| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asa Rosin, Ian Kitchen, Jeanette Georgiev. Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834892. |
both cocaine and ethanol increase the extracellular dopamine concentration in the nucleus accumbens, a terminal region in the mesolimbic dopamine pathway. |
2003-09-08 |
2023-08-12 |
human |
| S Ahn, A G Phillip. Independent modulation of basal and feeding-evoked dopamine efflux in the nucleus accumbens and medial prefrontal cortex by the central and basolateral amygdalar nuclei in the rat. Neuroscience. vol 116. issue 1. 2003-06-24. PMID:12535961. |
overall, these findings indicate that the central and basolateral independently modulate dopamine transmission in both terminal regions of the mesocorticolimbic dopamine system. |
2003-06-24 |
2023-08-12 |
rat |
| Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the data suggest that the mesopallidal, mesoaccumbens, and nigrostriatal dopamine systems are more sensitive to the effects of ethanol than the nigropallidal dopamine system. |
2003-06-11 |
2023-08-12 |
rat |
| Rebecca J Ralph-Williams, Martin P Paulus, Xiaoxi Zhuang, Rene Hen, Mark A Geye. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biological psychiatry. vol 53. issue 4. 2003-05-07. PMID:12586455. |
dopamine transporter (dat) knockdown (kd) mice, with approximately 90% loss of expression of the dat, allow for the examination of the behavioral consequences of a chronically dysregulated dopamine system. |
2003-05-07 |
2023-08-12 |
mouse |
| G D Phillips, E Setzu, A Vugler, P K Hitchcot. An immunohistochemical examination of the effects of sensitisation on the mesotelencephalic dopaminergic response to d-amphetamine. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617978. |
the dopaminergic response to d-amphetamine with or without prior repeated experience with the drug was investigated immunohistochemically in key target regions of the mesotelencephalic dopamine system using antibodies raised against glutaraldehyde-conjugated dopamine. |
2003-05-05 |
2023-08-12 |
rat |
| G D Phillips, E Setzu, A Vugler, P K Hitchcot. Immunohistochemical assessment of mesotelencephalic dopamine activity during the acquisition and expression of Pavlovian versus instrumental behaviours. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617979. |
dopaminergic activity during pavlovian or instrumental learning in key target regions of the mesotelencephalic dopamine system was investigated immunohistochemically using antibodies raised against glutaraldehyde-conjugated dopamine. |
2003-05-05 |
2023-08-12 |
Not clear |
| G D Phillips, E Setzu, A Vugler, P K Hitchcot. Immunohistochemical assessment of mesotelencephalic dopamine activity during the acquisition and expression of Pavlovian versus instrumental behaviours. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617979. |
thus, the acquisition, but not expression of pavlovian associations activated dopamine within several key target regions of the mesotelencephalic dopamine system, and preferentially within the shell rather than core of the nucleus accumbens. |
2003-05-05 |
2023-08-12 |
Not clear |
| Phil Ok Koh, Clare Bergson, Ashiwel S Undie, Patricia S Goldman-Rakic, Michael S Lido. Up-regulation of the D1 dopamine receptor-interacting protein, calcyon, in patients with schizophrenia. Archives of general psychiatry. vol 60. issue 3. 2003-04-03. PMID:12622665. |
the dopamine hypothesis remains a prominent influence on research into the pathogenesis of schizophrenia, yet the presence of consistent schizophrenia-linked abnormalities in the presynaptic components of the dopamine system or in dopamine receptors still remains a matter of debate. |
2003-04-03 |
2023-08-12 |
Not clear |
| Elizabeth M Byrnes, Beth A Rigero, Robert S Bridge. Dopamine antagonists during parturition disrupt maternal care and the retention of maternal behavior in rats. Pharmacology, biochemistry, and behavior. vol 73. issue 4. 2003-03-04. PMID:12213533. |
to determine whether the dopamine system is involved in the retention of maternal behavior, females were continuously infused with dopamine antagonists during the periparturitional period and then allowed either a brief interaction period with pups (3 h) or no interaction with pups (pups removed as they were born). |
2003-03-04 |
2023-08-12 |
rat |
| Isabel Schwienbacher, Markus Fendt, Wolfgang Hauber, Michael Koc. Dopamine D1 receptors and adenosine A1 receptors in the rat nucleus accumbens regulate motor activity but not prepulse inhibition. European journal of pharmacology. vol 444. issue 3. 2003-02-11. PMID:12063076. |
these findings demonstrate that adenosine a(1) and dopamine d(1) receptors are involved in the regulation of locomotor activity mediated by the mesoaccumbal dopamine system. |
2003-02-11 |
2023-08-12 |
rat |
