| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R S Sloviter, L Ali-Akbarian, K D Horvath, K A Menken. Substance P receptor expression by inhibitory interneurons of the rat hippocampus: enhanced detection using improved immunocytochemical methods for the preservation and colocalization of GABA and other neuronal markers. The Journal of comparative neurology. vol 430. issue 3. 2001-05-03. PMID:11169468. |
one issue was the longstanding inability to detect gamma-aminobutyric acid (gaba) in the somata of several hippocampal interneuron subpopulations, which has prevented the unequivocal identification of all hippocampal interneurons as gaba neurons. |
2001-05-03 |
2023-08-12 |
rat |
| R S Sloviter, L Ali-Akbarian, K D Horvath, K A Menken. Substance P receptor expression by inhibitory interneurons of the rat hippocampus: enhanced detection using improved immunocytochemical methods for the preservation and colocalization of GABA and other neuronal markers. The Journal of comparative neurology. vol 430. issue 3. 2001-05-03. PMID:11169468. |
using newly developed methods designed to copreserve and colocalize gaba and polypeptide immunoreactivities with increased sensitivity, the authors report that virtually all hippocampal interneuron somata that are immunoreactive for parvalbumin (pv), calbindin, calretinin, somatostatin (ss), neuropeptide y, cholecystokinin, and vasoactive intestinal peptide exhibited clearly detectable, somal, gaba-like immunoreactivity (li). |
2001-05-03 |
2023-08-12 |
rat |
| T Inoue, F Wang, A Moriguchi, K Shirakawa, N Matsuoka, T Got. FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices. Brain research. vol 892. issue 1. 2001-05-03. PMID:11172755. |
on the other hands, fk960 had no effects on the release of neurotransmitters such as acetylcholine, 5-ht, d-aspartate or gaba from hippocampal slices. |
2001-05-03 |
2023-08-12 |
rat |
| S Berretta, D W Munno, F M Bene. Amygdalar activation alters the hippocampal GABA system: "partial" modelling for postmortem changes in schizophrenia. The Journal of comparative neurology. vol 431. issue 2. 2001-04-26. PMID:11169995. |
in the hippocampus, compelling evidence suggests that a disruption of gaba neurotransmission is present mainly in sectors ca4, ca3, and ca2. |
2001-04-26 |
2023-08-12 |
rat |
| R F Squires, E Saederu. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochemical research. vol 25. issue 12. 2001-04-19. PMID:11152388. |
chronic administration of clozapine to rats was reported to significantly reduce the numbers of [3h]mus binding sites in temporal cortex and hippocampus which may be due to selective blockade of gaba(a) receptors on gabaergic interneurons that make synaptic contact with pyramidal cells. |
2001-04-19 |
2023-08-12 |
rat |
| R F Squires, E Saederu. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochemical research. vol 25. issue 12. 2001-04-19. PMID:11152388. |
the gaba(a) receptor blocker bicuculline at 10 nm, but not 10 microm, was reported to increase the amplitude of slow oscillations (< or =1 hz) in rat hippocampal slices. |
2001-04-19 |
2023-08-12 |
rat |
| B Hassel, E Taubøll, L Gjersta. Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. Epilepsy research. vol 43. issue 2. 2001-04-19. PMID:11164704. |
chronic lamotrigine treatment increases rat hippocampal gaba shunt activity and elevates cerebral taurine levels. |
2001-04-19 |
2023-08-12 |
rat |
| B Hassel, E Taubøll, L Gjersta. Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. Epilepsy research. vol 43. issue 2. 2001-04-19. PMID:11164704. |
the hippocampal level of gaba increased 25%, and the activities of glutamate decarboxylase and succinic semialdehyde/gaba transaminase increased 12 and 21% (p< 0.05), respectively, indicating increased gaba turnover. |
2001-04-19 |
2023-08-12 |
rat |
| R D Traub, R Bibbig, A Piechotta, R Draguhn, D Schmit. Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro. Journal of neurophysiology. vol 85. issue 3. 2001-04-19. PMID:11247993. |
hippocampal slices bathed in 4-aminopyridine (4-ap, < or =200 microm) exhibit 1) spontaneous large inhibitory postsynaptic potentials (ipsps) in pyramidal cells, which occur without the necessity of fast glutamatergic receptors, and which hence are presumed to arise from coordinated firing in populations of interneurons; 2) spikes of variable amplitude, presumed to be of antidromic origin, in some pyramidal cells during the large ipsp; 3) bursts of action potentials in selected populations of interneurons, occurring independently of fast glutamatergic and of gaba(a) receptors. |
