| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U Thomet, R Baur, R Razet, R H Dodd, R Furtmüller, W Sieghart, E Sige. A novel positive allosteric modulator of the GABA(A) receptor: the action of (+)-ROD188. British journal of pharmacology. vol 131. issue 4. 2000-12-05. PMID:11030736. |
miniature inhibitory postsynaptic currents (mipsc) in cultures of rat hippocampal neurons, caused by spontaneous release of gaba showed a prolonged decay time in the presence of 30 microm (+)-rod188, indicating an enhanced synaptic inhibitory transmission. |
2000-12-05 |
2023-08-12 |
rat |
| J C Poncer, R A McKinney, B H Gahwiler, S M Thompso. Differential control of GABA release at synapses from distinct interneurons in rat hippocampus. The Journal of physiology. vol 528 Pt 1. 2000-11-30. PMID:11018111. |
differential control of gaba release at synapses from distinct interneurons in rat hippocampus. |
2000-11-30 |
2023-08-12 |
rat |
| J C Poncer, R A McKinney, B H Gahwiler, S M Thompso. Differential control of GABA release at synapses from distinct interneurons in rat hippocampus. The Journal of physiology. vol 528 Pt 1. 2000-11-30. PMID:11018111. |
paired recordings from monosynaptically connected ca3 interneurons and pyramidal cells of rat hippocampal slice cultures were used to compare the modulation of gaba release at synapses from distinct interneurons. |
2000-11-30 |
2023-08-12 |
rat |
| L Korhonen, U Sjöholm, N Takei, M A Kern, P Schirmacher, E Castrén, D Lindhol. Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons. The European journal of neuroscience. vol 12. issue 10. 2000-11-30. PMID:11029614. |
in contrast to calbindin d neurons, hgf did not significantly increase the number of neurons immunoreactive with the neurotransmitter gamma-aminobutyric acid (gaba) in the hippocampal cultures. |
2000-11-30 |
2023-08-12 |
rat |
| A Degroot, M B Paren. Increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal GABA receptor activation on spontaneous alternation. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040261. |
increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal gaba receptor activation on spontaneous alternation. |
2000-11-21 |
2023-08-12 |
rat |
| A Degroot, M B Paren. Increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal GABA receptor activation on spontaneous alternation. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040261. |
these findings indicate that increasing cholinergic levels in the hippocampus or entorhinal cortex is sufficient to reverse the impairing effects of septal gaba receptor activation and support the hypothesis that the impairing effects of septal gabaergic activity involve cholinergic processes in the hippocampus and the entorhinal cortex. |
2000-11-21 |
2023-08-12 |
rat |
| M R Vianna, M Alonso, H Viola, J Quevedo, F de Paris, M Furman, M L de Stein, J H Medina, I Izquierd. Role of hippocampal signaling pathways in long-term memory formation of a nonassociative learning task in the rat. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 5. 2000-11-21. PMID:11040265. |
the immediate posttraining bilateral infusion of cnqx (1 microg/side), an ampa/kainate glutamate receptor antagonist, or of muscimol (0.03 microg/side), a gaba(a) receptor agonist, into the ca1 region of the dorsal hippocampus impaired long-term memory of habituation. |
2000-11-21 |
2023-08-12 |
rat |
| A Köfalvi, B Sperlágh, T Zelles, E S Viz. Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation. The Journal of pharmacology and experimental therapeutics. vol 295. issue 2. 2000-11-21. PMID:11046076. |
long-lasting facilitation of 4-amino-n-[2,3-(3)h]butyric acid ([(3)h]gaba) release from rat hippocampal slices by nicotinic receptor activation. |
2000-11-21 |
2023-08-12 |
rat |
| A Köfalvi, B Sperlágh, T Zelles, E S Viz. Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation. The Journal of pharmacology and experimental therapeutics. vol 295. issue 2. 2000-11-21. PMID:11046076. |
in this study we explored the effect of the stimulation of nicotinic acetylcholine receptors located on interneurons by measuring 4-amino-n-[2,3-(3)h]butyric acid ([(3)h]gaba) release and monitoring [ca (2+)](i) in superfused hippocampal slices. |
2000-11-21 |
2023-08-12 |
rat |
| A Köfalvi, B Sperlágh, T Zelles, E S Viz. Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation. The Journal of pharmacology and experimental therapeutics. vol 295. issue 2. 2000-11-21. PMID:11046076. |
