| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sören Enge, Monika Fleischhauer, Klaus-Peter Lesch, Andreas Reif, Alexander Strobe. Serotonergic modulation in executive functioning: linking genetic variations to working memory performance. Neuropsychologia. vol 49. issue 13. 2012-03-05. PMID:21983350. |
in the current study, we aimed at extending this evidence by using the n-back task to examine working memory performance of 130 participants via behavioral and neurophysiological indices and by focusing on variations within genes encoding key regulators of the serotonergic system: the serotonin transporter gene-linked polymorphic region (5-httlpr) and a repeat polymorphism in the transcriptional control region of the monoamine-oxidase gene (maoa-uvntr). |
2012-03-05 |
2023-08-12 |
human |
| Agustina Falibene, Wolfgang Rössler, Roxana Josen. Serotonin depresses feeding behaviour in ants. Journal of insect physiology. vol 58. issue 1. 2012-03-01. PMID:21893064. |
although the frontal and suboesophageal ganglia contained 5-ht immunoreactive cell bodies, serotonergic innervation in the sucking-pump muscles was absent. |
2012-03-01 |
2023-08-12 |
Not clear |
| Ryosuke Takenaka, Yoshiaki Ohi, Akira Haj. Distinct modulatory effects of 5-HT on excitatory synaptic transmissions in the nucleus tractus solitarius of the rat. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21968141. |
serotonin (5-ht) is an important candidate for such neuromodulators, since serotonergic inputs and distribution of 5-ht receptors are provided in the nts. |
2012-03-01 |
2023-08-12 |
rat |
| Ryosuke Takenaka, Yoshiaki Ohi, Akira Haj. Distinct modulatory effects of 5-HT on excitatory synaptic transmissions in the nucleus tractus solitarius of the rat. European journal of pharmacology. vol 671. issue 1-3. 2012-03-01. PMID:21968141. |
to evaluate the serotonergic modulation of synaptic transmission, we examined the effects of 5-ht (1.0-10.0 μm) on the solitary tract-evoked excitatory postsynaptic currents (eepscs) and spontaneously occurring epscs (sepscs) in the preselected second-order neurons of the rat nts. |
2012-03-01 |
2023-08-12 |
rat |
| Charles H K West, Katherine A Boss-Williams, Jay M Weis. Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress. Alcohol (Fayetteville, N.Y.). vol 45. issue 8. 2012-02-28. PMID:21924578. |
because serotonergic function has often been shown to be involved in the regulation of alcohol consumption, here we examined the effects of manipulations of serotonin transmission on intake of ethanol by sus rats. |
2012-02-28 |
2023-08-12 |
rat |
| Charles H K West, Katherine A Boss-Williams, Jay M Weis. Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress. Alcohol (Fayetteville, N.Y.). vol 45. issue 8. 2012-02-28. PMID:21924578. |
the 8-oh-dpat increased ethanol intake at lower doses, presumably acting at autoreceptors, which inhibit serotonergic neurons, and decreased intake at higher doses, presumably acting at postsynaptic 5-ht(1a) receptors. |
2012-02-28 |
2023-08-12 |
rat |
| K Saka. Sleep-waking discharge profiles of dorsal raphe nucleus neurons in mice. Neuroscience. vol 197. 2012-02-27. PMID:21958868. |
of the 212 w-active neurons, 194 were judged serotonergic (5-ht w-active neurons) because of their triphasic long-duration action potential and low rate of spontaneous discharge, while the remaining 18 were judged non-serotonergic (non-5-ht w-active neurons) because of their biphasic narrow action potential and higher rate of spontaneous discharge. |
2012-02-27 |
2023-08-12 |
mouse |
| C M Ciarleglio, H E S Resuehr, D G McMaho. Interactions of the serotonin and circadian systems: nature and nurture in rhythms and blues. Neuroscience. vol 197. 2012-02-27. PMID:21963350. |
these master regulatory networks of the brain are extensively intertwined, with reciprocal circuit connections, expression of key genetic elements for serotonin signaling in clock neurons and expression of key clock genes in serotonergic neurons. |
2012-02-27 |
2023-08-12 |
Not clear |
| Michael L Huynh, Elena Rivkin, Ryan Mui, Sabine P Corde. A tryptophan hydroxlyase 1 reporter that directs Cre recombinase extinguishable placental alkaline phosphatase expression in serotonergic (5-HT) neurons and peripheral tissues. Genesis (New York, N.Y. : 2000). vol 49. issue 11. 2012-02-24. PMID:21438125. |
a tryptophan hydroxlyase 1 reporter that directs cre recombinase extinguishable placental alkaline phosphatase expression in serotonergic (5-ht) neurons and peripheral tissues. |
2012-02-24 |
2023-08-12 |
mouse |
| Michael L Huynh, Elena Rivkin, Ryan Mui, Sabine P Corde. A tryptophan hydroxlyase 1 reporter that directs Cre recombinase extinguishable placental alkaline phosphatase expression in serotonergic (5-HT) neurons and peripheral tissues. Genesis (New York, N.Y. : 2000). vol 49. issue 11. 2012-02-24. PMID:21438125. |
the serotonergic (5-ht) system modulates many behaviors and has been implicated in psychiatric disorders, but the density of 5-ht processes has complicated analyses. |
2012-02-24 |
2023-08-12 |
mouse |
