| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gustavo A Chiprés-Tinajero, Miguel A Núñez-Ochoa, Laura Medina-Cej. Increased immunoreactivity of glutamate receptors, neuronal nuclear protein and glial fibrillary acidic protein in the hippocampus of epileptic rats with fast ripple activity. Experimental brain research. vol 239. issue 6. 2021-07-28. PMID:33909110. |
these results suggest an important role of glutamate receptors in the hippocampus of epileptic rats with fr activity. |
2021-07-28 |
2023-08-13 |
rat |
| Radu Gugustea, Zhengping Ji. Genetic manipulations of AMPA glutamate receptors in hippocampal synaptic plasticity. Neuropharmacology. vol 194. 2021-07-28. PMID:34089730. |
genetic manipulations of ampa glutamate receptors in hippocampal synaptic plasticity. |
2021-07-28 |
2023-08-13 |
mouse |
| Ji Yun Baek, Kiwon Jung, Young-Mi Kim, Hyun-Young Kim, Ki Sung Kang, Young-Won Chi. Protective Effect of γ-mangostin Isolated from the Peel of Biomolecules. vol 11. issue 2. 2021-07-23. PMID:33514017. |
to investigate the effect of γ-mangostin on apoptosis, 5 mm of glutamate was used to induce apoptotic cell death in mouse hippocampal ht22 cells. |
2021-07-23 |
2023-08-13 |
mouse |
| Kotaro Sakamoto, Daisuke Yamada, Nanami Yamanaka, Moeno Nishida, Keita Iio, Hiroshi Nagase, Akiyoshi Saito. A selective delta opioid receptor agonist SNC80, but not KNT-127, induced tremor-like behaviors via hippocampal glutamatergic system in mice. Brain research. vol 1757. 2021-07-23. PMID:33516811. |
further, the extracellular glutamate levels in the hippocampus were significantly lower in the knt-127-treated mice than in the snc80-treated mice. |
2021-07-23 |
2023-08-13 |
mouse |
| Andre U Deutschmann, Julia M Kirkland, Lisa A Brian. Adolescent social isolation induced alterations in nucleus accumbens glutamate signalling. Addiction biology. 2021-07-19. PMID:34278652. |
in summary, we demonstrate that social isolation rearing leads to alterations in glutamate transmission driven by projections from the ventral hippocampus. |
2021-07-19 |
2023-08-13 |
mouse |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. |
2021-07-16 |
2023-08-13 |
mouse |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
here, we first asked whether mice with a homozygous deletion of glud1 in cns (cns-glud1 -/- mice) express different levels of glutamate in hippocampus, and found elevated glutamate as well as glutamine in dorsal and ventral hippocampus, and increased glutamine in medial prefrontal cortex (mpfc). |
2021-07-16 |
2023-08-13 |
mouse |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
l-serine and d-serine, which contribute to glutamate homeostasis and nmda receptor function, are increased in ventral but not dorsal hippocampus, and in mpfc. |
2021-07-16 |
2023-08-13 |
mouse |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
protein expression levels of the gaba synthesis enzyme glutamate decarboxylase (gad) gad67 were decreased in the ventral hippocampus as well. |
2021-07-16 |
2023-08-13 |
mouse |
| Sharon Sima Lander, Sergiy Chornyy, Hazem Safory, Amit Gross, Herman Wolosker, Inna Gaisler-Salomo. Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:31898404. |
these data point to hippocampal subregion-dependent disruption in glutamate homeostasis and excitatory/inhibitory balance, and to behavioral deficits that support a decline in hippocampal-prefrontal cortex connectivity. |
2021-07-16 |
2023-08-13 |
mouse |
| Kate Beecher, Joshua Wang, Angela Jacques, Nicholas Chaaya, Fatemeh Chehrehasa, Arnauld Belmer, Selena E Bartlet. Sucrose Consumption Alters Serotonin/Glutamate Co-localisation Within the Prefrontal Cortex and Hippocampus of Mice. Frontiers in molecular neuroscience. vol 14. 2021-07-16. PMID:34262435. |
although serotonin and glutamate co-localisation has been implicated in reward processing, it is still unknown how chronic sucrose consumption changes this transmission in regions associated with executive control over feeding-such as the prefrontal cortex (pfc) and dentate gyrus (dg) of the hippocampus. |
2021-07-16 |
2023-08-13 |
mouse |
| Veronika A Nikitina, Maria V Zakharova, Alexander N Trofimov, Alexander P Schwarz, Gleb V Beznin, Sergei G Tsikunov, Olga E Zubarev. Neonatal Exposure to Bacterial Lipopolysaccharide Affects Behavior and Expression of Ionotropic Glutamate Receptors in the Hippocampus of Adult Rats after Psychogenic Trauma. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225597. |
neonatal exposure to bacterial lipopolysaccharide affects behavior and expression of ionotropic glutamate receptors in the hippocampus of adult rats after psychogenic trauma. |
2021-07-15 |
2023-08-13 |