2001-04-19 |
2023-08-12 |
Not clear |
| D Bai, G Zhu, P Pennefather, M F Jackson, J F MacDonald, B A Orse. Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Molecular pharmacology. vol 59. issue 4. 2001-04-19. PMID:11259626. |
distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(a) receptors in hippocampal neurons. |
2001-04-19 |
2023-08-12 |
rat |
| D Bai, G Zhu, P Pennefather, M F Jackson, J F MacDonald, B A Orse. Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Molecular pharmacology. vol 59. issue 4. 2001-04-19. PMID:11259626. |
here we demonstrate that gaba(a) receptors mediating the tonic current in hippocampal neurons exhibit functional and pharmacological properties different from those of quantal synaptic currents. |
2001-04-19 |
2023-08-12 |
rat |
| V Gundersen, F Fonnum, O P Ottersen, J Storm-Mathise. Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 21. issue 1. 2001-04-05. PMID:11149667. |
postembedding immunocytochemistry was used to localize aspartate, glutamate, gamma-aminobutyric acid (gaba), and glutamine in hippocampus and striatum during normo- and hypoglycemia in rat. |
2001-04-05 |
2023-08-12 |
rat |
| R Cossart, R Tyzio, C Dinocourt, M Esclapez, J C Hirsch, Y Ben-Ari, C Bernar. Presynaptic kainate receptors that enhance the release of GABA on CA1 hippocampal interneurons. Neuron. vol 29. issue 2. 2001-04-05. PMID:11239438. |
presynaptic kainate receptors that enhance the release of gaba on ca1 hippocampal interneurons. |
2001-04-05 |
2023-08-12 |
Not clear |
| E B Arushunian, E V Beĭe. [The role for the hippocampus in the biorhythmical behavior]. Uspekhi fiziologicheskikh nauk. vol 32. issue 1. 2001-03-29. PMID:11234437. |
psychotropic drugs (anxiolytics and antidepressants) by means of intensified of hippocampal inhibitory mechanisms (previously gaba and 5-ht) are stabilized of biorhythms what determined their specific anxiolytic and antidepressant effects. |
2001-03-29 |
2023-08-12 |
Not clear |
| Y Ueda, T Doi, J Tokumaru, H Yokoyama, A Nakajima, Y Mitsuyama, H Ohya-Nishiguchi, H Kamada, L J Willmor. Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158261. |
we used northern and western blotting to measure the quantity of glutamate and gaba transporters mrna and their proteins within the hippocampal tissue of rats with epileptogenesis. |
2001-03-15 |
2023-08-12 |
rat |
| K Jensen, M S Jensen, B E Bonefeld, J D Lamber. Developmental increase in asynchronous GABA release in cultured hippocampal neurons. Neuroscience. vol 101. issue 3. 2001-03-01. PMID:11113307. |
developmental increase in asynchronous gaba release in cultured hippocampal neurons. |
2001-03-01 |
2023-08-12 |
Not clear |
| H E Edwards, T Epps, P L Carlen, N J MacLusk. Progestin receptors mediate progesterone suppression of epileptiform activity in tetanized hippocampal slices in vitro. Neuroscience. vol 101. issue 4. 2001-03-01. PMID:11113338. |
hippocampal slices were superfused in vitro with one of the following treatments: progesterone with or without ru486 (a progesterone receptor antagonist); allopregnanolone (a progesterone metabolite that potentiates gaba action at gaba(a) receptors); ru5020 (a high-affinity progesterone receptor agonist); or cholesterol (control). |
2001-03-01 |
2023-08-12 |
rat |
| L S Overstreet, M V Jones, G L Westbroo. Slow desensitization regulates the availability of synaptic GABA(A) receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050111. |
we report here that low concentrations of gaba reduce ipscs in hippocampal neurons by preferentially desensitizing rather than opening gaba(a) channels. |
2001-02-22 |
2023-08-12 |
Not clear |
| J T Kittler, P Delmas, J N Jovanovic, D A Brown, T G Smart, S J Mos. Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050117. |
here we show that constitutive internalization of gaba(a) receptors in hippocampal neurons and recombinant receptors expressed in a293 cells is mediated by clathrin-dependent endocytosis. |
2001-02-22 |
2023-08-12 |
Not clear |
| J T Kittler, P Delmas, J N Jovanovic, D A Brown, T G Smart, S J Mos. Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050117. |
gaba(a) receptors also colocalize with ap2 in cultured hippocampal neurons. |
2001-02-22 |
2023-08-12 |
Not clear |