| Ross A McDevitt, John F Neumaie. Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective. Journal of chemical neuroanatomy. vol 41. issue 4. 2012-02-22. PMID:21620956. |
neurotransmission by serotonin (5-ht) is tightly regulated by several autoreceptors that fine-tune serotonergic neurotransmission through negative feedback inhibition at the cell bodies (predominantly 5-ht(1a)) or at the axon terminals (predominantly 5-ht(1b)); however, more subtle roles for 5-ht(1d) and 5-ht(2b) autoreceptors have also been detected. |
2012-02-22 |
2023-08-12 |
Not clear |
| Ross A McDevitt, John F Neumaie. Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective. Journal of chemical neuroanatomy. vol 41. issue 4. 2012-02-22. PMID:21620956. |
experiments targeting 5-ht autoreceptors in awake, behaving animals have generally shown that increasing autoreceptor feedback is anxiolytic and rewarding, while enhanced 5-ht function is aversive and anxiogenic; however, the role of serotonergic activity in behavioral models of helplessness is more complex. |
2012-02-22 |
2023-08-12 |
Not clear |
| Hannah C Kinney, Kevin G Broadbelt, Robin L Haynes, Ingvar J Rognum, David S Paterso. The serotonergic anatomy of the developing human medulla oblongata: implications for pediatric disorders of homeostasis. Journal of chemical neuroanatomy. vol 41. issue 4. 2012-02-22. PMID:21640183. |
the caudal serotonergic (5-ht) system is a critical component of a medullary "homeostatic network" that regulates protective responses to metabolic stressors such as hypoxia, hypercapnia, and hyperthermia. |
2012-02-22 |
2023-08-12 |
human |
| Joseph M Furman, Dawn A Marcus, Carey D Balaba. Rizatriptan reduces vestibular-induced motion sickness in migraineurs. The journal of headache and pain. vol 12. issue 1. 2012-02-16. PMID:20862509. |
we conclude that the serotonin agonist, rizatriptan, reduces vestibular-induced motion sickness by influencing serotonergic vestibular-autonomic projections. |
2012-02-16 |
2023-08-12 |
human |
| Diane C Chugan. α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions. Biomarkers in medicine. vol 5. issue 5. 2012-02-14. PMID:22003905. |
this tracer was first applied in patients with medically refractory epilepsy in an attempt to detect changes in serotonin synthesis based upon reports of increased serotonergic innervation in cortical specimens obtained following epilepsy surgery. |
2012-02-14 |
2023-08-12 |
Not clear |
| Charlotte Brasch-Andersen, Malik U Møller, Lene Christiansen, Mikael Thinggaard, Marit Otto, Kim Brøsen, Søren H Sindru. A candidate gene study of serotonergic pathway genes and pain relief during treatment with escitalopram in patients with neuropathic pain shows significant association to serotonin receptor2C (HTR2C). European journal of clinical pharmacology. vol 67. issue 11. 2012-02-13. PMID:21614492. |
a candidate gene study of serotonergic pathway genes and pain relief during treatment with escitalopram in patients with neuropathic pain shows significant association to serotonin receptor2c (htr2c). |
2012-02-13 |
2023-08-12 |
Not clear |
| Shu-Yan Yu, Gui-Min Wang, Hui Wang, Hui Zhang, Qin L. Raphe pallidus modulates Bötzinger complex-induced inhibition of the phrenic nerve activity in rats. The European journal of neuroscience. vol 34. issue 7. 2012-02-10. PMID:21895801. |
in the present study, we examined the modulatory effects of serotonergic (5-hydroxytryptamine, 5-ht) rpa neurons on the inhibitory response of the phrenic nerve activity elicited from the bötc in rats. |
2012-02-10 |
2023-08-12 |
rat |
| Yu Zhang, Aihui Li, Jiajia Xin, Lixing Lao, Ke Ren, Brian M Berman, Ming Tan, Rui-Xin Zhan. Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model. Neurochemical research. vol 36. issue 10. 2012-02-08. PMID:21556842. |
the present study investigated the effects of intrathecal 5,7-dihydroxytryptamine creatinine sulfate, a selective neurotoxin for serotonergic terminals, the 5-hydroxytryptamine 1a receptor (5-ht1ar) antagonist nan-190 hydrobromide and the 5-ht2c receptor (5-ht2cr) antagonist sb-242,084 on ea anti-hyperalgesia. |
2012-02-08 |
2023-08-12 |
rat |
| Kyoko Nishi, Sho Takahashi, Mirko Diksi. Densities of serotonergic projections as revealed by in situ synthesised labelled α-methyl-serotonin: an autoradiographic evaluation. Neurochemical research. vol 36. issue 8. 2012-02-01. PMID:21472458. |
an estimate of serotonergic innervation density and regional serotonin (5-ht) concentration was performed from the distribution of in situ produced labelled α-methyl-serotonin. |
2012-02-01 |
2023-08-12 |
rat |
| Kyoko Nishi, Sho Takahashi, Mirko Diksi. Densities of serotonergic projections as revealed by in situ synthesised labelled α-methyl-serotonin: an autoradiographic evaluation. Neurochemical research. vol 36. issue 8. 2012-02-01. PMID:21472458. |
based on this, and the assumption that the specific activity of in situ produced α-methyl-serotonin is the same as that of the injected tracer, it was possible to estimate the regional concentrations of 5-ht and the relative concentration of regional serotonergic innervations. |
2012-02-01 |
2023-08-12 |
rat |