| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroki Yasuda, Hikaru Yamamoto, Kenji Hanamura, Mona Mehruba, Toshio Kawamata, Hiromi Morisaki, Masaaki Miyamoto, Shinji Takada, Tomoaki Shirao, Yoshitaka Ono, Hideyuki Muka. PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation. Communications biology. vol 3. issue 1. 2021-06-25. PMID:33244074. |
knocking out pkn1a decreased hippocampal eaat3 expression and pkn1 inhibition reduced glutamate uptake through eaat3. |
2021-06-25 |
2023-08-13 |
mouse |
| N L Mason, K P C Kuypers, F Müller, J Reckweg, D H Y Tse, S W Toennes, N R P W Hutten, J F A Jansen, P Stiers, A Feilding, J G Ramaeker. Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 12. 2021-06-23. PMID:32446245. |
whereas higher levels of medial prefrontal cortical glutamate were associated with negatively experienced ego dissolution, lower levels in hippocampal glutamate were associated with positively experienced ego dissolution. |
2021-06-23 |
2023-08-13 |
Not clear |
| Daniel Ramandi, Mahmoud Elahdadi Salmani, Ali Moghimi, Taghi Lashkarbolouki, Masoud Fereidon. Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of temporal lobe epilepsy. PloS one. vol 16. issue 1. 2021-06-23. PMID:33507976. |
our results demonstrated that the acute phase of epileptogenesis (first 72 hours after status epilepticus) was accompanied by an increase in the hippocampal glutamate and downregulation of glt-1 mrna expression compared to controls. |
2021-06-23 |
2023-08-13 |
Not clear |
| Daniel Ramandi, Mahmoud Elahdadi Salmani, Ali Moghimi, Taghi Lashkarbolouki, Masoud Fereidon. Pharmacological upregulation of GLT-1 alleviates the cognitive impairments in the animal model of temporal lobe epilepsy. PloS one. vol 16. issue 1. 2021-06-23. PMID:33507976. |
this study shows that astrocytic glutamate uptake can profoundly impact the processes of hippocampal epileptogenesis through the reduction of glutamate-induced excitotoxicity and consequently rescuing of cognitive deficits caused by epilepsy. |
2021-06-23 |
2023-08-13 |
Not clear |
| Baskar Selvaraj, Uyen Tran Tu Nguyen, Gyewon Huh, Duc Hung Nguyen, Il-Kyoon Mok, Heesu Lee, Kyungsu Kang, Ae Nim Bae, Dae Won Kim, Jae Wook Le. Synthesis and biological evaluation of chalcone derivatives as neuroprotective agents against glutamate-induced HT22 mouse hippocampal neuronal cell death. Bioorganic & medicinal chemistry letters. vol 30. issue 22. 2021-06-22. PMID:33022369. |
seventeen chalcone analogues were synthesized from 7-methoxy-3,4-dihydronaphthalen1(2h)-one and various aromatic aldehydes under basic conditions and their therapeutic properties were studied in mouse hippocampal cell line ht-22 against neuronal cell death induced by glutamate. |
2021-06-22 |
2023-08-13 |
mouse |
| Karina Festerling, Karolina Can, Sebastian Kügler, Michael Mülle. Overshooting Subcellular Redox-Responses in Rett-Mouse Hippocampus during Neurotransmitter Stimulation. Cells. vol 9. issue 12. 2021-06-22. PMID:33255426. |
the rogfp redox sensor was expressed in either the cytosol or the mitochondrial matrix of cultured mouse hippocampal neurons, and the responses to transient stimulation by glutamate, serotonin, dopamine and norepinephrine were characterized. |
2021-06-22 |
2023-08-13 |
mouse |
| K Nordengen, C Morland, B S Slusher, V Gunderse. Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 3. 2021-06-21. PMID:31504271. |
in acute hippocampal slices, naag was depleted from postsynaptic dendritic elements during neuronal stimulation induced by depolarizing concentrations of potassium or by exposure to glutamate receptor (glur) agonists. |
2021-06-21 |
2023-08-13 |
rat |
| Morgan Bridi, Hannah Schoch, Cédrick Florian, Shane G Poplawski, Anamika Banerjee, Joshua D Hawk, Giulia S Porcari, Camille Lejards, Chang-Gyu Hahn, Karl-Peter Giese, Robbert Havekes, Nelson Spruston, Ted Abe. Transcriptional corepressor SIN3A regulates hippocampal synaptic plasticity via Homer1/mGluR5 signaling. JCI insight. vol 5. issue 5. 2021-06-21. PMID:32069266. |
loss of sin3a increases expression of the synaptic scaffold homer1, alters the metabotropic glutamate receptor 1α (mglur1α) and mglur5 dependence of long-term potentiation, and increases activation of erk in the hippocampus after learning. |
2021-06-21 |
2023-08-13 |
Not clear |
| Zhijun Shen, Hariprakash Haragopal, Yang V L. Zinc modulates synaptic transmission by differentially regulating synaptic glutamate homeostasis in hippocampus. The European journal of neuroscience. vol 52. issue 7. 2021-06-21. PMID:32302450. |
