| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Motohiro Okada, Gang Zhu, Shukuko Yoshida, Hiroto Iwasa, Sunao Kanek. [Mechanisms of interaction between adenosine receptor subtypes on hippocampal serotonin release]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 22. issue 2. 2002-07-30. PMID:12050854. |
[mechanisms of interaction between adenosine receptor subtypes on hippocampal serotonin release]. |
2002-07-30 |
2023-08-12 |
rat |
| Motohiro Okada, Gang Zhu, Shukuko Yoshida, Hiroto Iwasa, Sunao Kanek. [Mechanisms of interaction between adenosine receptor subtypes on hippocampal serotonin release]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 22. issue 2. 2002-07-30. PMID:12050854. |
therefore pka activity plays an important role in the interaction between a1r and a2r on hippocampal 5-ht release. |
2002-07-30 |
2023-08-12 |
rat |
| E Nowakowska, A Chodera, K Kus, P Nowak, R Szkilni. Reversal of stress-induced memory changes by moclobemide: the role of neurotransmitters. Polish journal of pharmacology. vol 53. issue 3. 2002-07-19. PMID:11785923. |
in this study, we investigated the effects of chronic stress procedure and moclobemide in rats, and the influence of chronic stress on the levels of monoamines: noradrenaline (ne), dopamine (da) and serotonin (5-ht) in the rat hippocampus [as well as their metabolites: dihydroxyphenylacetic acid (dopac) and 5-hydroxyindoleacetic acid (5-hiaa)]. |
2002-07-19 |
2023-08-12 |
rat |
| G J Blatt, C M Fitzgerald, J T Guptill, A B Booker, T L Kemper, M L Bauma. Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study. Journal of autism and developmental disorders. vol 31. issue 6. 2002-07-16. PMID:11814263. |
based on these observations in the hippocampus, a series of quantitative receptor autoradiographic studies were undertaken to determine the density and distribution of eight types of neurotransmitter receptors from four neurotransmitter systems (gabaergic, serotoninergic [5-ht], cholinergic, and glutamatergic). |
2002-07-16 |
2023-08-12 |
Not clear |
| J Read, B D Perry, A Moskowitz, J Connoll. The contribution of early traumatic events to schizophrenia in some patients: a traumagenic neurodevelopmental model. Psychiatry. vol 64. issue 4. 2002-07-16. PMID:11822210. |
a traumagenic neurodevelopmental (tn) model of schizophrenia is presented, documenting the similarities between the effects of traumatic events on the developing brain and the biological abnormalities found in persons diagnosed with schizophrenia, including overreactivity of the hypothalamic-pituitary-adrenal (hpa) axis; dopamine, norepinephrine, and serotonin abnormalities; and structural changes to the brain such as hippocampal damage, cerebral atrophy, ventricular enlargement, and reversed cerebral asymmetry. |
2002-07-16 |
2023-08-12 |
Not clear |
| Anja Birthelmer, Esther Dommes, Hélène Jeltsch, Jean-Christophe Cassel, Rolf Jackisc. Septal grafts and evoked acetylcholine release in the rat hippocampus after 192 IgG-saporin lesions. Neuroreport. vol 13. issue 7. 2002-07-16. PMID:12004202. |
between 6 and 10 months later, we assessed baseline and electrically-evoked release of tritium in hippocampal slices preloaded with [(3)h]choline, and the uptake of [(3)h]choline, [(3)h]noradrenaline and [(3)h]serotonin by hippocampal synaptosomes. |
2002-07-16 |
2023-08-12 |
rat |
| Anja Birthelmer, Esther Dommes, Hélène Jeltsch, Jean-Christophe Cassel, Rolf Jackisc. Septal grafts and evoked acetylcholine release in the rat hippocampus after 192 IgG-saporin lesions. Neuroreport. vol 13. issue 7. 2002-07-16. PMID:12004202. |
the lesions reduced the accumulation of [(3)h]choline by approximately 40%, the evoked release of [(3)h]acetylcholine by approximately 90%, and the uptake of [(3)h]choline by synaptosomes by 90% in the dorsal hippocampus, but increased the relative baseline release of [(3)h]choline by +43%, and the synaptosomal uptake of [(3)h]noradrenaline (66%) and [(3)h]serotonin (58%) in the ventral hippocampus. |
2002-07-16 |
2023-08-12 |
rat |
| Alex M Gra. The effect of fluvoxamine and sertraline on the opioid withdrawal syndrome: a combined in vivo cerebral microdialysis and behavioural study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 3. 2002-07-16. PMID:12007676. |
a microdialysis study was undertaken to determine the effect of acute and sub-chronic administration of the selective serotonin reuptake inhibitor, fluvoxamine, and the acute effect of the selective serotonin reuptake inhibitor sertraline, on the naloxone precipitated opioid withdrawal induced increase in hippocampal noradrenaline levels. |
2002-07-16 |
2023-08-12 |
rat |
| Pia Bartholomä, Nina Erlandsson, Katrin Kaufmann, Oliver G Rössler, Bernd Baumann, Thomas Wirth, Klaus M Giehl, Gerald Thie. Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation. Biochemical pharmacology. vol 63. issue 8. 2002-07-15. PMID:11996893. |
the tricyclic antidepressants (tca) amitriptyline and desipramine and the serotonin reuptake inhibitor fluoxetine induce, at microm concentrations, cell death in ht22 immortalized hippocampal neurons and pc12 pheochromocytoma cells. |
2002-07-15 |
2023-08-12 |
Not clear |
