| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L P Reagan, H B Cowan, J L Woodruff, G G Piroli, J M Erichsen, A N Evans, H E Burzynski, N D Maxwell, F Z Loyo-Rosado, V A Macht, C A Grill. Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy. Neurobiology of stress. vol 15. 2021-07-15. PMID:34258333. |
in conclusion, hippocampal-specific insulin resistance elicits structural deficits that are accompanied by behavioral despair and anxiety-like behaviors, identifying hippocampal insulin resistance as a key factor in depressive illness. |
2021-07-15 |
2023-08-13 |
rat |
| IbDanelo Cortez, Caterina M Hernandez, Kelly T Dinele. Enhancement of select cognitive domains with rosiglitazone implicates dorsal hippocampus circuitry sensitive to PPARγ agonism in an Alzheimer's mouse model. Brain and behavior. vol 11. issue 2. 2021-06-30. PMID:33382528. |
in ad mouse models with concomitant insulin resistance, we have shown that 4 weeks of rsg can reverse peripheral and central insulin resistance concomitant with rescue of hippocampus-dependent fear learning and memory and hippocampal circuitry deficits in 9-month-old (9mo) tg2576 mice with no effect in wild-type (wt) mice. |
2021-06-30 |
2023-08-13 |
mouse |
| Fateme Binayi, Homeira Zardooz, Rasoul Ghasemi, Mehdi Hedayati, Sahar Askari, Ramin Pouriran, Mohammad Sahrae. The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. Physiology & behavior. vol 231. 2021-06-25. PMID:33412188. |
the chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. |
2021-06-25 |
2023-08-13 |
rat |
| Fateme Binayi, Homeira Zardooz, Rasoul Ghasemi, Mehdi Hedayati, Sahar Askari, Ramin Pouriran, Mohammad Sahrae. The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. Physiology & behavior. vol 231. 2021-06-25. PMID:33412188. |
this study assessed the effect of a chronic high-fat diet (hfd) on plasma and hippocampal insulin and corticosterone levels, the hippocampus insulin receptor amount, and spatial learning and memory with or without receiving 4-phenyl butyric acid (4-pba) in male rats. |
2021-06-25 |
2023-08-13 |
rat |
| Fateme Binayi, Homeira Zardooz, Rasoul Ghasemi, Mehdi Hedayati, Sahar Askari, Ramin Pouriran, Mohammad Sahrae. The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. Physiology & behavior. vol 231. 2021-06-25. PMID:33412188. |
then the hippocampus bip, chop, insulin, corticosterone, and insulin receptor levels were determined. |
2021-06-25 |
2023-08-13 |
rat |
| Fateme Binayi, Homeira Zardooz, Rasoul Ghasemi, Mehdi Hedayati, Sahar Askari, Ramin Pouriran, Mohammad Sahrae. The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. Physiology & behavior. vol 231. 2021-06-25. PMID:33412188. |
it decreased plasma insulin, and insulin content, and its receptor amount in hippocampus. |
2021-06-25 |
2023-08-13 |
rat |
| Fateme Binayi, Homeira Zardooz, Rasoul Ghasemi, Mehdi Hedayati, Sahar Askari, Ramin Pouriran, Mohammad Sahrae. The chemical chaperon 4-phenyl butyric acid restored high-fat diet- induced hippocampal insulin content and insulin receptor level reduction along with spatial learning and memory deficits in male rats. Physiology & behavior. vol 231. 2021-06-25. PMID:33412188. |
chronic hfd possibly through the induction of endoplasmic reticulum (er) stress and subsequent changes in the levels of hippocampal corticosterone, insulin and insulin receptor along with possible leptin resistance caused spatial learning and memory deficits. |
2021-06-25 |
2023-08-13 |
rat |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and bdnf signaling pathways in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
this study investigates if memory impairment and depressive-like phenotype are accompanied by the hippocampal insulin and bdnf signaling in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Vanessa Angonesi Zborowski, Suélen Osório Heck, Luiza Souza Marques, Nícolas Klummer Bastos, Cristina Wayne Nogueir. Memory impairment and depressive-like phenotype are accompanied by downregulation of hippocampal insulin and BDNF signaling pathways in prediabetic mice. Physiology & behavior. vol 237. 2021-06-25. PMID:33545209. |
