| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pei-Tseng Lee, Hsuan-Wen Lin, Yu-Hsuan Chang, Tsai-Feng Fu, Josh Dubnau, Jay Hirsh, Tzumin Lee, Ann-Shyn Chian. Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 33. 2011-11-23. PMID:21808003. |
three supporting lines of evidence indicate that arm formation requires 5ht released from only two dorsal paired medial (dpm) neurons onto the mushroom bodies (mbs), the olfactory learning and memory center in drosophila: (i) dpm neurons were 5ht-antibody immunopositive; (ii) temporal inhibition of 5ht synthesis or release from dpm neurons, but not from other serotonergic neurons, impaired arm formation; (iii) knocking down the expression of d5ht1a serotonin receptors in α/β mb neurons, which are innervated by dpm neurons, inhibited arm formation. |
2011-11-23 |
2023-08-12 |
drosophila_melanogaster |
| Eduard Maron, Jakov Shlik, David J Nut. Tryptophan research in panic disorder. International journal of tryptophan research : IJTR. vol 1. 2011-11-23. PMID:22084577. |
research on pathways and functions of tryptophan, an essential amino acid converted into serotonin, may advance our understanding of serotonergic actions in panic disorder and related phenomena. |
2011-11-23 |
2023-08-12 |
Not clear |
| Yukihiro Ohno, Junta Imaki, Yukari Mae, Tsuyoshi Takahashi, Ayaka Tatar. Serotonergic modulation of extrapyramidal motor disorders in mice and rats: role of striatal 5-HT3 and 5-HT6 receptors. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20813116. |
these results suggest that serotonergic stimulation augments extrapyramidal motor disorders by activating the striatal 5-ht(3) and 5-ht(6) receptors and the antagonism of these receptors effectively alleviates antipsychotic-induced eps. |
2011-11-22 |
2023-08-12 |
mouse |
| Thorsten Lau, Tatjana Schneidt, Felix Heimann, Eckart D Gundelfinger, Patrick Schlos. Somatodendritic serotonin release and re-uptake in mouse embryonic stem cell-derived serotonergic neurons. Neurochemistry international. vol 57. issue 8. 2011-11-22. PMID:20959132. |
somatodendritic serotonin release and re-uptake in mouse embryonic stem cell-derived serotonergic neurons. |
2011-11-22 |
2023-08-12 |
mouse |
| Thorsten Lau, Tatjana Schneidt, Felix Heimann, Eckart D Gundelfinger, Patrick Schlos. Somatodendritic serotonin release and re-uptake in mouse embryonic stem cell-derived serotonergic neurons. Neurochemistry international. vol 57. issue 8. 2011-11-22. PMID:20959132. |
about 90% of the resulting neurons exhibited a serotonergic phenotype as judged by immunostaining against serotonin, its synthesising enzyme tryptophan hydroxylase 2, the serotonin transporter as well as 5-ht1(a) and 5-ht1(b) autoreceptors. |
2011-11-22 |
2023-08-12 |
mouse |
| Thorsten Lau, Tatjana Schneidt, Felix Heimann, Eckart D Gundelfinger, Patrick Schlos. Somatodendritic serotonin release and re-uptake in mouse embryonic stem cell-derived serotonergic neurons. Neurochemistry international. vol 57. issue 8. 2011-11-22. PMID:20959132. |
proteins involved in 5-ht release and re-uptake as well as depolarisation evoked exocytosis were evenly co-distributed on neurites and cell bodies suggesting that es cell-derived serotonergic neurons also exhibit somatodendritic release comparable to serotonergic neurons in the raphé nuclei. |
2011-11-22 |
2023-08-12 |
mouse |
| Sylvia Navailles, Bernard Bioulac, Christian Gross, Philippe De Deurwaerdèr. Chronic L-DOPA therapy alters central serotonergic function and L-DOPA-induced dopamine release in a region-dependent manner in a rat model of Parkinson's disease. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:21092759. |
