| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U Kraushaar, P Jona. Efficacy and stability of quantal GABA release at a hippocampal interneuron-principal neuron synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 15. 2000-08-10. PMID:10908596. |
efficacy and stability of quantal gaba release at a hippocampal interneuron-principal neuron synapse. |
2000-08-10 |
2023-08-12 |
rat |
| I G Sil'ki. [Unified postsynaptic mechanism of plasticity in the striatum, neocortex, hippocampus, and cerebellum]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 86. issue 5. 2000-08-08. PMID:10885014. |
the unitary postsynaptic mechanism of plasticity in striatum, neocortex, hippocampus and cerebellum involves the ltp/ltd excitation as result of ampa and nmda receptor phosphorylation/dephosphorylation, while the ltp/ltd of inhibition is the result of the gaba receptor phosphorylation/dephosphorylation. |
2000-08-08 |
2023-08-12 |
Not clear |
| F Loup, H G Wieser, Y Yonekawa, A Aguzzi, J M Fritsch. Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884325. |
we have therefore analyzed subunit composition and distribution of the three major gaba(a) receptor subtypes immunohistochemically with subunit-specific antibodies (alpha1, alpha2, alpha3, beta2,3, and gamma2) in surgical specimens from tle patients with hippocampal sclerosis (n = 16). |
2000-08-03 |
2023-08-12 |
human |
| F Loup, H G Wieser, Y Yonekawa, A Aguzzi, J M Fritsch. Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 14. 2000-08-03. PMID:10884325. |
these results demonstrate unique subtype-specific expression of gaba(a) receptors in human hippocampus. |
2000-08-03 |
2023-08-12 |
human |
| C Redecker, H J Luhmann, G Hagemann, J M Fritschy, O W Witt. Differential downregulation of GABAA receptor subunits in widespread brain regions in the freeze-lesion model of focal cortical malformations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 13. 2000-07-26. PMID:10864962. |
interestingly, the downregulation of gaba(a) receptor subunits also involved the ipsilateral hippocampal formation, as well as restricted contralateral neocortical areas, indicating widespread disturbances in the neocortical and hippocampal network. |
2000-07-26 |
2023-08-12 |
rat |
| G Hoogland, J J Hens, M De Wit, C W van Veelen, A C van Huffelen, W H Gispen, P N de Graa. Glutamate and gamma-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients. Journal of neuroscience research. vol 60. issue 5. 2000-07-24. PMID:10820440. |
hippocampal synaptosomes from mts-associated tle patients, unlike those from t-associated tle patients, contained about 70% less glutamate and 55% less gaba than neocortical synaptosomes. |
2000-07-24 |
2023-08-12 |
human |
| M Higashima, K Ohno, H Kinoshita, Y Koshin. Involvement of GABA(A) and GABA(B) receptors in afterdischarge generation in rat hippocampal slices. Brain research. vol 865. issue 2. 2000-07-24. PMID:10821920. |
involvement of gaba(a) and gaba(b) receptors in afterdischarge generation in rat hippocampal slices. |
2000-07-24 |
2023-08-12 |
rat |
| M Higashima, K Ohno, H Kinoshita, Y Koshin. Involvement of GABA(A) and GABA(B) receptors in afterdischarge generation in rat hippocampal slices. Brain research. vol 865. issue 2. 2000-07-24. PMID:10821920. |
we therefore examined the pharmacological effects of selective agonists and antagonists of gaba(a) and gaba(b) receptors on ictal-like afterdischarges (ads) induced following repetitive high-frequency electrical stimulation in the ca1 region of rat hippocampal slices. |
2000-07-24 |
2023-08-12 |
rat |
| L Trabace, T Cassano, L Steardo, C Pietra, G Villetti, K M Kendrick, V Cuom. Biochemical and neurobehavioral profile of CHF2819, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease. The Journal of pharmacology and experimental therapeutics. vol 294. issue 1. 2000-07-24. PMID:10871311. |
furthermore, chf2819 induces a significant decrease in dopamine levels and a significant elevation of extracellular concentrations of 5-hydroxytryptamine, whereas it does not modify norepinephrine and gamma-aminobutyric acid levels in the hippocampus of young adult rats. |
2000-07-24 |
2023-08-12 |
rat |
| S Sagratella, S Marinell. Effects of some GABA and NMDA antagonists on a model of presynaptic hippocampal paired pulse inhibition. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 2. 2000-07-19. PMID:10800754. |
effects of some gaba and nmda antagonists on a model of presynaptic hippocampal paired pulse inhibition. |
2000-07-19 |
2023-08-12 |
rat |
| S Sagratella, S Marinell. Effects of some GABA and NMDA antagonists on a model of presynaptic hippocampal paired pulse inhibition. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 2. 2000-07-19. PMID:10800754. |
