| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kehong Zhang, Frank I Tarazi, Eugen Davids, Ross J Baldessarin. Plasticity of dopamine D4 receptors in rat forebrain: temporal association with motor hyperactivity following neonatal 6-hydroxydopamine lesioning. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 26. issue 5. 2002-05-07. PMID:11927187. |
we recently reported that motor hyperactivity in juvenile male rats with neonatal 6-hydroxydopamine lesions of the central dopamine system can be reversed by dopamine d(4) receptor-selective antagonists. |
2002-05-07 |
2023-08-12 |
rat |
| S Kashimur. [New development of hair examination! The searching of hair for the terminal residual substance of pleasant sensation]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. vol 55. issue 3. 2002-04-05. PMID:11905040. |
but extrinsic stimulus as methamphetamine put balance of the homeostasis between dopamine system and gaba system in to disorder, and long term administration of methamphetamine makes long remaining degeneration of synapse of dopamine nerve. |
2002-04-05 |
2023-08-12 |
Not clear |
| S M Stah. Dopamine system stabilizers, aripiprazole, and the next generation of antipsychotics, part 1, "Goldilocks" actions at dopamine receptors. The Journal of clinical psychiatry. vol 62. issue 11. 2002-03-06. PMID:11775041. |
dopamine system stabilizers, aripiprazole, and the next generation of antipsychotics, part 1, "goldilocks" actions at dopamine receptors. |
2002-03-06 |
2023-08-12 |
Not clear |
| J D Elsworth, B A Morrow, R H Rot. Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. Synapse (New York, N.Y.). vol 42. issue 2. 2001-12-04. PMID:11574943. |
here we report that mild footshock stress, which preferentially activates the mesoprefrontal dopamine system, leads to an enhanced increase in dopamine turnover in the ventromedial prefrontal cortex of adolescent (postnatal day 35-37) rats exposed to cocaine in utero, suggesting that the dopamine neurons innervating this region are hyperresponsive in these rats. |
2001-12-04 |
2023-08-12 |
rat |
| A Dagher, C Bleicher, J A Aston, R N Gunn, P B Clarke, P Cummin. Reduced dopamine D1 receptor binding in the ventral striatum of cigarette smokers. Synapse (New York, N.Y.). vol 42. issue 1. 2001-12-04. PMID:11668590. |
this suggests that there is a reduction in dopamine d1 receptor density in the ventral striatum of human cigarette smokers relative to nonsmokers, which implies that the postsynaptic mesolimbic dopamine system may be chronically underactive in smokers, either as an antecedent or consequence of addiction to cigarettes. |
2001-12-04 |
2023-08-12 |
human |
| R M Care. Theodore Cooper Lecture: Renal dopamine system: paracrine regulator of sodium homeostasis and blood pressure. Hypertension (Dallas, Tex. : 1979). vol 38. issue 3. 2001-10-18. PMID:11566894. |
all of the components of a complete dopamine system are present within the kidney, where dopamine acts as a paracrine substance in the control of sodium excretion. |
2001-10-18 |
2023-08-12 |
human |
| Q S Yan, S E Ya. Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 418. issue 1-2. 2001-09-27. PMID:11334865. |
activation of 5-ht(1b/1d) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study. |
2001-09-27 |
2023-08-12 |
rat |
| Q S Yan, S E Ya. Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study. European journal of pharmacology. vol 418. issue 1-2. 2001-09-27. PMID:11334865. |
these results are not in opposition to the concept that 5-ht(1b) receptors within the ventral tegmental area and nucleus accumbens are all involved in the modulation of dopamine release in the terminal area of the mesolimbic dopamine system. |
2001-09-27 |
2023-08-12 |
rat |
| D W Anderson, T Neavin, J A Smith, J S Schneide. Neuroprotective effects of pramipexole in young and aged MPTP-treated mice. Brain research. vol 905. issue 1-2. 2001-09-20. PMID:11423078. |
this study examined the effect of pramipexole (ppx), a selective dopamine (da) d(3)/d(2) agonist, on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced damage to the nigrostriatal dopamine system in young (8-week-old) and aged (12-month-old) mice. |
2001-09-20 |
2023-08-12 |
mouse |
| F M Benes, S Berrett. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 1. 2001-08-02. PMID:11377916. |
the ingrowth of extrinsic afferents, such as the mesocortical dopamine projections, may "trigger" the appearance of a defective gaba system, particularly under stressful conditions when the modulation of the dopamine system is likely to be altered. |
2001-08-02 |
2023-08-12 |
human |
| S L Smith-Roe, A E Kelle. Coincident activation of NMDA and dopamine D1 receptors within the nucleus accumbens core is required for appetitive instrumental learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 20. 2001-06-07. PMID:11027236. |
because it is currently hypothesized that concurrent dopamine d(1) and glutamate receptor activation is required for long-term changes associated with plasticity, we wished to examine whether the dopamine system in the accumbens core modulates learning via nmda receptors. |
