| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Mlinar, A M Pugliese, R Corradett. Selective inhibition of local excitatory synaptic transmission by serotonin through an unconventional receptor in the CA1 region of rat hippocampus. The Journal of physiology. vol 534. issue Pt 1. 2001-09-13. PMID:11432998. |
selective inhibition of local excitatory synaptic transmission by serotonin through an unconventional receptor in the ca1 region of rat hippocampus. |
2001-09-13 |
2023-08-12 |
rat |
| B Mlinar, A M Pugliese, R Corradett. Selective inhibition of local excitatory synaptic transmission by serotonin through an unconventional receptor in the CA1 region of rat hippocampus. The Journal of physiology. vol 534. issue Pt 1. 2001-09-13. PMID:11432998. |
the modulation of synaptic transmission by serotonin (5-ht) was studied using whole-cell voltage-clamp and sharp-electrode current-clamp recordings from ca1 pyramidal neurones in transverse rat hippocampal slices in vitro. |
2001-09-13 |
2023-08-12 |
rat |
| B Mlinar, A M Pugliese, R Corradett. Selective inhibition of local excitatory synaptic transmission by serotonin through an unconventional receptor in the CA1 region of rat hippocampus. The Journal of physiology. vol 534. issue Pt 1. 2001-09-13. PMID:11432998. |
this may represent an important physiological action of 5-ht in the hippocampus, since it occurs over a lower concentration range than the 5-ht effects reported so far. |
2001-09-13 |
2023-08-12 |
rat |
| D A Knobelman, R Hen, I Luck. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504805. |
the regulation of extracellular levels of 5-hydroxytryptamine (serotonin) (5-ht) in the striatum and ventral hippocampus was studied using in vivo microdialysis in awake, unrestrained wild-type 5-ht(1a) and 5-ht(1b) receptor knockout mice. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, I Luck. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504805. |
systemic administration of the selective serotonin reuptake inhibitor fluoxetine evoked a significant dose-dependent increase in extracellular 5-ht in both the striatum and hippocampus at both 2.5 mg/kg (i.p.) |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, I Luck. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504805. |
in 5-ht(1a) receptor knockout mice, the response to 2.5 mg/kg fluoxetine was significantly augmented in the striatum but not the hippocampus, whereas the response to 20 mg/kg fluoxetine was significantly greater in both brain regions. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, I Luck. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504805. |
in 5-ht(1b) receptor knockout mice, the increase of extracellular 5-ht was augmented in the hippocampus but not the striatum at both doses of fluoxetine. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, I Luck. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504805. |
the 5-ht(1a) autoreceptor plays a larger role in regulating 5-ht release in the striatum and possibly other brain regions innervated by the dorsal raphe nucleus, whereas the role of the 5-ht(1b) receptor is relatively greater in the hippocampus and possibly other brain regions innervated by the median raphe nucleus. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, J A Blendy, I Luck. Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504806. |
plasticity in serotonergic transmission in serotonin or 5-hydroxytryptamine (5-ht) receptor mutants was examined by measuring the regulation of extracellular 5-ht levels in the striatum and ventral hippocampus of 5-ht(1a) and 5-ht(1b) receptor knockout mice using in vivo microdialysis. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, J A Blendy, I Luck. Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504806. |
5-ht(1a) receptor knockout mice demonstrated a significantly greater response to cp 94,253 in the striatum, but not the ventral hippocampus, suggesting the development of enhanced sensitivity of striatal 5-ht(1b) receptors. |
2001-09-13 |
2023-08-12 |
mouse |
| D A Knobelman, R Hen, J A Blendy, I Luck. Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse. The Journal of pharmacology and experimental therapeutics. vol 298. issue 3. 2001-09-13. PMID:11504806. |
in 5-ht(1b) receptor knockout mice, r-8-oh-dpat evoked a significantly diminished response in the ventral hippocampus, but not the striatum, suggesting the potential desensitization of 5-ht(1a) receptors in the median raphe nucleus. |
2001-09-13 |
2023-08-12 |
mouse |
| A V Sergutina, L M Gershtei. Neurochemical characteristics of the effects of delta sleep-inducing peptide in Wistar rats with hyperactivity of the dopaminergic system. Bulletin of experimental biology and medicine. vol 130. issue 11. 2001-09-06. PMID:11182819. |
quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and glutamate dehydrogenase activity in the hippocampus of stress-resistant wistar rats chronically treated with l-dopa. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
we monitored the effects of sucrose and starch on concentrations of extracellular 5ht, its metabolite 5-hydroxyindoleacetic acid (5hiaa), gamma-aminobutyric acid (gaba) and dopamine in the hippocampus, using in vivo microdialysis. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
the major finding was that baseline levels of extracellular hippocampal 5ht in rats with ad libitum access to food supplemented with sucrose were significantly higher compared with the starch control group. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
we then verified that sucrose supplementation affected the potency of s(+)fenfluramine to increase hippocampal 5ht levels. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
in both groups of rats, acute intraperitoneal injection (1 mg/kg) of this anorectic drug induced a response curve of the extracellular hippocampal 5ht levels, with a shape that corresponded with earlier data for different brain areas often using up to 10-fold higher doses of s(+)fenfluramine. |
2001-09-06 |
2023-08-12 |
rat |
| I Smolders, J V Loo, S Sarre, G Ebinger, Y Michott. Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat. The British journal of nutrition. vol 86. issue 2. 2001-09-06. PMID:11502227. |
a practical implication of the present findings is that dietary sucrose may bias the results of studies investigating brain serotoninergic mechanisms and the effects of (anorectic) drugs interacting with 5ht systems in the hippocampus. |
2001-09-06 |
2023-08-12 |
rat |
| A R Ase, T A Reader, R Hen, M Riad, L Descarrie. Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. Journal of neurochemistry. vol 78. issue 3. 2001-08-30. PMID:11483665. |
(iv) the 5-ht hyperinnervation in the amygdalo-hippocampal nucleus and ventral hippocampus of 5-ht1b kos could play a role in their increased aggressiveness, and might also explain their better performance in some cognitive tests. |
2001-08-30 |
2023-08-12 |
mouse |
| Y Kawata, M Okada, T Murakami, A Kamata, G Zhu, S Kanek. Pharmacological discrimination between effects of carbamazepine on hippocampal basal, Ca(2+)- and K(+)-evoked serotonin release. British journal of pharmacology. vol 133. issue 4. 2001-08-23. PMID:11399673. |
pharmacological discrimination between effects of carbamazepine on hippocampal basal, ca(2+)- and k(+)-evoked serotonin release. |
2001-08-23 |
2023-08-12 |
rat |