| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Lorez, D Benke, B Luscher, H Mohler, J A Benso. Single-channel properties of neuronal GABAA receptors from mice lacking the 2 subunit. The Journal of physiology. vol 527 Pt 1. 2000-11-07. PMID:10944167. |
unitary currents were evoked by low concentrations of gaba (0.5-5 microm) in membrane patches from acutely isolated dorsal root ganglion (drg) neurones (postnatal day 0) and by 1 microm gaba in patches from embryonic hippocampal neurones which were cultured for up to 3 weeks. |
2000-11-07 |
2023-08-12 |
mouse |
| N Hájos, I Katona, S S Naiem, K MacKie, C Ledent, I Mody, T F Freun. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998107. |
we conclude that activation of presynaptic cb1 receptors decreases ca2+-dependent gaba release, and thereby reduces the power of hippocampal network oscillations. |
2000-11-07 |
2023-08-12 |
mouse |
| M L Kram, G L Kramer, M Steciuk, P J Ronan, F Pett. Effects of learned helplessness on brain GABA receptors. Neuroscience research. vol 38. issue 2. 2000-11-01. PMID:11000446. |
densities of gaba binding were measured in prefrontal cortex, septum, hippocampus, hypothalamus and amygdala. |
2000-11-01 |
2023-08-12 |
rat |
| J Zagrodzka, A Romaniuk, M Wieczorek, P Boguszewsk. Bicuculline administration into ventromedial hypothalamus: effects on fear and regional brain monoamines and GABA concentrations in rats. Acta neurobiologiae experimentalis. vol 60. issue 3. 2000-10-19. PMID:11016075. |
the effects of bicuculline methiodide administration into ventromedial hypothalamus (15 ng per site, bilaterally) on fear behavior and monoamines (na, da, 5-ht) and gaba in structures of the brain defensive system (hypothalamus, midbrain gray matter, amygdala, hippocampus and frontal cortex) were studied. |
2000-10-19 |
2023-08-12 |
rat |
| D K Meyer, C Olenik, F Hofmann, H Barth, J Leemhuis, I Brünig, K Aktories, W Nörenber. Regulation of somatodendritic GABAA receptor channels in rat hippocampal neurons: evidence for a role of the small GTPase Rac1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995817. |
the role of the cytoskeleton in the activity of gaba(a) receptors was investigated in cultured hippocampal neurons. |
2000-10-18 |
2023-08-12 |
rat |
| J Kapu. Hippocampal neurons express GABA A receptor insensitive to diazepam in hyperexcitable conditions. Epilepsia. vol 41 Suppl 6. 2000-10-17. PMID:10999526. |
hippocampal neurons express gaba a receptor insensitive to diazepam in hyperexcitable conditions. |
2000-10-17 |
2023-08-12 |
rat |
| I Podkletnova, R Mäkelä, E R Korpi, H Lüddens, P Helen, H Alh. Neonatal 6-hydroxydopamine treatment affects GABA(A) receptor subunit expression in the frontal cortex but not the hippocampus of rats during postnatal development. Developmental neuroscience. vol 22. issue 4. 2000-10-11. PMID:10965151. |
neonatal 6-hydroxydopamine treatment affects gaba(a) receptor subunit expression in the frontal cortex but not the hippocampus of rats during postnatal development. |
2000-10-11 |
2023-08-12 |
rat |
| I Podkletnova, R Mäkelä, E R Korpi, H Lüddens, P Helen, H Alh. Neonatal 6-hydroxydopamine treatment affects GABA(A) receptor subunit expression in the frontal cortex but not the hippocampus of rats during postnatal development. Developmental neuroscience. vol 22. issue 4. 2000-10-11. PMID:10965151. |
the influence of neonatal administration of 6-hydroxydopamine (6-ohda) on the maturation of gaba(a) receptors in the frontal cortex and hippocampus was studied using 5- to 40-day-old rats. |
2000-10-11 |
2023-08-12 |
rat |
| J Lameh, P Wang, D Elgart, D Meredith, S L Shafer, G H Loe. Unraveling the identity of benzodiazepine binding sites in rat hipppocampus and olfactory bulb. European journal of pharmacology. vol 400. issue 2-3. 2000-10-10. PMID:10988330. |
the goals of the work reported here were (i) to identify distinct gaba(a)/benzodiazepine receptors in the rat hippocampus and olfactory bulb using receptor binding assays, and (ii) to determine the affinities and selectivities of benzodiazepine receptor ligands from structurally diverse chemical families at each site identified. |
2000-10-10 |
2023-08-12 |
rat |
| Q Y Liu, A E Schaffner, Y H Chang, D Maric, J L Barke. Persistent activation of GABA(A) receptor/Cl(-) channels by astrocyte-derived GABA in cultured embryonic rat hippocampal neurons. Journal of neurophysiology. vol 84. issue 3. 2000-10-03. PMID:10980012. |
persistent activation of gaba(a) receptor/cl(-) channels by astrocyte-derived gaba in cultured embryonic rat hippocampal neurons. |
