| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F E Perrin, Y N Gerber, M Teigell, N Lonjon, G Boniface, L Bauchet, J J Rodriguez, J P Hugnot, A M Priva. Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord. Cell death & disease. vol 2. 2012-04-10. PMID:21993394. |
anatomical study of serotonergic innervation and 5-ht(1a) receptor in the human spinal cord. |
2012-04-10 |
2023-08-12 |
human |
| F E Perrin, Y N Gerber, M Teigell, N Lonjon, G Boniface, L Bauchet, J J Rodriguez, J P Hugnot, A M Priva. Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord. Cell death & disease. vol 2. 2012-04-10. PMID:21993394. |
here, we have performed a preliminary mapping of serotonergic processes and serotonin-la (5-ht(1a)) receptors in thoracic and lumbar segments of the human spinal cord. |
2012-04-10 |
2023-08-12 |
human |
| F E Perrin, Y N Gerber, M Teigell, N Lonjon, G Boniface, L Bauchet, J J Rodriguez, J P Hugnot, A M Priva. Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord. Cell death & disease. vol 2. 2012-04-10. PMID:21993394. |
finally, we observed numerous serotonergic profiles in the superficial part (equivalent of rexed lamina ii) of the dorsal horn, which also displayed high levels of 5-ht(1a) receptors. |
2012-04-10 |
2023-08-12 |
human |
| Tillmann Weber, Kai Schönig, Björn Tews, Dusan Bartsc. Inducible gene manipulations in brain serotonergic neurons of transgenic rats. PloS one. vol 6. issue 11. 2012-04-09. PMID:22140568. |
the serotonergic (5-ht) system has been implicated in various physiological processes and neuropsychiatric disorders, but in many aspects its role in normal and pathologic brain function is still unclear. |
2012-04-09 |
2023-08-12 |
mouse |
| Tillmann Weber, Kai Schönig, Björn Tews, Dusan Bartsc. Inducible gene manipulations in brain serotonergic neurons of transgenic rats. PloS one. vol 6. issue 11. 2012-04-09. PMID:22140568. |
this 5-ht neuron specific creert2 line allows cre-mediated, inducible gene deletion or gene overexpression in transgenic rats which provides new opportunities to decipher the complex functions of the mammalian serotonergic system. |
2012-04-09 |
2023-08-12 |
mouse |
| Jesper T Andreasen, Elsebet Ø Nielsen, Jeppe K Christensen, Gunnar M Olsen, Dan Peters, Naheed R Mirza, John P Redrob. Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test. Journal of psychopharmacology (Oxford, England). vol 25. issue 10. 2012-04-06. PMID:20360159. |
nicotine increases serotonergic and noradrenergic neuronal activity and facilitates serotonin and noradrenaline release. |
2012-04-06 |
2023-08-12 |
mouse |
| Adjmal Nahimi, Mette Høltzermann, Anne M Landau, Mette Simonsen, Steen Jakobsen, Aage Kristian Olsen Alstrup, Kim Vang, Arne Møller, Gregers Wegener, Albert Gjedde, Doris J Doude. Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. Journal of neurochemistry. vol 120. issue 5. 2012-04-05. PMID:22117574. |
the reversal of the effect of l-dopa on [(11) c]raclopride binding, extracellular da and lid by 5-ht agonist administration is consistent with the notion that part of the da increase associated with lid originates in serotonergic neurons. |
2012-04-05 |
2023-08-12 |
rat |
| X Zhang, P J Nicholls, G Laje, T D Sotnikova, R R Gainetdinov, P R Albert, G Rajkowska, C A Stockmeier, M C Speer, D C Steffens, M C Austin, F J McMahon, K R R Krishnan, M A Garcia-Blanco, M G Caro. A functional alternative splicing mutation in human tryptophan hydroxylase-2. Molecular psychiatry. vol 16. issue 12. 2012-03-27. PMID:20856248. |
the brain serotonergic system has an essential role in the physiological functions of the central nervous system and dysregulation of serotonin (5-ht) homeostasis has been implicated in many neuropsychiatric disorders. |
2012-03-27 |
2023-08-12 |
human |
| X Zhang, P J Nicholls, G Laje, T D Sotnikova, R R Gainetdinov, P R Albert, G Rajkowska, C A Stockmeier, M C Speer, D C Steffens, M C Austin, F J McMahon, K R R Krishnan, M A Garcia-Blanco, M G Caro. A functional alternative splicing mutation in human tryptophan hydroxylase-2. Molecular psychiatry. vol 16. issue 12. 2012-03-27. PMID:20856248. |
the tryptophan hydroxylase-2 (tph2) gene is the rate-limiting enzyme in brain 5-ht synthesis, and thus is an ideal candidate gene for understanding the role of dysregulation of brain serotonergic homeostasis. |
2012-03-27 |
2023-08-12 |
human |
| Roger S McIntyr. Asenapine: a review of acute and extension phase data in bipolar disorder. CNS neuroscience & therapeutics. vol 17. issue 6. 2012-03-25. PMID:20950326. |
asenapine exhibits a high affinity for and antagonism at several serotonergic (5-ht(2a-c), 5ht(5a), 5ht(6), 5ht(7)), dopaminergic (d(2), d(3)), alpha-adrenergic (α(1) and α(2)), and histaminergic (h1, h2) receptor subtypes. |
