002-04-05 |
2023-08-12 |
rat |
| K Y Vinod, M N Subhas. Lamotrigine induced selective changes in 5-HT(1A) receptor mediated response in rat brain. Neurochemistry international. vol 40. issue 4. 2002-04-05. PMID:11792461. |
the oral administration of ltg significantly decreased the density of cortical (50%, p<0.001) but not hippocampal 5-ht(1a) receptors, without significant change in the affinity of [(3)h]8-oh-dpat to 5-ht(1a) receptor in these regions. |
2002-04-05 |
2023-08-12 |
rat |
| R J Thielen, D J Bare, W J McBride, L Lumeng, T-K L. Ethanol-stimulated serotonin release in the ventral hippocampus: an absence of rapid tolerance for the alcohol-preferring P rat and insensitivity in the alcohol-nonpreferring NP rat. Pharmacology, biochemistry, and behavior. vol 71. issue 1-2. 2002-04-05. PMID:11812514. |
ethanol-stimulated serotonin release in the ventral hippocampus: an absence of rapid tolerance for the alcohol-preferring p rat and insensitivity in the alcohol-nonpreferring np rat. |
2002-04-05 |
2023-08-12 |
rat |
| R J Thielen, D J Bare, W J McBride, L Lumeng, T-K L. Ethanol-stimulated serotonin release in the ventral hippocampus: an absence of rapid tolerance for the alcohol-preferring P rat and insensitivity in the alcohol-nonpreferring NP rat. Pharmacology, biochemistry, and behavior. vol 71. issue 1-2. 2002-04-05. PMID:11812514. |
this study examined the acute effects of intraperitoneal administration of ethanol on the extracellular levels of serotonin (5-ht) in the ventral hippocampus (vhip) of adult, male alcohol-preferring p and -nonpreferring np rats. |
2002-04-05 |
2023-08-12 |
rat |
| Anastasia Sfikakis, Zeta Papadopoulou-Daifotis, Nicholas Bika. Inverse relationship of hippocampal serotonin to avoidance behavior, serotonergic activation by emotional stress differentiated by estrous cycle and surgical stress. Behavioural brain research. vol 128. issue 1. 2002-04-04. PMID:11755688. |
inverse relationship of hippocampal serotonin to avoidance behavior, serotonergic activation by emotional stress differentiated by estrous cycle and surgical stress. |
2002-04-04 |
2023-08-12 |
rat |
| Anastasia Sfikakis, Zeta Papadopoulou-Daifotis, Nicholas Bika. Inverse relationship of hippocampal serotonin to avoidance behavior, serotonergic activation by emotional stress differentiated by estrous cycle and surgical stress. Behavioural brain research. vol 128. issue 1. 2002-04-04. PMID:11755688. |
after recording individual emotional reactivity (er) during handling for vaginal smear screening (vss), serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa), in the hypothalamus-preoptic area (hy-pa) and hippocampus were studied in two rat lines with different susceptibility to freund's adjuvant arthritis (faa), in relation to active avoidance behavior (ab), and under basal conditions in the faa susceptible strain, in relation to er, cycle stage and 20 h prior surgical stress. |
2002-04-04 |
2023-08-12 |
rat |
| Anastasia Sfikakis, Zeta Papadopoulou-Daifotis, Nicholas Bika. Inverse relationship of hippocampal serotonin to avoidance behavior, serotonergic activation by emotional stress differentiated by estrous cycle and surgical stress. Behavioural brain research. vol 128. issue 1. 2002-04-04. PMID:11755688. |
results suggest: negative association of hippocampal 5-ht to avoidance learning, a positive one to er, modulated by cycle stage, and a role of differentiated 5-ht in homeostasis of hpa system. |
2002-04-04 |
2023-08-12 |
rat |
| Hideki Miura, Hong Qiao, Tatsuro Oht. Attenuating effects of the isolated rearing condition on increased brain serotonin and dopamine turnover elicited by novelty stress. Brain research. vol 926. issue 1-2. 2002-04-04. PMID:11814401. |
da, dopac, and hva levels in the prefrontal cortex decreased, as did those of 5-ht in the prefrontal cortex and hippocampus. |
2002-04-04 |
2023-08-12 |
human |
| Hideki Miura, Hong Qiao, Tatsuro Oht. Attenuating effects of the isolated rearing condition on increased brain serotonin and dopamine turnover elicited by novelty stress. Brain research. vol 926. issue 1-2. 2002-04-04. PMID:11814401. |
