| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Ueda, M Aikawa, A Ishizuya-Oka, S Yamaoka, N Koibuchi, K Yoshimot. Age-related dopamine deficiency in the mesostriatal dopamine system of zitter mutant rats: regional fiber vulnerability in the striatum and the olfactory tubercle. Neuroscience. vol 95. issue 2. 2000-02-29. PMID:10658618. |
age-related dopamine deficiency in the mesostriatal dopamine system of zitter mutant rats: regional fiber vulnerability in the striatum and the olfactory tubercle. |
2000-02-29 |
2023-08-12 |
rat |
| M Laruelle, A Abi-Dargha. Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies. Journal of psychopharmacology (Oxford, England). vol 13. issue 4. 2000-02-18. PMID:10667612. |
following a brief overview of these new brain imaging techniques, the main results derived with this method in patients with schizophrenia are described: (1) amphetamine-induced dopamine release is elevated in patients with schizophrenia, supporting the idea that schizophrenia is associated with dysregulation of dopamine transmission; (2) following amphetamine, hyperactivity of dopamine transmission is associated with activation of psychotic symptomatology; (3) this dysregulation of dopamine release is not a long-term consequence of previous neuroleptic treatment, and is detected in never-medicated patients experiencing a first episode of the illness; and (4) in contrast, this exaggerated response of the dopamine system to amphetamine exposure is not detected in patients studied during a period of illness stabilization, suggesting that the hyperdopaminergic state associated with schizophrenia fluctuates over time. |
2000-02-18 |
2023-08-12 |
human |
| J Svennilson, A Aperi. Dopamine in the developing kidney. The International journal of developmental biology. vol 43. issue 5. 1999-12-21. PMID:10535321. |
here, we discuss the age-dependent distribution and some functional aspects of several parts of the renal dopamine system (dopamine, aadc, comt, d1 receptor, and darpp-32) during renal morphogenesis. |
1999-12-21 |
2023-08-12 |
Not clear |
| R G Pett. Prolactin and antipsychotic medications: mechanism of action. Schizophrenia research. vol 35 Suppl. 1999-07-21. PMID:10190227. |
these new antipsychotics appear to spare dopamine blockade within the brain's tubero-infundibular tract, a dopamine pathway that also controls prolactin secretion. |
1999-07-21 |
2023-08-12 |
Not clear |
| W P Melega, G Lacan, D C Harvey, S C Huang, M E Phelp. Dizocilpine and reduced body temperature do not prevent methamphetamine-induced neurotoxicity in the vervet monkey: [11C]WIN 35,428 - positron emission tomography studies. Neuroscience letters. vol 258. issue 1. 1999-05-18. PMID:9876041. |
[11c]win 35,428 (win), a cocaine analog that binds to the dopamine transporter (dat), and positron emission tomography (pet) were used to evaluate the potential neuroprotective effects of dizocilpine (mk-801) on methamphetamine (meamp) induced neurotoxicity in the striatal dopamine system of the vervet monkey. |
1999-05-18 |
2023-08-12 |
human |
| G R Hanson, K A Keef. Dopamine D-1 regulation of caudate neurotensin mRNA in the presence or absence of the nigrostriatal dopamine pathway. Brain research. Molecular brain research. vol 66. issue 1-2. 1999-05-13. PMID:10095083. |
dopamine d-1 regulation of caudate neurotensin mrna in the presence or absence of the nigrostriatal dopamine pathway. |
1999-05-13 |
2023-08-12 |
Not clear |
| P Kehoe, W J Shoemaker, C Arons, L Triano, G Sures. Repeated isolation stress in the neonatal rat: relation to brain dopamine systems in the 10-day-old rat. Behavioral neuroscience. vol 112. issue 6. 1999-04-30. PMID:9926829. |
experiment 2 produced significant evidence of enhanced behavioral activation after the isolation paradigm and indicated that brain regions innervated by the mesolimbic dopamine system, septum, and hypothalamus display increased dopamine turnover and that the nigrostriatal pathway is less active. |
1999-04-30 |
2023-08-12 |
rat |
| M Melis, G L Gessa, M Dian. Clozapine does activate nigrostriatal dopamine neurons in unanesthetized rats. European journal of pharmacology. vol 363. issue 2-3. 1999-03-25. PMID:9881580. |
these results indicate that acute clozapine activates nigrostriatal dopamine cells in non-anaesthetised rats and cast doubts about a direct link between the lack of significant extrapyramidal side-effects and the selectivity of atypical neuroleptics, such as clozapine, for the mesolimbic dopamine system. |
1999-03-25 |
2023-08-12 |
rat |
| C Vadasz, I Sziraki, M Sasvari, P Kabai, L R Murthy, M Saito, I Laszlovszk. Analysis of the mesotelencephalic dopamine system by quantitative-trait locus introgression. Neurochemical research. vol 23. issue 11. 1999-03-08. PMID:9814544. |