the molecular findings indicate the downregulation of hippocampal insulin and bdnf signaling in prediabetic mice. |
2021-06-25 |
2023-08-13 |
mouse |
| Emmanuel O Yawson, Oluwole B Akinol. Hippocampal cellular changes in androgen deprived insulin resistant rats. Metabolic brain disease. vol 36. issue 5. 2021-06-22. PMID:33666820. |
hippocampal cellular changes in androgen deprived insulin resistant rats. |
2021-06-22 |
2023-08-13 |
rat |
| Emmanuel O Yawson, Oluwole B Akinol. Hippocampal cellular changes in androgen deprived insulin resistant rats. Metabolic brain disease. vol 36. issue 5. 2021-06-22. PMID:33666820. |
that the summate effects of androgen deprivation and impaired insulin signaling exacerbate hippocampal neurodegenerative changes that merit further studies. |
2021-06-22 |
2023-08-13 |
rat |
| Mai Marie Hol. Insulin as a potent bidirectional regulator of GABAergic signalling in the hippocampus of an Alzheimer's disease mouse model. Acta physiologica (Oxford, England). vol 232. issue 2. 2021-06-22. PMID:33830635. |
insulin as a potent bidirectional regulator of gabaergic signalling in the hippocampus of an alzheimer's disease mouse model. |
2021-06-22 |
2023-08-13 |
mouse |
| Ricardo Augusto Leoni De Sousa, Alex Cleber Improta-Caria, Francine Menezes de Jesus-Silva, Caique Olegário Diniz E Magalhães, Daniel Almeida Freitas, Ana Cristina Rodrigues Lacerda, Vanessa Amaral Mendonça, Ricardo Cardoso Cassilhas, Hércules Ribeiro Leit. High-intensity resistance training induces changes in cognitive function, but not in locomotor activity or anxious behavior in rats induced to type 2 diabetes. Physiology & behavior. vol 223. 2021-06-21. PMID:32505787. |
de group showed a reduction in the inhibition of the activation of hippocampal irs-1 and higher expression of gsk3β phosphorylated in serine compared to d group, revealing insulin signaling impairment, and neuronal death were identified in the hippocampus of d group. |
2021-06-21 |
2023-08-13 |
rat |
| Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain insulin resistance impairs hippocampal plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723548. |
brain insulin resistance impairs hippocampal plasticity. |
2021-06-21 |
2023-08-13 |
Not clear |
| Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain insulin resistance impairs hippocampal plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723548. |
in particular, insulin signaling has been shown to impact on molecular cascades underlying hippocampal plasticity, learning and memory. |
2021-06-21 |
2023-08-13 |
Not clear |
| Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain insulin resistance impairs hippocampal plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723548. |
alteration of brain insulin signaling interferes with the maintenance of neural stem cell niche and neuronal activity in the hippocampus. |
2021-06-21 |
2023-08-13 |
Not clear |
| Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain insulin resistance impairs hippocampal plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723548. |
here, we review the molecular mechanisms involved in the insulin modulation of both adult neurogenesis and synaptic activity in the hippocampus. |
2021-06-21 |
2023-08-13 |
Not clear |
| Matteo Spinelli, Salvatore Fusco, Claudio Grass. Brain insulin resistance impairs hippocampal plasticity. Vitamins and hormones. vol 114. 2021-06-21. PMID:32723548. |
we also summarize the effects of altered insulin sensitivity on hippocampal plasticity. |
2021-06-21 |
2023-08-13 |
Not clear |
| Stephanie M Garcia, Pamela R Hirschberg, Pallabi Sarkar, Dashiel M Siegel, Suraj B Teegala, Gwyndolin M Vail, Vanessa H Rout. Insulin actions on hypothalamic glucose-sensing neurones. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33507001. |
to conclude, electrophysiological data from the hippocampus are evaluated aiming to provide clues regarding how insulin might influence neuronal plasticity in glucose-sensing neurones. |
2021-06-15 |
2023-08-13 |
Not clear |