| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Crystal M Wilkie, Jocelyn R Barnes, Cherry-Lynn M Benson, Kyle J Brymer, Firoozeh Nafar, Matthew P Parson. Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354757. |
using electrophysiology and high-speed imaging of the glutamate biosensor iglusnfr, we quantified real-time glutamate dynamics and synaptic plasticity in the hippocampus of the q175fdn mouse model of hd, following intraperitoneal injections of either saline or ceftriaxone. |
2021-06-18 |
2023-08-13 |
mouse |
| Crystal M Wilkie, Jocelyn R Barnes, Cherry-Lynn M Benson, Kyle J Brymer, Firoozeh Nafar, Matthew P Parson. Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354757. |
we observed an activity-dependent increase in extracellular glutamate accumulation within the hd hippocampus, which was not the result of reduced glt-1 expression. |
2021-06-18 |
2023-08-13 |
mouse |
| Crystal M Wilkie, Jocelyn R Barnes, Cherry-Lynn M Benson, Kyle J Brymer, Firoozeh Nafar, Matthew P Parson. Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354757. |
these data provide evidence for glutamate dysregulation in the hd hippocampus but also caution the use of ceftriaxone as a treatment for hd. |
2021-06-18 |
2023-08-13 |
mouse |
| Frédéric Briend, Eric A Nelson, Omar Maximo, William P Armstrong, Nina V Kraguljac, Adrienne C Laht. Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32398671. |
hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis. |
2021-06-18 |
2023-08-13 |
human |
| Frédéric Briend, Eric A Nelson, Omar Maximo, William P Armstrong, Nina V Kraguljac, Adrienne C Laht. Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32398671. |
here, we quantify left hippocampus glutamate (glx) and left hippocampus subfield volumes in 54 antipsychotic-naive fep and 41 healthy controls (hc), matched on age, sex, and parental occupation. |
2021-06-18 |
2023-08-13 |
human |
| Anna Rita Zuena, Paola Casolini, Aldina Venerosi, Giovanni Sebastiano Alemà, Ferdinando Nicoletti, Gemma Calamandre. Selective reduction in the expression of type-1 metabotropic glutamate receptors in the hippocampus of adult rats born by caesarean section. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 4. 2021-06-17. PMID:33759234. |
selective reduction in the expression of type-1 metabotropic glutamate receptors in the hippocampus of adult rats born by caesarean section. |
2021-06-17 |
2023-08-13 |
rat |
| Shuwei Hu, Yiwen Yi, Tao Jiang, Zhexiao Jiao, Shiyun Dai, Xiaohan Gong, Ke Li, Hui Wang, Dan X. Intrauterine RAS programming alteration-mediated susceptibility and heritability of temporal lobe epilepsy in male offspring rats induced by prenatal dexamethasone exposure. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32494933. |
expression of hippocampal glucocorticoid receptor (gr), ccaat enhancer-binding protein α (c/ebpα), intrauterine renin-angiotensin system (ras) classical pathway related genes, the h3k27ac level in angiotensin-converting enzyme (ace) promoter, as well as high mobility group box 1 (hmgb1) and toll-like receptor 4 (tlr4) were increased, but glutamate dehydrogenase (glud) 1/2 expression were decreased, accompanied by increased glutamate levels in pde fetal and adult rats, as well as in f1 and f2 offspring of the pde + lipc group. |
2021-06-16 |
2023-08-13 |
rat |
| A L Proskura, M Yu Islamova, S O Vechkapov. [Cross-Talk of the Glutamate and Leptin Receptor Pathways]. Molekuliarnaia biologiia. vol 55. issue 3. 2021-06-09. PMID:34097685. |
a molecular mechanism of leptin effects in the hippocampus was assumed to involve a cross-talk of the molecular pathways of the leptin receptors and nmda-type glutamate receptors. |
2021-06-09 |
2023-08-13 |
Not clear |
| Daniel Tonial Thomaz, Rafaela Rafognatto Andreguetti, Luisa Bandeira Binder, Débora da Luz Scheffer, Alisson Willms Corrêa, Fátima Regina Mena Barreto Silva, Carla Inês Tasc. Guanosine Neuroprotective Action in Hippocampal Slices Subjected to Oxygen and Glucose Deprivation Restores ATP Levels, Lactate Release and Glutamate Uptake Impairment: Involvement of Nitric Oxide. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32666283. |
guanosine neuroprotective action in hippocampal slices subjected to oxygen and glucose deprivation restores atp levels, lactate release and glutamate uptake impairment: involvement of nitric oxide. |
2021-06-08 |
2023-08-13 |
rat |
| Sinead E Shortall, Angus M Brown, Eliot Newton-Mann, Erin Dawe-Lane, Chanelle Evans, Maxine Fowler, Madeleine V Kin. Calbindin Deficits May Underlie Dissociable Effects of 5-HT Molecular neurobiology. vol 57. issue 8. 2021-06-07. PMID:32533466. |
glutamatergic dysfunction contributes to schizophrenia pathophysiology and may represent a treatment target, so we used enzyme-based microsensors to evaluate basal- and drug-evoked glutamate release in hippocampal slices from rats that received neonatal pcp and/or isolation rearing. |
2021-06-07 |
2023-08-13 |
rat |