2001-06-07 |
2023-08-12 |
Not clear |
| T M Tzschentk. Pharmacology and behavioral pharmacology of the mesocortical dopamine system. Progress in neurobiology. vol 63. issue 3. 2001-03-01. PMID:11115727. |
although the focus of this review is on the mesocortical dopamine system, given the intricate interactions of dopamine with other transmitter systems within the pfc and the importance of the pfc as a source of glutamate in subcortical areas, these aspects are also covered in some detail where appropriate. |
2001-03-01 |
2023-08-12 |
rat |
| N H Mutschler, K A Miczek, R P Hamme. Reduction of zif268 messenger RNA expression during prolonged withdrawal following "binge" cocaine self-administration in rats. Neuroscience. vol 100. issue 3. 2001-01-11. PMID:11098116. |
cocaine self-administration increases dopamine efflux and neuronal activity in the mesocorticolimbic dopamine system compared with experimenter-administered cocaine. |
2001-01-11 |
2023-08-12 |
rat |
| M Soyka, J De Vr. Flupenthixol as a potential pharmacotreatment of alcohol and cocaine abuse/dependence. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 5. 2000-10-30. PMID:10974602. |
preclinical and clinical studies suggest that the mesolimbic dopamine system plays a major role in mediating the reinforcing effects of drugs of abuse, including alcohol and psychostimulants, and that pharmacological blockade of dopamine d1 and/or d2 receptors may reduce intake of these drugs, as well as relapse rates. |
2000-10-30 |
2023-08-12 |
rat |
| P S D'Aquila, A T Peana, V Carboni, G Serr. Exploratory behaviour and grooming after repeated restraint and chronic mild stress: effect of desipramine. European journal of pharmacology. vol 399. issue 1. 2000-08-24. PMID:10876021. |
in a previous study, we have recently shown that chronic treatment with desipramine either reduced or potentiated the locomotor response to the dopamine d(2)-like receptor agonist quinpirole, a behavioural response mediated by the mesolimbic dopamine system, depending on whether the animals were subjected, respectively, to repeated restraint or to chronic mild stress (different stressors randomly presented). |
2000-08-24 |
2023-08-12 |
rat |
| P Muglia, U Jain, F Macciardi, J L Kenned. Adult attention deficit hyperactivity disorder and the dopamine D4 receptor gene. American journal of medical genetics. vol 96. issue 3. 2000-08-10. PMID:10898898. |
convincing evidence supports the contribution of genetic factors in the etiology of adhd, and the interaction of the psychostimulants with the dopamine system suggests that dopamine is involved in the pathophysiology. |
2000-08-10 |
2023-08-12 |
human |
| P Sikiric, J Separovic, G Buljat, T Anic, D Stancic-Rokotov, D Mikus, B Duplancic, A Marovic, I Zoricic, I Prkacin, M Lovric-Bencic, G Aralica, T Ziger, D Perovic, N Jelovac, G Dodig, I Rotkvic, S Mise, S Seiwerth, B Turkovic, Z Grabarevic, M Petek, R Rucma. Gastric mucosal lesions induced by complete dopamine system failure in rats. The effects of dopamine agents, ranitidine, atropine, omeprazole and pentadecapeptide BPC 157. Journal of physiology, Paris. vol 94. issue 2. 2000-07-24. PMID:10791690. |
the failure of dopaminomimetics could be most likely due to more extensive inhibition of endogenous dopamine system activity, and need for remained endogenous dopamine for their salutary effect, whereas the beneficial activities of ranitidine, omeprazole, atropine, pentadecapeptide bpc 157 following dopamine system inhibition by haloperidol+reserpine suggest their corresponding systems parallel those of dopamine system, and they may function despite extensive inhibition of endogenous dopamine system activity. |
2000-07-24 |
2023-08-12 |
rat |
| M van Den Buuse, R Catanzarit. Stimulation of the ventral tegmental area enhances the effect of vasopressin on blood pressure in conscious rats. British journal of pharmacology. vol 129. issue 1. 2000-04-18. PMID:10694199. |
we previously found evidence for a functional interaction between the mesolimbic dopamine system and circulating vasopressin and the present study was performed to test the hypothesis that mesolimbic dopamine stimulation modulates the cardiovascular effects of vasopressin. |
2000-04-18 |
2023-08-12 |
rat |
| U Holtbäck, M S Kruse, H Brismar, A Aperi. Intrarenal dopamine coordinates the effect of antinatriuretic and natriuretic factors. Acta physiologica Scandinavica. vol 168. issue 1. 2000-03-27. PMID:10691803. |
taken together, the observations suggest that dopamine coordinates the effects of antinatriuretic and natriuretic factors and indicate that an intact renal dopamine system is of major importance for the maintenance of sodium homeostasis and normal blood pressure. |
2000-03-27 |
2023-08-12 |
Not clear |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
the results indicate that the mesolimbic and mesocortical dopamine system undergo opposite changes during mecamylamine-precipitated abstinence in rats chronically exposed to nicotine and that physical abstinence signs can be dissociated from changes in dopamine transmission. |
2000-03-14 |
2023-08-12 |
rat |