| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Kehoe, K Mallinson, J Bronzino, C M McCormic. Effects of prenatal protein malnutrition and neonatal stress on CNS responsiveness. Brain research. Developmental brain research. vol 132. issue 1. 2002-03-05. PMID:11744104. |
prenatal protein malnutrition also resulted in a significant elevation in serotonin in both brain areas, increased 5hiaa in the hypothalamus, and decreased dopamine in the hippocampus. |
2002-03-05 |
2023-08-12 |
rat |
| H R Lam, P Plenge, O S Jørgense. Effects of white spirits on rat brain 5-HT receptor functions and synaptic remodeling. Neurotoxicology and teratology. vol 23. issue 6. 2002-03-01. PMID:11792528. |
this study investigates the effects of two types of white spirit on 5-hydroxytryptamine (5-ht) transporters (5-htt), 5-ht(2a) and 5-ht(4) receptor expression in forebrain, and on neural cell adhesion molecule (ncam) and 25-kda synaptosomal associated protein (snap-25) concentrations when applied as indices for synaptic remodeling in forebrain, hippocampus, and entorhinal cortex. |
2002-03-01 |
2023-08-12 |
rat |
| M T Vilaró, T Doménech, J M Palacios, G Mengo. Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxy terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variants. Neuropharmacology. vol 42. issue 1. 2002-02-20. PMID:11750916. |
we have cloned a novel c-terminal splice variant of serotonin 5-ht4 receptors from human hippocampus. |
2002-02-20 |
2023-08-12 |
human |
| D Gomez-Merino, F Béquet, M Berthelot, S Riverain, M Chennaoui, C Y Guezenne. Evidence that the branched-chain amino acid L-valine prevents exercise-induced release of 5-HT in rat hippocampus. International journal of sports medicine. vol 22. issue 5. 2002-02-07. PMID:11510866. |
evidence that the branched-chain amino acid l-valine prevents exercise-induced release of 5-ht in rat hippocampus. |
2002-02-07 |
2023-08-12 |
human |
| D Gomez-Merino, F Béquet, M Berthelot, S Riverain, M Chennaoui, C Y Guezenne. Evidence that the branched-chain amino acid L-valine prevents exercise-induced release of 5-HT in rat hippocampus. International journal of sports medicine. vol 22. issue 5. 2002-02-07. PMID:11510866. |
the purpose of this study was to assess, using a combined venous catheterization and in vivo microdialysis method, the effect of pre-exercise l-valine administration on 5-hydroxytryptamine (5-ht) metabolism in the ventral hippocampus of rats submitted to an acute intensive treadmill running (120 min at 25 m x min(-1) followed by 150 min of recovery). |
2002-02-07 |
2023-08-12 |
human |
| D Gomez-Merino, F Béquet, M Berthelot, S Riverain, M Chennaoui, C Y Guezenne. Evidence that the branched-chain amino acid L-valine prevents exercise-induced release of 5-HT in rat hippocampus. International journal of sports medicine. vol 22. issue 5. 2002-02-07. PMID:11510866. |
the data clearly demonstrate that exercise induces 5-ht release in the rat hippocampus: in control group, hippocampal 5-ht levels increase from 123.7 +/- 6.4% at the end of exercise to 133.9 +/- 6.4% after 60 min of recovery. |
2002-02-07 |
2023-08-12 |
human |
| D Gomez-Merino, F Béquet, M Berthelot, S Riverain, M Chennaoui, C Y Guezenne. Evidence that the branched-chain amino acid L-valine prevents exercise-induced release of 5-HT in rat hippocampus. International journal of sports medicine. vol 22. issue 5. 2002-02-07. PMID:11510866. |
the present study evidences that an acute intensive exercise stimulates 5-ht metabolism in the rat hippocampus, and that a pre-exercise administration of l-valine prevents, via a limiting effect on 5-ht synthesis, exercise-induced 5-ht release. |
2002-02-07 |
2023-08-12 |
human |
| R S Duman, S Nakagawa, J Malber. Regulation of adult neurogenesis by antidepressant treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 6. 2002-01-28. PMID:11750177. |
recent studies from our laboratory and others demonstrate that chronic administration of an antidepressant, including either a 5-ht or norepinephrine selective reuptake inhibitor, up-regulates neurogenesis in adult rodent hippocampus. |
2002-01-28 |
2023-08-12 |
Not clear |
| S T Szabo, P Blie. Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 6. 2002-01-28. PMID:11750178. |
effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. |
2002-01-28 |
2023-08-12 |
rat |
| S T Szabo, P Blie. Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 6. 2002-01-28. PMID:11750178. |
given that norepinephrine (ne) and serotonin (5-ht) neurons are implicated in the mechanisms of action of antidepressant drugs and both project to the hippocampus, the impact of acute and long-term administration of the selective ne inhibitor reboxetine was assessed on ca(3) pyramidal neuron firing in this postsynaptic structure. |