the enhanced 5-ht turnover ratio in the prefrontal cortex, nucleus accumbens, and hippocampus of the group-reared group was attenuated in the isolated-reared group. |
2002-04-04 |
2023-08-12 |
human |
| Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza, Robert John Rodger. Effects of intra-hippocampal infusion of WAY-100635 on plus-maze behavior in mice. Influence of site of injection and prior test experience. Brain research. vol 927. issue 1. 2002-04-04. PMID:11814435. |
these findings suggest that postsynaptic 5-ht(1a) receptors in the ventral (but not dorsal) hippocampus play a significant role both in the mediation of plus-maze anxiety in mice and in experientially-induced alterations in responses to this test. |
2002-04-04 |
2023-08-12 |
mouse |
| Julie C Price, David E Kelley, Christopher M Ryan, Carolyn C Meltzer, Wayne C Drevets, Chester A Mathis, Sati Mazumdar, Charles F Reynold. Evidence of increased serotonin-1A receptor binding in type 2 diabetes: a positron emission tomography study. Brain research. vol 927. issue 1. 2002-04-04. PMID:11814436. |
significantly greater 5-ht(1a) receptor binding was detected in mesial temporal cortex, including hippocampus (p<0.05) for type 2 subjects (relative to controls). |
2002-04-04 |
2023-08-12 |
human |
| Luc Zimmer, Gweltas Mauger, Didier Le Bars, Gregory Bonmarchand, André Luxen, Jean-François Pujo. Effect of endogenous serotonin on the binding of the 5-hT1A PET ligand 18F-MPPF in the rat hippocampus: kinetic beta measurements combined with microdialysis. Journal of neurochemistry. vol 80. issue 2. 2002-04-04. PMID:11902118. |
effect of endogenous serotonin on the binding of the 5-ht1a pet ligand 18f-mppf in the rat hippocampus: kinetic beta measurements combined with microdialysis. |
2002-04-04 |
2023-08-12 |
human |
| Luc Zimmer, Gweltas Mauger, Didier Le Bars, Gregory Bonmarchand, André Luxen, Jean-François Pujo. Effect of endogenous serotonin on the binding of the 5-hT1A PET ligand 18F-MPPF in the rat hippocampus: kinetic beta measurements combined with microdialysis. Journal of neurochemistry. vol 80. issue 2. 2002-04-04. PMID:11902118. |
by using a combination of an original beta+-sensitive intracerebral probe and microdialysis, the effect of increased endogenous serotonin on specific binding of 18f-mppf [4-(2'-methoxyphenyl)-1-[2'-[n-(2"-pyridinyl)-p-fluorobenzamido]ethyl]piperazine] to the serotonin-1a (5-ht1a) receptors was investigated in the hippocampus of the anaesthetized rat. |
2002-04-04 |
2023-08-12 |
human |
| Luc Zimmer, Gweltas Mauger, Didier Le Bars, Gregory Bonmarchand, André Luxen, Jean-François Pujo. Effect of endogenous serotonin on the binding of the 5-hT1A PET ligand 18F-MPPF in the rat hippocampus: kinetic beta measurements combined with microdialysis. Journal of neurochemistry. vol 80. issue 2. 2002-04-04. PMID:11902118. |
the serotonin neuronal release was pharmacologically enhanced using fenfluramine at three different doses (1, 2 and 10 mg/kg intravenous) multiplying by 2-15 the extracellular serotonin in the hippocampus. |
2002-04-04 |
2023-08-12 |
human |
| Luc Zimmer, Gweltas Mauger, Didier Le Bars, Gregory Bonmarchand, André Luxen, Jean-François Pujo. Effect of endogenous serotonin on the binding of the 5-hT1A PET ligand 18F-MPPF in the rat hippocampus: kinetic beta measurements combined with microdialysis. Journal of neurochemistry. vol 80. issue 2. 2002-04-04. PMID:11902118. |
our results showed for the first time that 18f-mppf binding could be modulated by modifications of extracellular serotonin in the rat hippocampus. |
2002-04-04 |
2023-08-12 |
human |
| J Harro, M Tõnissaar, M Eller, A Kask, L Orelan. Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: effects on behavior and monoamine neurochemistry. Brain research. vol 899. issue 1-2. 2002-04-02. PMID:11311884. |
pca reduced 5-ht and 5-hiaa levels in the frontal cortex, hippocampus, and septum by approximately 20%. |
2002-04-02 |
2023-08-12 |
rat |