| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lotte De Groote, Berend Olivier, Herman G M Westenber. The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice. European journal of pharmacology. vol 439. issue 1-3. 2002-08-08. PMID:11937097. |
basal 5-ht levels in the hippocampus were not different between the two genotypes. |
2002-08-08 |
2023-08-12 |
mouse |
| Lotte De Groote, Berend Olivier, Herman G M Westenber. The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice. European journal of pharmacology. vol 439. issue 1-3. 2002-08-08. PMID:11937097. |
the functional absence of 5-ht(1b) receptors was examined in the knockout mice by local infusion of the 5-ht(1b) receptor agonist, 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5h-pyrrolo[3,2-b]pyridin-5-one (cp93129) into the hippocampus. |
2002-08-08 |
2023-08-12 |
mouse |
| Lotte De Groote, Berend Olivier, Herman G M Westenber. The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice. European journal of pharmacology. vol 439. issue 1-3. 2002-08-08. PMID:11937097. |
therefore, the selective 5-ht reuptake inhibitor, fluvoxamine, was applied locally into the hippocampus to investigate the role of the terminal 5-ht(1b) autoreceptors. |
2002-08-08 |
2023-08-12 |
mouse |
| Lotte De Groote, Berend Olivier, Herman G M Westenber. The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice. European journal of pharmacology. vol 439. issue 1-3. 2002-08-08. PMID:11937097. |
in conclusion, the differences in hippocampal 5-ht output between wildtype and 5-ht(1b) knockout mice after local or systemic administration of selective 5-ht reuptake inhibitors show that 5-ht(1b) autoreceptors play a significant role in the inhibition of 5-ht release at serotonergic nerve terminals. |
2002-08-08 |
2023-08-12 |
mouse |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
neuronal activity in the hippocampus and the nucleus accumbens (nac) depend on serotonergic (5-ht) transmission. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
here we describe for the first time a cocaine-induced increase in 5-ht concentration in the hippocampus and the nac parallel to behavioral activation. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
in addition, pretreatment with the 5-ht(1a)-receptor antagonist way 100635 blocked the behavioral activation after cocaine while potentiating the 5-ht increase in the hippocampus and the nac. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
in vivo microdialysis was used in behaving rats to measure extracellular concentration of 5-ht in the hippocampus and the nac. |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
cocaine, at a dose that activates behavior, increases 5-ht levels in the hippocampus and in the nac, and 2.) |
2002-08-08 |
2023-08-12 |
rat |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
5-ht(1a)-receptor antagonism can cause a dissociation of the hippocampal and nac 5-ht activity from behavioral activation after cocaine. |
2002-08-08 |
2023-08-12 |
rat |
| Stephen E Alves, Elena Hoskin, Susan J Lee, Wayne G Brake, Deveroux Ferguson, Victoria Luine, Patrick B Allen, Paul Greengard, Bruce S McEwe. Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112407. |
serotonin mediates ca1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. |
2002-08-08 |
2023-08-12 |
rat |
| Stephen E Alves, Elena Hoskin, Susan J Lee, Wayne G Brake, Deveroux Ferguson, Victoria Luine, Patrick B Allen, Paul Greengard, Bruce S McEwe. Serotonin mediates CA1 spine density but is not crucial for ovarian steroid regulation of synaptic plasticity in the adult rat dorsal hippocampus. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112407. |
we sought to determine whether 5-ht is involved in maintaining ca1 spine density and/or in steroid regulation of synaptic plasticity in dorsal hippocampus. |
2002-08-08 |
2023-08-12 |
rat |
| Michel B Emerit, Edith Doucet, Michèle Darmon, Michel Hamo. Native and cloned 5-HT(3A)(S) receptors are anchored to F-actin in clonal cells and neurons. Molecular and cellular neurosciences. vol 20. issue 1. 2002-08-07. PMID:12056843. |
colocalization and coclustering of 5-ht(3a)(s) subunits and f-actin were also observed in transfected hippocampal neurons. |
2002-08-07 |
2023-08-12 |
Not clear |
| Susana Esteban, David Moranta, Antoni Sastre-Coll, Antonio Miralles, Jesús A García-Sevill. Withdrawal from chronic ethanol increases the sensitivity of presynaptic 5-HT(1A) receptors modulating serotonin and dopamine synthesis in rat brain in vivo. Neuroscience letters. vol 326. issue 2. 2002-08-06. PMID:12057843. |
similar effects were induced by the mixed 5-ht(1a) agonist/d(2) antagonist buspirone (1 mg/kg, i.p., 1 h) which also decreased 5-htp synthesis in the hippocampus (24%), cerebral cortex (36%) and striatum (35%) of chronic ethanol-withdrawn rats. |
2002-08-06 |
2023-08-12 |
rat |
| R Mössner, R Dringen, A M Persico, B Janetzky, O Okladnova, D Albert, M Götz, J Benninghoff, A Schmitt, M Gerlach, P Riederer, K P Lesc. Increased hippocampal DNA oxidation in serotonin transporter deficient mice. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111449. |
increased hippocampal dna oxidation in serotonin transporter deficient mice. |
2002-08-06 |
2023-08-12 |
mouse |
| R Mössner, R Dringen, A M Persico, B Janetzky, O Okladnova, D Albert, M Götz, J Benninghoff, A Schmitt, M Gerlach, P Riederer, K P Lesc. Increased hippocampal DNA oxidation in serotonin transporter deficient mice. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111449. |
given the importance of the hippocampus in learning and memory, this may be the most important neurochemical consequence of the absence of the 5htt. |
2002-08-06 |
2023-08-12 |
mouse |
| Patricia Tagliaferro, Maita Duhalde Vega, Sergio Gustavo Evrard, Alberto Javier Ramos, Alicia Brusc. Alcohol exposure during adulthood induces neuronal and astroglial alterations in the hippocampal CA-1 area. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105109. |
the aim of the present work was to study the morphologic alterations of glial cells and neurons on the hippocampus after long-term etoh exposure using gfap and s-100 beta protein, neurofilaments of 200 kda (nf200), map2, and serotonin transporter (5ht-t) immunocytochemical staining. |
2002-08-02 |
2023-08-12 |
rat |
| Alberto Javier Ramos, Sergio Gustavo Evrard, Patricia Tagliaferro, María Victoria Tricárico, Alicia Brusc. Effects of chronic maternal ethanol exposure on hippocampal and striatal morphology in offspring. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105110. |
our results show that astroglial gfap was increased (astrocytes were hypertrophied) and 5htt(+) fibers were increased in both the hippocampal ca-1 area and the striatum. |
2002-08-02 |
2023-08-12 |
rat |
| Jerrold S Meyer, Syed F Al. Serotonergic neurotoxicity of MDMA (ecstasy) in the developing rat brain. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105113. |
pups subsequently remained undisturbed until sacrifice at pd 25 and pd 60 for assessment of serotonergic damage by measuring 5-ht transporter (sert) binding in the hippocampus and neocortex as well as 5-ht and 5-hiaa concentrations (pd 25 only). |
2002-08-02 |
2023-08-12 |
rat |
| Jerrold S Meyer, Syed F Al. Serotonergic neurotoxicity of MDMA (ecstasy) in the developing rat brain. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105113. |
neonatal mdma exposure led to significant reductions in both sert binding and 5-ht levels in the hippocampus at pd 25, independent of body temperature during treatment. |
2002-08-02 |
2023-08-12 |
rat |