2002-01-28 |
2023-08-12 |
rat |
| S T Szabo, P Blie. Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 6. 2002-01-28. PMID:11750178. |
in controls and reboxetine-treated rats, 1 and 5 hz stimulations of the afferent 5-ht bundle to the hippocampus, which allows determination of terminal 5-ht(1b) autoreceptor sensitivity, produced similar frequency-dependent decreases in pyramidal neuron firing in both groups. |
2002-01-28 |
2023-08-12 |
rat |
| N K Popova, M A Gilinsky, T G Amstislavskaya, E A Morosova, I Seif, E De Maeye. Regional serotonin metabolism in the brain of transgenic mice lacking monoamine oxidase A. Journal of neuroscience research. vol 66. issue 3. 2002-01-25. PMID:11746359. |
the effect of a lack of the gene encoding monoamine oxidase a (mao a) in transgenic tg8 mice on the activity of tryptophan hydroxylase (tph), the rate-limiting enzyme in serotonin (5-ht) biosynthesis, and on the levels of 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) in the midbrain, hypothalamus, hippocampus, striatum, amygdala, and frontal cortex was studied. |
2002-01-25 |
2023-08-12 |
mouse |
| A J Montgomery, C J Bench, A H Young, A Hammers, R N Gunn, Z Bhagwagar, P M Grasb. PET measurement of the influence of corticosteroids on serotonin-1A receptor number. Biological psychiatry. vol 50. issue 9. 2002-01-24. PMID:11704073. |
the modulatory effect of corticosteroids on 5-ht(1a) receptor number and function has been repeatedly demonstrated in preclinical studies suggesting that raised corticosteroid levels decrease 5-ht(1a) receptor number and function in the hippocampus. |
2002-01-24 |
2023-08-12 |
Not clear |
| C Stenfors, S B Ros. Hypothermia reduces the rate of dissociation of specific ligands from dopamine-D2 and 5-hydroxytryptamine1A receptors in the mouse brain in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 364. issue 5. 2002-01-15. PMID:11692232. |
in accordance with this view, increased synaptic 5-ht evoked by the 5-ht releasing agent p-chloroamphetamine enhanced the disappearance of [3h]robalzotan from hippocampus and frontal cortex. |
2002-01-15 |
2023-08-12 |
mouse |
| M Shirane, K Nakamur. Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597608. |
aniracetam, a cognition enhancer, has been recently found to preferentially increase extracellular levels of dopamine (da) and serotonin (5-ht) in the prefrontal cortex (pfc), basolateral amygdala and dorsal hippocampus of the mesocorticolimbic system in stroke-prone spontaneously hypertensive rats. |
2002-01-14 |
2023-08-12 |
rat |
| M Banasr, M Hery, J M Brezun, A Daszut. Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus. The European journal of neuroscience. vol 14. issue 9. 2002-01-11. PMID:11722603. |
as 5-ht and oestrogen are involved in mood disorders, our data suggest that the positive regulation of cell proliferation and neuroplasticity by these two factors may contribute to restore hippocampal connectivity in depressive patients. |
2002-01-11 |
2023-08-12 |
rat |
| H Tsukada, T Kakiuchi, S Nishiyama, H Ohba, N Harad. Effects of aging on 5-HT(1A) receptors and their functional response to 5-HT(1a) agonist in the living brain: PET study with [carbonyl-(11)C]WAY-100635 in conscious monkeys. Synapse (New York, N.Y.). vol 42. issue 4. 2002-01-10. PMID:11746722. |
in the hippocampus, although 5-ht(1a) receptor binding indicated no significant age-related changes, it showed an inverse correlation with individual cortisol levels in plasma. |
2002-01-10 |
2023-08-12 |
monkey |
| L A Dawson, H Q Nguyen, P L. The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 5. 2002-01-03. PMID:11682249. |
the 5-ht(6) receptor antagonist sb-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. |
2002-01-03 |
2023-08-12 |
rat |
| L A Dawson, H Q Nguyen, P L. The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 5. 2002-01-03. PMID:11682249. |
sb-271046 produced no change in basal levels of dopamine (da), norepinephrine (ne) or 5-ht in the striatum, frontal cortex, dorsal hippocampus or nucleus accumbens. |
2002-01-03 |
2023-08-12 |
rat |
| F Béquet, D Gomez-Merino, M Berthelot, C Y Guezenne. Exercise-induced changes in brain glucose and serotonin revealed by microdialysis in rat hippocampus: effect of glucose supplementation. Acta physiologica Scandinavica. vol 173. issue 2. 2002-01-02. PMID:11683680. |
exercise-induced changes in brain glucose and serotonin revealed by microdialysis in rat hippocampus: effect of glucose supplementation. |
2002-01-02 |
2023-08-12 |
rat |