| Jennifer C Roberts, Charlie Reavill, Simon Z East, Paul J Harrison, Sara Patel, Carol Routledge, Ronald A Lesli. The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585. Brain research. vol 934. issue 1. 2002-07-12. PMID:11937069. |
the 5-ht(6) receptor ligand binding seen here in the striatum, accumbens, olfactory tubercle, islands of calleja, cerebral cortex and hippocampus are in concordance with previous immunohistochemical studies, and suggest a possible involvement of 5-ht(6) receptors in locomotor control, cognition, memory, and control of affect. |
2002-07-12 |
2023-08-12 |
rat |
| Esther M Chapin, Samir Haj-Dahmane, Gonzalo Torres, Rodrigo Andrad. The 5-HT(4) receptor-induced depolarization in rat hippocampal neurons is mediated by cAMP but is independent of I(h). Neuroscience letters. vol 324. issue 1. 2002-07-12. PMID:11983280. |
the 5-ht(4) receptor-induced depolarization in rat hippocampal neurons is mediated by camp but is independent of i(h). |
2002-07-12 |
2023-08-12 |
rat |
| Esther M Chapin, Samir Haj-Dahmane, Gonzalo Torres, Rodrigo Andrad. The 5-HT(4) receptor-induced depolarization in rat hippocampal neurons is mediated by cAMP but is independent of I(h). Neuroscience letters. vol 324. issue 1. 2002-07-12. PMID:11983280. |
intracellular recordings were used to examine the mechanisms underlying the 5-hydroxytryptamine (5-ht)4 receptor-mediated depolarization seen in ca1 region pyramidal cells in in vitro hippocampal brain slices. |
2002-07-12 |
2023-08-12 |
rat |
| Pascal Bonaventure, Diane Nepomuceno, Annette Kwok, Wenying Chai, Xavier Langlois, Rene Hen, Kimberly Stark, Nicholas Carruthers, Timothy W Lovenber. Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice. The Journal of pharmacology and experimental therapeutics. vol 302. issue 1. 2002-07-12. PMID:12065723. |
in contrast to the low densities of [(3)h]5-ct binding sites, high-to-moderate densities of [(3)h]8-oh-dpat binding sites (10 nm) were found throughout the brain of 5-ht(1a) and 5-ht(1a/1b) knockout mice (olfactory system, septum, thalamus, hypothalamus, amygdala, ca3 field of the hippocampus, cortical mantle, and central gray). |
2002-07-12 |
2023-08-12 |
mouse |
| M Jessa, P Krzaścik, W Kostowsk. Neonatal treatment with 5,7-dihydroxytryptamine induces decrease in alcohol drinking in adult animals. Polish journal of pharmacology. vol 53. issue 2. 2002-07-01. PMID:11787949. |
5,7-dht induced a marked and permanent decrease in brain 5-ht content, measured in the prefrontal cortex, hippocampus and striatum, but did not modify noradrenaline content in these structures. |
2002-07-01 |
2023-08-12 |
rat |
| Azair Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Robert John Rodger. Anxiolytic-like effect of way-100635 microinfusions into the median (but not dorsal) raphe nucleus in mice exposed to the plus-maze: influence of prior test experience. Brain research. vol 928. issue 1-2. 2002-05-23. PMID:11844471. |
studies in several laboratories have confirmed the anxiolytic potential of a wide range of 5-ht(1a) receptor antagonists in rats and mice, with recent evidence pointing to a postsynaptic site of action in the ventral hippocampus. |
2002-05-23 |
2023-08-12 |
mouse |
| Azair Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Robert John Rodger. Anxiolytic-like effect of way-100635 microinfusions into the median (but not dorsal) raphe nucleus in mice exposed to the plus-maze: influence of prior test experience. Brain research. vol 928. issue 1-2. 2002-05-23. PMID:11844471. |
hippocampus and amygdala), where stimulation of postsynaptic 5-ht(1a) receptors enhances anxiety-like responses. |
2002-05-23 |
2023-08-12 |
mouse |
| Inmaculada Bellido, Aurelio Gomez-Luque, Antonio Plaza, Francisca Rius, Pablo Ortiz, Felipe Sanchez de la Cuest. S-adenosyl-L-methionine prevents 5-HT(1A) receptors up-regulation induced by acute imipramine in the frontal cortex of the rat. Neuroscience letters. vol 321. issue 1-2. 2002-05-23. PMID:11872268. |
all the chronic treatments showed antidepressant effects and up-regulated the hippocampus 5-ht(1a) receptors. |
2002-05-23 |
2023-08-12 |
rat |
| L Matuszewich, M E Filon, D A Finn, B K Yamamot. Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine. Neuroscience. vol 110. issue 1. 2002-05-23. PMID:11882371. |
seven days after treatment, in vivo microdialysis was used to assess extracellular dopamine and serotonin in the dorsal hippocampus and prefrontal cortex during 1 h of immobilization stress. |
2002-05-23 |
2023-08-12 |
rat |
| L Matuszewich, M E Filon, D A Finn, B K Yamamot. Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine. Neuroscience. vol 110. issue 1. 2002-05-23. PMID:11882371. |
in saline treated control rats, serotonin in the hippocampus and serotonin and dopamine in the prefrontal cortex were increased during immobilization stress. |
2002-05-23 |
2023-08-12 |
rat |
| L Matuszewich, M E Filon, D A Finn, B K Yamamot. Altered forebrain neurotransmitter responses to immobilization stress following 3,4-methylenedioxymethamphetamine. Neuroscience. vol 110. issue 1. 2002-05-23. PMID:11882371. |
in the drug pretreated rats, basal serotonin levels in the hippocampus, but not the prefrontal cortex, were lower compared to saline pretreated controls. |
2002-05-23 |
2023-08-12 |
rat |