release of l-dopa-derived da depends on the widespread serotonergic (5-ht) innervation in the brain. |
2011-11-22 |
2023-08-12 |
rat |
| Philippe Huot, Susan H Fox, Adrian Newman-Tancredi, Jonathan M Brotchi. Anatomically selective serotonergic type 1A and serotonergic type 2A therapies for Parkinson's disease: an approach to reducing dyskinesia without exacerbating parkinsonism? The Journal of pharmacology and experimental therapeutics. vol 339. issue 1. 2011-11-22. PMID:21784889. |
serotonergic type 1a (5-ht(1a)) receptor agonists and serotonergic type 2a (5-ht(2a)) receptor antagonists were, until recently, considered to be promising therapies against dyskinesia. |
2011-11-22 |
2023-08-12 |
Not clear |
| Philippe Huot, Susan H Fox, Adrian Newman-Tancredi, Jonathan M Brotchi. Anatomically selective serotonergic type 1A and serotonergic type 2A therapies for Parkinson's disease: an approach to reducing dyskinesia without exacerbating parkinsonism? The Journal of pharmacology and experimental therapeutics. vol 339. issue 1. 2011-11-22. PMID:21784889. |
we propose that, in addition to selectivity for specific receptor subtypes, to target 5-ht(1a) and 5-ht(2a) receptors to alleviate dyskinesia, without worsening parkinsonism, it will be necessary to develop compounds that display anatomical selectivity, targeting corticostriatal transmission, while avoiding 5-ht receptors on ascending serotonergic and dopaminergic inputs from the raphe and substantia nigra, respectively. |
2011-11-22 |
2023-08-12 |
Not clear |
| Hiroshi Onogi, Osamu Nakagawasai, Atsushi Sato, Satoru Mitazaki, Kota Nakaya, Kenya Watanabe, Fukie Niijima-Yaoita, Koichi Tan-No, Yuichiro Arai, Tsuneaki Kikuchi, Takeshi Tadan. p-Hydroxyamphetamine causes prepulse inhibition disruption in mice: contribution of serotonin neurotransmission. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21689684. |
haloperidol and clozapine have affinities for serotonergic (especially 5-ht(2a)) receptors. |
2011-11-21 |
2023-08-12 |
mouse |
| William E Wood, Peter V Lovell, Claudio V Mello, David J Perke. Serotonin, via HTR2 receptors, excites neurons in a cortical-like premotor nucleus necessary for song learning and production. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 39. 2011-11-21. PMID:21957243. |
birds also have serotonergic neurons in the dorsal raphe, suggesting that 5-ht plays similar roles in sensory and motor processing, perhaps modulating brain circuitry underlying birdsong. |
2011-11-21 |
2023-08-12 |
Not clear |
| José J Rodríguez, Harun N Noristani, Walter B Hoover, Stephanie B Linley, Robert P Verte. Serotonergic projections and serotonin receptor expression in the reticular nucleus of the thalamus in the rat. Synapse (New York, N.Y.). vol 65. issue 9. 2011-11-15. PMID:21308802. |
in addition, serotonergic fibers (5-ht and sert positive) were richly distributed throughout rt, and 5-ht(1a) and 5-ht(2a) receptors were highly expressed on rt neurons and dendrites. |
2011-11-15 |
2023-08-12 |
rat |
| Clare M Mathes, Alan C Specto. The selective serotonin reuptake inhibitor paroxetine does not alter consummatory concentration-dependent licking of prototypical taste stimuli by rats. Chemical senses. vol 36. issue 6. 2011-11-08. PMID:21422376. |
serotonergic agonists also decrease food and fluid intake, and it is possible that modulations of serotonin may alter taste-based hedonic responsiveness; alternatively, or in combination, serotonin may interact with physiological state to impact ingestive behavior. |
2011-11-08 |
2023-08-12 |
rat |
| K W Whitaker, H Neumeister, L S Huffman, C E Kidd, T Preuss, H A Hofman. Serotonergic modulation of startle-escape plasticity in an African cichlid fish: a single-cell molecular and physiological analysis of a vital neural circuit. Journal of neurophysiology. vol 106. issue 1. 2011-11-08. PMID:21451063. |