| Oluwole Ojo Alese, Cleopatra Rakgantsho, Nombuso V Mkhize, Simo Zulu, Musa V Mabandl. Prolonged febrile seizure history exacerbates seizure severity in a pentylenetetrazole rat model of epilepsy. Brain research bulletin. vol 155. 2021-06-03. PMID:31837458. |
we also observed it effect on the hippocampal glial fibrillary acidic protein (gfap), synaptophysin and metabotropic glutamate receptor 3 (mglur3) expression measured with immunofluorescence, li cor tissue florescence and immunohistochemistry respectively. |
2021-06-03 |
2023-08-13 |
rat |
| Mohsen Shamsi, Maliheh Soodi, Shirin Shahbazi, Ameneh Omid. Effect of Acetamiprid on spatial memory and hippocampal glutamatergic system. Environmental science and pollution research international. vol 28. issue 22. 2021-06-03. PMID:33523378. |
in addition, glutamate level and changes in the expression of nr1, nr2, and nr2b genes were measured in the hippocampus; also, the hippocampus tissue was histologically evaluated. |
2021-06-03 |
2023-08-13 |
rat |
| Mohsen Shamsi, Maliheh Soodi, Shirin Shahbazi, Ameneh Omid. Effect of Acetamiprid on spatial memory and hippocampal glutamatergic system. Environmental science and pollution research international. vol 28. issue 22. 2021-06-03. PMID:33523378. |
in all acetamiprid-treated groups, a significant reduction of glutamate level in the hippocampus was observed (p < 0.05). |
2021-06-03 |
2023-08-13 |
rat |
| Mohsen Shamsi, Maliheh Soodi, Shirin Shahbazi, Ameneh Omid. Effect of Acetamiprid on spatial memory and hippocampal glutamatergic system. Environmental science and pollution research international. vol 28. issue 22. 2021-06-03. PMID:33523378. |
the results of the present study indicate that acetamiprid impairs memory consolidation through the reduction of glutamate and the expression of nmda receptor subunits in the hippocampus at low doses, along with the loss of neural cells in dentate gyrus at high dose. |
2021-06-03 |
2023-08-13 |
rat |
| Justyna Pyrzanowska, Ilona Joniec-Maciejak, Kamilla Blecharz-Klin, Agnieszka Piechal, Dagmara Mirowska-Guzel, Izabela Fecka, Ewa Widy-Tyszkiewic. Aspalathus linearis infusion affects hole-board test behaviour and amino acid concentration in the brain. Neuroscience letters. vol 747. 2021-06-03. PMID:33529651. |
excitatory amino acids (aspartate and glutamate) content was decreased in the striatum of animals drinking the infusions whereas taurine level was increased both in the striatum and hippocampus. |
2021-06-03 |
2023-08-13 |
rat |
| Haiyang Zhang, Wenjing Jiao, Hailin Cui, Qinghong Sun, Honggang Fa. Combined exposure of alumina nanoparticles and chronic stress exacerbates hippocampal neuronal ferroptosis via activating IFN-γ/ASK1/JNK signaling pathway in rats. Journal of hazardous materials. vol 411. 2021-06-03. PMID:33858114. |
both alnps and crs induced hippocampal neuronal ferroptosis, presenting as iron and glutamate metabolism disorder, gpx4 fluorescence of neurons decrease, lpo and ros levels increase, and fjb-positive neurons increase. |
2021-06-03 |
2023-08-13 |
rat |
| T V Davydova, M A Gruden, V S Kudrin, V B Narkevich, L A Vetrile, I A Zakharova, R D E Sewel. Antibodies to Glutamate Facilitate Spatial Memory Formation in the Morris Water Maze in Aging C57BL/6 mice. Bulletin of experimental biology and medicine. vol 169. issue 1. 2021-06-01. PMID:32474668. |
in animals treated with glutamate antibodies, the content of serotonin and dopamine metabolites 3-mt and hva in the hippocampus decreased, but no changes in the metabolism of neurotransmitter acids were revealed. |
2021-06-01 |
2023-08-13 |
mouse |
| Jenna C Hebert, Daniel E Radford-Smith, Fay Probert, Nicholas Ilott, Ka Wai Chan, Daniel C Anthony, Philip W J Burne. Mom's diet matters: Maternal prebiotic intake in mice reduces anxiety and alters brain gene expression and the fecal microbiome in offspring. Brain, behavior, and immunity. vol 91. 2021-05-27. PMID:33031920. |
maternal b-gos supplementation increased exploratory behavior and reduced expression of hippocampal glutamate receptor genes in young, weaning-age offspring. |
2021-05-27 |
2023-08-13 |
mouse |
| Eriko Sugano, Yuka Endo, Akihisa Sugai, Yuki Kikuchi, Kitako Tabata, Taku Ozaki, Takahiro Kurose, Yoshihiro Takai, Yoko Mitsuguchi, Yoichi Honma, Hiroshi Tomit. Geranylgeranyl acetone prevents glutamate-induced cell death in HT-22 cells by increasing mitochondrial membrane potential. European journal of pharmacology. vol 883. 2021-05-18. PMID:32659301. |
glutamate exposure was lethal to ht-22 cells which comprise a neuronal line derived from mouse hippocampus. |
2021-05-18 |
2023-08-13 |
mouse |
| Remy Verhaeghe, Vance Gao, Sara Morley-Fletcher, Hammou Bouwalerh, Gilles Van Camp, Francesca Cisani, Ferdinando Nicoletti, Stefania Maccar. Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats. GeroScience. 2021-05-15. PMID:33983623. |
prs induced large reductions in the expression of glutamate receptors in the ventral and dorsal hippocampus and prefrontal cortex only in male rats. |
2021-05-15 |
2023-08-13 |
rat |