2000-10-03 |
2023-08-12 |
rat |
| C Frahm, D Engel, A Piechotta, U Heinemann, A Draguh. Presence of gamma-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus. Neuroscience letters. vol 288. issue 3. 2000-09-28. PMID:10889336. |
presence of gamma-aminobutyric acid transporter mrna in interneurons and principal cells of rat hippocampus. |
2000-09-28 |
2023-08-12 |
rat |
| C Frahm, D Engel, A Piechotta, U Heinemann, A Draguh. Presence of gamma-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus. Neuroscience letters. vol 288. issue 3. 2000-09-28. PMID:10889336. |
these data indicate that gaba transporters may be present in non-gabaergic projection cells of the rat hippocampus which contribute to the clearance of gaba from the extracellular space. |
2000-09-28 |
2023-08-12 |
rat |
| O Howell, J R Atack, D Dewar, R M McKernan, C Su. Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891610. |
density and pharmacology of alpha5 subunit-containing gaba(a) receptors are preserved in hippocampus of alzheimer's disease patients. |
2000-09-27 |
2023-08-12 |
human |
| O Howell, J R Atack, D Dewar, R M McKernan, C Su. Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients. Neuroscience. vol 98. issue 4. 2000-09-27. PMID:10891610. |
furthermore, saturation and competition experiments with [3h]l-655,708 and representative benzodiazepine site ligands revealed that alpha5 receptors in alzheimer's hippocampus have an alpha5beta2/3gamma2 pharmacology and structure as in control human brain.overall, the data reported here provide evidence for a specific expression and relative sparing of alpha5 subunit-containing gamma-aminobutyric acid type-a receptors in the hippocampus of alzheimer's patients. |
2000-09-27 |
2023-08-12 |
human |
| C F Poulsen, K N Christjansen, S Hastrup, L Hartvi. Identification and cloning of a gamma 3 subunit splice variant of the human GABA(A) receptor. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891602. |
cdna sequences encoding two forms of the gaba(a) gamma 3 receptor subunit were cloned from human hippocampus. |
2000-09-25 |
2023-08-12 |
human |
| M Eghbali, P W Gage, B Birni. Pentobarbital modulates gamma-aminobutyric acid-activated single-channel conductance in rat cultured hippocampal neurons. Molecular pharmacology. vol 58. issue 3. 2000-09-25. PMID:10953037. |
we examined the effect of a range of pentobarbital concentrations on 0.5 microm gamma-aminobutyric acid (gaba)-activated channels (10 +/- 1 ps) in inside-out or outside-out patches from rat cultured hippocampal neurons. |
2000-09-25 |
2023-08-12 |
rat |
| G V Obrocea, M E Morri. Comparison of changes evoked by GABA (gamma-aminobutyric acid) and anoxia in [K+]o, [Cl-]o, and [Na+]o in stratum pyramidale and stratum radiatum of the guinea pig hippocampus. Canadian journal of physiology and pharmacology. vol 78. issue 5. 2000-09-15. PMID:10841433. |
comparison of changes evoked by gaba (gamma-aminobutyric acid) and anoxia in [k+]o, [cl-]o, and [na+]o in stratum pyramidale and stratum radiatum of the guinea pig hippocampus. |
2000-09-15 |
2023-08-12 |
Not clear |
| G V Obrocea, M E Morri. Comparison of changes evoked by GABA (gamma-aminobutyric acid) and anoxia in [K+]o, [Cl-]o, and [Na+]o in stratum pyramidale and stratum radiatum of the guinea pig hippocampus. Canadian journal of physiology and pharmacology. vol 78. issue 5. 2000-09-15. PMID:10841433. |
changes evoked by gaba or n2 in [k+]o, [cl-]o, [na+]o, and [tma+]o were recorded in the cell body and dendritic regions of the stratum pyramidale (sp) and stratum radiatum (sr), respectively, of pyramidal neurons in ca1 of guinea pig hippocampal slices. |
2000-09-15 |
2023-08-12 |
Not clear |
| Y Ueda, L J Willmor. Hippocampal gamma-aminobutyric acid transporter alterations following focal epileptogenesis induced in rat amygdala. Brain research bulletin. vol 52. issue 5. 2000-09-14. PMID:10922514. |
hippocampal gamma-aminobutyric acid transporter alterations following focal epileptogenesis induced in rat amygdala. |
2000-09-14 |
2023-08-12 |
rat |
| Y Ueda, L J Willmor. Hippocampal gamma-aminobutyric acid transporter alterations following focal epileptogenesis induced in rat amygdala. Brain research bulletin. vol 52. issue 5. 2000-09-14. PMID:10922514. |
to study the role of hippocampal gamma-aminobutyric acid (gaba) transporters in epileptogenesis, we induced chronic seizures by ferric cation injection into the rat amygdaloid body. |
2000-09-14 |
2023-08-12 |
rat |