| Nathaniel D Daw, Sham Kakade, Peter Daya. Opponent interactions between serotonin and dopamine. Neural networks : the official journal of the International Neural Network Society. vol 15. issue 4-6. 2003-02-11. PMID:12371515. |
in the light of the temporal difference model of the involvement of the dopamine system in reward learning, we consider three aspects of motivational opponency involving dopamine and serotonin. |
2003-02-11 |
2023-08-12 |
Not clear |
| R Sánchez-Pernaute, A L Brownell, O Isacso. Functional imaging of the dopamine system: in vivo evaluation of dopamine deficiency and restoration. Neurotoxicology. vol 23. issue 4-5. 2002-12-16. PMID:12428719. |
functional imaging of the dopamine system: in vivo evaluation of dopamine deficiency and restoration. |
2002-12-16 |
2023-08-12 |
Not clear |
| A Weisel-Eichler, F Libersa. Are monoaminergic systems involved in the lethargy induced by a parasitoid wasp in the cockroach prey? Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 188. issue 4. 2002-11-15. PMID:12012102. |
we treated cockroaches with antagonists to dopamine and octopamine receptors, and found that the dopamine system is required for normal escape response. |
2002-11-15 |
2023-08-12 |
Not clear |
| C C Stanley-Cary, C Harris, M T Martin-Iverso. Differing effects of the cannabinoid agonist, CP 55,940, in an alcohol or Tween 80 solvent, on prepulse inhibition of the acoustic startle reflex in the rat. Behavioural pharmacology. vol 13. issue 1. 2002-09-30. PMID:11990716. |
it has been suggested that cannabinoid agonists increase dopamine (da) transmission in the mesolimbic dopamine system. |
2002-09-30 |
2023-08-12 |
rat |
| G A Metz, I Q Whisha. Drug-induced rotation intensity in unilateral dopamine-depleted rats is not correlated with end point or qualitative measures of forelimb or hindlimb motor performance. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983318. |
while the number of rotations under apomorphine, l-dopa and amphetamine is related to the extent of dopamine depletion after unilateral 6-hydroxydopamine lesion of the nigrostriatal dopamine system, the relationship of the intensity of rotational behavior to the degree of impairment in motor behavior is unclear. |
2002-08-13 |
2023-08-12 |
rat |
| Wayne A Cass, Michael E Harned, Sherry L Baile. Enhanced effects of 6-hydroxydopamine on evoked overflow of striatal dopamine in aged rats. Brain research. vol 938. issue 1-2. 2002-08-08. PMID:12031532. |
although 6-hydroxydopamine lesioning of the nigrostriatal dopamine system is a common method for producing animal models of dopamine neuron degeneration, there have been relatively few studies that have examined the effects of 6-hydroxydopamine on the dopamine systems of aged animals. |
2002-08-08 |
2023-08-12 |
rat |
| Martina Ballmaier, Michele Zoli, Giuseppina Leo, Luigi Francesco Agnati, PierFranco Span. Preferential alterations in the mesolimbic dopamine pathway of heterozygous reeler mice: an emerging animal-based model of schizophrenia. The European journal of neuroscience. vol 15. issue 7. 2002-06-21. PMID:11982630. |
as brain mesolimbic dopamine pathways have been proposed to be associated with the pathophysiology of psychotic disorders, we thought it would be of interest to examine whether these animals present disturbances in the mesolimbic dopamine system. |
2002-06-21 |
2023-08-12 |
mouse |
| F Cicchetti, A L Brownell, K Williams, Y I Chen, E Livni, O Isacso. Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. The European journal of neuroscience. vol 15. issue 6. 2002-06-12. PMID:11918659. |
degeneration of the dopamine system was monitored by pet imaging of presynaptic dopamine transporters using a specific ligand (11)c-cft (2beta-carbomethoxy-3beta-(4-fluorophenyl) tropane). |
2002-06-12 |
2023-08-12 |
rat |
| M R Picciotto, M Zoli, J P Changeu. Use of knock-out mice to determine the molecular basis for the actions of nicotine. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 1 Suppl 2. 2002-05-22. PMID:11768168. |
experiments using mice lacking the beta2 subunit of the nachr have shown that binding of nicotine to receptors containing this subunit is the first step in a pathway leading to increased dopamine levels in the mesolimbic dopamine system, and ultimately to the behavioral effects of nicotine in a test of nicotine reinforcement. |
2002-05-22 |
2023-08-12 |
mouse |
| Espen Borgå Johansen, Heidi Aase, Anneke Meyer, Terje Sagvolde. Attention-deficit/hyperactivity disorder (ADHD) behaviour explained by dysfunctioning reinforcement and extinction processes. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864716. |
at the neurobiological level, adhd symptoms may to a large extent be caused by a dysfunctioning dopamine system: a dysfunctioning meso-limbo-cortical dopamine branch will produce altered reinforcement and extinction processes, on a behavioural level giving rise to deficient sustained attention, hyperactivity, motor and cognitive impulsiveness. |
2002-05-16 |
2023-08-12 |
Not clear |