2012-03-25 |
2023-08-12 |
Not clear |
| Vasiliki Michopoulos, Sarah L Berga, Mark E Wilso. Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. Experimental and clinical psychopharmacology. vol 19. issue 6. 2012-03-25. PMID:21843009. |
estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. |
2012-03-25 |
2023-08-12 |
monkey |
| Vasiliki Michopoulos, Sarah L Berga, Mark E Wilso. Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. Experimental and clinical psychopharmacology. vol 19. issue 6. 2012-03-25. PMID:21843009. |
indeed, estradiol and progesterone, the primary female steroid hormones, exert an array of effects on the serotonergic system, including 5htt expression. |
2012-03-25 |
2023-08-12 |
monkey |
| Vera Kiyasova, Patricia Gaspa. Development of raphe serotonin neurons from specification to guidance. The European journal of neuroscience. vol 34. issue 10. 2012-03-19. PMID:22103413. |
the main features of the development of the serotonin (5-ht) raphe neurons have been known for many years but more recent molecular studies, using mouse genetics, have since unveiled several intriguing aspects of the specification of the raphe serotonergic system. |
2012-03-19 |
2023-08-12 |
mouse |
| Vera Kiyasova, Patricia Gaspa. Development of raphe serotonin neurons from specification to guidance. The European journal of neuroscience. vol 34. issue 10. 2012-03-19. PMID:22103413. |
here we overview recent progress made in the understanding of the developmental programming of serotonergic neurons in the mouse raphe, emphasizing data showing how heterogeneous subsets of 5-ht neurons may be generated. |
2012-03-19 |
2023-08-12 |
mouse |
| J C Beucke, M Plotkin, C Winter, T Endrass, H Amthauer, G Juckel, A Kupsc. Midbrain serotonin transporters in de novo and L-DOPA-treated patients with early Parkinson's disease--a [123 I]-ADAM SPECT study. European journal of neurology. vol 18. issue 5. 2012-03-16. PMID:21143705. |
in contrast, temporal characteristics of serotonergic markers like the serotonin transporter (sert) in relation to clinical staging of pd and dopaminergic cell loss are less clear. |
2012-03-16 |
2023-08-12 |
Not clear |
| Philippe Huot, Tom H Johnston, Lieke Winkelmolen, Susan H Fox, Jonathan M Brotchi. 5-HT2A receptor levels increase in MPTP-lesioned macaques treated chronically with L-DOPA. Neurobiology of aging. vol 33. issue 1. 2012-03-13. PMID:20561716. |
there are clear functional interactions between dopaminergic and serotonergic type 2a receptors (5-ht(2a))-mediated neurotransmission. |
2012-03-13 |
2023-08-12 |
Not clear |
| Philippe Huot, Tom H Johnston, James B Koprich, Lieke Winkelmolen, Susan H Fox, Jonathan M Brotchi. Regulation of cortical and striatal 5-HT1A receptors in the MPTP-lesioned macaque. Neurobiology of aging. vol 33. issue 1. 2012-03-13. PMID:21051107. |
serotonergic 1a (5-ht(1a)) receptor agonists reduce l-3,4-dihydroxyphenylalanine (l-dopa)-induced dyskinesia in parkinson's disease (pd), though the mechanism(s) and site(s) of action remain unclear. |
2012-03-13 |
2023-08-12 |
monkey |
| Jiangnan Luo, Jaime Becnel, Charles D Nichols, Dick R Nässe. Insulin-producing cells in the brain of adult Drosophila are regulated by the serotonin 5-HT1A receptor. Cellular and molecular life sciences : CMLS. vol 69. issue 3. 2012-03-06. PMID:21818550. |
we show that the ipcs in adult flies express the 5-ht(1a), but not the 5-ht(1b) or 5-ht(7) receptors, and that processes of serotonergic neurons impinge on the ipc branches. |
2012-03-06 |
2023-08-12 |
drosophila_melanogaster |
| Y M Qiu, Y T Liu, S T L. Tramadol requirements may need to be increased for the perioperative management of pain in smokers. Medical hypotheses. vol 77. issue 6. 2012-03-06. PMID:22001127. |
the serotonergic system plays an important part in modulating anti-nociception, and decreasing the concentration of serotonin in vesicles in neurons of the brain and spinal cord is an effective method. |
2012-03-06 |
2023-08-12 |
Not clear |
| Sarah Hohmann, Nina Schweinfurth, Thorsten Lau, Michael Deuschle, Florian Lederbogen, Tobias Banaschewski, Patrick Schlos. Differential expression of neuronal dopamine and serotonin transporters DAT and SERT in megakaryocytes and platelets generated from human MEG-01 megakaryoblasts. Cell and tissue research. vol 346. issue 2. 2012-03-06. PMID:22006250. |
in the central nervous system, serotonergic and dopaminergic signaling is terminated by the activity of specialized transporter proteins for serotonin (sert) and dopamine (dat). |
2012-03-06 |
2023-08-12 |
human |