immunohistochemistry showed serotonergic varicosities around the m-cells, further suggesting that 5-ht impinges directly onto the startle-escape circuitry. |
2011-11-08 |
2023-08-12 |
Not clear |
| James W Murrough, Christoph Czermak, Shannan Henry, Nabeel Nabulsi, Jean-Dominique Gallezot, Ralitza Gueorguieva, Beata Planeta-Wilson, John H Krystal, John F Neumaier, Yiyun Huang, Yu-Shin Ding, Richard E Carson, Alexander Neumeiste. The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding. Archives of general psychiatry. vol 68. issue 9. 2011-11-08. PMID:21893657. |
serotonergic dysfunction is implicated in the pathogenesis of posttraumatic stress disorder (ptsd), and recent animal models suggest that disturbances in serotonin type 1b receptor function, in particular, may contribute to chronic anxiety. |
2011-11-08 |
2023-08-12 |
Not clear |
| D Calderón Guzmán, E Bratoeff, E Ramírez López, E Hernández García, F Pierdant Rioja, N Osnaya Brizuela, F Trujillo Jiménez, G Barragán Mejía, H Juárez Olguín, D Santamaría Del Ánge. Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate. Andrologia. vol 43. issue 4. 2011-11-07. PMID:21486400. |
5-ht increased in group a and the prostate weight was increased in group e. the conclusion is that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be considered novel and promising to treat androgen-dependent diseases and epilepsy, since it showed an antioxidant effect and seemed to impair the gabaergic and serotonergic metabolism. |
2011-11-07 |
2023-08-12 |
rat |
| Leandro Fernandes Malloy-Diniz, Fernando Silva Neves, Paulo Henrique Paiva de Moraes, Luiz Armando De Marco, Marco Aurélio Romano-Silva, Marie-Odile Krebs, Humberto Corrê. The 5-HTTLPR polymorphism, impulsivity and suicide behavior in euthymic bipolar patients. Journal of affective disorders. vol 133. issue 1-2. 2011-11-07. PMID:21550122. |
furthermore they are, impulsivity, bd and suicide behavior, associated with serotonergic function, at least partially, under genetic determinism and somewhat associated with the serotonin transporter gene polymorphism, the 5-httlpr. |
2011-11-07 |
2023-08-12 |
Not clear |
| Anne Jaerve, Nora Schiwy, Christine Schmitz, Hans W Muelle. Differential effect of aging on axon sprouting and regenerative growth in spinal cord injury. Experimental neurology. vol 231. issue 2. 2011-11-02. PMID:21806987. |
we found that aging significantly reduces spontaneous axon sprouting of corticospinal (cst), serotonergic (5-ht) raphespinal and catecholaminergic (th) coerulospinal tracts in distinct regions of the spinal cord rostral to the lesion. |
2011-11-02 |
2023-08-12 |
rat |
| Philippe Huot, Jonathan M Brotchi. 5-HT(1A) receptor stimulation and L-DOPA-induced dyskinesia in Parkinson's disease: bridging the gap between serotonergic and glutamatergic mechanisms. Experimental neurology. vol 231. issue 2. 2011-11-02. PMID:21819982. |
5-ht(1a) receptor stimulation and l-dopa-induced dyskinesia in parkinson's disease: bridging the gap between serotonergic and glutamatergic mechanisms. |
2011-11-02 |
2023-08-12 |
Not clear |
| Romain Meeusen, Phil Watso. Amino acids and the brain: do they play a role in "central fatigue"? International journal of sport nutrition and exercise metabolism. vol 17 Suppl. 2011-10-31. PMID:18577773. |
the rates of 5-ht and da/na synthesis largely depend on the peripheral availability of the amino acids tryptophan (trp) and tyrosine (tyr), with increased brain delivery increasing serotonergic and da/na activity, respectively. |
2011-10-31 |
2023-08-12 |
rat |