rat |
| Veronika A Nikitina, Maria V Zakharova, Alexander N Trofimov, Alexander P Schwarz, Gleb V Beznin, Sergei G Tsikunov, Olga E Zubarev. Neonatal Exposure to Bacterial Lipopolysaccharide Affects Behavior and Expression of Ionotropic Glutamate Receptors in the Hippocampus of Adult Rats after Psychogenic Trauma. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225597. |
here, we studied expression of nmda (glun1, glun2a, glun2b) and ampa (glua1, glua2) glutamate receptor subunits, as well as glutamate transporter eaat2, in the ventral and dorsal regions of the hippocampus of rats injected with lps during the third postnatal week and then subjected to predator stress (contact with a python) in adulthood. |
2021-07-15 |
2023-08-13 |
rat |
| Veronika A Nikitina, Maria V Zakharova, Alexander N Trofimov, Alexander P Schwarz, Gleb V Beznin, Sergei G Tsikunov, Olga E Zubarev. Neonatal Exposure to Bacterial Lipopolysaccharide Affects Behavior and Expression of Ionotropic Glutamate Receptors in the Hippocampus of Adult Rats after Psychogenic Trauma. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225597. |
to summarize the results of our study, exposure to bacterial lps in the early postnatal ontogenesis affects the pattern of stress-induced changes in the behavior and hippocampal expression of genes coding for ionotropic glutamate receptor subunits after psychogenic trauma suffered in adulthood. |
2021-07-15 |
2023-08-13 |
rat |
| Ibrahim Khan, Kamran Saeed, Min Gi Jo, Myeong Ok Ki. 17-β Estradiol Rescued Immature Rat Brain against Glutamate-Induced Oxidative Stress and Neurodegeneration via Regulating Nrf2/HO-1 and MAP-Kinase Signaling Pathway. Antioxidants (Basel, Switzerland). vol 10. issue 6. 2021-07-10. PMID:34206065. |
moreover, exogenous glutamate also reduced the expression of synaptic markers (psd-95, syp) and induced apoptotic neurodegeneration in the cortical and hippocampal regions by dysregulating the expression of bax, bcl-2 and caspase-3 in the developing rat brain. |
2021-07-10 |
2023-08-13 |
human |
| Yun Fan, Mei-Chuan Chou, Yen-Chin Liu, Ching-Kuan Liu, Chu-Huang Chen, Shiou-Lan Che. Intermittent Hypoxia Activates N-Methyl-D-Aspartate Receptors to Induce Anxiety Behaviors in a Mouse Model of Sleep-Associated Apnea. Molecular neurobiology. vol 58. issue 7. 2021-07-06. PMID:33660202. |
increased glutamate n-methyl-d-aspartate (nmda) receptor subunits 2b (glun2b) and phosphorylated-erk1/2 were seen in the mpfc, striatum, and hippocampus of ih mice, but no significant microglial and astrocyte activation was found in these brain areas. |
2021-07-06 |
2023-08-13 |
mouse |
| Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F Traynelis, Yong Chul Bae, Se-Young Choi, C Justin Le. Correction to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Molecular brain. vol 14. issue 1. 2021-07-03. PMID:34187529. |
correction to: channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic nmda receptors. |
2021-07-03 |
2023-08-13 |
Not clear |
| Ju Hwan Kim, Kyung Hwun Chung, Yeong Ran Hwang, Hye Ran Park, Hee Jung Kim, Hyung-Gun Kim, Hak Rim Ki. Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice. International journal of molecular sciences. vol 22. issue 10. 2021-07-02. PMID:34069478. |
the expression of glutamate receptors was decreased in mushroom-type dendritic spines in the ca1 and dg of hippocampal neurons following rf-emf exposure. |
2021-07-02 |
2023-08-13 |
mouse |
| Philemon D Shallie, Adedeji I Sulaiman, Motunrayo K Oladejo, Oluwadamilola F Shallie, Thajasvarie Naicke. Early glutathione intervention educed positive correlation between VGLUT1 expression and spatial memory in the Nω-nitro-L-arginine methyl rat model of IUGR. IBRO neuroscience reports. vol 10. 2021-06-29. PMID:34179867. |
therefore, this study investigated the effects of postnatal glutathione intervention on the spatial memory and the expressions of vesicular glutamate transporter 1 (vglut1) in the hippocampus and the cerebellar cortex of nω-nitro-l-arginine methyl (l-name)-induced rat model of iugr. |
2021-06-29 |
2023-08-13 |
rat |
| Romain Troubat, Pascal Barone, Samuel Leman, Thomas Desmidt, Arnaud Cressant, Boriana Atanasova, Bruno Brizard, Wissam El Hage, Alexandre Surget, Catherine Belzung, Vincent Camu. Neuroinflammation and depression: A review. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:32150310. |
it is reported that kynurenine (kyn) pathway alteration in favour of its excitotoxic component and hpa axis dysregulation have the common effect of increasing extracellular glutamate levels and glutamate neurotransmission, which can impact hippocampal neurogenesis. |
2021-06-28 |
2023-08-13 |
Not clear |