for the analysis of the genetically determined role of dopamine function and th in behavior and in the regulatory mechanisms of the mesotelencephalic dopamine system we devised a novel genetic strategy (vadasz; mouse genome 88:16-18; 1990). |
1999-03-08 |
2023-08-12 |
mouse |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine d1 and d2 receptor-selective agonists: relevance to cocaine sensitization. |
1999-02-25 |
2023-08-12 |
rat |
| D Ebert, M Berge. Neurobiological similarities in antidepressant sleep deprivation and psychostimulant use: a psychostimulant theory of antidepressant sleep deprivation. Psychopharmacology. vol 140. issue 1. 1999-02-25. PMID:9862396. |
most antidepressant pharmacotherapies change the reactivity of the dopamine system, and a decrease of presynaptic dopamine or postsynaptic availability can induce depression. |
1999-02-25 |
2023-08-12 |
human |
| R Grondin, D M Gas. Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease. Journal of neurology. vol 245. issue 11 Suppl 3. 1999-01-22. PMID:9808338. |
in addition to its effects on cultured fetal midbrain dopamine neurons, gdnf promotes recovery of the injured nigrostriatal dopamine system and improves motor functions in rodent and nonhuman primate models of parkinson's disease. |
1999-01-22 |
2023-08-12 |
monkey |
| R R Holson, R A Gazzara, B Goug. Declines in stimulated striatal dopamine release over the first 32 h following microdialysis probe insertion: generalization across releasing mechanisms. Brain research. vol 808. issue 2. 1998-12-11. PMID:9767162. |
we conclude that there is a general decline over time post-probe implantation in the ability of the striatal dopamine system to release dopamine, and perhaps to increase dopamine synthesis, in response to pharmacological challenges. |
1998-12-11 |
2023-08-12 |
rat |
| R Iu Il'iuchenok, N I Dubrovina, E K Podgornai. [The mechanisms of the emotiogenic regulation of memory]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 9. 1998-12-04. PMID:9817000. |
the gaba system is shown to enter the mechanism that controls the activity of dopamine system--dopamine release from the terminals of the nigrostriatal and mesolimbic dopaminergic systems is stimulated. |
1998-12-04 |
2023-08-12 |
mouse |
| D W Self, E J Nestle. Relapse to drug-seeking: neural and molecular mechanisms. Drug and alcohol dependence. vol 51. issue 1-2. 1998-11-12. PMID:9716929. |
considerable evidence points to the mesolimbic dopamine system, and more specifically to activation of d2-like dopamine receptors in the nucleus accumbens, as a crucial neural substrate utilized by various stimuli that induce relapse. |
1998-11-12 |
2023-08-12 |
Not clear |
| J M Wilson, S Sanyal, H H Van To. Dopamine D2 and D4 receptor ligands: relation to antipsychotic action. European journal of pharmacology. vol 351. issue 3. 1998-10-29. PMID:9721018. |
since the discovery that the antipsychotic action of phenothiazines was mediated by dopamine d2 receptors, the dopamine system has been scrutinized for schizophrenia related abnormalities. |
1998-10-29 |
2023-08-12 |
Not clear |
| W Gong, D B Neill, J B Justic. GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661258. |
however, the effect of gaba on the mesopallidal dopamine system's response to locally applied cocaine may be complicated by actions of cocaine other than dopamine uptake inhibition. |
1998-09-24 |
2023-08-12 |
rat |
| B Gronier, K Rasmusse. Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat. British journal of pharmacology. vol 124. issue 3. 1998-09-16. PMID:9647468. |
these cholinoceptors would be able to influence the activity of the midbrain dopamine system greatly and may play a role in, and/or be a therapeutic target for, brain disorders in which dopamine is involved (e.g., parkinson's disease, drug addiction and schizophrenia). |
1998-09-16 |
2023-08-12 |
rat |
| M Jabe. [Dopamine control of neuroendocrine functions. New findings based on the study of transgenic animals]. Annales d'endocrinologie. vol 58. issue 6. 1998-09-01. PMID:9686001. |
here we summarize the main findings obtained with these transgenic animals carrying these "genetic defects" leading to a better understanding of the relative contribution of each of the corresponding gene product regarding locomotor activity, regulation of the expression of peptides under the dopamine control, responses to various drugs targeting the dopamine system and control of pituitary function. |
1998-09-01 |
2023-08-12 |
mouse |
| R R Gainetdinov, S R Jones, F Fumagalli, R M Wightman, M G Caro. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain research. Brain research reviews. vol 26. issue 2-3. 1998-08-28. PMID:9651511. |
re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. |
1998-08-28 |
2023-08-12 |
mouse |