zinc modulates synaptic transmission by differentially regulating synaptic glutamate homeostasis in hippocampus. |
2021-06-21 |
2023-08-13 |
Not clear |
| Valerie Treyer, Anton F Gietl, Husam Suliman, Esmeralda Gruber, Rafael Meyer, Andreas Buchmann, Anass Johayem, Paul G Unschuld, Roger M Nitsch, Alfred Buck, Simon M Ametamey, Christoph Hoc. Reduced uptake of [11C]-ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer's dementia. Brain and behavior. vol 10. issue 6. 2021-06-21. PMID:32304284. |
reduced uptake of [11c]-abp688, a pet tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in alzheimer's dementia. |
2021-06-21 |
2023-08-13 |
Not clear |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
d-lys-3-ghrp-6 impairs memory consolidation and downregulates the hippocampal serotonin ht1a, ht7 receptors and glutamate glua1 subunit of ampa receptors. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
we aimed to evaluate the effect of intracerebral injection of a ghrelin receptor antagonist (d-lys-3-ghrp-6) on memory consolidation in the inhibitory avoidance task and on the gene expression levels of serotonin ht1a and ht7 receptors, glutamate glun1 subunit of the nmda and glua1 subunit of the ampa receptors and calcium/calmodulin kinase ii-α in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
meanwhile, it led to a significant downregulation of the mrna expression levels of the hippocampal serotonin ht1a and ht7 receptors and glutamate glua1 subunit of the ampa receptors, but could not affect that of glun1 subunit of the nmda receptors and camkii-α. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
it seems that part of the impairing effect of d-lys-3-ghrp-6 on inhibitory avoidance memory consolidation might be due to a decrease in the expression of serotonin ht1a and ht7 receptors and glutamate ampa receptors in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
to understand the possible mechanisms, amyloid-β (aβ)-42, brain-derived neurotrophic factor (bdnf), glutamate, malondialdehyde (mda), tumor-necrosis-factor (tnf)-α, and interleukin (il)-6 levels were measured in the hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
the results of this study indicate that stz administration impaired cognitive functions, increased anxiety- and depression-related behaviors, and elevated aβ-42, glutamate, mda, tnf-α, and il-6 levels in the hippocampus of mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Hamideh Bashiri, Mohsen Enayati, Alireza Bashiri, Ali-Akbar Salar. Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease. Physiology & behavior. vol 223. 2021-06-21. PMID:32522682. |
in contrast, swimming exercise significantly reversed these neurobehavioral disorders, increased bdnf, and decreased both glutamate and tnf-α in the hippocampus of stz-treated mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Dušica Briševac, Ralf Scholz, Dan Du, Mohammad Nael Elagabani, Georg Köhr, Hans-Christian Korna. The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome. Journal of neurochemistry. vol 157. issue 3. 2021-06-21. PMID:33125726. |
here, we determined the fraction of active, gtp-bound arf6 in cortical neuron cultures and synaptoneurosomes from fmr1 knockout mice, measured actin polymerization in neurons expressing arf6 mutants with variant gtp- or gdp-binding properties, and recorded hippocampal long-term depression induced by metabotropic glutamate receptors (mglur-ltd) in acute brain slices. |
2021-06-21 |
2023-08-13 |
mouse |
| Zeinab Momeni, Maricris Bautista, Joseph Neapetung, Rylan Urban, Yasuhiko Yamamoto, Anand Krishnan, Verónica A Campanucc. RAGE signaling is required for AMPA receptor dysfunction in the hippocampus of hyperglycemic mice. Physiology & behavior. vol 229. 2021-06-21. PMID:33221393. |
in this study, we hypothesize that rage signaling alters glutamate receptor function and expression, impairing synaptic transmission in the hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |
| Peng Wang, Xiaoxia Gao, Fang Zhao, Yao Gao, Kexin Wang, Jun-Sheng Tian, Zhenyu Li, Xue-Mei Qi. Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis. ACS chemical neuroscience. vol 12. issue 12. 2021-06-21. PMID:34060807. |
compared with the control group, the levels of neurotransmitters including 5-hydroxytryptamine (5-ht), acetylcholine, glutamate (glu), and dopamine (da) in the hippocampus and 5-ht, norepinephrine, γ-aminobutyric acid (gaba), and 5-hydroxyindoleacetic acid in serum were significantly changed in the cums rats. |
2021-06-21 |
2023-08-13 |
rat |