| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Marty, R Wehrlé, C Sotel. Neuronal activity and brain-derived neurotrophic factor regulate the density of inhibitory synapses in organotypic slice cultures of postnatal hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050130. |
hippocampal interneurons inhibit pyramidal neurons through the release of the neurotransmitter gaba. |
2001-02-22 |
2023-08-12 |
rat |
| S Marty, R Wehrlé, C Sotel. Neuronal activity and brain-derived neurotrophic factor regulate the density of inhibitory synapses in organotypic slice cultures of postnatal hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050130. |
in hippocampal slices cultured for 13 d in the presence of the gaba(a) receptor antagonist bicuculline, the density of glutamic acid decarboxylase (gad) 65-immunoreactive terminals was increased in the ca1 area when compared with control slices. |
2001-02-22 |
2023-08-12 |
rat |
| M Alreja, M Wu, W Liu, J B Atkins, C Leranth, M Shanabroug. Muscarinic tone sustains impulse flow in the septohippocampal GABA but not cholinergic pathway: implications for learning and memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 21. 2001-02-22. PMID:11050132. |
an additional, possibly more important mechanism may be the concomitant decrease in septohippocampal gaba release and a subsequent disruption in disinhibitory mechanisms in the hippocampus. |
2001-02-22 |
2023-08-12 |
rat |
| A Rao, E M Cha, A M Crai. Mismatched appositions of presynaptic and postsynaptic components in isolated hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 22. 2001-02-22. PMID:11069941. |
to determine whether presynaptic input is necessary for postsynaptic differentiation, we isolated hippocampal neurons in microisland culture and thus deprived pyramidal cells of gaba input and gabaergic neurons of glutamate input. |
2001-02-22 |
2023-08-12 |
Not clear |
| K Shimono, F Brucher, R Granger, G Lynch, M Taketan. Origins and distribution of cholinergically induced beta rhythms in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 22. 2001-02-22. PMID:11069954. |
it is concluded that cholinergically driven beta rhythms arise independently in hippocampal subfields from oscillatory circuits involving (1) bursts of pyramidal cell discharges, (2) activation of a subset of feedback interneurons that project apically, and (3) production of a gaba(a)-mediated hyperpolarization in the outer portions of the apical dendrites of pyramidal neurons. |
2001-02-22 |
2023-08-12 |
Not clear |
| A Wainwright, D J Sirinathsinghji, K R Olive. Expression of GABA(A) receptor alpha5 subunit-like immunoreactivity in human hippocampus. Brain research. Molecular brain research. vol 80. issue 2. 2001-02-15. PMID:11038255. |
expression of gaba(a) receptor alpha5 subunit-like immunoreactivity in human hippocampus. |
2001-02-15 |
2023-08-12 |
human |
| M Monda, A Viggiano, V De Luc. Administration of muscimol into the posterior hypothalamus reduces hyperthermia induced by hippocampal neostigmine injection. Brain research. vol 887. issue 2. 2001-02-15. PMID:11134624. |
these variables were measured for 40 min before (baseline values) and 40 min after an injection of neostigmine (5 x 10(-7) mol in 1 microl of saline) into the hippocampus and a bilateral administration of a gaba(a)-agonist, muscimol (28 ng in 0.5 microl of saline, per side) into the posterior hypothalamus. |
2001-02-15 |
2023-08-12 |
rat |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
in mg(2+)-free solution, gaba(a)r antagonists elicited spfps in nearly all slices of p2 and older neocortex and p0 and older hippocampus. |
2001-02-08 |
2023-08-12 |
mouse |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
mg(2+)-free solution alone induced spontaneous events in the majority of p2 and older slices from both regions; addition of gaba(a)r antagonists caused a dramatic increase in the mean amplitude, but not frequency, of these events in the hippocampus and in their mean frequency, but not amplitude, in the neocortex. |
2001-02-08 |
2023-08-12 |
mouse |
| J E Wells, J T Porter, A Agmo. GABAergic inhibition suppresses paroxysmal network activity in the neonatal rodent hippocampus and neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102490. |
in the hippocampus, gaba(a)r agonists suppressed amplitudes, but not frequency, of spfps, whereas glutamate antagonists suppressed frequency but not amplitudes. |
2001-02-08 |
2023-08-12 |
mouse |
| T Sooksawate, M A Simmond. Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones. Neuropharmacology. vol 40. issue 2. 2001-02-08. PMID:11114396. |
effects of membrane cholesterol on the sensitivity of the gaba(a) receptor to gaba in acutely dissociated rat hippocampal neurones. |
2001-02-08 |
2023-08-12 |
rat |
| T Sooksawate, M A Simmond. Effects of membrane cholesterol on the sensitivity of the GABA(A) receptor to GABA in acutely dissociated rat hippocampal neurones. Neuropharmacology. vol 40. issue 2. 2001-02-08. PMID:11114396. |
the effects of membrane cholesterol on the gaba(a) receptor were investigated in acutely dissociated rat hippocampal neurones, using the whole-cell patch clamp technique. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
heterogeneity of hippocampal gaba(a) receptors: regulation by corticosterone. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
cort also alters gaba-mediated inhibitory neurotransmission, so the gaba(a) receptor system may also contribute to dendritic remodeling and other stress-related changes in hippocampal function. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
a previous study indicated that chronic cort treatment produces complex changes in gaba(a) receptor subunit mrna levels, so we hypothesized that cort alters the pharmacological properties of hippocampal gaba(a) receptors. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
we found striking regional differences in the modulation of [(35)s]tbps binding, particularly between strata radiatum and strata oriens, suggesting a functional heterogeneity among hippocampal gaba(a) receptors even within the apical versus basal dendrites of pyramidal neurons. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
furthermore, we found that cort treatment decreased the negative modulation of hippocampal [(35)s]tbps binding by both gaba and thdoc and increased the enhancement of [(3)h]flunitrazepam binding by gaba and thdoc in the dentate gyrus. |
2001-02-08 |
2023-08-12 |
rat |
| M Orchinik, S S Carroll, Y H Li, B S McEwen, N G Weilan. Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 1. 2001-02-08. PMID:11150350. |
together, these data suggest that prolonged exposure to stress levels of corticosteroids may alter hippocampal inhibitory tone by regulating the pharmacological properties of gaba(a) receptors in discrete dendritic subfields. |
2001-02-08 |
2023-08-12 |
rat |
| S S Smith, F C Hsu, X Li, C A Frye, D S Faber, R S Markowit. Oestrogen effects in olivo-cerebellar and hippocampal circuits. Novartis Foundation symposium. vol 230. 2001-01-25. PMID:10965507. |
this effect was correlated with a decrease in decay time of tetrodotoxin-resistant miniature inhibitory postsynaptic currents (mipscs) recorded from pyramidal cells in ca1 hippocampus, an effect which would tend to reduce total gaba inhibition. |
2001-01-25 |
2023-08-12 |
Not clear |
| G Y Ng, S Bertrand, R Sullivan, N Ethier, J Wang, J Yergey, M Belley, L Trimble, K Bateman, L Alder, A Smith, R McKernan, K Metters, G P O'Neill, J C Lacaille, T E Héber. Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. Molecular pharmacology. vol 59. issue 1. 2001-01-25. PMID:11125035. |
gamma-aminobutyric acid type b receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action. |
2001-01-25 |
2023-08-12 |
human |