the effects of some nmda antagonists (7-chlorokynurenic acid and cgs 19755) and of the gaba antagonist penicillin were tested in a model of presynaptic short-term paired-pulse inhibition elicited in rat hippocampal slice with high (+ 2 mm) calcium solutions subjected to paired (15 ms)-pulse stimulation paradigm. |
2000-07-19 |
2023-08-12 |
rat |
| J Vautrin, D Maric, M Sukhareva, A E Schaffner, J L Barke. Surface-accessible GABA supports tonic and quantal synaptic transmission. Synapse (New York, N.Y.). vol 37. issue 1. 2000-07-17. PMID:10842350. |
using confocal microscopy and flow cytometry of embryonic rat hippocampal neurons, we found a gaba immunoreaction at the surface of live cell bodies and growth cones that coincided spatially and quantitatively with the binding of tetanus toxin fragment c (ttfc). |
2000-07-17 |
2023-08-12 |
rat |
| D F Covey, D Nathan, M Kalkbrenner, K R Nilsson, Y Hu, C F Zorumski, A S Ever. Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia. The Journal of pharmacology and experimental therapeutics. vol 293. issue 3. 2000-07-14. PMID:10869405. |
stereoselective actions of the compounds were evaluated in four different bioassays: 1) noncompetitive displacement of [(35)s]t-butylbicyclophosphorothionate from the picrotoxin site of gaba(a) receptors present in rat brain membrane preparations; 2) modulation of gaba currents in cultured rat hippocampal neurons; 3) loss of righting reflex in tadpoles; and 4) loss of righting reflex in mice. |
2000-07-14 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Taurine release modified by GABAergic agents in hippocampal slices from adult and developing mice. Amino acids. vol 18. issue 1. 2000-07-11. PMID:10794129. |
in order to characterize the possible regulation of taurine release by gabaergic terminals, the effects of several agonists and antagonists of gaba receptors on the basal and k+-stimulated release of [3h]taurine were investigated in hippocampal slices from adult (3-month-old) and developing (7-day-old) mice using a superfusion system. |
2000-07-11 |
2023-08-12 |
mouse |
| P Saransaari, S S Oj. Taurine release modified by GABAergic agents in hippocampal slices from adult and developing mice. Amino acids. vol 18. issue 1. 2000-07-11. PMID:10794129. |
the potentiation of taurine release by agents acting on the three types of gaba receptors in both adult and developing hippocampus further indicates the involvement of transporters operating in an outward direction. |
2000-07-11 |
2023-08-12 |
mouse |
| Q Zhou, C C Petersen, R A Nicol. Effects of reduced vesicular filling on synaptic transmission in rat hippocampal neurones. The Journal of physiology. vol 525 Pt 1. 2000-07-10. PMID:10811737. |
the consequence of reduced uptake of neurotransmitters into synaptic vesicles on synaptic transmission was examined in rat hippocampal slices and culture using bafilomycin a1 (baf), a potent and specific blocker of the vacuolar-type (v-type) atpase, which eliminates the driving force for the uptake of both glutamate and gaba into synaptic vesicles. |
2000-07-10 |
2023-08-12 |
rat |
| N del Olmo, J Bustamante, R M del Río, J M Solí. Taurine activates GABA(A) but not GABA(B) receptors in rat hippocampal CA1 area. Brain research. vol 864. issue 2. 2000-07-03. PMID:10802037. |
we investigated if taurine, an endogenous gaba analog, could mimic both hyperpolarizing and depolarizing gaba(a)-mediated responses as well as pre- and postsynaptic gaba(b)-mediated actions in the ca1 region of rat hippocampal slices. |
2000-07-03 |
2023-08-12 |
rat |
| M J Beckstead, J L Weiner, E I Eger, D H Gong, S J Mihi. Glycine and gamma-aminobutyric acid(A) receptor function is enhanced by inhaled drugs of abuse. Molecular pharmacology. vol 57. issue 6. 2000-06-22. PMID:10825391. |
tce and toluene, like ethanol, reversibly enhanced gamma-aminobutyric acid (gaba)(a) receptor-mediated synaptic currents in rat hippocampal slices. |
2000-06-22 |
2023-08-12 |
rat |
| S H Lee, S C Yang, J K Park, M W Jung, C J Le. Reduction of electrically evoked neural activity by ginseng saponin in rat hippocampal slices. Biological & pharmaceutical bulletin. vol 23. issue 4. 2000-06-21. PMID:10784418. |
the possible role of gamma-aminobutyric acid (gaba(a)) receptor in the suppressive action of ginseng saponins was tested using whole cell patch recording in acutely isolated hippocampal neurons. |
2000-06-21 |
2023-08-12 |
rat |
| W Xu, R Cormier, T Fu, D F Covey, K E Isenberg, C F Zorumski, S Menneric. Slow death of postnatal hippocampal neurons by GABA(A) receptor overactivation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 9. 2000-06-02. PMID:10777778. |
slow death of postnatal hippocampal neurons by gaba(a) receptor overactivation. |
2000-06-02 |
2023-08-12 |
Not clear |