| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Evrard, I Malagié, A-M Laporte, C Boni, N Hanoun, A-C Trillat, I Seif, E De Maeyer, A Gardier, M Hamon, J Adrie. Altered regulation of the 5-HT system in the brain of MAO-A knock-out mice. The European journal of neuroscience. vol 15. issue 5. 2002-05-23. PMID:11906526. |
compared to paired wild-type mice, basal extracellular 5-ht levels were increased in ventral hippocampus (+202%), frontal cortex (+96%) and dorsal raphe nucleus (drn, +147%) of mao-a mutant mice. |
2002-05-23 |
2023-08-12 |
mouse |
| L A C Lucas, B A McMille. Differences in brain area concentrations of dopamine and serotonin in Myers' High Ethanol Preferring (mHEP) and outbred rats. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 3. 2002-05-23. PMID:11956951. |
the concentrations of 5-ht and da were examined by hplc in five brain areas (prefrontal cortex, hippocampus, nucleus accumbens, striatum and hypothalamus) of ethanol-näive rats and after the oral administration of 0.25 or 1.0 g ethanol/kg in the male and female mhep rat, the male wistar rat, and the female sprague-dawley rat. |
2002-05-23 |
2023-08-12 |
rat |
| Serge Gobaille, Carmen Schleef, Viviane Hechler, Sandrine Viry, Dominique Aunis, Michel Maitr. Gamma-hydroxybutyrate increases tryptophan availability and potentiates serotonin turnover in rat brain. Life sciences. vol 70. issue 18. 2002-05-23. PMID:12002803. |
ghb to rats induces an accumulation of tryptophan and 5-hiaa (5-hydroxyindole acetic acid) in the frontal cortex, striatum and hippocampus without causing significant change in the tissue serotonin content. |
2002-05-23 |
2023-08-12 |
rat |
| A K Halladay, E Kirschner, K Hesse, H Fisher, G C Wagne. Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release. Pharmacology & toxicology. vol 89. issue 5. 2002-05-22. PMID:11881977. |
while both ampt and deprenyl did not alter fenfluramine induced serotonin or 5-hydroxyindoleacetic acid (5-hiaa) depletion in any area, pcpa did partially reduce the serotonin depletion in the hippocampus and hypothalamus. |
2002-05-22 |
2023-08-12 |
Not clear |
| J P Courade, F Caussade, K Martin, D Besse, C Delchambre, N Hanoun, M Hamon, A Eschalier, A Cloare. Effects of acetaminophen on monoaminergic systems in the rat central nervous system. Naunyn-Schmiedeberg's archives of pharmacology. vol 364. issue 6. 2002-05-21. PMID:11770008. |
significant increases in serotonin (5-ht) levels were found in the posterior cortex, hypothalamus, striatum, hippocampus and brain stem, but not spinal cord, 45 min after per os administration of 200-400 mg/kg of acetaminophen. |
2002-05-21 |
2023-08-12 |
rat |
| Stacy L Donovan, Laura A Mamounas, Anne M Andrews, Mary E Blue, James S McCaslan. GAP-43 is critical for normal development of the serotonergic innervation in forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978831. |
we found a nearly complete failure of 5-ht immunoreactive axons to innervate the cortex and hippocampus in gap-43-null (gap43-/-) mice. |
2002-05-20 |
2023-08-12 |
mouse |
| Stacy L Donovan, Laura A Mamounas, Anne M Andrews, Mary E Blue, James S McCaslan. GAP-43 is critical for normal development of the serotonergic innervation in forebrain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978831. |
abnormal ingrowth of 5-ht axons was apparent on postnatal day 0 (p0); quantitative analysis of p7 brains revealed significant reductions in the density of 5-ht axons in the cortex and hippocampus of gap43-/- mice relative to wild-type (wt) controls. |
2002-05-20 |
2023-08-12 |
mouse |
| Alison C Shakesby, Roger Anwyl, Michael J Rowa. Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978839. |
fluoxetine and fenfluramine, agents that raise hippocampal extracellular 5-ht concentration, blocked the induction of ltp in nonstressed animals, thus mimicking the effect of stress. |
2002-05-20 |
2023-08-12 |
rat |
| R Weitzdoerfer, N Gerstl, H Hoeger, W Mosgoeller, W Dreher, E Engidawork, J Overgaard-Larsen, B Lube. Long-term sequelae of perinatal asphyxia in the aging rat. Cellular and molecular life sciences : CMLS. vol 59. issue 3. 2002-05-16. PMID:11964129. |
increased serotonin transporter (sert) immunoreactivity in the ca2 region of the hippocampus and a significant difference in the escape latency, when the platform of the mwm was moved to a new location, were observed in asphyxiated rats. |
2002-05-16 |
2023-08-12 |
human |
| M Bauer, A Heinz, P C Whybro. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain. Molecular psychiatry. vol 7. issue 2. 2002-05-14. PMID:11840307. |
in the majority of studies, the effects of thyroid hormone administration in animals with experimentally-induced hypothyroid states include an increase in cortical 5-ht concentrations and a desensitization of autoinhibitory 5-ht1a receptors in the raphe area, resulting in disinhibition of cortical and hippocampal 5-ht release. |
2002-05-14 |
2023-08-12 |
Not clear |