these findings indicate that the activation of alpha 7-type nicotinic receptors of hippocampal interneurons results in a long-lasting ability of these cells to respond to depolarization with an increased release of gaba mediated by the transporter system. |
2000-11-21 |
2023-08-12 |
rat |
| W Poelchen, W R Proctor, T V Dunwiddi. The in vitro ethanol sensitivity of hippocampal synaptic gamma-aminobutyric acid(A) responses differs in lines of mice and rats genetically selected for behavioral sensitivity or insensitivity to ethanol. The Journal of pharmacology and experimental therapeutics. vol 295. issue 2. 2000-11-21. PMID:11046113. |
the in vitro ethanol sensitivity of hippocampal synaptic gamma-aminobutyric acid(a) responses differs in lines of mice and rats genetically selected for behavioral sensitivity or insensitivity to ethanol. |
2000-11-21 |
2023-08-12 |
mouse |
| N O Dalb. GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974324. |
the present study examines the effect of tiagabine (a selective inhibitor of gaba transporter 1, gat-1), snap-5114 (a semi-selective inhibitor of rat gat-3/mouse gat4) and nnc 05-2045 (a non-selective gaba uptake inhibitor) in modulating gaba levels in the hippocampus and thalamus. |
2000-11-13 |
2023-08-12 |
mouse |
| N O Dalb. GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974324. |
tiagabine (30 microm, perfused through the microdialysis probe in halothane anaesthetized rats) increased gaba levels to (% basal+/-sem) 645+/-69 in the hippocampus and 409+/-61 in the thalamus. |
2000-11-13 |
2023-08-12 |
mouse |
| N O Dalb. GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974324. |
snap-5114 (100 microm) increased gaba levels in the thalamus (% basal+/-sem) to 247+/-27 but had no effect on hippocampal gaba-levels. |
2000-11-13 |
2023-08-12 |
mouse |
| N O Dalb. GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974324. |
nnc 05-2045 (100 microm) increased gaba levels both in the hippocampus (% basal+/-sem, 251+/-51) and in the thalamus (298+/-27). |
2000-11-13 |
2023-08-12 |
mouse |
| D A Richards, L A Morrone, N G Bower. Hippocampal extracellular amino acids and EEG spectral analysis in a genetic rat model of absence epilepsy. Neuropharmacology. vol 39. issue 12. 2000-11-13. PMID:10974327. |
we report significantly higher levels of basal extracellular glutamate within the hippocampus of gaers, together with transient increases in citrulline and glycine following aggravation of the absence seizures with the gaba(b) agonist, (-)baclofen. |
2000-11-13 |
2023-08-12 |
rat |
| O C Snea. Evidence for a G protein-coupled gamma-hydroxybutyric acid receptor. Journal of neurochemistry. vol 75. issue 5. 2000-11-09. PMID:11032888. |
the ghb-induced effect was blocked by ghb antagonists but not by gaba(b)r antagonists and was seen only in cortex and hippocampus. |
2000-11-09 |
2023-08-12 |
rat |
| K Zilles, J Wu, W E Crusio, H Schwegle. Water maze and radial maze learning and the density of binding sites of glutamate, GABA, and serotonin receptors in the hippocampus of inbred mouse strains. Hippocampus. vol 10. issue 3. 2000-11-07. PMID:10902891. |
water maze and radial maze learning and the density of binding sites of glutamate, gaba, and serotonin receptors in the hippocampus of inbred mouse strains. |
2000-11-07 |
2023-08-12 |
mouse |
| K Zilles, J Wu, W E Crusio, H Schwegle. Water maze and radial maze learning and the density of binding sites of glutamate, GABA, and serotonin receptors in the hippocampus of inbred mouse strains. Hippocampus. vol 10. issue 3. 2000-11-07. PMID:10902891. |
correlations between the densities of ionotropic glutamate, gaba(a), and serotonin binding sites in the hippocampus of seven inbred mouse strains and strain-specific learning capacities in two types of maze were studied. |
2000-11-07 |
2023-08-12 |
mouse |
| F Bernal, N Andrés, D Samuel, L Kerkerian-LeGoff, N Mah. Age-related resistance to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid-induced hippocampal lesion. Hippocampus. vol 10. issue 3. 2000-11-07. PMID:10902899. |
finally, at ampa 2.7 mm, no significant changes in the density of hippocampal parvalbumin- or calbindin-immunoreactive neurons or in choline acetyltransferase, glutamate uptake, or gaba uptake activities were found in 15-month-old animals, whereas significant reductions in parvalbumin (-76%) and calbindin (-32%) immunostaining and in gaba uptake (-27%) were observed in 3-month-old animals compared to the respective sham-operated or control animals. |
2000-11-07 |
2023-08-12 |
rat |