| Taneli Heikkinen, Jukka Puoliväli, Li Liu, Anna Rissanen, Heikki Tanil. Effects of ovariectomy and estrogen treatment on learning and hippocampal neurotransmitters in mice. Hormones and behavior. vol 41. issue 1. 2002-05-01. PMID:11863380. |
furthermore, the effects of estrogen treatment on the levels of hippocampal 5-ht and its metabolite 5-hiaa were different in sham-operated than in ovx mice. |
2002-05-01 |
2023-08-12 |
mouse |
| R M Torack, J W Miller, K A Rot. Deafferentation-induced abnormal neurofilament phosphorylation in red nucleus neurones. Neuropathology and applied neurobiology. vol 27. issue 6. 2002-05-01. PMID:11903927. |
we previously developed a rodent model of hippocampal deafferentation involving bilateral destructive lesions of the ventrotegmental area (vta), septum of the medial forebrain and entorhinal cortex combined with pharmacological inhibition of serotonin 5-ht2 and dopamine d1 receptors. |
2002-05-01 |
2023-08-12 |
human |
| Naoyuki Hironaka, Takeshi Yagi, Hiroaki Nik. Light-potentiation of acoustic startle response (ASR) and monoamine efflux related to fearfulness in Fyn-deficient mice. Brain research. Molecular brain research. vol 98. issue 1-2. 2002-04-29. PMID:11834300. |
along with these behavioral findings, the homozygous fyn-deficient mice showed an increase in extracellular serotonin (5-ht) and dopamine (da) in the prefrontal cortex and 5-ht in the hippocampus when they were exposed to bright light, while heterozygous and wild-type mice did not show such changes. |
2002-04-29 |
2023-08-12 |
mouse |
| Annis O Mechan, Blanca Esteban, Esther O'Shea, J Martin Elliott, M Isabel Colado, A Richard Gree. The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats. British journal of pharmacology. vol 135. issue 1. 2002-04-26. PMID:11786492. |
the uptake inhibitor fluoxetine (10 mg kg(-1)) markedly attenuated the mdma-induced increase in hippocampal extracellular 5-ht, also without altering hyperthermia. |
2002-04-26 |
2023-08-12 |
rat |
| L V Devoĭno, E L Al'perina, E K Podgornaia, O V Poliakov, G V Idova, R Iu Il'iucheno. [Distribution of serotonin and its metabolites in the brain structures and immunosuppression in submissive mice]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 88. issue 1. 2002-04-25. PMID:11868254. |
the development of submissive behaviour in c57bl/6j mice in the sensory contact model was associated with an increase in the content of serotonin (5-ht) in the amygdala, hippocampus, dopaminergic nuclei a11, a10, a9, as well as in the caudate nucleus and hypothalamus after 10 and 20 days of confrontations compared to the controls. |
2002-04-25 |
2023-08-12 |
mouse |
| L A Dawson, J Galandak, S Djal. Attenuation of ischemic efflux of endogenous amino acids by the novel 5-HT(1A)/5-HT(2) receptor ligand adatanserin. Neurochemistry international. vol 40. issue 3. 2002-04-23. PMID:11741003. |
using sodium azide (nan3)-induced anoxia plus aglycaemia as a model of chemically-induced ischemia in the hippocampal slice, we have evaluated the effects of the novel 5-ht(1a) partial agonist/5-ht(2) receptor antagonist adatanserin and the 5-ht(1a) receptor agonist bayx3702 on the efflux of endogenous glutamate, aspartate and gaba. |
2002-04-23 |
2023-08-12 |
Not clear |
| Kaoru Fujino, Takashi Yoshitake, Osamu Inoue, Nobuhiro Ibii, Jan Kehr, Junichi Ishida, Hitoshi Nohta, Masatoshi Yamaguch. Increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. Neuroscience letters. vol 320. issue 1-2. 2002-04-18. PMID:11849771. |
increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. |
2002-04-18 |
2023-08-12 |
mouse |
| Kaoru Fujino, Takashi Yoshitake, Osamu Inoue, Nobuhiro Ibii, Jan Kehr, Junichi Ishida, Hitoshi Nohta, Masatoshi Yamaguch. Increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. Neuroscience letters. vol 320. issue 1-2. 2002-04-18. PMID:11849771. |
the basal levels of 5-ht in 3 min microdialysates from the ventral hippocampus and frontal cortex were 0.68+/-0.21 and 0.75+/-0.28 fmol/6 microl (n=24), respectively. |
2002-04-18 |
2023-08-12 |
mouse |
| R G Peñalva, C Flachskamm, S Zimmermann, W Wurst, F Holsboer, J M H M Reul, A C E Linthors. Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice. Neuroscience. vol 109. issue 2. 2002-04-12. PMID:11801362. |
hippocampal dialysates were used to measure extracellular levels of serotonin and its metabolite 5-hydroxyindoleacetic acid, and free corticosterone levels to monitor the status of the hypothalamic-pituitary-adrenocortical axis. |
2002-04-12 |
2023-08-12 |
mouse |
| R G Peñalva, C Flachskamm, S Zimmermann, W Wurst, F Holsboer, J M H M Reul, A C E Linthors. Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice. Neuroscience. vol 109. issue 2. 2002-04-12. PMID:11801362. |
homozygous crh-r1-deficient mice showed enhanced hippocampal levels of 5-hydroxyindoleacetic acid but not of serotonin during the light and the dark phase of the diurnal cycle, which may point to an enhanced synthesis of serotonin in the raphe-hippocampal system. |
2002-04-12 |
2023-08-12 |
mouse |